NCT06836401

Topical Metronidazole vs Control in Reducing Periodontal Pockets in a Split Mouth Clinical Trial

Effect of Topical Metronidazole in Reducing Periodontal Probing Depth: A Split Mouth Clinical Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University of Salamanca · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The effect of both the mechanical treatment and the topical metronidazol in reduccing the inflammation and depth of the periodontal pockets were assessed on the first bicuspids.

Conditions

• Periodontal Disease
• Periodontal Inflammation

Interventions

Type	Name	Description
PROCEDURE	Root scaling	Scaling and root planing is a deep cleaning below the gumline used to remove plaque and tartar that cover the root in the periodontal pockets. This intervention is carried out in both control and experimental sites
DRUG	Topical Gel	A gel (experimental: metronidazole VS control: carbopol) is introduced in the recently cleaned periodontal pocket. The allocation of either experimental or control gel was distributed randomly, being masked both the patient and the clinician.

Timeline

• Start date: 2018-10-10
• Primary completion: 2022-10-10
• Completion: 2022-11-10
• First posted: 2025-02-20
• Last updated: 2025-07-24

Locations

1 site across 1 country: Spain