| Not Yet Recruiting | Inflammation in Clear Aligners With and Without Attachments NCT07506993 | University of Nebraska | — |
| Completed | Investigation of the Relationship Between Periodontitis and Alzheimer's Disease in Terms of Blood Parameters NCT07069244 | Uskudar University | — |
| Recruiting | Hyaluronic Acid and Octenidine Gel as an Adjunct to Non-surgical Periodontal Treatment NCT06522438 | Queen Mary University of London | N/A |
| Recruiting | PRF as Adjunct to Subgingival Instrumentation in Step 2 Periodontal Therapy NCT07013682 | University of Bern | N/A |
| Completed | Periodontal Pathogens and Atherom Plaque The Number of Mitochondrial DNA Copies NCT07165054 | Istanbul Saglik Bilimleri University | — |
| Active Not Recruiting | Hyaluronic Acid and Albumin-PRF in Non-Surgical Periodontal Therapy NCT07415148 | Inonu University | N/A |
| Recruiting | Hyaluronic Acid and Polynucleotides for Supra-bony Defects NCT06309719 | Queen Mary University of London | N/A |
| Completed | Analysis of the Impact of Contemporary Subgingival Debridement Techniques on Immunological Biomarkers in Gingi NCT07243145 | Selcen Ozcan Bulut | — |
| Unknown | Minimally Non Surgical Periodontal Therapy Compared to Traditional Approach NCT05060601 | Federico II University | N/A |
| Completed | The Effect of Non-surgical Periodontal Treatment on Dickkoff-1 and Secreted Frizzled Related Protein-5 Levels NCT06727929 | Cumhuriyet University | — |
| Enrolling By Invitation | Analysis of Early Healing of Sutures in Periodontal Surgery NCT06201377 | Ana María García de la Fuente | N/A |
| Unknown | Clinical Efficacy of Saffron Mouth Rinse in Periodontitis Patients With Renal Disease NCT06235021 | British University In Egypt | N/A |
| Completed | Thyme Honey Mouthwash in Management of Periodontitis in Renal Patients NCT06129097 | British University In Egypt | N/A |
| Completed | Electroacupuncture as an Adjunct to Non-Surgical Periodontal Therapy NCT06247007 | Didem OZKAL EMINOGLU | N/A |
| Enrolling By Invitation | Comparison of Gingival Flap Procedure Using Conventional Surgical Loupes vs. Videoscope for Visualization NCT05932017 | Texas A&M University | — |
| Recruiting | Characterization of JAK1 and JAK2 Activation in Gingival Tissues During Homeostasis and Periodontitis NCT07536204 | University of Chile | — |
| Completed | Diode Laser Photo Activation for Pocket Reduction Decontamination A Clinical Study NCT06404190 | Krishnadevaraya College of Dental Sciences & Hospital | Phase 1 |
| Unknown | NSPT On Vitronectin And Fetuin-A Levels In Patients With Periodontitis And Coronary Artery Disease NCT05663476 | Meenakshi Ammal Dental College and Hospital | N/A |
| Completed | The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups NCT06140394 | Faculty of Dental Medicine for Girls | N/A |
| Recruiting | The Role of Diet in Periodontal Inflammation: A Controlled Clinical Study NCT05864768 | G. d'Annunzio University | N/A |
| Unknown | Treatment of Advanced Periodontitis With a Chitosan Brush and a Chitosan Gel NCT05773911 | Caspar Wohlfahrt | N/A |
| Completed | Vitamin D Supplementation Prior to Non-surgical Periodontal Therapy NCT05398770 | University of Tromso | N/A |
| Completed | Therapeutic Application of Coconut Oil in Oral Health NCT06049589 | Fundacion Clinica Pardinas | N/A |
| Completed | Effects of Social Media on Oral Hygiene With Orthodontic Patients NCT06886984 | Karadeniz Technical University | N/A |
| Unknown | Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alteration NCT05439330 | University of Aarhus | N/A |
| Completed | GCF Annexin-A1, Carbonic Anhydrase-1, and Elongation Factor-1 Gamma Levels in Periodontitis NCT05680441 | Dokuz Eylul University | — |
| Completed | Analysis of the Factors Influencing the Occurrence of Peri-implant Inflammation in Patients With Oral Implant NCT06998160 | Hui Xie | N/A |
| Unknown | Effect of Adjunctive Use of Vitamin B3 and B9 on Myeloperoxidase Level in the GCF of Patients With Stage I and NCT05435378 | Cairo University | EARLY_Phase 1 |
| Completed | Impact of Daily Use of The Emanate Tray Adjunct to Full Mouth Debridement Compared to Full Mouth Debridement A NCT05282615 | Emanate Biomedical Inc. | N/A |
| Completed | Periodontal Parameters in Orthodontic Patients With Stainless Steel and Ceramic Brackets. NCT05144555 | University of Pavia | N/A |
| Completed | Indocyanine-green Mediated Photosensitizer VS Aloe Vera Gel: Adjunct Therapy to Scaling and Root Planing in Pa NCT04964167 | Riyadh Elm University | Phase 4 |
| Unknown | Impact of Non-surgical Periodontal Therapy on Oral and Gut Microbiome NCT04580355 | University of Campinas, Brazil | Phase 4 |
| Unknown | NSPT on Calprotectin and Periostin Levels NCT05618743 | Meenakshi Ammal Dental College and Hospital | N/A |
| Completed | Effect of Smartphone Application on Reducing Localized Inflammation in Periodontal Maintenance Patients NCT04546295 | University of Nebraska | N/A |
| Completed | The Periodontal Status and Failure Rates With Different Retainer Bonding Techniques Using One-step Adhesive NCT05458583 | Pamukkale University | N/A |
| Unknown | Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodonti NCT04606186 | University of Erlangen-Nürnberg | N/A |
| Completed | DNI Values After Periodontal Treatment NCT05666622 | Kahramanmaras Sutcu Imam University | N/A |
| Completed | Evaluation of Biomarkers Levels in Gingival Crevicular Fluid, Saliva and Serum for Different Periodontal Disea NCT05435131 | Akdeniz University | N/A |
| Unknown | Accuracy of Pulp Sensibility Test on Teeth With Deep Periodontal Pocket NCT04399135 | Qassim University | N/A |
| Unknown | Effect of Trait Anxiety in Women on Oral Health Status and Oral Health Care-Seeking Behavior NCT04274855 | Ain Shams University | — |
| Completed | Oral and Systemic aMMP-8 in Periodontal Disease NCT04268381 | Aydin Adnan Menderes University | — |
| Completed | Role of TLR2 and TLR4 in Stage 2 Periodontitis Patients NCT04201912 | Ajman University | N/A |
| Completed | Effect of Emdogain® on Soft Tissue Wound Healing NCT06179277 | Amir Azarpazhooh | N/A |
| Completed | GCF Galectin-3 and Interleukin-1beta Levels in Periodontitis. NCT05449093 | Aydin Adnan Menderes University | — |
| Completed | Genius Toothbrushes on Periodontal Status of Orthodontic Patients NCT04235010 | Pamukkale University | N/A |
| Completed | Topical Metronidazole vs Control in Reducing Periodontal Pockets in a Split Mouth Clinical Trial NCT06836401 | University of Salamanca | Phase 4 |
| Completed | Effects of Platelet Concentrates on Palatal Wound Healing NCT04097509 | Inonu University | N/A |
| Completed | Saliva Levels of S100A12, CRP, Fetuin-A in Periodontal Disease Patients NCT03345745 | Ordu University | — |
| Completed | Development of a New Toothpaste for the Removal of Dental Calculus. NCT04381403 | Faleh Tamimi | N/A |
| Completed | Low-level Laser Therapy as an Adjunct to Non-surgical Periodontal Treatment NCT05233501 | University of Beykent | N/A |
| Completed | Antimicrobial Photodynamic Therapy in Patients With Periodontal Disease and Type 2 Diabetes Mellitus NCT05816941 | University of Ljubljana | N/A |
| Completed | Laser Biostimulation in Periodontal Treatment NCT04253613 | Ondokuz Mayıs University | — |