Trials / Conditions / Persistent Atrial Fibrillation

Persistent Atrial Fibrillation

199 registered clinical trials studyying Persistent Atrial Fibrillation — 46 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation NCT07382024	National Taiwan University Hospital	N/A
Not Yet Recruiting	PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fi NCT07324772	Northwestern University	N/A
Recruiting	Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Us NCT07298473	Medtronic Cardiac Ablation Solutions	N/A
Recruiting	REPRESENT-PF Registry NCT07535268	Vivek Reddy	—
Enrolling By Invitation	Catheter Ablation of Advanced Forms of Atrial Fibrillation NCT07446244	University Medical Centre Ljubljana	N/A
Not Yet Recruiting	Circumferential Pulmonary Venous Isolation Combined With Bachmann Bundle Modification Versus Circumferential P NCT07445360	Shenyang Northern Hospital	N/A
Not Yet Recruiting	Evaluation of the Efficacy of Pulmonary Vein Isolation by Pulsed-field Ablation in Persistent Atrial Fibrillat NCT06985901	Centre Hospitalier Universitaire de Nice	N/A
Not Yet Recruiting	PVI Alone Versus PVI Plus PWI and SVCI With PFA NCT07405359	Edward Gerstenfeld, MD	N/A
Recruiting	Evaluation of Novel Waveforms Delivered Using the FARAPULSE™ PFA System NCT07444320	Boston Scientific Corporation	N/A
Recruiting	Study on the Prevention of Atrial Fibrillation Recurrence After Ablation by Qidong Yixin Granule NCT07508618	Sir Run Run Shaw Hospital	Phase 4
Not Yet Recruiting	Renal Denervation Combined With Pulsed Field Ablation to Prevent Blanking-Period Recurrence in Persistent Atri NCT07320768	Shanghai Chest Hospital	N/A
Not Yet Recruiting	PFLotus With the DePolar Mapping System in Patients With Persistent Atrial Fibrillation NCT07321002	The Third People's Hospital of Chengdu	N/A
Recruiting	BaLloon-based PFA Ablation poST Approval Outcomes for PAF and PersAF NCT07181590	Abbott Medical Devices	N/A
Recruiting	Evaluation of Two Different Regimens of the Antiarrhythmic Drug Amiodarone to Maintain Normal Sinus Rhythm Aft NCT07273994	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	Phase 4
Recruiting	SPHERE Per-AF Post-Approval Study NCT06858306	Medtronic Cardiac Ablation Solutions	—
Recruiting	A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter NCT07116525	Biosense Webster, Inc.	N/A
Recruiting	PVI Alone vs PVI and Linear Ablation for Persistent Atrial Fibrillation (PROMPT AF II) NCT07106970	Boston Scientific Corporation	N/A
Recruiting	Optimized Ablation of the Posterior Wall in Persistent Atrial Fibrillation NCT07122336	Shanghai Chest Hospital	N/A
Not Yet Recruiting	Posterior Mitral Isthmus Line With Vein of Marshall Ethanolisation Compared With Anterior Mitral Lines in Pati NCT06962176	AZ Sint-Jan AV	N/A
Recruiting	Pulsed Field Ablation vs. Cryoballoon Ablation in Patients With Persistent Atrial Fibrillation NCT07064616	Kitasato University	N/A
Recruiting	FIH Study of PFLotus in Persistent Atrial Fibrillation NCT07301190	The Third People's Hospital of Chengdu	N/A
Recruiting	A Prospective Clinical Study to Evaluate the Safety and Effectiveness of Pulmonary Vein Isolation Plus Box Iso NCT06973031	Kardium Inc.	N/A
Recruiting	Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPU NCT06735534	Boston Scientific Corporation	N/A
Not Yet Recruiting	PFA-based Bi-atrial Maze-like Catheter Ablation for PeAF NCT06952023	The First Affiliated Hospital of Dalian Medical University	N/A
Active Not Recruiting	Pragmatic Evaluation of a Pentaspline Pulsed Field Ablation System to Treat Atrial Fibrillation and Related Ar NCT06765356	Vivek Reddy	Phase 4
Not Yet Recruiting	Study on the Ablation of Persistent Atrial Fibrillation Using Pulsed Electric Fields Under Different Surgical NCT06671197	Second Affiliated Hospital, School of Medicine, Zhejiang University	—
Recruiting	ARIADNE Clinical Trial NCT06747091	Stavros E Mountantonakis	N/A
Recruiting	Feasibility Study of the FARAFLEX Mapping and PFA System NCT06510556	Boston Scientific Corporation	N/A
Not Yet Recruiting	Pulsed Field Ablation Versus Radiofrequency Ablation for Persistent Atrial Fibrillation NCT06791629	Beijing Anzhen Hospital	N/A
Active Not Recruiting	Using a Novel Balloon-shaped Large-Focal Pulsed Field Ablation Catheter in Persistent Atrial Fibrillation NCT07294742	The Third People's Hospital of Chengdu	N/A
Not Yet Recruiting	Optimized Posterior Left Atrial Wall Ablation Strategy for PeAF NCT06633523	Shanghai Chest Hospital	N/A
Active Not Recruiting	EGM Guided PFA for PerAF NCT06729866	Xu Liu	N/A
Not Yet Recruiting	Rotor Modulation Ablation for the Treatment of Persistent Atrial Fibrillation NCT06539819	Zhujiang Hospital	N/A
Recruiting	Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation NCT06165510	Barts & The London NHS Trust	N/A
Recruiting	Investigation of Cardioversion Versus Therapeutic Ablation for Persistent AF (ORBICA-AF) NCT06096246	Barts & The London NHS Trust	N/A
Recruiting	Endocardial Mapping With the CoreMap EP Mapping System NCT06529978	CoreMap Inc.	N/A
Recruiting	VEin of MArshall Ethanolization Vs Extended Pulmonary Vein PULSEd Field Ablation After Failed PVI for Persiste NCT06383975	Sebastien Knecht	N/A
Not Yet Recruiting	Accelerated Pacing in Patients Undergoing Pace-and-ablate Strategy With LBBAP: a Randomized Controlled Pilot T NCT06377046	Maastricht University Medical Center	N/A
Withdrawn	Clinical Outcomes of Persistent Atrial Fibrillation Ablation Using Ablation Index-guided Radiofrequency Cathet NCT05406310	St. Louis University	—
Completed	Feasibility Study on the FARAVIEW Technology NCT06175234	Boston Scientific Corporation	N/A
Completed	VOLT-AF IDE Clinical Study NCT06223789	Abbott Medical Devices	N/A
Completed	A Dual Energy Catheter (PFA and RFA) and a PFA Catheter for the Treatment of PeAF NCT06232798	Shanghai MicroPort EP MedTech Co., Ltd.	N/A
Active Not Recruiting	Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atr NCT06096337	Boston Scientific Corporation	N/A
Recruiting	ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients NCT05988411	Vivek Reddy	N/A
Active Not Recruiting	Electroporation for Treatment of Atrial Fibrillation NCT06134752	University Medical Centre Ljubljana	N/A
Active Not Recruiting	The PIFPAF-PFA Study NCT05986526	Insel Gruppe AG, University Hospital Bern	N/A
Withdrawn	AcQBlate Force Sensing Ablation System US IDE Study for Atrial Fibrillation NCT04904354	Acutus Medical	N/A
Recruiting	VOLT CE Mark Study NCT06106594	Abbott Medical Devices	N/A
Recruiting	Observational Study to Examine the Procedural and Outcomes of AF Ablation Assisted by STAR Apollo™ Mapping Sys NCT05826665	Kansas City Heart Rhythm Research Foundation	—
Completed	A Study of Intracardiac Ultrasound With the NUVISION NAV Ultrasound Catheter NCT05970120	Biosense Webster, Inc.	N/A
Active Not Recruiting	Persistent Atrial Fibrillation Without the Evidence of Low-voltage Areas NCT06124690	Robert Bosch Medical Center	N/A
Terminated	The Study for Evaluate of Safety and Efficacy of Vein of Marshall RF Ablation NCT05854238	Tau-MEDICAL Co., Ltd.	N/A
Active Not Recruiting	Pulsed-field Ablation in Patients With Persistent Atrial Fibrillation NCT05922917	České Budějovice Hospital	N/A
Recruiting	EfFect of Ablation of Persistent AtriaL Fibrillation on COgNitive Function in Individuals With Mild Cognitive NCT05790707	Poitiers University Hospital	N/A
Recruiting	AV Junction Ablation or Optimal Medical Treatment in PatiEnts With Cardiac Resynchronization Therapy and Perma NCT05776797	University Hospital Ostrava	N/A
Unknown	PLAI-AF Trial: Hybrid Endo-epicardial Partial Left Atrial Isolation vs. Endocardial Ablation in Patients With NCT05723536	Hospital Clinic of Barcelona	Phase 3
Active Not Recruiting	Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal o NCT05462145	Kardium Inc.	N/A
Completed	A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects With Persi NCT05443594	Boston Scientific Corporation	N/A
Recruiting	Pulmonary Vein Isolation Alone or in Combination With Substrate Modulation After Electric Cardioversion Failur NCT05264831	Elsan	N/A
Withdrawn	Inflammatory and Endothelial Function Response, and Arrhythmia Recurrence Following Catheter Ablation for Atri NCT04269785	Karan Saraf	N/A
Unknown	Left Atrial Isolation by Catheter Ablation in Persistent Atrial Fibrillation With Severe Atrial Fibrosis NCT05173779	Shanghai Chest Hospital	N/A
Completed	PerAF: AF Termination vs Prespecified Ablation NCT06837441	Shanghai Chest Hospital	N/A
Unknown	Univu-guided Vein of Marshall Ethanol Infusion (Marshall-Merge) NCT05652517	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	N/A
Completed	Efficacy and Safety Evaluation of Refralon®, Concentrate for Solution for Intravenous Injection in Patients Wi NCT05773170	R-Pharm	—
Unknown	Combined Study of ATrial Strain and Voltage by High Density Mapping in Young Patients With Atrial Fibrillation NCT05565183	Assistance Publique - Hôpitaux de Paris	N/A
Withdrawn	Electrographic Flow Mapping Validation in Patients With Persistent Atrial Fibrillation (EVAL AF) NCT05093868	Corewell Health East	N/A
Completed	FLOW EVAL-AF: FLOW Mapping Electrogram VALidation in Patients With Persistent Atrial Fibrillation NCT06260670	Ablacon, Inc.	N/A
Unknown	CARTO-Finder Guided Ablation Versus Multiscale Entropy Guided Ablation in Persistent Atrial Fibrillation NCT05454111	Shanghai Chest Hospital	N/A
Completed	A Study Assessing Arrhythmia Mapping With a Globe-Shaped, High-Density, Multi-Electrode Mapping Catheter NCT05373862	Biosense Webster, Inc.	N/A
Completed	Single Center Pilot Study Using the ECGenius System to Collect Electrogram Data to Test an Ablation Impact Alg NCT05458648	CathVision ApS	—
Unknown	Personalized Persistent Atrial Fibrillation Ablation: The PeAF-by-LAWT Trial NCT05396534	Centro Medico Teknon	N/A
Recruiting	Hybrid Ablation of Atrial Fibrillation in Heart Failure NCT05411614	St. George's Hospital, London	N/A
Recruiting	Bi-atrial Versus Left Atrial Ablation for Patients With Rheumatic Mitral Valve Disease and Non-paroxysmal Atri NCT05021601	China National Center for Cardiovascular Diseases	N/A
Active Not Recruiting	Heart Rehabilitation for All NCT05104658	Center for Clinical Research and Prevention	N/A
Active Not Recruiting	Radial Ablation for the Control of Persistent Atrial Fibrillation NCT04662489	Fundacion para la Innovacion en Biomedicina (FIBMED)	N/A
Terminated	MultiPulse Therapy (MPT) for AF (US) NCT05055921	Cardialen, Inc.	N/A
Recruiting	Acute Responses to Exercise in Females and Males With Symptomatic Atrial Fibrillation NCT05085860	Ottawa Heart Institute Research Corporation	N/A
Completed	The FARAPULSE PersAFOne III Trial for the Treatment of Persistent Atrial Fibrillation NCT05272852	Boston Scientific Corporation	N/A
Completed	High-Power, Short-Duration Ablation in Treatment of Patients With Atrial Fibrillation NCT06415149	People's Friendship University of Russia	N/A
Unknown	Real-world Experience of Catheter Ablation Using Novel Ablation Technologies for the Treatment of Atrial Fibri NCT05006456	Beijing Anzhen Hospital	—
Unknown	Catgut Embedding in Acupoints on Treating Persistent Atrial Fibrillation After Catheter Ablation NCT05125042	Shanghai Chest Hospital	N/A
Unknown	Catheter Ablation and Surgical Ablation of Persistent Atrial Fibrillation With Severe Atrial Fibrosis NCT05153486	Shanghai Chest Hospital	N/A
Unknown	Patient-TAILORed Ablation of Persistent AF Guided by Instantaneous Amplitude and Frequency Modulation Maps (TA NCT05169320	Hospital San Carlos, Madrid	—
Unknown	Individualised Mapping in Persistent AF Ablation NCT05065112	Royal Brompton & Harefield NHS Foundation Trust	N/A
Completed	Adjunctive Right Atrial Ablation for Persistent Atrial Fibrillation With Right Atrial Enlargement NCT05227586	Shanghai Chest Hospital	—
Unknown	Driver Ablation of Persistent Atrial Fibrillation With Severe Atrial Fibrosis. NCT05085912	Shanghai Chest Hospital	N/A
Completed	Investigation of Therapeutic Ablation Versus Cardioversion for AF NCT03907982	Barts & The London NHS Trust	N/A
Completed	Feasibility Study of the FARAPULSE™ Cardiac Ablation System Plus in the Treatment of Persistent Atrial Fibrill NCT05152966	Boston Scientific Corporation	N/A
Completed	Automated Assessment of PVI Using a Novel EP Recording System NCT05043883	CathVision ApS	N/A
Terminated	iCLAS™ Cryoablation System Post-Market Clinical Follow-up (PMCF) Study NCT05416086	Adagio Medical	N/A
Withdrawn	WATCHMAN for Concomitant Left Atrial Appendage Electrical Isolation and Occlusion to Treat Persistent Atrial F NCT03835338	Boston Scientific Corporation	N/A
Unknown	Hybrid Characterization of Driver Sites During Atrial Fibrillation and Sinus Rhythm NCT05077670	Fundacion para la Innovacion en Biomedicina (FIBMED)	—
Completed	Comparison Between Upgraded '2C3L' vs. PVI Approach for Catheter Ablation of Persistent Atrial Fibrillation NCT04497376	Beijing Anzhen Hospital	N/A
Completed	A Study Assessing Arrhythmia Mapping With the Multi-Electrode OPTRELL™ Mapping Catheter NCT04983797	Biosense Webster, Inc.	N/A
Active Not Recruiting	STOP Persistent AF PAS NCT05005949	Medtronic Cardiac Ablation Solutions	—
Completed	Skin Sympathetic Nerve Activity and Cardiac Arrhythmia NCT04918303	University Hospital, Bordeaux	N/A
Unknown	Left Atrial Posterior Wall and PV Isolation Using Cryoballoon for Treatment of Persistent AF NCT04505163	Dignity Health Medical Foundation	N/A
Unknown	The RODEO Micro Mapping Catheter in Cryoablation Procedures NCT04845750	afreeze GmbH	N/A
Withdrawn	Comparison of Treatment Outcomes Between Convergent Procedure and Catheter Ablation for Persistent and Longsta NCT04509180	University Medical Centre Ljubljana	N/A
Active Not Recruiting	Optimal Ablation Strategies for Persistent AF With HF NCT07153718	Xu Liu	N/A
Unknown	Substrate Guided Ablation Therapy for Atrial Fibrillation NCT04657978	Royal Brompton & Harefield NHS Foundation Trust	—
Completed	Hybrid Ablation Plus Medical Therapy for Persistent Atrial Fibrillation NCT04190186	University of Rochester	N/A
Active Not Recruiting	Left Atrial Posterior Wall Additional Isolation for Persistent Atrial Fibrillation Trial NCT04405258	Institute for Clinical Effectiveness, Japan	Phase 4
Completed	AF Ablation for HF With Reduced EF NCT05827172	Shanghai Chest Hospital	N/A
Completed	Left Atrial Arrhythmia Substrate Identification After Confirmed durABLE Pulmonary Vein Isolation NCT04111731	Liverpool Heart and Chest Hospital NHS Foundation Trust	N/A
Terminated	Persistent Atrial Fibrillation (AF) APAC (Asia Pacific) Observational Study NCT04244396	Abbott Medical Devices	—
Completed	iCLAS™ for Persistent Atrial Fibrillation NCT04061603	Adagio Medical	N/A
Unknown	Cryoballoon Pulmonary Vein Isolation vs. Cryoballoon Pulmonary Vein Isolation With Additional Right Atrial Lin NCT03682887	Yonsei University	N/A
Completed	Feasibility Study of the FARAPULSE Endocardial Multi Ablation System in the Treatment of Persistent Atrial Fib NCT04170621	Boston Scientific Corporation	N/A
Unknown	Driver-guided Ablation of Persistent Atrial Fibrillatiom NCT04085731	IRCCS Policlinico S. Donato	—
Completed	HD Mapping of Atrial Fibrillation in Asia Pacific NCT04022954	Abbott Medical Devices	—
Completed	High-Density (HD) Wave Mapping in Subjects With Atrial Fibrillation as a Predictor of Recurrence After a Singl NCT03882021	Abbott Medical Devices	N/A
Completed	Reducing Recurrence of Symptomatic Atrial Fibrillation After Catheter Ablation by App-based Mental Training NCT04067427	Helios Health Institute GmbH	N/A
Completed	'Understanding the Electrophysiological Substrate Underlying Persistent Atrial Fibrillation Study II (USURP AF NCT04041778	University of Leicester	—
Completed	FIRE AND ICE II Trial Pilot NCT03706677	Medtronic Cardiac Rhythm and Heart Failure	N/A
Active Not Recruiting	AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment NCT03732794	AtriCure, Inc.	N/A
Unknown	Double Sequential External Defibrillation in Patients With Atrial Fibrillation Refractory to DC Cardioversion NCT03827915	American University of Beirut Medical Center	N/A
Unknown	Treatment Success With the CoolLoop Cryoablation System NCT03818724	afreeze GmbH	—
Completed	Advisor HD Grid Observational Study NCT03733392	Abbott Medical Devices	—
Recruiting	Medtronic Terminate AF Study NCT03546374	Medtronic Cardiac Surgery	N/A
Completed	Safety and Effectiveness of TactiCath™ Contact Force, Sensor Enabled™ (TactiCath SE) Catheter for Ablation of NCT03650556	Abbott Medical Devices	N/A
Completed	DiamondTemp™ System for the Treatment of Persistent Atrial Fibrillation NCT03643224	Medtronic Cardiac Ablation Solutions	N/A
Completed	Effects of Different Surgical Methods for Persistent Atrial Fibrillation Combined With the Application of Stat NCT03700307	The Second Hospital of Hebei Medical University	N/A
Completed	AF Septal Pacing (Clinical Investigation Plan) NCT03242941	Medtronic BRC	N/A
Terminated	Atrial Fibrillation Trial to Evade Recurrence: effectS of Hiit Before electrO-Cardioversion for 3-weeKs NCT03467633	Ottawa Heart Institute Research Corporation	N/A
Terminated	Model Based Fast Anatomical Mapping NCT03349476	Vivek Reddy	N/A
Completed	Effect of Catheter Ablation on Left Atrial Function in Persistent Atrial Fibrillation NCT03443232	The Second Hospital of Hebei Medical University	N/A
Unknown	Cryoballon Versus Radiofrequency Ablation for Persistent Atrial Fibrillation NCT03365700	Luigi Sacco University Hospital	N/A
Recruiting	Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation NCT04088071	Heart Rhythm Clinical and Research Solutions, LLC	—
Terminated	ECGi Ibutilide: Effect of Ibutilide on AF Source Location and Organization NCT03370536	Vivek Reddy	N/A
Unknown	Comparison of Two Pulmonary Vein Ablation Techniques for Persistent AF NCT03295422	Sequoia Hospital	N/A
Unknown	Ablation of Low Voltage Regions in Persistent Atrial Fibrillation NCT03811938	Imperial College London	N/A
Unknown	Left Atrial Function Analysis for Patients With Persistent Atrial Fibrillation Undergoing Pulmonary Vein Isola NCT03242694	Semmelweis University Heart and Vascular Center	—
Completed	RADAR Clinical Trial NCT03263702	Vivek Reddy	N/A
Unknown	Study Comparing Pulmonary Vein Isolation With the Cryoballoon and Radiofrequency Energy(Contact Force) in the NCT03053570	China Cardiometabolic Registries	N/A
Completed	Comparison of Pulmonary Vein Ablation With or Without Left Atrial Posterior Wall Ablation for Persistent AF (P NCT03057548	Arash Aryana, MD	N/A
Completed	Repetitive Activation Patterns and Focal Impulses Identification and Ablation in Persistent AF NCT03064451	Biosense Webster, Inc.	N/A
Completed	FIND CAN Trial: "CF-172" NCT03033641	Biosense Webster, Inc.	N/A
Unknown	One Staged Hybrid Approach of Surgical/Catheter Ablation for Persistent Atrial Fibrillation NCT02968056	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	N/A
Completed	Comparison Between One-stage Hybrid Ablation and Thoracoscopic Surgical Ablation for Intractable Atrial Fibril NCT03127423	China National Center for Cardiovascular Diseases	N/A
Unknown	Liner Ablation Using Contact-force in Atrial Fibrillation NCT03091972	Korea University Anam Hospital	N/A
Completed	Beat-to-beat Variability in Persistent Atrial Fibrillation NCT03092362	Heart and Diabetes Center North-Rhine Westfalia	—
Completed	Norwegian Study of Persistent Atrial Fibrillation Treatment: Cryoballoon Versus Radiofrequency Catheter Ablati NCT03008811	Haukeland University Hospital	N/A
Unknown	Remote Magnetic Navigation-guided Ablation Versus Cryoablation for Persistent Atrial Fibrillation (RECREATION NCT03044925	Ruijin Hospital	N/A
Completed	Utilizing Novel Dipole Density Capabilities to Objectively Visualize the Etiology of Rhythms in Atrial Fibrill NCT02825992	Acutus Medical	N/A
Completed	Evaluation of a Multi-electrode Linear Type Catheter (D-1368-01-SI) NCT02991313	Biosense Webster, Inc.	N/A
Unknown	Catheter Ablation Therapy for Persistent Atrial Fibrillation NCT02892162	China National Center for Cardiovascular Diseases	N/A
Completed	Electrical Cardioversion, Ablation or Pace and Ablate for Persistent Atrial Fibrillation NCT02528604	Eastbourne General Hospital	Phase 4
Completed	Epicardial Approach in Recurred Atrial Fibrillation NCT02979847	Korea University Anam Hospital	N/A
Withdrawn	Epicardial Mini-Maze Versus Catheter Ablation for the Management of Persistent Atrial Fibrillation NCT03446222	The University of Texas Health Science Center, Houston	N/A
Completed	Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation With FIRM Guided Procedures NCT02799043	Abbott Medical Devices	N/A
Terminated	The Substrate and Intervention Mechanisms for Persistent Atrial Fibrillation Trial NCT02918396	Johns Hopkins University	N/A
Completed	The Low Voltage Guided Ablation Trial of Persistent Atrial Fibrillation NCT02732626	Mödling Hospital	N/A
Completed	Oesophageal Pacing to Check Left Atrial Posterior Wall Isolation NCT05086861	University Hospital Plymouth NHS Trust	N/A
Withdrawn	PVI Using Cryoablation Alone in Paroxysmal AF Patients Converted From Persistent AF With Dofetilide NCT01877486	University of Rochester	—
Unknown	Atrial Fibrillation Ablation Compared to Rate Control Strategy in Patients With Impaired Left Ventricular Func NCT02509754	University of Turin, Italy	Phase 4
Unknown	Comparison of Brain Perfusion in Rhythm Control and Rate Control of Persistent Atrial Fibrillation NCT02633774	Yonsei University	N/A
Active Not Recruiting	Correlation of the Arrhythmia Mechanism and Substrate to Ablate Persistent Atrial Fibrillation Study NCT02184013	Ottawa Heart Institute Research Corporation	N/A
Completed	AF Substrate Mapping and Guided Ablation NCT02571218	Abbott Medical Devices	N/A
Unknown	Catheter Ablation Versus Thoracoscopic Surgical Ablation in Long Standing Persistent Atrial Fibrillation (CASA NCT02755688	Royal Brompton & Harefield NHS Foundation Trust	N/A
Completed	Calcium Handling and Epicardial Ablation NCT04174885	University of Campania Luigi Vanvitelli	N/A
Completed	Randomized Evaluation of Atrial Fibrillation Treatment With Focal Impulse and Rotor Modulation Guided Procedur NCT02274857	Abbott Medical Devices	N/A
Completed	Multimodal Image Processing Software to Guide Cardiac Ablation Therapy NCT02275104	University Hospital, Bordeaux	—
Withdrawn	Comparison of Hybrid Ablation and Pulmonary Vein Isolation Alone vs Hybrid Ablation With PVI Plus Catheter Abl NCT02344394	Wake Forest University Health Sciences	N/A
Unknown	Eagle AF (Atrial Fibrillation) - Endoscopically Guided Laser Ablation of Persistent Atrial Fibrillation NCT02234102	Prof. Dr. med. Bernd Lemke	N/A
Completed	A Feasibility Study to Evaluate the Effect of Concomitant Renal Denervation and Cardiac Ablation on AF Recurre NCT01907828	Abbott Medical Devices	N/A
Completed	Treatment of Atrial Fibrillation in Patients by Pulmonary Vein Isolation in Combination With Renal Denervation NCT02115100	Diagram B.V.	N/A
Unknown	Acupuncture in Persistent Atrial Fibrillation NCT02110537	Kyunghee University Medical Center	N/A
Completed	CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF) NCT01984346	AtriCure, Inc.	N/A
Terminated	Evaluation of the Phased Radio Frequency Ablation System NCT01693120	Medtronic Cardiac Ablation Solutions	N/A
Completed	SmartTouch Catheter for Left Anterior Line - SmarT Line Study NCT02217657	LMU Klinikum	N/A
Unknown	Left Atrial Appendage Electrical Isolation and Occlusion to Treat Persistent Atrial Fibrillation: A Safety and NCT02028130	Royal Brompton & Harefield NHS Foundation Trust	N/A
Completed	Therapeutic Outcomes Using Contact Force Handling During Atrial Fibrillation Ablation NCT01851525	Southlake Regional Health Centre	N/A
Completed	Evaluating the Efficacy and Feasibility of a Novel Wireless ECG Recording System in Monitoring Patients After NCT01912911	The Cleveland Clinic	—
Unknown	Endomyocardial Botulinum Toxin Injection in Patients With Persistent Atrial Fibrillation NCT02008448	Meshalkin Research Institute of Pathology of Circulation	Phase 2
Completed	Catheter Ablation of Drug-refractory Persistent Atrial Fibrillation With the HeartLight(TM) Laser Balloon in C NCT01863472	Boris Schmidt	N/A
Unknown	Pulmonary Vein Isolation Versus Botulinum Toxin Injection Plus Pulmonary Vein Isolation in Patients With Atria NCT02002923	Meshalkin Research Institute of Pathology of Circulation	Phase 2
Withdrawn	Comparison of Reverse Remodeling and PVI Versus CFAE and/or Linear Lesions and PVI for Persistent AF NCT01877473	Valley Health System	Phase 4
Unknown	Pulmonary Vein Antrum Isolation (PVAI) Plus Scar Homogenization and Non-PV Triggers Ensure Long-term Recurrenc NCT01672138	Texas Cardiac Arrhythmia Research Foundation	N/A
Unknown	Persistent Atrial Fibrillation Cryoballoon Ablation NCT02166723	Staten Island University Hospital	—
Terminated	Efficacy and Safety Study of the Estech COBRA® Surgical System to Treat Patients With a History of Irregular H NCT01683045	Endoscopic Technologies, Inc	N/A
Completed	ABLATE Post Approval Study - Synergy Ablation Lesions for Non-Paroxysmal Atrial Fibrillation NCT01694563	AtriCure, Inc.	N/A
Completed	A New Approach to Target the Substrates of Persistent Atrial Fibrillation: The Sequential Substrate Ablation A NCT02654353	Johannes Gutenberg University Mainz	Phase 4
Completed	Ranolazine in Atrial Fibrillation Following An ELectricaL CardiOversion NCT01534962	Menarini Group	Phase 2
Terminated	Ascending Dose Study of OPC-108459 Intravenous Infusions in Patients With Paroxysmal and Persistent Atrial Fib NCT01483183	Otsuka Pharmaceutical Development & Commercialization, Inc.	Phase 1
Unknown	Catheter Versus Thoracoscopic Surgical Ablation Strategy in Persistent Atrial Fibrillation NCT01385358	Royal Brompton & Harefield NHS Foundation Trust	N/A
Completed	Dual Epicardial Endocardial Persistent Atrial Fibrillation (AF) Study NCT01246466	AtriCure, Inc.	N/A
Completed	CatHeter Ablation of perSistEnd Atrial Fibrillation: Pulmonary Vein Isolation Versus Defragmentation. The CHAS NCT01580124	Universitätsklinikum Hamburg-Eppendorf	N/A
Completed	Effect of Empirical Left Atrial Appendage Isolation on Long-term Procedure Outcome in Patients With Persistent NCT01362738	Texas Cardiac Arrhythmia Research Foundation	Phase 3
Completed	Benefit of CFAE Ablation NCT01711047	Oxford University Hospitals NHS Trust	N/A
Unknown	Node and Atrial Fibrillation Ablation for Persistent Atrial Fibrillation NCT01057485	Eastbourne General Hospital	N/A
Withdrawn	Linear Ablation Versus Focal Ablation of Complex Fractionated Atrial Electrograms in Persistent Atrial Fibrill NCT01088126	Korea University Anam Hospital	N/A
Completed	Modified Ablation Guided by Ibutilide Use in Chronic Atrial Fibrillation NCT01014741	Vivek Reddy	N/A
Unknown	Irbesartan and Adhesion Molecules in AF NCT00613496	University of Magdeburg	Phase 4
Terminated	Clinical Value of Left Atrial Appendage Flow for Prediction of Successful Catheter Ablation for Persistent Atr NCT01144858	Clinique Pasteur	—
Completed	Atrial Fibrillation Management in Congestive Heart Failure With Ablation NCT00652522	Abbott Medical Devices	N/A
Completed	Ganglionated Plexi Ablation Combined With Pulmonary Vein Isolation NCT01703247	Meshalkin Research Institute of Pathology of Circulation	Phase 2
Completed	RAte Control Efficacy in Permanent Atrial Fibrillation NCT00392613	University Medical Center Groningen	N/A
Completed	Withdrawal Versus Continuation of Amiodarone in Successfully Treated Patients With Persistent Atrial Fibrillat NCT00845780	University Medical Center Groningen	Phase 4