Trials / Completed
CompletedNCT04268381
Oral and Systemic aMMP-8 in Periodontal Disease
Local And Systemic Levels of aMMP-8 in Gingivitis and Stage 3 Periodontitis
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 83 (actual)
- Sponsor
- Aydin Adnan Menderes University · Academic / Other
- Sex
- All
- Age
- 25 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
Periodontal disease is an inflammatory process that can result in tooth loss and also is considered a modifying factor for systemic health. Matrix metalloproteinase (MMP)-8 is the major collagenase of periodontal tissue breakdown. The aim of the present study is to analyze active (aMMP-8) levels in gingival crevicular fluid (GCF), saliva and serum in the context of new criteria of gingivitis and stage 3 grade C periodontitis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Biochemical analysis | aMMP-8 is measured by immunofluorometric assay (IFMA). |
Timeline
- Start date
- 2020-01-20
- Primary completion
- 2020-03-20
- Completion
- 2020-03-20
- First posted
- 2020-02-13
- Last updated
- 2020-07-14
Locations
1 site across 1 country: Turkey (Türkiye)
Source: ClinicalTrials.gov record NCT04268381. Inclusion in this directory is not an endorsement.