NCT06604702

Fat Injection for Rectocele Treatment: A Novel Approach

Fat Injection for Treatment of Rectocele a Novel Technique for Treatment of Tectocele

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: Female
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This clinical trial aims to evaluate the effectiveness of autologous fat grafting as a novel treatment for rectocele, a condition characterized by the herniation of rectal tissue into the posterior vaginal wall. Women aged 18 to 60 years with mild to moderate rectocele, presenting with symptoms such as obstructive defecation or vaginal bulge, will undergo submucosal fat injections. The study will assess the procedure\'s ability to alleviate symptoms and reduce prolapse recurrence. This prospective, single-arm trial will be conducted at Cairo University Hospitals.

Conditions

• Rectocele
• Pelvic Organ Prolapse
• Obstructive Defecation Syndrome

Interventions

Type	Name	Description
PROCEDURE	Autologous Fat Injection for Rectocele	In this procedure, autologous fat is harvested from the patient\'s lower abdomen using a multiport cannula. The fat is then processed via centrifugation to separate the viable fat cells, which are emulsified into nanofat. This nanofat is injected into the submucosal layer of the rectocele through the posterior vaginal wall, using an anoscope for guidance. The procedure is intended to reinforce the rectovaginal fascia, alleviate rectocele symptoms such as obstructive defecation and vaginal bulge, and reduce prolapse recurrence.

Timeline

• Start date: 2024-10-20
• Primary completion: 2025-10-20
• Completion: 2025-10-20
• First posted: 2024-09-19
• Last updated: 2024-09-19