| Recruiting | BoxX-NoAF Clinical Trial Post Operative Atrial Fibrillation, Atrial Fibrillation, Postoperative | N/A | 2025-10-24 |
| Recruiting | Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb Pain Amputation, Amputation of Lower Limb, Amputation of Upper Limb | — | 2025-04-01 |
| Active Not Recruiting | Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial Ischemic Stroke, Systemic Embolism | N/A | 2023-01-25 |
| Active Not Recruiting | HEAL-IST IDE Trial Inappropriate Sinus Tachycardia | N/A | 2022-05-31 |
| Completed | FREEZE-AFIB Post-Market Study Atrial Fibrillation, Atrial Flutter | — | 2022-04-29 |
| Active Not Recruiting | CONVERGE Post-Approval Study (PAS) Chronic Atrial Fibrillation | N/A | 2022-04-13 |
| Recruiting | Inappropriate Sinus Tachycardia Registry Inappropriate Sinus Tachycardia, Postural Tachycardia Syndrome | — | 2022-03-01 |
| Completed | VCLIP Post-Market Study, Long-term Follow-up on LAA Exclusion Using AtriClip Left Atrial Appendage Absent | N/A | 2022-01-27 |
| Withdrawn | CONVERGE CAP Study-For The Treatment Of Symptomatic Persistent or Long-standing Persistent AF Atrial Fibrillation | N/A | 2021-12-01 |
| Completed | aMAZE Trial Continued Access Protocol Atrial Fibrillation | N/A | 2020-03-09 |
| Active Not Recruiting | AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment Atrial Fibrillation (AF), Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation | N/A | 2019-01-30 |
| Recruiting | A Multicenter Patient Registry on Outcomes From Cryoanalgesia of the Intercostal Nerves Post Operative Pain | — | 2018-06-29 |
| Completed | The cryoICE™ CryoAnalgesia Study For Pain Management in Post thoRacic Procedures Via intercOSTal Cryoanalgesia Pain | N/A | 2016-06-13 |
| Completed | AtriClip® Left Atrial Appendage Exclusion Concomitant to Structural Heart Procedures (ATLAS) Post-Operative Atrial Fibrillation | Phase 4 | 2016-02-01 |
| Completed | Combined Endoscopic Epicardial and Percutaneous Endocardial Ablation Versus Repeated Catheter Ablation in Pers Atrial Fibrillation, Persistent and Longstanding Persistent Atrial Fibrillation | N/A | 2015-11-01 |
| Unknown | aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation Atrial Fibrillation | N/A | 2015-09-01 |
| Completed | Pivotal Study Of A Dual Epicardial & Endocardial Procedure (DEEP) Approach Atrial Fibrillation, Persistent or Longstanding Persistent Atrial Fibrillation | N/A | 2015-02-01 |
| Completed | Stroke Feasibility Study Atrial Fibrillation, AFib | Phase 1 / Phase 2 | 2014-01-01 |
| Completed | LARIAT RS: An Observational Study of the Performance and Safety of the LARIAT RS Atrial Appendage | N/A | 2014-01-01 |
| Completed | CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF) Persistent Atrial Fibrillation | N/A | 2013-12-01 |
| Recruiting | Tracking Results of Ablations to Combat AF Registry Generation 2 Atrial Fibrillation | — | 2013-02-01 |
| Completed | ABLATE Post Approval Study - Synergy Ablation Lesions for Non-Paroxysmal Atrial Fibrillation Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation | N/A | 2012-09-01 |
| Completed | Dual Epicardial Endocardial Persistent Atrial Fibrillation(AF) Study (Staged DEEP) Atrial Fibrillation | N/A | 2012-08-01 |
| Completed | Dual Epicardial Endocardial Persistent Atrial Fibrillation (AF) Study Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation | N/A | 2010-12-01 |
| Completed | Left Atrial Appendage Exclusion Study Atrial Appendage | N/A | 2009-12-01 |
| Completed | AtriCure Exclusion of the LAA in Patients Undergoing Concomitant Cardiac Surgery Left Atrial Appendage Exclusion | Phase 2 | 2008-09-01 |
| Completed | AtriCure Bipolar Radiofrequency Ablation of Permanent Atrial Fibrillation Atrial Fibrillation | Phase 3 | 2007-11-01 |
| Completed | Safety and Effectiveness of Left Atrial Appendage Occlusion Atrial Fibrillation | Phase 2 | 2007-09-01 |
| Unknown | Sole-Therapy Treatment of Atrial Fibrillation Atrial Fibrillation | Phase 2 | 2005-10-01 |
| Completed | Concomitant Treatment of Permanent Atrial Fibrillation Atrial Fibrillation | Phase 3 | 2005-01-01 |
| Withdrawn | AtriCure Bipolar Radiofrequency Ablation of Persistent Atrial Fibrillation Atrial Fibrillation | Phase 3 | — |
| Withdrawn | AtriCure Minimally Invasive Surgical Ablation for Atrial Fibrillation/RESTORE IIB Atrial Fibrillation | Phase 2 | — |