| Not Yet Recruiting | Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvo NCT07515651 | University Health Network, Toronto | Phase 2 |
| Not Yet Recruiting | Advancing Care Coordination Between Cancer and Primary Care Teams for Complex Cancer Survivors NCT06834204 | Rutgers, The State University of New Jersey | N/A |
| Recruiting | PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanc NCT07426055 | Affidea Nu-med Center of Oncological DIagnostics and Therapy | Phase 2 / Phase 3 |
| Not Yet Recruiting | PRIAPUS-PCa Study: Stereotactic Body Radiation Therapy (SBRT) and Androgen Deprivation Therapy (ADT) Impact on NCT07460726 | CancerCare Manitoba | — |
| Not Yet Recruiting | Rezvilutamide for High-Risk Prostate Cancer After Surgery NCT07444983 | Fujian Medical University Union Hospital | N/A |
| Recruiting | LUtetium-177 DOsimetry as a Predictive Biomarker of Response in Metastatic Prostate Cancer Patients Treated Wi NCT07370597 | Jules Bordet Institute | — |
| Enrolling By Invitation | Predictive Factors for 10-year Biochemical Recurrence and Urinary Continence Following Robot-assisted Radical NCT07439913 | F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica | — |
| Not Yet Recruiting | A Single-Arm, Blinded, Fluorescent PSMA Histopathology Trial of AS1986NS NCT06906471 | Antelope Surgical Solutions, Inc | Phase 1 / Phase 2 |
| Not Yet Recruiting | Safety and Efficacy Evaluation of LC-K76 in Patients With Metastatic Hormone-Sensitive Prostate Cancer NCT07389174 | Shanghai Changzheng Hospital | EARLY_Phase 1 |
| Recruiting | ABlative Radiotherapy (for) Unfavorable Prostate Tumors 2.0 NCT07407608 | University of Milano Bicocca | — |
| Recruiting | Navigation, Outcomes and Quality-of-life in Prostate Cancer Patients Undergoing PSMA-targeted Surgery NCT07129551 | Martini-Klinik am UKE GmbH | N/A |
| Recruiting | Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Me NCT06957691 | Shehzad Basaria, M.D. | Phase 2 |
| Not Yet Recruiting | Percutaneous Thermo-ablation for the Treatment of Prostate Cancer Oligometastatasis (TA-P-OLIM) NCT07237399 | University Hospital, Ghent | — |
| Not Yet Recruiting | Phase I Study of Docetaxel and 177-Lutetium-PSMA-I&T in First-Line Treatment for Patients With Metastatic Cast NCT07316686 | Instituto do Cancer do Estado de São Paulo | Phase 1 |
| Recruiting | The Value of GRPR PET Imaging for Diagnosis and Staging in Prostate Cancer NCT07363382 | First Affiliated Hospital of Fujian Medical University | Phase 1 / Phase 2 |
| Active Not Recruiting | REDI-CaP(Recovery of Erectile Dysfunction Induced in Prostate Cancer Patients) NCT07302451 | National Cancer Institute, Naples | Phase 2 |
| Not Yet Recruiting | CONVERT-HB1: Radical Prostatectomy After Systemic Therapy for High-volume Metastatic Hormone-sensitive Prostat NCT07268794 | Fudan University | Phase 2 |
| Recruiting | PSMA PET for Surveillance After Focal Therapy NCT07115914 | University of Chicago | N/A |
| Recruiting | Adaptive Stereotactic Radiotherapy for Localized Prostate Cancer NCT07344844 | Clinique Sainte Clotilde | N/A |
| Recruiting | Dose De-escalation in Prostate Radiotherapy Using an MR-Linac in Two Fractions NCT07391982 | The Netherlands Cancer Institute | N/A |
| Recruiting | A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec NCT07332000 | Candel Therapeutics, Inc. | Phase 2 |
| Recruiting | Dyadic Co-learning Intervention for Patients With Prostate Cancer and Their Spouses NCT07196488 | National Taipei University of Nursing and Health Sciences | N/A |
| Recruiting | A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Receive NCT06844383 | Prostate Cancer Clinical Trials Consortium | Phase 2 |
| Recruiting | Adaptive Radiation Therapy for Men With Intermediate- or High-Risk Prostate Cancer NCT07219303 | Fox Chase Cancer Center | N/A |
| Recruiting | Sacituzumab Tirumotecan in Combination With Tagitanlimab in the Treatment of Aggressive Variant Prostate Cance NCT07179783 | Tianjin Medical University Second Hospital | Phase 2 |
| Recruiting | Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer NCT07182279 | The Methodist Hospital Research Institute | Phase 1 / Phase 2 |
| Recruiting | Study of the Epidemiological, Clinical, Diagnostic, and Therapeutic Characteristics of Prostate Cancers in Alg NCT07484971 | Société Algérienne de Formation et Recherche en Oncologie | — |
| Recruiting | Personalization of External Beam Radiation Therapy in Localised Tumours NCT07047495 | European Institute of Oncology | — |
| Recruiting | Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Ca NCT06592924 | Canadian Cancer Trials Group | Phase 3 |
| Recruiting | Flotufolastat F 18 PET in Men With Very Low PSA Recurrence NCT06862856 | Massachusetts General Hospital | — |
| Recruiting | Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer NCT06801236 | Acerand Therapeutics (Hong Kong) Limited | Phase 1 |
| Recruiting | Micro-ultrasound-Guided Focal Laser Ablation for Intermediate-Risk Prostate Cancer: Safety & Effectiveness NCT07339943 | University Health Network, Toronto | N/A |
| Not Yet Recruiting | Evaluation of the PROSTia Test in Patients Undergoing Prostate Biopsy NCT06931496 | Central Hospital, Nancy, France | N/A |
| Not Yet Recruiting | Robotic Prostatectomy Artificial Intelligence Low Pressure Pain (RALP) Trial NCT06915909 | East and North Hertfordshire NHS Trust | N/A |
| Not Yet Recruiting | Effect of ADT and ARPI on Bone Loss of Patients with Prostate Cancer NCT06838520 | The First Affiliated Hospital with Nanjing Medical University | — |
| Not Yet Recruiting | Comparison Between HUGO RAS Robotic Platform and Da Vinci Robotic Platform NCT06844513 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | N/A |
| Recruiting | Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic NCT06926374 | Chinese University of Hong Kong | N/A |
| Not Yet Recruiting | Optimal Duration of Hormonal Therapy for Unfavorable Intermediate-risk Prostate Cancer Patients: 6 Versus 12 M NCT06855589 | Charles LeMoyne Hospital | Phase 3 |
| Recruiting | A Study of HLD-0915 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC) NCT06800313 | Halda Therapeutics OpCo, Inc. | Phase 1 / Phase 2 |
| Recruiting | Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients NCT06616597 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 2 |
| Terminated | Registry to Evaluate Long-Term Outcomes in Patients Who Undergo 68-Ga-PSMA-11 PET/CT Imaging Evaluations NCT06655064 | Telix Pharmaceuticals (Innovations) Pty Limited | — |
| Enrolling By Invitation | ProA Study: ProActive Management Model in Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated by Apal NCT06865547 | Yonghong Li | — |
| Recruiting | EFFICACY of INTRAOPERATIVE ARISTA POLYSACCHARIDE APPLICATION on the POSTOPERATIVE BLOOD LOSS in PATIENTS UNDER NCT06822036 | St. Antonius Hospital Gronau | N/A |
| Recruiting | Impact of [18F] PSMA-1007 Imaging for Primary Staging of Prostate Cancer NCT06820333 | Heinrich-Heine University, Duesseldorf | — |
| Recruiting | The Impact of Metastatic Directed Radiotherapy (MDRT) on Oligoprogressive Castration Resistant Prostate Cancer NCT07038304 | University Medical Center Groningen | Phase 2 |
| Recruiting | Understanding the Benefits of Dietary Fibre Supplementation in Patients With Prostate Cancer NCT06661044 | University of Aberdeen | — |
| Recruiting | Stereotactic Radiotherapy of Prostate Cancer With Reduction of Safety Margins NCT06665932 | University Hospital Ostrava | N/A |
| Recruiting | Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer NCT06631521 | AdventHealth | Phase 1 |
| Recruiting | FK-PC101 as Adjuvant Therapy for Men With High-Risk Prostate Cancer NCT06636682 | Cellvax Therapeutics Inc | Phase 2 |
| Recruiting | 68Ga-P16-093 PET Imaging for Diagnosing Prostate Cancer, a Head-to-head Comparison With mpMRI NCT07209865 | First Affiliated Hospital of Fujian Medical University | Phase 1 / Phase 2 |
| Recruiting | 68Ga-AAZTA-NI-093 PET/CT: First-in-human Study NCT06612580 | First Affiliated Hospital of Fujian Medical University | EARLY_Phase 1 |
| Recruiting | Online Adaptive Stereotactic Body Radiotherapy for Localized Prostate Cancer (X-SMILE) NCT06834152 | University of Zurich | — |
| Recruiting | Prostatic Size Reduction Following of Leuprorelin Acetate NCT06184464 | Consorci Sanitari de Terrassa | — |
| Recruiting | Prognostic Value of Early Postoperative Prostate-Specific Antigen for Oncological Outcomes After Radical Prost NCT07516886 | Lithuanian University of Health Sciences | — |
| Completed | Robot-Assisted Radical Prostatectomy: the HOOD Technique Versus Standard Anterior Reconstruction NCT07417475 | Araz Musaev | N/A |
| Completed | Genetic Studies of Prostate Cancer Aggressiveness and Prognosis NCT06773858 | Karolinska Institutet | — |
| Unknown | Use of Indocyanine Green in Robotic Prostate Surgeries NCT05960149 | Ankara University | Phase 4 |
| Recruiting | Assessment of ADC Values and Radiomics Characteristics With a MRI of the Prostate to Identify Tumor Lesions NCT06774781 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Terminated | Trial of NanoPac Focal Therapy for Prostate Cancer NCT04221828 | NanOlogy, LLC | Phase 2 |
| Completed | Development of a Novel Signature Integrating Clinical, Imaging And Epigenetic Information to Tailor Pelvic Nod NCT06807398 | Francesco Montorsi | — |
| Completed | Investigation of the Diagnostic Role of miRNAs in PCa and BPH NCT06726070 | Alanya Alaaddin Keykubat University | — |
| Completed | Efficacy and Safety of VasoClip® vs. WeckClip® for Robotic Urologic Surgery NCT07413120 | Incheon St.Mary's Hospital | Phase 3 |
| Terminated | Immediate Prostatectomy vs. Cabozantinib Followed by Prostatectomy in Men With High-Risk Prostate Cancer NCT03964337 | Duke University | Phase 2 |
| Enrolling By Invitation | RegisterPROS - a Registry for Prostate Cancers NCT06872619 | Wren Laboratories LLC | — |
| Recruiting | 68Ga-PSMA-11 PET Imaging for Diagnosing Prostate Cancer, a Head-to-head Comparison With mpMRI NCT07209878 | First Affiliated Hospital of Fujian Medical University | Phase 2 / Phase 3 |
| Unknown | 18F-DCFPyL PET-CT Scan and Prostate Cancer NCT03852654 | Lida Jafari | Phase 2 / Phase 3 |
| Active Not Recruiting | Prostate Oncologic Therapy While Ensuring Neurovascular Conservation (POTEN-C) NCT03525262 | University of Texas Southwestern Medical Center | Phase 2 |
| Unknown | Stereotactic Hypofractionated Accelerated Radiotherapy Post-Prostatectomy NCT02976402 | Fundacao Champalimaud | Phase 1 |
| Completed | Hypofractionated Focal Lesion Ablative Microboost in prostatE Cancer NCT02853110 | UMC Utrecht | Phase 2 |
| Completed | Multi-omics Analysis of Prostate Derived Extracellular Vesicles: an Observational Retrospective Study for Pros NCT07355985 | IRCCS San Raffaele | — |
| Completed | A Correlative Study of Biomarkers of Resistance in Patients With Castrate Resistant Prostate Cancer Treated Wi NCT01857908 | University Health Network, Toronto | — |
| Completed | Osteosclerotic Changes on CT Predict Survival in Prostate Cancer NCT06883474 | Sun Yat-sen University | — |
| Completed | Multiparametric Whole-Body MRI: a Game Changer in Metastatic Prostate Cancer NCT06827340 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |