| Recruiting | AERA Pediatrics Registry Dysfunction of Eustachian Tube | — | 2025-06-17 |
| Withdrawn | Tissue Quality of Integra vs. BTM Treated Burns Burn Injury, Burn Scar, Burn Wounds - Partial Thickness (2nd Degree) | — | 2025-03-01 |
| Completed | MicroMatrix® Flex in Tunneling Wounds Pressure Injury, Venous Ulcer, Necrotizing Soft Tissue Infection | N/A | 2024-12-12 |
| Enrolling By Invitation | A Modified Platform Trial of Multiple CAMPs for the Management of Diabetic Foot Ulcers and Venous Leg Ulcers Diabetic Foot Ulcer, Venous Leg Ulcer | N/A | 2024-11-18 |
| Recruiting | Bactiseal Catheter Safety Registry Study Hydrocephalus | — | 2024-09-29 |
| Completed | Cavitronic Ultrasonic Surgical Aspiration (CUSA) Women's Health Study Vulvar Intraepithelial Neoplasia, Condylomata Acuminata | — | 2024-02-23 |
| Completed | T-GENVIH-003 LTFU (Long Term Follow Up) Study Hernia, Hernia, Ventral, Pathological Conditions, Anatomical | — | 2023-09-12 |
| Withdrawn | The CUSA Clarity Bone Tip Study Cranial Skull Base Bone Removal | — | 2023-06-01 |
| Completed | External Ventricular Drainage Post-Market Clinical Follow-up Registry Cerebrospinal; Disorder | — | 2023-03-03 |
| Active Not Recruiting | Post Market Clinical Follow-up of CODMAN CERTAS Programmable Valve Hydrocephalus, Hydrocephalus in Children, NPH (Normal Pressure Hydrocephalus) | — | 2023-01-24 |
| Completed | Gentrix® Surgical Matrix for Soft Tissue Reinforcement in Ventral Hernia Repair Ventral Hernia | — | 2022-11-22 |
| Terminated | REINVENT Registry (Registry of the Nerve Gap Repair From Integra) Peripheral Nerve Injuries | — | 2022-05-30 |
| Terminated | NeuraGen 3D Pilot Study Digital Nerve Injury | N/A | 2022-05-15 |
| Completed | The SurgiMend PRS Retrospective Study Reconstructive Surgical Procedures | — | 2022-01-31 |
| Completed | The Purpose of This Study is to Determine Whether CerebroFlo™ EVD Catheter is Effective During the Treatment o Intraventricular Hemorrhage, Subarachnoid Hemorrhage | N/A | 2021-09-15 |
| Withdrawn | AmnioExcel® Plus vs SOC in the Management of Diabetic Foot Ulcers Diabetic Foot Ulcer | N/A | 2021-09-01 |
| Completed | Suturable DuraGen™ PMCF Study Cerebrospinal Fluid Leak | — | 2021-04-28 |
| Recruiting | The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation Supratentorial Hemorrhage | — | 2020-10-23 |
| Completed | Bactiseal Catheter Safety Registry in China Hydrocephalus | — | 2020-09-01 |
| Completed | A Study on the Safety of Hakim Programmable Shunt System Hydrocephalus | — | 2020-05-02 |
| Completed | The CUSA Clarity Soft Tissue Removal Study Benign, Malignant Tumors or Other Soft Tissue Removal, Nephrectomy or Partial Nephrectomy With Parenchyma Removal | — | 2020-03-30 |
| Completed | CERTAS Programmable Valve Registry Hydrocephalus, NPH (Normal Pressure Hydrocephalus), IIH - Idiopathic Intracranial Hypertension | — | 2019-11-21 |
| Terminated | Diabetic Foot Ulcer Study Comparing Cytal Wound Matrix 1-Layer to Standard of Care Diabetes, Diabetic Foot, Diabetes Mellitus, Type 2 | N/A | 2019-05-21 |
| Completed | Sundt™ Carotid Shunt Retrospective Post Market Clinical Follow-up Study (PMCF) Carotid Artery Stenosis | — | 2019-04-25 |
| Terminated | The Management of Pilonidal Wounds With ACell MicroMatrix® and Cytal® Wound Matrix: A Case Series Pilonidal Disease | — | 2019-03-26 |
| Terminated | Cytal® Wound Matrix and MicroMatrix® Wound Study Wounds | — | 2018-12-11 |
| Withdrawn | A Study to Evaluate the Efficacy of Cytal® Burn Matrix in the Management of Partial-Thickness Burns to the Han Partial Thickness Burn of Hand | N/A | 2018-08-01 |
| Completed | AMNIOEXCEL® Plus vs A Marketed Comparator vs SOC in the Management of Diabetic Foot Ulcers Diabetic Foot Ulcer | N/A | 2018-05-03 |
| Completed | Comparing Concomitant Use of ACell MicroMatrix® and ACell Cytal™ to Standard of Care in Stage 3 or 4 Pressure Pressure Ulcers Stage III, Pressure Ulcer, Stage IV, Pressure Ulcer | N/A | 2017-04-01 |
| Withdrawn | SurgiMend in Two-stage Implant-based Breast Reconstruction in Patients With Pre-Mastectomy Radiotherapy Breast Cancer | N/A | 2017-01-01 |
| Completed | PriMatrix for the Management of Diabetic Foot Ulcers Diabetic Foot Ulcer | N/A | 2017-01-01 |
| Terminated | Open-Label Study in Diabetic Foot Ulcers (DFU), to Evaluate Safety of 0.03% DSC127 Topical Gel in Chronic Use Diabetic Foot Ulcer | Phase 3 | 2015-12-01 |
| Terminated | MEDIHONEY® Gel Versus Collagenase for Wound Debridement Ulcer, Wounds | N/A | 2015-06-01 |
| Terminated | Global Sinus Surgery Registry Chronic Rhinosinusitis, Recurrent Acute Rhinosinusitis | — | 2015-01-01 |
| Completed | Duragen® Secure Post Marketing Clinical Follow-up (PMCF) Dura Mater Nick Cut or Tear, Surgery | — | 2014-10-01 |
| Completed | Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers Diabetic Foot Ulcers | N/A | 2014-07-01 |
| Completed | ACell MatriStem Pelvic Floor Matrix Versus Native Tissue Repair, Comparative Study Pelvic Organ Prolapse | N/A | 2014-06-11 |
| Completed | Study of Safety and Efficacy for the Eustachian Tube Balloon Catheter Eustachian Tube Dysfunction | N/A | 2014-02-01 |
| Completed | Retrospective Study Evaluating Outcomes for Integra® Skin Sheet Products in Lower Extremity Complex Wounds Complex Lower Extremity Soft Tissue Reconstruction | — | 2013-08-01 |
| Terminated | A Comparative Efficacy Study: Treatment for Non-healing Diabetic Foot Ulcers Foot Ulcer, Diabetic | N/A | 2013-05-01 |
| Terminated | Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diab Diabetic Foot Ulcers | Phase 3 | 2013-04-01 |
| Terminated | Phase III Study to Evaluate Efficacy and Safety of DSC127 in Diabetic Foot Ulcers Diabetic Foot Ulcers | Phase 3 | 2013-02-01 |
| Completed | Prospective, Multicenter Observational Study Evaluating the Long Term Safety of the Custombone Implant Surgery | — | 2012-12-01 |
| Completed | Comparison of Balloon Sinuplasty In-Office Versus Medical Management for Recurrent Acute Sinusitis Patients (C Recurrent Acute Rhinosinusitis | N/A | 2012-10-01 |
| Terminated | Health Economic Assessment of Lower Extremity Diabetic (HEALED) Ulcers With PriMatrix Foot Ulcer, Diabetic | N/A | 2012-09-01 |
| Completed | Medical Therapy Versus Balloon Sinus Dilation for Patients With Chronic Rhinosinusitis Sinusitis | — | 2012-09-01 |
| Completed | Earset Healthy Volunteer Study Otitis Media | — | 2012-05-01 |
| Terminated | Canadian Health Economics, Outcome, and Effectiveness Comparison of Treatment in Patients With Chronic Rhinosi Chronic Rhinosinusitis | N/A | 2012-02-01 |
| Completed | Tympanostomy Tube Placement in Children in the Office (Inova Study) Otitis Media | N/A | 2011-12-01 |
| Completed | inVENT-visIOn Study Otitis Media | N/A | 2011-10-01 |
| Completed | DuraSeal Exact Spine Sealant System Post-Approval Study Dural Sealing | — | 2011-08-01 |
| Terminated | A Multi-center, Prospective, Randomized Study With PriMatrix and PriMatrix Ag for the Treatment of Venous Leg Venous Stasis Ulcer | N/A | 2011-06-01 |
| Completed | Healthy Volunteer Study Anesthesia of Tympanic Membrane | — | 2011-04-01 |
| Completed | inVENT-In-Office Study Otitis Media | N/A | 2011-01-01 |
| Terminated | A Study With Primatrix Dermal Repair Scaffold For The Treatment Of Diabetic Foot Ulcers Foot Ulcer, Diabetic | N/A | 2010-12-01 |
| Completed | Evaluation of the Tympanostomy Tube Delivery System Otitis Media With Effusion, Acute Otitis Media | Phase 2 / Phase 3 | 2010-09-01 |
| Completed | A Multicenter, Prospective, Observational Study With PriMatrix for the Treatment of Neuropathic Diabetic Foot Foot Ulcers, Diabetic | — | 2010-08-01 |
| Completed | A Safety and Efficacy Study of INTEGRA® Dermal Regeneration Template for the Treatment of Diabetic Foot Ulcers Neuropathic Diabetic Ulcer - Foot | N/A | 2010-04-01 |
| Completed | Optimization and Refinement of Technique in In-Office Sinus Dilation 2 Sinusitis | — | 2010-04-01 |
| Completed | Acclarent Tympanostomy Tube Delivery System for the Treatment of Patients Requiring Tympanostomy Tube Insertio Otitis Media | N/A | 2010-02-01 |
| Terminated | An Evaluation of SprayShield in Reducing Post-Operative Adhesion Formation Following Major Open Abdominal Surg Ulcerative Colitis, Familial Polyposis | N/A | 2009-10-01 |
| Completed | Anesthetizing the Tympanic Membrane in Healthy Volunteers Evaluate Performance and Reliability of Iontophoresis System | N/A | 2009-08-01 |
| Completed | Large Abdominal Hernia Repair With SurgiMend 3.0 Hernia | — | 2009-04-01 |
| Completed | Clinical Study of the Tympanostomy Tube Delivery System Otitis Media With Effusion | N/A | 2009-03-01 |
| Completed | Singapore Tympanostomy Tube Delivery System Study Otitis Media | N/A | 2008-12-01 |
| Completed | Post Market Study for an Adhesion Barrier Following Laparoscopic Myomectomy Fibroid, Myoma, Leiomyoma | N/A | 2008-11-01 |
| Terminated | PleuraSeal Pivotal Study (US) Open Thoracotomy | Phase 3 | 2008-08-01 |
| Completed | Clinical Study of Safety and Efficacy for the Relieva Stratus With Elution of Triamcinolone Acetonide Sinusitis | N/A | 2008-08-01 |
| Completed | Anesthetic Effect of Lidocaine/Epinephrine Solution Delivered Via Iontophoresis to External Auditory Apparatus Acute Otitis Media, Chronic Otitis Media, Recurrent Acute Otitis Media | N/A | 2008-04-01 |
| Completed | Balloon Sinus Dilation In Office or OR Chronic Sinusitis | N/A | 2008-04-01 |
| Completed | PleuraSeal Post Market Study (Europe) Lung Disease, Pulmonary Lobectomy | Phase 4 | 2008-01-01 |
| Withdrawn | The Use of Bioscaffolds in Conjunction With Negative Pressure Therapy: A Prospective Randomized Double-Blinded Foot Ulcer, Diabetic | N/A | 2008-01-01 |
| Terminated | Ascension® Humeral Resurfacing Arthroplasty (HRA) Follow-Up Study Arthritis | — | 2007-12-01 |
| Completed | Study to Evaluate Safety & Effectiveness of Spinal Sealant Cerebrospinal Fluid Leakage, Subdural | N/A | 2007-05-01 |
| Terminated | Clinical Evaluation of the Ethmoid Sinus Spacer Sinusitis, Chronic Rhinosinusitis | N/A | 2007-04-01 |
| Terminated | Study to Evaluate Safety & Effectiveness of Vascular Sealant System Peripheral Vascular Disease | N/A | 2007-04-01 |
| Completed | Safety and Efficacy of Balloon Sinuplasty in Pediatric Sinusitis Chronic Sinusitis | N/A | 2007-04-01 |
| Terminated | DuraGen Plus® Adhesion Barrier for Use in Spinal Surgery Spinal Injuries, Adhesions | N/A | 2006-10-01 |
| Completed | Study to Evaluate Safety and Effectiveness of Spinal Sealant Spinal Procedure Requiring Dura Incision | N/A | 2005-09-01 |
| Completed | DuraSeal Sealant Post Market Study Elective Cranial Procedures With Dural Incision | N/A | 2005-09-01 |
| Completed | Clinical Evaluation to Confirm Safety and Efficacy of Sinuplasty in the Paranasal Sinuses (CLEAR) Chronic Sinusitis | Phase 3 | 2005-04-01 |