NCT02897297

Myeloproliferative Neoplastic Diseases Observatory From Brest

Observatoire Brestois Des Néoplasies Myéloprolifératives

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: University Hospital, Brest · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

All patients diagnosed or followed in Brest University Hospital for Philadelphia negative myeloproliferative neoplasms will be included in this observational study. Myeloproliferative neoplasms recorded included: polycythemia vera, essential Thrombocythemia and Primary Myelofibrosis. This is a not interventional study. Alive patients need to sign a non-opposition consent form. Patients will be followed until last news (death, change of reference centre...).

Detailed description

In this retrospective and prospective study, clinical and biological data from diagnosis until last news will be recorded. Clinical data collected: patients and disease characteristics at the time of the diagnosis, disease and mutational status, cardio-vascular risk factors, history of thrombosis and cancer. Biological data collected: hemogram and bone marrow results if available. During the follow-up new data will be noted: treatment changes (reasons of change and type of drug), thrombotic events (localization, date and hemogram), phenotypic evolutions (type and date), death (date and etiology).

Conditions

• Polycythemia Vera
• Essential Thrombocythemia
• Primary Myelofibrosis

Timeline

• Start date: 2015-09-01
• Primary completion: 2025-09-30
• Completion: 2025-09-30
• First posted: 2016-09-13
• Last updated: 2024-08-12

Locations

1 site across 1 country: France