NCT03380858

REINFORCEMENT ANASTOMOSIS WITH Modified Cyanacrylate IN Patients Undergoing to Oncologic Colorectal Surgery With Colorectal Anastomosis

REINFORCEMENT ANASTOMOSIS IN ONCOLOGIC COLORECTAL SURGERY

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 390 (estimated)
• Sponsor: National Cancer Institute, Naples · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

In colorectal surgery about 30% of postoperative mortality is attributed to anastomotic leak, whit an incidence range between 1.8% and 15.9%. Preventing the anastomotic leak can therefore bring benefits to the patient and the health system. To date we have technologically advanced suturizers and the correct realization (well-vascularized margins, not in tension, etc.) remains crucial to prevent anastomotic dehiscence. Experimental results demonstrate that modified cyanacrylate is a suitable potential "reinforcement" on intestinal anastomoses (manual or linear intra-corporeal). Applied after mechanical anastomosis, it polymerizes in a short time, closing the spaces of the suture line between one point and the other, expressing an adhesive, hemostatic and sealing action on the tissues, also creating an effective antiseptic barrier towards of the most common infectious or pathogenic agents.

Conditions

• Colorectal Cancer

Interventions

Type	Name	Description
DEVICE	colectomy	colectomy resection

Timeline

• Start date: 2017-11-02
• Primary completion: 2017-12-02
• Completion: 2019-05-02
• First posted: 2017-12-21
• Last updated: 2018-01-16

Locations

1 site across 1 country: Italy