Clinical Trials Directory

Trials / Conditions / Polycythemia Vera

Polycythemia Vera

141 registered clinical trials studyying Polycythemia Vera30 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingENERGIA: Personalized Exercise Program for Fatigue in Patients With Myeloproliferative Neoplasms and Chronic M
NCT07518940
Carmen FavaN/A
Not Yet RecruitingA Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)
NCT07429266
Ono Pharmaceutical Co., Ltd.Phase 3
Not Yet RecruitingEfficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Polycythemia Vera
NCT06290765
PharmaEssentiaPhase 4
RecruitingA ELN-Multicenter Study on Phenotypic Evolution and Clinical Outcomes
NCT07203768
FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
RecruitingMPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People
NCT07362225
MPN Research Foundation
RecruitingA Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)
NCT06661915
National Cancer Institute (NCI)Phase 2
Not Yet RecruitingStudy of BEBT-507 Injection in Subjects With Polycythemia Vera (PV)
NCT07012109
BeBetter Med IncPhase 1
Not Yet RecruitingPrevalence Of Germline Gene Mutations In Patients With Myeloproliferative Neoplasms With Family History
NCT06923670
Fondazione Policlinico Universitario Agostino Gemelli IRCCSN/A
Not Yet RecruitingEVAluation of Erythrocytosis PRospEctive Cohort STudy
NCT06785870
Cyrus Hsia
RecruitingRopeginterferon Alfa-2b in Patients With Polycythemia Vera (PV) Without Symptomatic Splenomegaly
NCT06743035
iOMEDICO AG
RecruitingLOW-PV Continuation
NCT06752941
FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
RecruitingEfficacy and Safety of Peginterferon in ET and PV.
NCT06734637
Zhenya HongN/A
Not Yet RecruitingReal-world Ruxolitinib Experience in PV
NCT06251102
Gruppo Italiano Malattie EMatologiche dell'Adulto
RecruitingFunctional and Phenotypic Characterization of Monocytes in Myeloproliferative Syndromes
NCT06361641
University Hospital, AngersN/A
RecruitingA Study of GLB-001 in Patients With Myeloid Malignancies
NCT06378437
Hangzhou GluBio Pharmaceutical Co., Ltd.Phase 1
RecruitingA Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)
NCT06351631
Merck Sharp & Dohme LLCPhase 3
RecruitingPacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition
NCT06218628
Fox Chase Cancer CenterPhase 1
RecruitingStudy on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera
NCT06093672
ItalfarmacoPhase 3
RecruitingA Study of Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of 9MW3011 in Patients
NCT06752746
Mabwell (Shanghai) Bioscience Co., Ltd.Phase 1
RecruitingCurcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance,
NCT06063486
University of Southern CaliforniaPhase 2
Active Not RecruitingStudy to Evaluate the Long-term Safety of Rusfertide (PTG-300) in Subjects With Polycythemia Vera
NCT06033586
Protagonist Therapeutics, Inc.Phase 3
CompletedA Study of Bomedemstat (MK-3543) in Participants With Polycythemia Vera (MK-3543-004)
NCT05558696
Imago BioSciences, Inc., a subsidiary of Merck & Co., Inc., (Rahway, New Jersey USA)Phase 2
TerminatedEvaluation of HU-resistance in Adult Patients With Polycythemia Vera Who Meet PV-AIM Predictors
NCT05853458
Novartis PharmaceuticalsPhase 4
RecruitingPegylated Interferon α-2b in Combination With Ruxolitinib for Treating Hydroxyurea-resistant/Intolerant PV
NCT05870475
Institute of Hematology & Blood Diseases Hospital, ChinaPhase 2
RecruitingAsian Myeloproliferative Neoplasm (MPN) Registry
NCT05882773
The University of Hong Kong
Active Not RecruitingStudy to Identify and Describe Predictive Factors for Thromboembolic Events in Patients With High-risk Polycyt
NCT05548062
Novartis Pharmaceuticals
Active Not RecruitingStudy to Assess SLN124 in Patients With Polycythemia Vera
NCT05499013
Silence Therapeutics plcPhase 1 / Phase 2
UnknownHematocrit to Hemoglobin Ratio and Red Blood Cell Distribution Width in Polycythemia Vera and Secondary Erythr
NCT05993065
Sohag University
Active Not RecruitingA Study to Assess Efficacy, Safety, and Tolerability of P1101 in Adult Patients With PV
NCT05481151
PharmaEssentiaPhase 3
UnknownChanges in QoL and Symptoms in Patients With Polycythemia Vera Receiving Ruxo in a Routine Clinical Practice
NCT05566535
Multinational Center for Quality of Life Research, Russia
Active Not RecruitingObservational Study on the Use of Ropeginterferon Alfa-2b in Polycythemia Vera (ROPEG-PV)
NCT06506084
FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
UnknownSafety Evaluation Study for Patients With Polycythemia Vera
NCT05074550
Perseus Proteomics Inc.Phase 1
RecruitingAVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V61
NCT05198960
University Hospital, BrestPhase 3
Active Not RecruitingA Phase 3 Study of Rusfertide in Patients With Polycythemia Vera
NCT05210790
Protagonist Therapeutics, Inc.Phase 3
RecruitingRuxolitinib in Thrombocythemia and Polycythemia Vera
NCT04644211
Massachusetts General HospitalPhase 2
RecruitingAn Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms
NCT05123365
University of California, IrvinePhase 1 / Phase 2
RecruitingTwo Step Haplo With Radiation Conditioning
NCT05031897
Thomas Jefferson UniversityPhase 2
Active Not RecruitingA Study to Access Efficacy and Safety of P1101 in Chinese PV Patients Who Are Intolerant or Resistance to HU
NCT05485948
PharmaEssentiaPhase 2
CompletedTo Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With P
NCT04629508
Incyte CorporationPhase 2
WithdrawnA Study of LNK01002 in Patients With Primary or Secondary Myelofibrosis,Polycythemia Vera or Acute Myeloid Leu
NCT04896112
Lynk Pharmaceuticals Co., LtdPhase 1
CompletedPTG-300 in Patients With Polycythemia Vera and Elevated Hematocrit
NCT04767802
Protagonist Therapeutics, Inc.Phase 2
Active Not RecruitingIMG-7289 in Patients With Essential Thrombocythemia (ET) or Polycythemia Vera (PV)
NCT04262141
Terrence J Bradley, MDPhase 2
RecruitingDecitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloprolif
NCT04282187
University of WashingtonPhase 2
RecruitingMITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia
NCT04116502
University of BirminghamPhase 3
CompletedHepcidin Mimetic in Patients With Polycythemia Vera (REVIVE)
NCT04057040
Protagonist Therapeutics, Inc.Phase 2
CompletedDual Vaccine Trial in Myeloproliferative Neoplasms
NCT04051307
Inge Marie SvanePhase 1 / Phase 2
TerminatedCPAP in Treating Obstructive Sleep Apnea in Patients With Polycythemia Vera or Essential Thrombocythemia
NCT03972943
University of UtahEARLY_Phase 1
Active Not RecruitingAzacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
NCT03862157
M.D. Anderson Cancer CenterPhase 1 / Phase 2
CompletedTesting the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myelop
NCT03878199
Ohio State University Comprehensive Cancer CenterPhase 1 / Phase 2
UnknownKRT-232 Compared to Ruxolitinib in Patients With Phlebotomy-Dependent Polycythemia Vera
NCT03669965
Kartos Therapeutics, Inc.Phase 2
CompletedClinical and Laboratory Characteristics of Polycythemia Vera
NCT06134102
IRCCS Azienda Ospedaliero-Universitaria di Bologna
CompletedThe NUTRIENT Trial (NUTRitional Intervention Among myEloproliferative Neoplasms): Feasibility Phase
NCT03907436
University of California, IrvineN/A
Active Not RecruitingTopotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Diso
NCT03289910
National Cancer Institute (NCI)Phase 2
CompletedSecondary Cancers in Myeloproliferative Neoplasms (MPN-K Study)
NCT03745378
FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
TerminatedA Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Idasanutlin Monotherapy in
NCT03287245
Hoffmann-La RochePhase 2
TerminatedFludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Pa
NCT03333486
Roswell Park Cancer InstitutePhase 2
CompletedPD-1 Inhibition in Advanced Myeloproliferative Neoplasms
NCT03065400
John MascarenhasPhase 2
Terminated18F-FLT (PET/CT) in Pediatrics With Myeloproliferative Neoplasms
NCT03121599
Hamad Medical CorporationN/A
CompletedEndoplasmic Reticulum Stress and Resistance to Treatments in Ph-negative Myeloproliferative Neoplasms
NCT02823184
University Hospital, Bordeaux
CompletedUltrasound Examination for Spleen Volume Evaluation in Myeloproliferative Neoplasms
NCT06371573
Federico II University
CompletedThe Benefit/Risk Profile of AOP2014 in Low-risk Patients With PV
NCT03003325
FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETSPhase 2
CompletedTreatment of Polycythaemia Vera and Essential Thrombocythaemia: Influence on the Clot Structure
NCT02912884
Dr Yan Beauverd
UnknownIncidence of Iron Deficiency in Polycythemia Vera (PV) and Association With Disease Features
NCT02809274
Rambam Health Care Campus
WithdrawnSiltuximab in Treating Patients With Primary, Post-Polycythemia Vera, or Post-Essential Thrombocythemia Myelof
NCT02805868
Northwestern UniversityEARLY_Phase 1
WithdrawnCell Cycle Regulatory Gene Study in Patients With Myeloproliferative Disorders
NCT02663648
Shandong University
CompletedShorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malig
NCT02556931
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsPhase 2
RecruitingMyeloproliferative Neoplastic Diseases Observatory From Brest
NCT02897297
University Hospital, Brest
CompletedA Prospective, Non-interventional Study of JAKAVI® (Ruxolitinib) Treatment in Patients With Polycythemia Vera
NCT05853445
Novartis Pharmaceuticals
CompletedStudy to Assess the Self-administration of AOP2014 Using a Pen, Developed for the Treatment of Polycythemia Ve
NCT02523638
AOP Orphan Pharmaceuticals AGPhase 3
CompletedTGR-1202 + Ruxolitinib PMF PPV-MF PET-MF MDS/MPN Polycythemia Vera Resistant to Hydroxyurea
NCT02493530
Vanderbilt-Ingram Cancer CenterPhase 1
CompletedOpen Label Study of Single Agent Oral RG7388 in Patients With Polycythemia Vera and Essential Thrombocythemia
NCT02407080
John MascarenhasPhase 1
RecruitingMyeloproliferative Neoplasms (MPNs) Patient Registry
NCT02760238
University Health Network, Toronto
CompletedSympathicomimetic Agonist in Patients With Myeloproliferative Neoplasms With JAK2-mutation
NCT02311569
Swiss Cancer InstitutePhase 2
Active Not RecruitingCINC424A2X01B Rollover Protocol
NCT02386800
Novartis PharmaceuticalsPhase 4
CompletedDrug Observance and Side Effects of Cytoreductive Drugs in PV and ET Patients
NCT02893410
University Hospital, Brest
CompletedExpanded Treatment Protocol (ETP) of Ruxolitinib in Patients With Polycythemia Vera Who Were Hydroxyurea Resis
NCT02292446
Novartis PharmaceuticalsPhase 3
CompletedAOP2014 vs. BAT in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study.
NCT02218047
AOP Orphan Pharmaceuticals AGPhase 3
CompletedAzacitidine and Sonidegib or Decitabine in Treating Patients With Myeloid Malignancies
NCT02129101
Mayo ClinicPhase 1
CompletedLong-term Safety and Efficacy of Momelotinib in Subjects With Primary Myelofibrosis, Post-polycythemia Vera My
NCT02124746
Sierra Oncology LLC - a GSK companyPhase 2
CompletedRuxolitinib Efficacy and Safety in Patients With HU Resistant or Intolerant Polycythemia Vera vs Best Availabl
NCT02038036
Novartis PharmaceuticalsPhase 3
TerminatedSafety and Efficacy of Momelotinib in Subjects With Polycythemia Vera or Essential Thrombocythemia
NCT01998828
Sierra Oncology LLC - a GSK companyPhase 2
CompletedA Phase 2 Study of RO7490677 In Participants With Myelofibrosis
NCT01981850
Hoffmann-La RochePhase 2
CompletedA Two-part Study to Assess the Safety and Preliminary Efficacy of Givinostat in Patients With Polycythemia Ver
NCT01901432
ItalfarmacoPhase 1 / Phase 2
CompletedPegylated Interferon Alpha-2b Versus Hydroxyurea in Polycythemia Vera
NCT01949805
AOP Orphan Pharmaceuticals AGPhase 3
CompletedA Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF
NCT01787552
Novartis PharmaceuticalsPhase 1 / Phase 2
CompletedMyeloproliferative Neoplasms: an In-depth Case-control Study
NCT01831635
Queen's University, Belfast
CompletedReduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic Malignancies
NCT01760655
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityPhase 2
CompletedVaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing
NCT01588015
City of Hope Medical CenterPhase 1
CompletedTissue Banking Study - Polycythemia Vera or Essential Thrombocythemia (PV & ET) Patients
NCT01970930
Icahn School of Medicine at Mount Sinai
CompletedStudy of LY2784544 Testing Alternative Dosing in Participants With Myeloproliferative Neoplasms
NCT01520220
Eli Lilly and CompanyPhase 1
CompletedRandomized Switch Study From Hydroxyurea to Ruxolitinib for RELIEF of Polycythemia Vera Symptoms: The Relief S
NCT01632904
Incyte CorporationPhase 3
UnknownMyeloproliferative Neoplasms and Bone Structure
NCT01816022
University of Southern Denmark
CompletedFludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem
NCT01529827
Roswell Park Cancer InstitutePhase 2
CompletedA Study of Low Dose Interferon Alpha Versus Hydroxyurea in Treatment of Chronic Myeloid Neoplasms
NCT01387763
Thomas Stauffer LarsenPhase 3
CompletedA Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies
NCT01384513
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityPhase 2
CompletedOpen Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycyth
NCT01243073
Geron CorporationPhase 2
Active Not RecruitingInfection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic
NCT01199562
City of Hope Medical Center
CompletedStudy of Efficacy and Safety in Polycythemia Vera Subjects Who Are Resistant to or Intolerant of Hydroxyurea:
NCT01243944
Incyte CorporationPhase 3
CompletedSafety Study of Pegylated Interferon Alpha 2b to Treat Polycythemia Vera
NCT01193699
AOP Orphan Pharmaceuticals AGPhase 1 / Phase 2
CompletedA Study in Myeloproliferative Disorders
NCT01134120
Eli Lilly and CompanyPhase 1
TerminatedArsenic Trioxide With or Without Ascorbic Acid in Treating Patients With Myelofibrosis
NCT01014546
Roswell Park Cancer InstitutePhase 1
CompletedMassage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Canc
NCT01053494
Wake Forest University Health SciencesN/A
TerminatedTrial of Erlotinib in Patients With JAK-2 V617F Positive Polycythemia Vera
NCT01038856
University of OklahomaPhase 2
CompletedSunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy
NCT00890747
National Cancer Institute (NCI)Phase 1
CompletedPomalidomide for Myelofibrosis Patients
NCT00946270
M.D. Anderson Cancer CenterPhase 2
UnknownNatural Killer Cells and Polycythemia Vera (Vaquez's Disease)
NCT01284712
Assistance Publique Hopitaux De Marseille
WithdrawnClopidogrel and Aspirin for the Treatment of Polycythemia Vera
NCT00940784
Ronald HoffmanPhase 2
CompletedPhase II Study of GIVINOSTAT (ITF2357) in Combination With Hydroxyurea in Polycythemia Vera
NCT00928707
ItalfarmacoPhase 2
UnknownA Study of the Efficacy of MK-0683 in Patients With Polycythaemia Vera and Essential Thrombocythaemia
NCT00866762
Copenhagen University Hospital at HerlevPhase 2
CompletedA Phase 1/2 Study of Oral SB1518 in Subjects With Chronic Idiopathic Myelofibrosis
NCT00745550
S*BIOPhase 1 / Phase 2
TerminatedLarge-scale Trial Testing the Intensity of CYTOreductive Therapy in Polycythemia Vera (PV)
NCT01645124
Consorzio Mario Negri SudPhase 3
UnknownCEP-701 (Lestaurtinib) in Myelofibrosis
NCT00668421
Ronald HoffmanPhase 1 / Phase 2
CompletedFamilial Myeloproliferative Disorders
NCT00666289
Icahn School of Medicine at Mount Sinai
CompletedVeliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leu
NCT00588991
National Cancer Institute (NCI)Phase 1
TerminatedA Phase 1 Study of XL019 in Adults With Polycythemia Vera
NCT00595829
ExelixisPhase 1
CompletedOpen-Label Study of Oral CEP-701 (Lestaurtinib) in Patients With Polycythemia Vera or Essential Thrombocytosis
NCT00586651
CephalonPhase 2
CompletedResearch Tissue Bank
NCT00666549
Icahn School of Medicine at Mount Sinai
TerminatedA Safety Study of XL019 in Adults With Myelofibrosis
NCT00522574
ExelixisPhase 1
CompletedOpen Label Ruxolitinib (INCB018424) in Patients With Myelofibrosis and Post Polycythemia Vera/Essential Thromb
NCT00509899
Incyte CorporationPhase 1 / Phase 2
TerminatedDasatinib in Polycythemia Vera
NCT00538980
Weill Medical College of Cornell UniversityPhase 2
CompletedCorrelative Biomarker Study in Patients With Myeloproliferative Disorders
NCT00665067
Icahn School of Medicine at Mount Sinai
CompletedMolecular Changes and Biomarkers in Chronic Myeloproliferative Disorders
NCT00433862
National Institutes of Health Clinical Center (CC)
CompletedEffects of Imatinib Mesylate in Polycythemia Vera
NCT00430066
Niguarda HospitalPhase 2
CompletedCyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis,
NCT00445744
Fred Hutchinson Cancer CenterN/A
Completed3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia,
NCT00381550
National Cancer Institute (NCI)Phase 2
CompletedPolycythemia Vera, Myelofibrosis and Essential Thrombocythemia: Identification of PV, MF & ET Genes
NCT00715247
University of Utah
CompletedVorinostat, Cytarabine, and Etoposide in Treating Patients With Relapsed and/or Refractory Acute Leukemia or M
NCT00357305
National Cancer Institute (NCI)Phase 1
CompletedFludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treati
NCT00397813
Fred Hutchinson Cancer CenterPhase 2
CompletedLenalidomide and Prednisone in Treating Patients With Myelofibrosis
NCT00227591
National Cancer Institute (NCI)Phase 2
CompletedDasatinib as Therapy for Myeloproliferative Disorders (MPDs)
NCT00255346
M.D. Anderson Cancer CenterPhase 2
CompletedEfficacy and Safety of Pegylated Interferon Alfa in Polycythemia Vera
NCT00241241
PV-NordPhase 2
CompletedTacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone To
NCT00089011
Fred Hutchinson Cancer CenterPhase 2
CompletedBiological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leuke
NCT00052520
Fred Hutchinson Cancer CenterPhase 1 / Phase 2
CompletedTreatment of Polycythemia Vera With Gleevec
NCT01120821
Weill Medical College of Cornell UniversityPhase 2
CompletedTipifarnib in Treating Patients With Myelofibrosis and Myeloid Metaplasia
NCT00047190
National Cancer Institute (NCI)Phase 2
CompletedImatinib Mesylate in Treating Patients With Myelofibrosis
NCT00039416
National Cancer Institute (NCI)Phase 2
CompletedImatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction
NCT00025415
National Cancer Institute (NCI)Phase 1
CompletedTherapy of HES, PV, Atypical Chronic Myelocytic Leukemia (CML) or Chronic Myelomonocytic Leukemia (CMML), and
NCT00038675
M.D. Anderson Cancer CenterN/A
CompletedFludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies
NCT01499147
University of Illinois at ChicagoN/A
CompletedFludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenola
NCT00112593
Fred Hutchinson Cancer CenterN/A
No Longer AvailableMAP to Provide Access to Ruxolitinib, for Patients With Polycythemia Vera
NCT05269771
Novartis Pharmaceuticals