Clinical Trials Directory

Trials / Unknown

UnknownNCT05233982

MITO 35a: Olaparib Maintenance Therapy in Newly Diagnosed BRCA Wild-type Advanced Ovarian, Fallopian Tube and Primitive Peritoneal Cancer

MITO 35a: A Multicenter, Prospective, Single Arm Trial of Olaparib Maintenance Therapy in Newly Diagnosed BRCA Wildtype Advanced Ovarian, Fallopian Tube and Primitive Peritoneal Cancer

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
200 (estimated)
Sponsor
National Cancer Institute, Naples · Academic / Other
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

This trial is a multicenter, prospective, phase II single arm, open-label trial in which patients with newly diagnosed advanced epithelial ovarian, primitive peritoneal, and fallopian tube cancer BRCA wild type, in partial or complete response to first line platinum-based chemotherapy, receive Olaparib maintenance therapy (300 mg, tablets formulation twice daily).

Conditions

Interventions

TypeNameDescription
DRUGOlaparib Oral ProductOlaparib Maintenace Treatment after first line platium based chemotherapy in BRCA wilde-type ovarian cancer patients

Timeline

Start date
2021-12-09
Primary completion
2026-01-01
Completion
2026-01-01
First posted
2022-02-10
Last updated
2023-03-24

Locations

5 sites across 1 country: Italy

Source: ClinicalTrials.gov record NCT05233982. Inclusion in this directory is not an endorsement.