NCT03345745

Saliva Levels of S100A12, CRP, Fetuin-A in Periodontal Disease Patients

The Short-Term Effects of Non-Surgical Periodontal Therapy on The Saliva Levels of S100A12, High-Sensitivity C-Reactive Protein and Fetuin-A in Patients With Gingivitis and Chronic Periodontitis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 54 (actual)
• Sponsor: Ordu University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

Hs-CRP, Fetuin-A and S100A12 are acute phase proteins associated with many systemic diseases and conditions. The aim of this study was to determine the clinical parameters and salivary Hs-CRP, Fetuin-A and S100A12 levels before and after non-surgical periodontal treatments in the patients with periodontal diseases. A total of 54 subjects were divided in to three groups; periodontally healthy (n: 18), gingivitis (n: 18), chronic periodontitis (n: 18). Clinical periodontal parameters, salivary Hs-CRP, Fetuin-A and S100A12 levels and salivary flow rates were evaluated at baseline and a month after the treatments. Salivary Hs-CRP, Fetuin-A and S100A12 levels were assayed by ELISA.

Conditions

• Periodontal Inflammation

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	salivary samples	Salivary Hs-CRP, Fetuin-A and S100A12 levels and salivary flow rates were evaluated at baseline and a month after the treatments

Timeline

• Start date: 2017-02-01
• Primary completion: 2017-06-01
• Completion: 2017-09-01
• First posted: 2017-11-17
• Last updated: 2017-11-17

Locations

1 site across 1 country: Turkey (Türkiye)