| Not Yet Recruiting | Inavolisib for PIK3CA Mutated Advanced Endometrial Cancer: MITO END-4 Endometrial Cancer | Phase 2 | 2026-05-01 |
| Not Yet Recruiting | Cannabis extrAct in Oncology Patients for the Treatment of TUmor Related Symptom Burden Advanced Malignant Solid Tumor | Phase 2 | 2026-04-01 |
| Recruiting | Simvastatin Efficacy in ARID1A Mutated Advanced gastroESophageal Carcinoma Treated With Immunotherapy Advanced or Metastatic Gastrooesophageal Carcinoma | Phase 2 | 2026-03-13 |
| Recruiting | Pembrolizumab Plus Lenvatinib in Vulvar Cancer Patients: MITO VULVA-01 Vulva Cancer | Phase 2 | 2026-03-12 |
| Not Yet Recruiting | Using Artificial Intelligence to Guide Fluid Therapy During Major Cancer Surgery: A Randomized Controlled Tria Neoplasm, Cancer, Hemodynamic (MAP) Stability | N/A | 2026-02-01 |
| Not Yet Recruiting | Contribution of Oncovascular Surgery in the Treatment of Gynecological Advanced Malignant Diseases. Ovarian Carcinoma, Cervical Carcinoma, Endometrial Carcinoma | — | 2025-12-01 |
| Active Not Recruiting | REDI-CaP(Recovery of Erectile Dysfunction Induced in Prostate Cancer Patients) Prostate Cancer (Adenocarcinoma) | Phase 2 | 2025-12-01 |
| Recruiting | STREAM-2: Second-line Treatment With REgorafenib in Advanced RAS-Mutant Colorectal Cancer Colorectal Cancer Metastatic | Phase 2 | 2025-10-16 |
| Recruiting | Financial Toxicity in Patients With Early-stage Breast Cancer Breast Cancer | — | 2025-09-30 |
| Recruiting | Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal Locally Advanced Rectal Cancer (LARC) | — | 2025-09-01 |
| Recruiting | Application of da Vinci SP for Endometrial Cancer Surgical Staging Endometrial Cancer | — | 2025-04-03 |
| Recruiting | ValproIc Acid to Potentiate Anti-EGFR Treatment Efficacy and Prevent/Revert Resistance in Colorectal Cancer Colorectal Cancer Metastatic | Phase 2 | 2025-03-12 |
| Recruiting | Development of a Platform for the Clinical Implementation of Precision Oncology in the Central-Southern Region Neoplasm | — | 2024-12-10 |
| Recruiting | Spatial RadiomIcs and TRanscriptomics to the DIscovery of the Cross-link Between Colon Cancer and ChrOnic Kidn Colorectal Cancer (CRC) | — | 2024-11-05 |
| Recruiting | Multi-omic Approach to Cancer Diagnosis: the Italian Network of Excellence for Advanced Diagnosis (INNOVA) Neoplasms | — | 2024-10-08 |
| Recruiting | Effectiveness of Nurse Tele-consultation on the Quality of Elective Colonoscopy, Procedure-related Anxiety, an Patient Satisfaction and Efficacy of Bowel-preparation, Colon Cancer Prevention | N/A | 2024-06-24 |
| Recruiting | Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal C Colorectal Cancer Stage IV | Phase 3 | 2024-06-12 |
| Recruiting | Molecular-Based Selection of Patients with Head and Neck Squamous Cell Carcinoma: Biomarker Analysis Head and Neck Squamous Cell Carcinoma, Locally Advanced Stage | — | 2024-05-03 |
| Recruiting | PRO for Fighting FT in Ovarian Cancer Ovarian Cancer | — | 2023-10-30 |
| Recruiting | Identification of the Pathogenetic Mechanisms Underlying Squamous Cell Carcinomas Squamous Cell Carcinoma of the Head and Neck, Squamous Cell Carcinoma of the Anus | — | 2023-09-25 |
| Active Not Recruiting | The Study is Observational and Retrospective: Lifestyle, BMI and Activity Physical. Breast Cancer, Body Weight Change | — | 2023-09-04 |
| Recruiting | Neo-adjuvant Chemo and Immunotherapy in the Pre-operAtive Treatment of Locally Advanced CholangIOcarciNoma Cholangiocarcinoma | Phase 2 | 2023-09-01 |
| Recruiting | The ONCOCAMP Study Oncology | — | 2023-07-14 |
| Recruiting | Assessment of the Effectiveness of the Metabolomic Approach in Screening for Endometrial Cancer Endometrial Carcinoma (EC) | — | 2023-07-06 |
| Recruiting | Valproic Acid/Simvastatin Plus Gemcitabine/Nab-paclitaxel Based Regimens in Untreated Metastatic Pancreatic Ad Adenocarcinoma of the Pancreas | Phase 2 | 2023-06-12 |
| Unknown | Prediction of True Oligo-metastatic Disease. Oligometastatic Disease | — | 2023-01-17 |
| Recruiting | Tumor Antigen Discovery for Innovative Cancer Immunotherapies in HCC: from Benchside to Bedside (HepAnt) Hepatocellular Carcinoma | — | 2023-01-02 |
| Active Not Recruiting | A Phase I Trial of IMA970A Plus Montanide in Combination With Durvalumab (Anti-PD-L1) Hepatocellular Carcinoma | Phase 1 | 2022-11-22 |
| Recruiting | Selenoproteins as Prognostic Markers and Therapeutic Targets in Breast Cancer. Breast Cancer | — | 2022-05-19 |
| Recruiting | MITO 35B: Olaparib Beyond Progression Compared to Platinum Chemotherapy After Secondary Cytoreductive Surgery Ovarian Cancer | Phase 3 | 2022-01-21 |
| Unknown | MITO 35a: Olaparib Maintenance Therapy in Newly Diagnosed BRCA Wild-type Advanced Ovarian, Fallopian Tube and Ovarian Cancer | Phase 2 | 2021-12-09 |
| Recruiting | PRELUDE-1 (Prospective Evaluation of Radiotherapy-induced Biologic Effects in Colorectal Cancer Oligometastati Colorectal Cancer Metastatic | N/A | 2021-10-06 |
| Recruiting | Pain ASsessment in CAncer Patients by Machine LEarning (PASCALE) Oncology, Cancer Pain, Quality of Life | — | 2021-06-21 |
| Unknown | Molecular Data and Their Correlations With Clinical Outcomes in Gynecological Cancer Patients. Gynecologic Cancer | — | 2021-06-16 |
| Recruiting | A Trial Evaluating the Activity and Safety of Combination Between Cabozantinib and Temozolomide in Lung and GE Lung Neuroendocrine Neoplasm, GEP Neuroendocrine Tumor | Phase 2 | 2021-06-15 |
| Unknown | Impact of O6-methylguanine-DNA Methyltransferase (MGMT) Promoter Methylation and MGMT Expression on Dacarbazin Sarcoma | — | 2021-01-20 |
| Active Not Recruiting | "Principle Test" for Isolation and Characterization of Circulating Cancer Cells (CTC)-CXCR4+. Neoplasm Malignant | N/A | 2021-01-18 |
| Completed | MAnagement of METastatic Disease in Campania (MAMETIC) Metastatic Disease | — | 2020-09-11 |
| Unknown | Aflibercept or Bevacizumab as Second-line Treatment of RAS Mutated Metastatic Colorectal Cancer Metastatic Colorectal Cancer | — | 2020-05-11 |
| Unknown | Tocilizumab in COVID-19 Pneumonia (TOCIVID-19) COVID-19 Pneumonia | Phase 2 | 2020-03-19 |
| Completed | Multidisciplinary Integrated Platform for a Technological Innvovative Approach to Oncotherapies Biologic | — | 2020-03-02 |
| Recruiting | Study on Gynecological Rare Cancers Gynecologic Cancer | — | 2019-10-14 |
| Recruiting | Study of Folfiri/Cetuximab in FcGammaRIIIa V/V Stage IV Colorectal Cancer Patients Colorectal Cancer, ADCC | Phase 2 | 2019-09-05 |
| Unknown | Docetaxel or Hormone Therapy as Second Line Treatment in Patients With Asymptomatic or Oligosymptomatic Metast Metastatic Castration-resistent Prostate Cancer | Phase 3 | 2019-09-01 |
| Unknown | Olaparib in Patients With Recurrent Ovarian Cancer Wild Type for Germline and Somatic BRCA 1 and 2 Genes: The BRCA Wild Type Platinum Sensitive Recurrent Ovarian Cancer | Phase 2 | 2019-07-04 |
| Unknown | Valproic Acid in Combination With Bevacizumab and Oxaliplatin/Fluoropyrimidine Regimens in Patients With Ras-m Ras-mutated Metastatic Colorectal Cancer | Phase 2 | 2019-05-24 |
| Unknown | Active Surveillance Versus Surgery in Thyroid Papillary Microcarcinoma Papillary Microcarcinoma of the Thyroid | N/A | 2019-01-23 |
| Unknown | A Study Comparing Immunotherapy With Chemotherapy in the Treatment of Elderly Patients With Advanced NSCLC (MI Carcinoma, Non-Small-Cell Lung | Phase 2 | 2018-12-20 |
| Unknown | Validation of the Italian Version of the PRO-CTCAE Malignant Neoplasms | — | 2018-07-01 |
| Completed | Preoperative Nivolumab in Patients With Locally Advanced Colon Cancer (T3 or T4): a Window-of-opportunity Stud Colon Cancer Stage II/III | Phase 2 | 2018-06-12 |
| Completed | Intermittent or Continuous Panitumumab Plus FOLFIRI for RAS/B-RAF Wild-type Metastatic Colorectal Cancer Colorectal Cancer Stage IV | Phase 2 | 2018-05-21 |
| Unknown | Carboplatin, Paclitaxel With or Without Avelumab in Advanced or Recurrent Endometrial Cancer Endometrial Cancer | Phase 2 | 2018-04-01 |
| Unknown | Pembrolizumab With Chemotherapy in Front Line Advanced Ovarian, Primary Peritoneal and Fallopian Tube Cancer Ovarian Cancer | Phase 2 | 2018-04-01 |
| Unknown | Development and Validation of a Tool for Patient-reported Assessment of Cancer-related Financial Toxicity in I Cancer | — | 2018-03-01 |
| Unknown | REINFORCEMENT ANASTOMOSIS WITH Modified Cyanacrylate IN Patients Undergoing to Oncologic Colorectal Surgery Wi Colorectal Cancer | — | 2017-11-02 |
| Completed | IMA970A Plus CV8102 in Very Early, Early and Intermediate Stage Hepatocellular Carcinoma Patients Hepatocellular Carcinoma | Phase 1 / Phase 2 | 2017-09-18 |
| Completed | Octreotide LAR in the Induction of Immunologic Response in NENs Patients Neuroendocrine Tumors | Phase 2 | 2017-06-28 |
| Completed | Temozolomide for Second-Line Treatment of Neuroendocrine Carcinomas Neuroendocrine Carcinomas | Phase 2 | 2017-01-29 |
| Completed | Nivolumab in mRCC Patients: Treg Function, T-cell Access and NK Interactions to Predict and Improve Efficacy RCC, Metastatic Renal Cell Carcinoma | — | 2016-12-01 |
| Unknown | Diet, Exercise and Vitamin D in Breast Cancer Recurrence Breast Cancer | Phase 3 | 2016-11-04 |
| Unknown | Study Comparing Bevacizumab + Erlotinib vs Erlotinib Alone as First Line Treatment of Patients With EGFR Mutat Non-squamous Non-small Cell Lung Cancer | Phase 3 | 2016-04-01 |
| Unknown | Regorafenib Monotherapy as Second-line Treatment of Patients With RAS-mutant Advanced Colorectal Cancer Advanced Colorectal Cancer | Phase 2 | 2015-11-01 |
| Unknown | Endometrial Cancer Conservative Treatment (E.C.Co). A Multicentre Archive Endometrial Cancer | — | 2015-09-15 |
| Unknown | Valproic Acid Plus Cisplatin and Cetuximab in Recurrent and/or Metastatic Squamous Cell Carcinoma of Head and Squamous Cell Carcinoma of the Head and Neck | Phase 2 | 2015-02-23 |
| Unknown | A Phase II Prospective, Single Blinded, Randomized Trial of Hemopatch Compared to Standard Techniques to Achie Thoracic Surgery Lung, Post-operative Thoracic Air Leak | Phase 2 | 2015-02-01 |
| Unknown | Observational Retrospective Study on Treatment and Outcomes in Patients With Low-grade Serous Ovarian Cancer Low-grade Serous Ovarian Carcinoma, Recurrent Invasive Borderline Serous Ovarian Cancer | — | 2014-10-01 |
| Unknown | PET/CT Scan as a Tool to Rationalize the Treatment of Patients With Advanced ColoRectal Cancer Undergoing Firs Colorectal Cancer Stage IV | N/A | 2014-04-01 |
| Unknown | Bevacizumab Beyond Progression in Platinum Sensitive Ovarian Cancer Recurrent Ovarian Cancer | Phase 3 | 2013-11-01 |
| Unknown | PET/CT Scan as a Tool to Rationalize the Treatment of of Advanced NSCLC Patients Undergoing First Chemotherapy Non-small Cell Lung Cancer Metastatic, Non-small Cell Lung Cancer Stage IIIB | N/A | 2013-10-01 |
| Terminated | Systemic Therapy With or Without Upfront Transarterial Embolization for Inoperable Liver Metastasis of Neuroen Neuroendocrine Tumors | Phase 3 | 2013-07-01 |
| Unknown | A Phase 2 Study of Panitumumab in Patients With Cetuximab-refractory Metastatic Colorectal Cancer Metastatic Colorectal Cancer | Phase 2 | 2012-12-01 |
| Unknown | Study of Clinical and Biological Prognostic Factors in Patients With Ovarian Cancer Receiving Carboplatin +Pac Ovarian Cancer | Phase 4 | 2012-10-01 |
| Unknown | MILES-4: Study Comparing Gemcitabine and Pemetrexed, With or Without Cisplatin, in Patients With Nonsquamous L Non-small Cell Lung Cancer Metastatic, Non-small Cell Lung Cancer Stage IIIB | Phase 3 | 2012-08-01 |
| Unknown | Preoperative Valproic Acid and Radiation Therapy for Rectal Cancer Colorectal Cancer | Phase 1 / Phase 2 | 2012-05-01 |
| Completed | Optimization of Bevacizumab Scheduling With Chemotherapy for Metastatic Colorectal Cancer Colorectal Cancer | Phase 3 | 2012-05-01 |
| Unknown | Second Look Laparoscopy in Colorectal Cancer Colorectal Cancer | Phase 2 | 2012-04-01 |
| Unknown | Liposomal Cytarabine in the Treatment of Central Nervous System Resistant or Relapsed Acute Lymphoblastic Leuk Acute Lymphoblastic Leukemia | Phase 2 | 2012-03-01 |
| Unknown | Observational Study of Incidence of Breakthrough Cancer Pain and How it is Treated Advanced Cancer | — | 2011-12-01 |
| Unknown | Comparison of Bowel Cleansing Regimens Prior to Colonoscopy Patients Undergoing Elective Colonoscopy | Phase 4 | 2011-11-01 |
| Terminated | Sorafenib in First-line Treatment of Advanced B Child Hepatocellular Carcinoma Advanced Adult Hepatocellular Carcinoma | Phase 3 | 2011-07-01 |
| Unknown | MILES-3: Cisplatin in Combination With Gemcitabine for Elderly Patients With Lung Cancer Non-small Cell Lung Cancer Metastatic, Non-small Cell Lung Cancer Stage IIIB | Phase 3 | 2011-03-01 |
| Unknown | Multicenter Cohort Prospective Study on Multidisciplinary Treatment of Rectal Cancer Metastatic Colorectal Cancer | — | 2011-01-01 |
| Completed | Weekly Paclitaxel With or Without Pazopanib in Platinum Resistant or Refractory Ovarian Cancer Ovarian Cancer | Phase 2 | 2010-12-01 |
| Unknown | Observational Study on Treatment of Metastatic Colorectal Cancer and the Role of K-Ras Metastatic Colorectal Cancer | — | 2010-10-01 |
| Unknown | Pathway to Diagnosis of Ovarian Cancer Ovarian Cancer | — | 2010-01-01 |
| Completed | Predictive Factors of Clinical, Laboratory and Imaging Findings Routinely Used in Diagnosing Thyroid Cancer Thyroid Cancer | — | 2010-01-01 |
| Withdrawn | ELBA: Exemestane and Lapatinib in Advanced Breast Cancer Breast Cancer | Phase 2 | 2009-12-01 |
| Unknown | Study of Adding Cetuximab to Chemotherapy for the Treatment of Advanced and/or Recurrent Cervical Cancer Cervical Cancer | Phase 2 | 2009-10-01 |
| Unknown | Safety and Activity Study of Intrathecally Administered Ziconotide for Neuropathic Pain in Patients With Cance Pain, Neuropathic Pain, Intractable Pain | Phase 2 | 2009-09-01 |
| Unknown | Study Comparing Weekly Versus Every 3 Week Chemotherapy in Patients With Ovarian Cancer Ovarian Cancer | Phase 3 | 2008-11-01 |
| Unknown | Efficacy Study of Chemotherapy to Treat Ovarian Cancer Recurrence by Prolonging the Platinum Free Interval Ovarian Cancer | Phase 3 | 2008-11-01 |
| Terminated | CAPPA-2: Cisplatin Added to Gemcitabine in Poor Performance Advanced NSCLC Patients Non-Small Cell Lung Cancer | Phase 3 | 2007-11-01 |
| Unknown | VinCaT: Vinorelbine, Carboplatin and Trastuzumab in Advanced Her-2 Positive Breast Cancer Metastatic Breast Cancer | Phase 2 | 2007-10-01 |
| Withdrawn | CETRA: Neoadjuvant Caelyx and Trastuzumab in Her-2 Positive Breast Cancer Breast Cancer | Phase 2 | 2007-09-01 |
| Unknown | STAD-1 Small Cell Lung Cancer Toxicity Adjusted Dosing Study Small Cell Lung Cancer | Phase 3 | 2007-09-01 |
| Completed | Bevacizumab With Pelvic Radiotherapy And Primary Chemotherapy in Patients With Poor-Risk Rectal Cancer Rectal Cancer | Phase 2 | 2006-12-01 |
| Completed | TORCH: A Study of Tarceva or Chemotherapy for the Treatment of Advanced Non Small Cell Lung Cancer Advanced Non-Small Cell Lung Cancer | Phase 3 | 2006-12-01 |
| Completed | ZANTE: Zometa and Taxotere in Hormone Refractory Prostate Cancer Metastatic Prostate Cancer | Phase 1 | 2006-07-01 |
| Completed | MITO-6: Capecitabine in Platinum Resistant Ovarian Cancer Ovarian Cancer | Phase 2 | 2006-03-01 |
| Completed | CALC-1 (Cetuximab in Advanced Lung Cancer): Study of 2 Methods of Combining Cetuximab and Gemcitabine in Patie Advanced Non-Small Cell Lung Cancer | Phase 2 | 2005-11-01 |
| Terminated | The DISTAL-2 Study: Docetaxel Alone or in Combination in Second-line Treatment of Advanced Non Small-Cell Lung Advanced Non-Small Cell Lung Cancer | Phase 3 | 2005-05-01 |
| Unknown | HOBOE: A Phase 3 Study of Adjuvant Triptorelin and Tamoxifen, Letrozole, or Letrozole and Zoledronic Acid in P Breast Cancer | Phase 3 | 2004-03-01 |
| Completed | BREAST-10: Three-weekly Versus Weekly First-line Chemotherapy for Metastatic or Locally Advanced Breast Cancer Breast Cancer | Phase 3 | 2004-02-01 |
| Completed | ELDA: Elderly Breast Cancer - Docetaxel in Adjuvant Treatment Breast Cancer | Phase 3 | 2003-07-01 |
| Completed | MITO-5: Weekly Carboplatin and Paclitaxel as First Line Chemotherapy for Elderly Patients With Ovarian Cancer Ovarian Cancer | Phase 2 | 2003-06-01 |
| Completed | Study of Rofecoxib and Prolonged Constant Infusion of Gemcitabine in the Polychemotherapy Treatment of Advance Advanced Non-small Cell Lung Cancer | Phase 2 / Phase 3 | 2003-01-01 |
| Unknown | MITO-2: A Study Comparing 2 Chemotherapy Regimens (Carboplatin/Liposomal Doxorubicin vs Carboplatin/Paclitaxel Ovarian Cancer | Phase 3 | 2003-01-01 |
| Completed | END-1: First Line Chemotherapy for Advanced or Recurrent Endometrial Carcinoma With Carboplatin and Liposomal Endometrial Cancer | Phase 2 | 2002-11-01 |
| Completed | HERVIN: Trastuzumab and Vinorelbine in Metastatic Breast Cancer Metastatic Breast Cancer | Phase 2 | 2002-11-01 |
| Completed | MILES-02: Study of Chemotherapy Treatment and Toxicity in Elderly Patients With Advanced Non Small Cell Lung C Non Small Cell Lung Cancer | Phase 2 | 2002-06-01 |
| Completed | Fotemustine and Dacarbazine Versus Dacarbazine +/- Alpha Interferon in Advanced Malignant Melanoma Malignant Melanoma, Recurrent Melanoma | Phase 3 | 2002-04-01 |
| Completed | G-Step: Gemcitabine Based Small-cell Lung Cancer Treatment in Elderly Patients Small Cell Lung Cancer | Phase 1 / Phase 2 | 2000-11-01 |