| Not Yet Recruiting | Vaginal Vault Native Tissue Suspension NCT07517965 | Assiut University | N/A |
| Recruiting | Centered Surgery - Preoperative Counseling and Patient Satisfaction NCT07471464 | The Cleveland Clinic | — |
| Recruiting | SORE Study: Sitz Baths After Urogynecologic Reconstruction NCT07215780 | Yale University | N/A |
| Recruiting | Pelvic Floor Muscle Training During Pregnancy NCT07104292 | University of Southern Denmark | N/A |
| Enrolling By Invitation | Enabling Self-Care for Pessary Users in Rural Setting NCT07084818 | Dartmouth-Hitchcock Medical Center | N/A |
| Recruiting | The AccelERate Trial NCT07218016 | NICHD Pelvic Floor Disorders Network | N/A |
| Not Yet Recruiting | Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy NCT07175805 | Hartford HealthCare | — |
| Recruiting | Effects of Pelvic Floor Muscle Training With & Without Hypopressive Exercises NCT07440875 | Riphah International University | N/A |
| Recruiting | Sequence of Midurethral Sling Placement During Robotic Sacrocolpopexy NCT07008898 | University of Alabama at Birmingham | N/A |
| Recruiting | VNOTES Approach in Mesh Free Sacrocolpopexy: A Functional and Anatomic Evaluation NCT07114029 | Gaziosmanpasa Research and Education Hospital | N/A |
| Recruiting | Comparison of V-NOTES and Laparoscopic Mesh-Free Sacrocolpopexy Techniques NCT07082023 | Havva Betül Bacak | N/A |
| Completed | Comparison of Mesh-Based and Mesh-Free Laparoscopic Pectopexy in Uterus-Preserving Surgery for Apical Prolapse NCT07080957 | Havva Betül Bacak | N/A |
| Not Yet Recruiting | Perioperative Follow-up Protocols for Pelvic Organ Prolapse Surgery NCT06631508 | Saglik Bilimleri Universitesi | N/A |
| Completed | Postoperative Pain Management Following Robotic Assisted Sacrocolpopexy NCT06309693 | University of Alabama at Birmingham | N/A |
| Enrolling By Invitation | i-Stitch for Bilateral Sacrospinous Ligament Fixation (SSLF) NCT06805006 | A.M.I. Agency for Medical Innovations GmbH | — |
| Recruiting | POMEGRANATE Trial: Comparing Reia Pessary Versus Standard of Care Pessary for Pelvic Organ Prolapse Treatment NCT06634459 | Medstar Health Research Institute | N/A |
| Not Yet Recruiting | Fat Injection for Rectocele Treatment: A Novel Approach NCT06604702 | Cairo University | N/A |
| Not Yet Recruiting | Vaginal Prolapse Pessary Material Trial PVC vs Silicon NCT06641804 | Princess Margaret Hospital, Hong Kong | N/A |
| Completed | Comprehensive Nursing Care Protocol for Women With Pelvic Organ Prolapse and Urinary Incontinence: A Global Pe NCT06639217 | Delta University for Science and Technology | N/A |
| Recruiting | Physical Therapy Intervention for Pelvic Organ Prolapses NCT06532292 | National Taiwan University Hospital | N/A |
| Recruiting | Comparison of Postoperative Outcomes of Laparoscopic Lateral Suspension and V-NOTES Lateral Suspension With th NCT06802497 | Gaziosmanpasa Research and Education Hospital | — |
| Withdrawn | Tranexamic Acid in Vaginal Reconstructive Surgery NCT06419075 | The University of Texas Medical Branch, Galveston | Phase 4 |
| Not Yet Recruiting | Safety and Efficacy of Different Procedures of Colpocleisis: a Randomized Controlled Trial NCT06482697 | Lan Zhu | N/A |
| Not Yet Recruiting | The Impact of Long-term Pessary Use on Pelvic Organ Prolapse oìduring Covid-19 Pandemic in Patients Attending NCT06234449 | IRCCS San Raffaele | — |
| Not Yet Recruiting | A Randomized Controlled Trial of Modified Ischial Spinous Fascia Fixation and Sacrospinous Ligament Fixation i NCT06418451 | Lan Zhu | N/A |
| Not Yet Recruiting | Comparison of Learning Curves for Two Different Techniques in Vaginal Hysterectomy NCT06220253 | IRCCS San Raffaele | N/A |
| Not Yet Recruiting | Patient Education in the Clinical Management of Pessary NCT06432218 | Peking Union Medical College Hospital | N/A |
| Not Yet Recruiting | A Randomized Controlled Trail of Uterosacral Ligament Suspension in the Treatment of Pelvic Organ Prolapse NCT06418438 | Lan Zhu | N/A |
| Recruiting | Pelvic Floor Rehabilitation of Female Pelvic Floor Dysfunction NCT06461234 | Mingfu Wu | — |
| Terminated | Prospective Randomized Controlled Trial of Obstructed Defecation Surgery NCT05747027 | Endeavor Health | N/A |
| Recruiting | Pectopexy for Apical Prolapse Management NCT06369857 | Assiut University | N/A |
| Recruiting | The Influence of Using Vascularized Vaginal Flap on the Efficacy of Mesh-augmented Sacrospinous Hysteropexy NCT06494982 | Saint Petersburg State University, Russia | N/A |
| Unknown | Intelligent Diagnosis and Treatment System for Pelvic Floor Dysfunction in Elderly Women NCT06372340 | Beijing Hospital | N/A |
| Completed | Evaluation of Anatomical Results and Sexual Functions After Unilateral and Bilateral Laparoscopic Suture Sacro NCT06341088 | Ataturk University | N/A |
| Active Not Recruiting | Effect of Local Estriol Treatment Before Vaginal Repair Surgery NCT06391372 | Hatice Tukenmez Kurnaz | Phase 3 |
| Completed | Impact of Defecation Posture on Ease of Bowel Movements in Patients With a Rectocele NCT06252714 | TriHealth Inc. | N/A |
| Completed | Attitude and Success Rate of Women With Pelvic Organ Prolapse on Self-management of Vaginal Pessary NCT06246721 | Chinese University of Hong Kong | N/A |
| Completed | Association With Low Compliance Bladder in Women With LUTS NCT06210477 | National Taiwan University Hospital | — |
| Active Not Recruiting | Biological Mesh Versus Synthetic Mesh in Interdisciplinary RRP With SCP NCT06245577 | Evangelisches Klinikum Köln Weyertal gGmbH | N/A |
| Active Not Recruiting | Vaginal Orthosis Use After Vaginal Reconstructive Surgery NCT05812859 | University of Alabama at Birmingham | N/A |
| Completed | Gamma-irradiated Amniotic Membrane Graft in Posterior Colporrhaphy NCT06117670 | Ain Shams Maternity Hospital | Phase 3 |
| Completed | Evaluation of the Results of Laparoscopic Sacrohysteropexy and Sacrocolpopexy Surgeries Performed Without Mesh NCT06176521 | Gaziosmanpasa Research and Education Hospital | N/A |
| Recruiting | Multicenter Ventral Mesh Rectopexy Registry Collaborative NCT05918367 | University Hospital, Antwerp | — |
| Not Yet Recruiting | Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery NCT06050161 | Kern Medical Center | N/A |
| Completed | A New POP (Pelvic Organ Prolapse) Scoring System: Validity and Reliability NCT06520722 | Cairo University | — |
| Completed | Intraperitoneal Bupivacaine for Pelvic Organ Prolapse NCT06120530 | Indiana University | Phase 4 |
| Completed | Retroperitoneal Tunneling Versus Dissection Technique During Sacrocolpopexy NCT05969067 | The University of Texas Medical Branch, Galveston | N/A |
| Completed | Comparison of Vaginal Axis on MRI in Alternative Apical Prolapse Surgeries to Sacrocolpopexy NCT06072456 | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | N/A |
| Unknown | Urinary Catheter Self-Discontinuation After Urogynecology Surgery NCT05860634 | University of Texas at Austin | N/A |
| Active Not Recruiting | Platelet Rich Plasma as an Adjunct Therapy at the Time of Transvaginal Native Tissue Prolapse Surgery NCT05731284 | University of Alabama at Birmingham | N/A |
| Recruiting | Long-term Success Rate of Transvaginal Mesh for the Treatment of Pelvic Organ Prolapse: The Extended RCT Study NCT05938881 | Peking Union Medical College Hospital | — |
| Recruiting | Pessary Experience Study NCT06021769 | University of Virginia | — |
| Unknown | PDS Versus Prolene as Suture Material for Vaginal Sacrospinous Hysteropexy NCT05964881 | Medical University of Vienna | N/A |
| Unknown | Laparoscopic Sacropexy and Vaginal Natural Orifice Transluminal Endoscopic Surgery Shull Suspension Comparison NCT05856201 | Azienda Ospedaliero, Universitaria Pisana | N/A |
| Active Not Recruiting | Superiority of Perineoplasty as Concomitant Surgical Procedure During Pelvic Organ Prolapse Repair NCT05713422 | Marjolein Spiering | — |
| Recruiting | The Intermediate and Long-term Follow up of Home Based Pelvic Muscle Training NCT05778552 | Taipei Veterans General Hospital, Taiwan | — |
| Unknown | Self-management Pessary Project NCT05885711 | Zuyderland Medisch Centrum | — |
| Completed | Absorbable Suture vs Permanent Suture in Sacrospinous Ligament Suspension NCT05688059 | Atlantic Health System | N/A |
| Unknown | Vaginal Axis on Magnetic Resonance Imaging After Laparoscopic Pectopexy Surgery: a Controlled Study NCT05876975 | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | N/A |
| Unknown | Comparison of Sacrospinous Ligament Fixation and Uterosacral Ligament Suspension for Apical Prolapse Surgery: NCT05668130 | B.P. Koirala Institute of Health Sciences | N/A |
| Completed | Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery NCT05658887 | Joseph Kowalski | Phase 4 |
| Unknown | Kegal Exercises With and Without Postural Correction on Postpartum Pelvic Organ Prolapse in Primiparous Women NCT05851729 | Riphah International University | N/A |
| Withdrawn | VESPER: Pelvic Organ Prolapse Study NCT03995797 | Hampshire Hospitals NHS Foundation Trust | N/A |
| Terminated | Vaginal Estradiol Use in Pessary Care NCT05458375 | University of South Florida | EARLY_Phase 1 |
| Recruiting | Long-term Evaluation of the Efficacy and Safety of Splentis for the Treatment of Primary Apical Pelvic Organ P NCT05042453 | Promedon | — |
| Active Not Recruiting | Clinical Investigation of the da Vinci Surgical System NCT05682742 | Intuitive Surgical | N/A |
| Recruiting | Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS NCT05602246 | Charles University, Czech Republic | N/A |
| Completed | Comparison of Suturing Technique Types on Pubocervical Fascia at Colpographhy Anterior for Cystocele Repair NCT05444023 | Kanuni Sultan Suleyman Training and Research Hospital | N/A |
| Completed | Comparison of Post-operative Symptoms After Two Surgeries for Patients With Pelvic Organ Prolapse NCT05697796 | Peking University People's Hospital | — |
| Completed | Measuring Abdominal Wall Compliance During Gynecologic Laparoscopic Surgery NCT05012956 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | EVeRLAST 2-Year Follow-Up NCT05542836 | Duke University | — |
| Active Not Recruiting | The Influence of Simultaneous Posterior Colporrhaphy and Perineoplasty on the Efficiency and Safety of Mesh-au NCT05422209 | Saint Petersburg State University, Russia | N/A |
| Unknown | Comparison of Vaginal and Laparoscopic Apical Fixation Techniques for Pelvic Organ Prolapse Treatment NCT05420831 | Saint Petersburg State University, Russia | N/A |
| Completed | Lidocaine for Pessary Check Pain Reduction NCT05493735 | University of South Florida | Phase 3 |
| Completed | Pelvic Floor Muscle Training With and Without Hypopressive Exercises in Postmenopausal Females. NCT05719584 | Riphah International University | N/A |
| Enrolling By Invitation | Digital Care Programs for Female Pelvic Health NCT05513417 | Sword Health, SA | — |
| Recruiting | Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth NCT05530681 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Vaginal Adventitia Reserved and Anatomical Implant Technique of Transvaginal Mesh Procedure for Pelvic Organ P NCT05707533 | West China Hospital | — |
| Recruiting | Efficacy/Safety of Urogynecology Synthetic Mesh Surgery NCT05682989 | Mackay Medical College | — |
| Completed | The Impact of a Redesigned Handout for Robotic Sacrocolpopexy on Patient Preoperative Preparedness and Satisfa NCT06934304 | University of Texas Southwestern Medical Center | N/A |
| Recruiting | Transvaginal Sacrospinous Hysteropexy Versus Laparoscopic Uterine Lateral Suspension NCT05586984 | National Cheng-Kung University Hospital | — |
| Completed | Pectopexy Surgery Without Mesh NCT05715489 | Gaziosmanpasa Research and Education Hospital | N/A |
| Recruiting | ASIA-Mesh: a Pilot Study for Diagnostics and Treatment on ASIA Syndrome Caused by Polypropylene Mesh Implantat NCT06363903 | Maxima Medical Center | — |
| Unknown | Laparoscopic Hysterectomy With Vaginal Vault Suspension to the Uterosacral Ligaments for Stage II-III Pelvic O NCT03553511 | Università degli Studi dell'Insubria | N/A |
| Recruiting | Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry NCT04829175 | Ethicon, Inc. | — |
| Active Not Recruiting | Post-market Clinical Follow-up of the SRS Implant NCT05170074 | pfm medical gmbh | — |
| Completed | Postoperative Return to Sexual Activity NCT05342090 | University of Calgary | N/A |
| Completed | Continence After Vaginal Prolapse Surgery NCT05312047 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Completed | Health Care Seeking Behavior and Knowledge Assessment of Hungarian Women About Pelvic Floor Disorders NCT05567900 | University of Pecs | — |
| Completed | Comparing Postoperative Pain After Vessel Sealing Device Versus Conventional Suturing Methods for Vaginal Hyst NCT05192954 | Marlana McDowell | N/A |
| Completed | Comparison of Laparoscopic Pectopexy and Laparoscopic Lateral Suspension Techniques in Uterine-preserving Apic NCT05143658 | Kanuni Sultan Suleyman Training and Research Hospital | N/A |
| Recruiting | GYNEMESH PS Mesh Post Marketing Clinical Follow-Up Study NCT04829058 | Ethicon, Inc. | — |
| Completed | Feasibility Study of the Reia Vaginal Pessary NCT04508335 | Reia, LLC | N/A |
| Unknown | Axis(TM) Solvent-dehydrate Dermal Allograft in the Treatment of Pelvic Organ Prolapse. NCT06263985 | Michigan Institution of Women's Health PC | Phase 4 |
| Terminated | Pelvic Floor Disorders Among Sexual Minoritized Women NCT05072158 | University of New Mexico | — |
| Active Not Recruiting | Pelvic Organs Prolapse Treatment Using Neodymium Laser NCT05000957 | MeLSyTech, Ltd | N/A |
| Completed | Vaginal Transluminal Endoscopic Sacrocolpopexy NCT06004089 | Dr. Lutfi Kirdar Kartal Training and Research Hospital | N/A |
| Unknown | the Anatomical Reduction and Functional Recovery Effects of Two Transvaginal Apical Slings on Pelvic Organ Pro NCT05189665 | Peking University People's Hospital | N/A |
| Unknown | BOTOX® at the Time of Prolapse Surgery for OAB NCT04807920 | Walter Reed National Military Medical Center | Phase 4 |
| Completed | The Effectiveness of an Online Exercise Program on Well-being of Postpartum Women NCT06268782 | University of Turku | N/A |
| Completed | Materna Prep Study Phase II NCT06126328 | Materna Medical | Phase 2 |
| Completed | Evaluation of the Results of Lateral Suspension Surgeries Performed With the V-NOTES (Vaginal-Natural Orifice NCT05066737 | Gaziosmanpasa Research and Education Hospital | N/A |
| Unknown | Flat Polypropylene Mesh in the Treatment of Uterine and Recurrent or Advanced Pelvic Organ Prolapse NCT06225375 | Michigan Institution of Women's Health PC | Phase 1 / Phase 2 |
| Completed | Patient Educational Video for Pelvic Organ Prolapse NCT04996563 | Ohio State University | N/A |
| Completed | Race, Ethnicity, Socioeconomic Status and Prolapse-rElated Decisional ConflicT NCT04977141 | Women and Infants Hospital of Rhode Island | — |
| Unknown | Continuous Stitches Versus Simple Interrupted Stitches for Anterior Colporrhaphy NCT05449054 | Medical University of Vienna | N/A |
| Not Yet Recruiting | Sacrocolpopexy Versus Sacro-spinous Fixation for Prolapse Treatment NCT04878146 | Centre Hospitalier Universitaire Vaudois | N/A |
| Completed | Urinary Retention After Removing Urinary Catheter at 24 Hour Versus 48 Hour in Patients With Vaginal Surgery NCT04954443 | Department of Medical Services Ministry of Public Health of Thailand | N/A |
| Completed | Same Day Discharge Following Pelvic Reconstructive Surgery NCT04804826 | TriHealth Inc. | — |
| Unknown | Questionnaire of Lower Urinary Tract Symptoms Among Women Before and After Surgical Correction of Uterine Prol NCT06260436 | Assiut University | — |
| Completed | Caregiver Support and Post-operative Convalescence NCT04897061 | Icahn School of Medicine at Mount Sinai | — |
| Completed | Pelvic Floor Disorder Assessment of Knowledge and Symptoms: an Educational Model in Spanish-Speaking Women NCT04829721 | Johns Hopkins University | N/A |
| Unknown | Radiofrequency and Pelvic Organ Prolapse NCT04855071 | Fundació d'investigació Sanitària de les Illes Balears | N/A |
| Completed | Improving Female Sexual Wellness NCT04824820 | Cedars-Sinai Medical Center | N/A |
| Unknown | Pain After Insufflation for Robotic Sacrocolpopexy (PAIRS) Trial NCT04858438 | Henry Ford Health System | N/A |
| Unknown | Preoperative Analgesia by Infiltration of the Pudendal Nerve Prior to Sacrospinous Ligament Suspension NCT04733560 | Fraser Health | N/A |
| Active Not Recruiting | Prospective Long-term Evaluation of the Efficacy and Safety of Calistar S for Transvaginal Pelvic Organ Prolap NCT03821142 | Promedon | N/A |
| Completed | Electrical Stimulation in Women With Pelvic Organ Prolapse NCT04733885 | KTO Karatay University | N/A |
| Unknown | Combination of Laparoskopic Uterosacral Ligament and Round Ligament Plication, A Meshless Method in the Surgic NCT04894032 | Zeynep Kamil Maternity and Pediatric Research and Training Hospital | — |
| Unknown | Pelvic Ultrasound Pessary Study: Changes in Pelvic Anatomy After Placing a Pessary NCT04915664 | Universiteit Antwerpen | — |
| Withdrawn | Sprix for Postoperative Pain Control Following Gynecologic Surgery NCT04444830 | University of Louisville | Phase 4 |
| Completed | Early Feasibility Study of the Reia Vaginal Pessary NCT04275089 | Reia, LLC | N/A |
| Completed | Alfacalcidol Supplementation on Levator Ani Muscle Strength of Menopausal Pelvic Organ Prolapse Patients NCT05505253 | Universitas Padjadjaran | Phase 3 |
| Unknown | Effect of Electroacupuncture on Symptoms of Female Pelvic Organ Prolapse(Level II - III) NCT04589715 | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | N/A |
| Completed | Transobturator Lateral Suspension in Anterior Colporrhaphy NCT07144397 | University Medical Centre Maribor | N/A |
| Active Not Recruiting | To Explore the Surgical Outcomes and Safety of an Innovative Laparoscopic Uterine Pectopexy Technique Using In NCT07411898 | Chung Shan Medical University | — |
| Completed | Impact of Level III Support Procedure on Enlarged Genital Hiatus After Minimally Invasive Sacrocolpopexy NCT04480671 | University of Pittsburgh | N/A |
| Completed | Post-operative Cognitive Function Following Pelvic Floor Surgery NCT04554550 | University of Pennsylvania | — |
| Completed | Effects of the Addition of Uterosacral Ligament Plication to Pectopexy Operation on Anatomical and Subjective NCT04508062 | Ataturk University | N/A |
| Completed | Educating Women About Pelvic Floor Disorders During Pregnancy NCT05440539 | The Methodist Hospital Research Institute | N/A |
| Completed | Evolution of Symptoms After Anterior Sacrospinofixation by Autologous Tissues NCT04270188 | Hospices Civils de Lyon | — |
| Unknown | Comparison of Posterior and Anterior Approach to Sacrospinous Ligament Apical Fixation - Randomized Controlled NCT04306250 | HaEmek Medical Center, Israel | N/A |
| Completed | Expedited Versus Restrictive: Limitations on Activity Following Surgical Treatment of Prolapse NCT04329715 | Duke University | N/A |
| Unknown | Hysterectomy Versus Uterine Preservation for Pelvic Organ Prolapse Surgery NCT04890951 | University of Calgary | — |
| Unknown | A Feasibility Study on the Value of Pelvic Floor Training After Pelvic Organ Prolapse Surgery NCT04539782 | Landspitali University Hospital | N/A |
| Unknown | What is the Effect of Prolapse Surgery on Voiding? NCT04429360 | Universiteit Antwerpen | — |
| Unknown | The Effect of the Mode of Delivery to the Pelvic Floor Function NCT04474275 | Giresun University | — |
| Unknown | Impact of Female Pelvic Reconstruction Surgery on Lower Urinary Tract Symptoms, Psychosomatic Distress and Sex NCT04416152 | Far Eastern Memorial Hospital | — |
| Unknown | A Novel Approach to Posterior Mesh Fixation in Laparoscopic Sacral Colpopexy NCT04358978 | Catholic University of the Sacred Heart | N/A |
| Completed | Modified Purandare's Cervicopexy Versus Abdominal Sacral Hysteropexy NCT04852991 | Ain Shams Maternity Hospital | N/A |
| Unknown | Surgical Intervention With DermaPure vs Native Tissue in Pelvic Organ Prolapse NCT03939715 | Colorado Pelvic Floor Consultants | Phase 4 |
| Completed | Predictors of Recovery Expectancy NCT04274491 | Indiana University | — |
| Completed | Early Safety of Resection Recopy and Sacrocolpopexy NCT05910021 | Evangelisches Klinikum Köln Weyertal gGmbH | — |
| Completed | Gentamicin Intravesical Efficacy for Infection of Urinary Tract NCT04246996 | Kaiser Permanente | Phase 2 |
| Unknown | Abdominal Sacral Hysteropexy Versus Vaginal Sacrospinous Hysteropexy NCT04850365 | Ain Shams University | N/A |
| Completed | Comparison of Laparoscopic Sacrohysteropexy, Modified Laparoscopic Lateral Suspension and Laparoscopic Pectope NCT04178083 | Diyarbakir Women's and Children's Diseases Hospital | — |
| Completed | LOOP VS DOUBLE SUTURE TECHNIQUES IN SACROSPINOUS FIXATION: A TWO-YEAR STUDY NCT07106866 | Zeynep Kamil Maternity and Pediatric Research and Training Hospital | — |
| Terminated | 3D Translabial Ultrasound for Pessary Size Estimation NCT03955744 | Western University, Canada | N/A |
| Recruiting | AMBULAPSE STUDY Feasibility Study on Laparoscopic Double-mesh Sacrocolpopexy With or Without Robotic Assistanc NCT03764852 | Centre Hospitalier Universitaire de Nice | N/A |
| Active Not Recruiting | EASE: The Materna Prep Pivotal Study NCT03973281 | Materna Medical | N/A |
| Active Not Recruiting | Intraoperative Costs and Patient Perceptions in Sacrocolpopexy for Prolapse NCT04179955 | Mayo Clinic | — |
| Completed | Evaluation of Neuromuscular Morphometry of the Vaginal Wall NCT06363838 | Gaziosmanpasa Research and Education Hospital | — |
| Completed | Laparoscopic Fascial Duplication Plus Sacral Colpopexy in Posterior Vaginal Prolapse NCT05252637 | Azienda Ospedaliera Cardinale G. Panico | N/A |
| Completed | Vaginal Probiotics and Pessaries and Their Impact on the Vaginal Microenvironment NCT04118049 | Hartford Hospital | N/A |
| Completed | Evaluation of Safety and Efficacy of the Apyx™ Device for the Repair of Pelvic Organ Prolapse (POP) NCT03991455 | Escala Medical LTD | N/A |
| Completed | Safety and Efficacy of Non-ablative Er:YAG Laser Therapy for the Treatment of Pelvic Organ Prolapse and Coexis NCT04417413 | Aleksandra Novakov Mikic | — |
| Unknown | The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures NCT04172272 | General Hospital Pula | N/A |
| Recruiting | Quality of Life After Conservative and Surgical Treatment of Pelvic Organ Prolapse NCT04110821 | University Hospital, Basel, Switzerland | — |
| Unknown | CREDE Study: Intraoperative Crede Manoeuver Compared to Preoperative Prolapse Reduction Stress Test to Predict NCT04087642 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Completed | Voiding Assessment Based on Minimum Spontaneous Void of 150 mL Compared to Retrograde Fill Method After Female NCT03539107 | Yale University | N/A |
| Completed | Lessons on Urethral Lidocaine in Urodynamics NCT04038099 | University of Texas Southwestern Medical Center | Phase 4 |
| Completed | Pudendal Nerve Block in Vaginal Surgery NCT04198714 | MetroHealth Medical Center | N/A |
| Completed | Pelvic Floor Muscles and Success in the Surgical Treatment of Stress Urinary Incontinence and Pelvic Organ Pro NCT04029168 | Żelazna Medical Centre, LLC | — |
| Completed | Enhanced Recovery Protocol in Urogynecologic Surgery NCT04175782 | Kanuni Sultan Suleyman Training and Research Hospital | N/A |
| Completed | Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures NCT04048356 | University of New Mexico | Phase 3 |
| Completed | Evaluation of the Benefits of Enhanced Recovery After Surgery (ERAS) Protocol in Pelvic Prolapse NCT04008654 | Kanuni Sultan Suleyman Training and Research Hospital | N/A |
| Unknown | Three-dimensional Ultrasound Assessment in Cases of Prolapse Surgeries NCT03857724 | Assiut University | N/A |
| Completed | Enhanced Consent and Preparedness for Surgery Trial NCT03988569 | Loyola University | N/A |
| Completed | Urinary Track Infection Prevention After Urogynecological Surgery NCT03818321 | TriHealth Inc. | Phase 2 |
| Recruiting | A Multi-center Registry Study: The Follow-up the Complications for Trans-vaginal Mesh Surgery NCT04025047 | Peking Union Medical College Hospital | — |
| Completed | Patient Preparedness for Pelvic Organ Prolapse Surgery NCT03836365 | University of Pittsburgh | N/A |
| Unknown | Mesh Debate Awareness Among Non-urogynecologists. A Practical Survey Study. NCT04010162 | Uludag University | — |
| Completed | Pelvic Floor and Sexual Dysfunction in Women With Sjogren's Syndrome NCT04415710 | Akdeniz University | — |
| Withdrawn | The Effect of Local Analgesia on Postoperative Gluteal Pain in Patients Undergoing Sacrospinous Ligament Fixat NCT03995641 | Kettering Health Network | Phase 4 |
| Completed | Impact of Decision Aids in Urogynecology NCT04369404 | Massachusetts General Hospital | N/A |
| Completed | Minimally Invasive Burch Colposuspension to Reduce Occult Stress Incontinence NCT03841513 | Northwestern University | N/A |
| Completed | Total Laparoscopic Hysterectomy With Sacrocolpopexy Versus Total Laparoscopic Hysterectomy With Lateral Suspen NCT03722563 | Antalya Training and Research Hospital | N/A |
| Unknown | Apical Pelvic Support in Infertility Patients NCT04039009 | Uludag University | — |
| Completed | Lateral Suspension and Sacropexy for Pelvic Organ Prolapse NCT03772691 | Assiut University | N/A |
| Unknown | Evaluation of Functional Outcomes After Laparoscopic Promontofixation (PFL). NCT03919123 | University Hospital, Caen | — |
| Unknown | The Efficacy of Transcutaneous Electrical Nerve Stimulation on LUTS: One Prospective Study. NCT03634722 | Peking University People's Hospital | N/A |
| Unknown | Lateral Suspension Versus Sacral Colpopexy POP NCT03644628 | Medical University of Vienna | N/A |
| Unknown | Inflammation and Cellular Immunity in Vaginal Tissue in Patients With Pelvic Organ Prolapse NCT03748693 | Hillel Yaffe Medical Center | — |
| Unknown | Sacrospinous Ligament Fixation With Conventional Surgical Instruments in Chinese Apical Prolapse Female Patien NCT03782285 | Peking Union Medical College Hospital | — |
| Unknown | Nonabsorbable Versus Absorbable Sutures for Anterior Colporrhaphy NCT03736811 | Seoul National University Hospital | N/A |
| Completed | Clinical Outcomes of Transvaginal Mesh Procedures for Cystocele Repair: Comparisons of Uphold and Perigee Syst NCT03764891 | Far Eastern Memorial Hospital | — |
| Completed | Calistar A vs. Calistar S - Comparative Cohort Retrospective Analysis of Single Incision POP Systems NCT03715803 | Agustin Sampietro | — |
| Completed | Same Day Discharge After Minimally-invasive Sacrocolpopexy NCT03730103 | The Cleveland Clinic | N/A |
| Unknown | Does a High BMI Affect Supervised Pelvic Floor Muscle Training for Improving Symptoms in Women With Various St NCT04009694 | University of Salford | N/A |
| Active Not Recruiting | Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologi NCT03522961 | Brigham and Women's Hospital | N/A |
| Completed | Vaginal Tactile Imaging for the Assessment of Pelvic Organ Prolapse Repair Efficiency NCT03311685 | Rambam Health Care Campus | N/A |
| Completed | Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery NCT03524339 | University Hospitals Cleveland Medical Center | Phase 2 / Phase 3 |
| Completed | Study of Outpatient Management for Promontofixation by Laparoscopy NCT03573752 | University Hospital, Strasbourg, France | N/A |
| Completed | Pelvic Floor Dysfunction and Its Influence on Body Image and Sexual Function NCT03591393 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Different Types of Suture for Sacral Colpopexy NCT03582410 | Catholic University of the Sacred Heart | N/A |
| Completed | Advanced Biomarker Assessment in Pelvic Organ Prolapse NCT03642054 | Mayo Clinic | — |
| Completed | Testing a Decision Aid for Women With Urogenital Prolapse NCT03706716 | University of Southern Denmark | N/A |
| Unknown | The Follow-up of Mesh/Native Tissue Complications Study(Part II) NCT03617211 | Peking Union Medical College Hospital | — |
| Completed | Laparoscopic Sacrocolpexy Versus Lateral Suspension NCT03582852 | Assistance Publique Hopitaux De Marseille | N/A |
| Completed | Dynamic Magnetic Resonance Imaging Before and After Vaginal Prolapse Repair NCT03315715 | TriHealth Inc. | — |
| Completed | Apical Support During Hysterectomy for Pelvic Organ Prolapse-NSQIP Analysis. NCT03421067 | TriHealth Inc. | — |
| Completed | Vaginally Assisted Laparoscopic Hysteropexy Versus Vaginal Hysterectomy NCT03436147 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | — |
| Completed | Laparoscopic Lateral Suspension With Mesh & Sacrocervicopexy for the Treatment of Uterine Prolapse NCT03421457 | Fatih Sultan Mehmet Training and Research Hospital | N/A |
| Unknown | Comparing Transvaginal Self-tailored Titanium-coated Polypropylene Mesh Procedure With Mesh-kit Procedure. NCT03283124 | Peking Union Medical College Hospital | N/A |
| Unknown | RCT for Transvaginal Self-cut Mesh vs Mesh-kit for Severe POP NCT03849157 | Peking Union Medical College Hospital | N/A |
| Unknown | Does Intravenous Tranexamic Acid Reduce Blood Loss During Vaginectomy? NCT03216083 | Mount Sinai Hospital, Canada | Phase 3 |
| Completed | Postoperative Opioid Consumption After Urogyneocologic Surgery NCT03586219 | University of California, Irvine | N/A |
| Completed | Apical Support During Hysterectomy for Pelvic Organ Prolapse NCT03379246 | TriHealth Inc. | — |
| Unknown | Anchor for Robotic Sacrocolpopexy NCT03378622 | Kaiser Permanente | Phase 3 |
| Completed | SMAD2, SMAD3 AND TGF-β GENE EXPRESSION IN URGE URINARY INCONTINENCE NCT04525105 | Muğla Sıtkı Koçman University | — |
| Terminated | The Effect of Abdominal Binder Use on Postoperative Pain and Mobility in Patients Undergoing Pelvic Surgery NCT03684304 | University Hospitals Cleveland Medical Center | N/A |
| Completed | Physical Therapy on Pelvic Organ Prolapse NCT03244397 | University of Alcala | N/A |
| Completed | Postoperative Virtual Clinical Encounters NCT04138810 | University of Pennsylvania | N/A |
| Terminated | Pelvic Floor Support After Laparoscopic Hysterectomy for Benign Conditions: A Randomized Controlled Trial Comp NCT03753516 | Walter Reed National Military Medical Center | N/A |
| Completed | Pelvic Floor Muscle Training Programme in Pregnant Nepalese Women- a Feasibility Study NCT03349736 | Kathmandu University School of Medical Sciences | N/A |
| Unknown | POPQ Versus Simulated Apical Support as a Guideline for Anterior or Posterior Repair During Vaginal Reconstruc NCT03187054 | Seoul National University Hospital | N/A |
| Completed | Gabapentin for Postop Pain After SSLF NCT03123861 | University of North Carolina, Chapel Hill | Phase 4 |
| Completed | Preoperative Levator Ani Muscle Injection and Pudendal Nerve Block for Pain Control After Vaginal Reconstructi NCT03040011 | Lauren Giugale, MD | Phase 1 / Phase 2 |
| Completed | Smartmesh Technology in Pelvic Floor Repair Procedures NCT03098641 | Groupe Hospitalier de la Rochelle Ré Aunis | — |
| Completed | Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery NCT03052816 | University Hospitals Cleveland Medical Center | Phase 4 |
| Completed | Single Versus Multi-port Robotic Assisted Sacrocolpopexy for Repair of Vaginal Apex Prolapse NCT03034499 | Rambam Health Care Campus | N/A |
| Completed | Reducing Postoperative Catheterization NCT03009968 | University of North Carolina, Chapel Hill | N/A |
| Completed | Catheter Management After Pelvic Reconstructive Surgery NCT03071211 | Hartford Hospital | N/A |
| Completed | Identifying Stress Urinary Incontinence in Women With Pelvic Organ Prolapse NCT03005977 | The Cleveland Clinic | N/A |
| Active Not Recruiting | Materiovigilance After Urinary Incontinence or Prolapse Surgery NCT03052985 | Poitiers University Hospital | — |
| Completed | Preoperative Oestrogen in Postmenopausal Women With Pelvic Organ Prolapse NCT03779633 | Medical University of Vienna | Phase 4 |
| Completed | The Development of De-novo Stress Urinary Incontinence After Stage II-III Pelvic Organ Prolapse Surgery NCT03221725 | Kanuni Sultan Suleyman Training and Research Hospital | N/A |
| Completed | Does the Use of Bupivacaine Soaked Vaginal Packing Following Vaginal Surgery Decrease Postoperative Pain? NCT03266926 | Sunnybrook Health Sciences Centre | — |
| Completed | Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery NCT03048682 | The Cleveland Clinic | N/A |
| Unknown | Gabapentin Reduces Opioid Use Postoperatively ("GROUP Study") NCT02999724 | Mount Sinai Hospital, Canada | Phase 3 |
| Completed | Pelvic Floor Exercise Before Surgery in Women With Pelvic Organ Prolapse NCT03064750 | St. Olavs Hospital | N/A |
| Withdrawn | Does Dexamethasone Administration Improve Recovery In Patients Undergoing Minimally Invasive Sacrocolpopexy? NCT03094442 | The Cleveland Clinic | N/A |
| Completed | Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen NCT02431897 | University of Texas Southwestern Medical Center | Phase 4 |
| Active Not Recruiting | SCP vs HUSLS for Pelvic Organ Prolapse Repair NCT02800512 | Loma Linda University | N/A |
| Completed | Vaginal Packing After Laparoscopic Sacrocolpopexy NCT02943525 | Charles University, Czech Republic | N/A |
| Completed | Laparoscopic Lateral Mesh Suspension for Pelvic Organ Prolapse NCT03387202 | Fatih Sultan Mehmet Training and Research Hospital | — |
| Unknown | Extended Pessary Interval for Care (EPIC Study) NCT01644214 | Unity Health Toronto | N/A |
| Active Not Recruiting | Composite Outcomes of Mesh vs Suture Techniques for Prolapse Repair: A Randomized Controlled Multicentre Trial NCT02965313 | University of British Columbia | N/A |
| Completed | A Randomized Controlled Trial of Permanent vs Absorbable Suture for Uterosacral Ligament Suspension NCT02888093 | Joseph Kowalski | N/A |
| Completed | Laparoscopic Sacrocolpopexy Versus POPS in the Management of Pelvic Prolapse NCT02911584 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Unknown | Effect of Local Anesthesia on Postoperative Pain Following Sacrospinous Ligament Fixation NCT02890199 | Hartford Hospital | N/A |
| Completed | Vaginal Tactile Imaging for Pelvic Floor Prolapse NCT02925585 | Artann Laboratories | — |
| Unknown | Laparoscopic Retrovesical Colpopectinopexia NCT02919852 | Orel Regional Hospital, Russia | N/A |
| Active Not Recruiting | Comparison of the Efficacy of Sacrocolpopexy, the Amreich-Richter Procedure and Transvaginal Mesh NCT03053479 | Charles University, Czech Republic | N/A |
| Unknown | The 3D Reconstruction Research of Pelvic Organ Prolapse Disease NCT03146195 | Nanfang Hospital, Southern Medical University | — |
| Completed | Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery NCT02727322 | Halina M Zyczynski, MD | Phase 4 |
| Completed | Video Decision Aid in Latina Women With Pelvic Organ Prolapse NCT02850835 | Texas Tech University Health Sciences Center, El Paso | N/A |
| Unknown | Native Tissue Repair With Surgical Pelvic Organ Pessary - an RCT NCT02808377 | Cambridge University Hospitals NHS Foundation Trust | N/A |
| Completed | VITOM Study: A Randomized, Controlled Trial. NCT03120689 | University of Louisville | N/A |
| Unknown | Pelvic Floor Symptoms After Bilateral Sacrospinous Fixation NCT02998216 | University Hospital Tuebingen | — |
| Unknown | Comparison of Two Apical Repair Methods in Women Undergoing Repairs for Prolapse NCT03113513 | Medical University of Graz | N/A |
| Completed | Uterosacral Ligament Suspension vs Robotic Sacrocolpopexy NCT02741830 | TriHealth Inc. | — |
| Completed | Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use NCT02680145 | Mayo Clinic | N/A |
| Unknown | Trial Comparing Laparoscopic Vs Robotic-assisted Colposacropexy for Pelvic Organ Prolapse Repair NCT02852512 | University Of Perugia | N/A |
| Completed | Uterosacral Ligament Suspension Clip NCT02700997 | TriHealth Inc. | N/A |
| Completed | Evaluation of the Relationship Between Vaginal and Lower Urinary Tract Microbiomes and Infection After Hystere NCT02751073 | Mayo Clinic | — |
| Terminated | Early Versus Late Voiding Trials After Prolapse Repair NCT02739256 | University of Pittsburgh | N/A |
| Completed | Day Case Laparoscopic Sacrocolpopexy, a New Management NCT03607344 | Centre Hospitalier Universitaire de Nice | — |
| Unknown | Continuous Locked Non-barbed Suture for Mesh Fixation During Laparoscopic Sacral Colpopexy for Severe Pelvic O NCT03427606 | Azienda Ospedaliera Cardinale G. Panico | N/A |
| Completed | Comparison of Anatomic Results Between Bilateral and Conventional Abdominal Sacral Hysteropexy NCT02667002 | Zeynep Kamil Maternity and Pediatric Research and Training Hospital | N/A |
| Withdrawn | Use of Pre-Emptive Pudendal Nerve Block for Pelvic Reconstructive Surgery NCT02409498 | Icahn School of Medicine at Mount Sinai | N/A |
| Completed | An Intervention to Improve Prolapse Using Femmeze® (v1) NCT02280382 | Royal Cornwall Hospitals Trust | N/A |
| Unknown | Prospective Randomized Study to Compare Results of Pelvic Organ Prolapse Repair With One Versus Two Vaginal Me NCT02536001 | Ziv Hospital | N/A |
| Unknown | the Indications and Clinical Efficacy of Pelvic Organ Prolapse Surgery NCT02599311 | Peking University People's Hospital | Phase 3 |
| Completed | A Long Term Follow up of Anterior Meshes for Recurrent Prolapse NCT02642835 | Medway NHS Foundation Trust | — |
| Completed | Pudendal Nerve Block for Postoperative Posterior Repair Pain Relief NCT02502591 | Royal Devon and Exeter NHS Foundation Trust | Phase 2 |
| Completed | Perineorrhaphy Outcomes Related to Body Imagery NCT02548858 | University of New Mexico | N/A |
| Completed | Healing Statements and Their Effect on Post Operative Pain NCT02502357 | Medstar Health Research Institute | N/A |
| Completed | Vaginally Assisted Laparoscopic Sacropolpopexy NCT04332315 | Bezmialem Vakif University | N/A |
| Completed | The Effect of an Additional Stress Incontinence Procedure on Overactive Bladder During Pelvic Organ Prolapse R NCT02502838 | Icahn School of Medicine at Mount Sinai | — |
| Completed | Native Tissue Repair in Pelvic Organ Prolapse -Long-term Results and Risk of Re-operation NCT06744972 | Turku University Hospital | — |
| Unknown | The Pelvic Floor Function and Sexual Life of the Women After Different Type of Hysterectomy NCT02841059 | Buddhist Tzu Chi General Hospital | — |
| Completed | Permanent Versus Absorbable Colpopexy Trial NCT02277925 | University of North Carolina, Chapel Hill | N/A |
| Unknown | Comparisons of Clinical Outcomes Between Novel Tailored Transvaginal Mesh Surgery and Vaginal Native Tissue Re NCT02465710 | National Taiwan University Hospital | — |
| Unknown | Risk Factors for Co-existence of Cervical Elongation in Uterine Prolapse NCT02465658 | National Taiwan University Hospital | — |
| Completed | Improvement of Pain Following Robotic Sacrocolpopexy and Rectocele Repair for Pelvic Organ Prolapse NCT02449915 | TriHealth Inc. | Phase 4 |
| Completed | Safety and Performance of the EndoFast Reliant SCP in Vaginal Wall Reinforcement NCT03516136 | Allium, Ltd. | — |
| Completed | Analysis of Procedural Times Using Colpassist for Robotic-Assisted Sacrocolpopexy; a Randomized Controlled Tri NCT02367235 | University of North Carolina, Chapel Hill | N/A |
| Completed | Risk Factors for Recurrence After Pelvic Reconstruction NCT03457883 | Nanjing Medical University | N/A |
| Completed | Timing of Pessary Care NCT02371083 | Hartford Hospital | N/A |
| Unknown | FINPOP 2015: Incidence, Methods, Complications and Quality of Life of Pelvic Organ Prolapse Operations in Finl NCT02716506 | Society for Gynecological Surgery in Finland | — |
| Completed | Effect of Standardized Consent for Urogynecological Procedures on Patient Satisfaction NCT02313701 | Beth Israel Deaconess Medical Center | N/A |
| Completed | A Pilot Study to Investigate the Efficacy of Partially Absorbable Mesh in Patients With Pelvic Organ Prolapsed NCT02320643 | Samyang Biopharmaceuticals Corporation | N/A |
| Completed | Clinical and Urodynamic Evaluation of Surgical Repair of Pelvic Organ Prolapse Associated With Lower Urinary T NCT04793126 | Ain Shams University | Phase 2 |
| Completed | Laparoscopic Three-dimensional Versus Two-dimensional Sacral Colpopexy and Paravaginal Repair NCT02258230 | Olympus Corporation of the Americas | N/A |
| Completed | Population-based Estimates of Medical Comorbidities in Women With Lower Urinary Tract Symptoms or Pelvic Organ NCT01590576 | Far Eastern Memorial Hospital | — |
| Completed | Safety and Efficacy Study of the NeuGuide Device NCT02190825 | Pop Medical Solutions | N/A |
| Completed | Follow-up Study After Manchester Operation for Pelvic Organ Prolapse NCT02246387 | Oslo University Hospital | — |
| Completed | L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract to Prevent Postoperative Urinary Tract Infection. NCT02216253 | IRCCS San Raffaele | N/A |
| Completed | Vaginal Tactile Imaging in Assessment of Pelvic Floor Conditions NCT02294383 | Artann Laboratories | — |
| Terminated | Exair® Versus Native Tissue Repair for Prolapse NCT02162628 | Coloplast A/S | — |
| Unknown | R&D Supporting Pilot Study for the Assessment of the Safety and Effectiveness of the ProVATE (ProTIPI) Vaginal NCT02239133 | ConTIPI Medical | N/A |
| Completed | Restorelle® Mesh Versus Native Tissue Repair for Prolapse NCT02162615 | Coloplast A/S | — |
| Completed | Restricted Convalescence: Outcomes Following Urogynecologic Procedures NCT02138487 | Northwestern University | N/A |
| Completed | Comparison of 2 Lightweight Y-meshes After Laparoscopic Sacrocolpopexy NCT02248935 | Atlantic Health System | — |
| Completed | Study to Assess Duration of Indwelling Catheter After Sacrocolpopexy NCT02189291 | Oregon Health and Science University | N/A |
| Completed | IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair NCT02155738 | Halina M Zyczynski, MD | Phase 4 |
| Completed | ACell MatriStem Pelvic Floor Matrix Versus Native Tissue Repair, Comparative Study NCT02021279 | Integra LifeSciences Corporation | N/A |
| Completed | Guided IMagery and Patient Satisfaction (GIMPS) Following Urogynecological Surgery NCT02165280 | Loyola University | N/A |
| Completed | Effect of a Risk Calculator on Patient Satisfaction With the Decision for Midurethral Sling During Prolapse Su NCT02111642 | Medstar Health Research Institute | N/A |