NCT02695277

Combined Endoscopic Epicardial and Percutaneous Endocardial Ablation Versus Repeated Catheter Ablation in Persistent and Longstanding Persistent Atrial Fibrillation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 146 (actual)
• Sponsor: AtriCure, Inc. · Industry
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This is a prospective, randomized (2:1) multicenter trial to investigate the optimal treatment of Persistent and Longstanding Persistent AF referred for Radiofrequency (RF) ablation.The study objective is to compare the efficacy and safety of two interventional approaches, in preventing the recurrence of AF in symptomatic, drug refractory patients with persistent or longstanding persistent atrial fibrillation.

Conditions

• Atrial Fibrillation
• Persistent and Longstanding Persistent Atrial Fibrillation

Interventions

Type	Name	Description
DEVICE	AtriCure Bipolar System
DEVICE	Standard Endocardial Ablation with Catheter
DEVICE	AtriClip® PRO LAA Exclusion System
DEVICE	Endocardial Ablation with Catheter
DEVICE	Repeated Endocardial ablation(s)

Timeline

• Start date: 2015-11-01
• Primary completion: 2022-11-01
• Completion: 2024-09-01
• First posted: 2016-03-01
• Last updated: 2024-10-15

Locations

12 sites across 5 countries: Czechia, Germany, Netherlands, Poland, United Kingdom