Trials / Conditions / Osteo Arthritis Knee

Osteo Arthritis Knee

228 registered clinical trials studyying Osteo Arthritis Knee — 38 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Measurement of Osteoarthritic Patient Pain Through Electrodermal Activity Signals NCT06701461	Dartmouth-Hitchcock Medical Center	N/A
Recruiting	Arthrosemid vs. Steroid for the Management Knee Osteoarthritis NCT07489521	Cappagh National Orthopaedic Hospital	Phase 4
Active Not Recruiting	Multimodal Treatment of Knee Osteoarthritis: Therapeutic Exercise and Noninvasive Neuromodulation (NESA) Versu NCT07258693	University of Jaén	N/A
Recruiting	Combined Use of PRP and Hyaluronic Acid for Infiltrative Treatment of Patients With Knee Osteoarthritis NCT06685120	Istituto Ortopedico Rizzoli	N/A
Not Yet Recruiting	Safety and Tolerability of StroMel™ in Subjects with Moderate to Severe Osteoarthritis of the Knee Joint NCT04750252	Akan Biosciences, LLC	Phase 1 / Phase 2
Enrolling By Invitation	Osteoarthritis Care Tools for Primary Care Providers NCT06988163	University of North Carolina, Chapel Hill	N/A
Active Not Recruiting	Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty NCT07141316	University of Pavia	N/A
Recruiting	The Role of Vitamin K on Knee Osteoarthritis Outcomes NCT06385275	Boston University	Phase 1 / Phase 2
Not Yet Recruiting	Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia NCT06264362	Drexel University	N/A
Recruiting	An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects With Moderate to Severe Osteoarthritis of t NCT06485843	Ageless Biotech, Inc.	Phase 2
Recruiting	Intermittent Hypoxia-Hyperoxia Combined With Physical Therapy for Knee Osteoarthritis NCT06965946	Khyber Medical University Peshawar	N/A
Recruiting	Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2) NCT06058169	Augusta University	N/A
Completed	Impact of Breathing and Yoga Poses on Kinesiophobia in Knee Osteoarthritis Patients NCT07325032	Saveetha University	N/A
Active Not Recruiting	SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization NCT06550024	CrannMed	N/A
Recruiting	The Effect of a 2-week Preoperative Vegan Diet Versus Omnivorous Diet on the Protein Turnover in the Osteoarth NCT06130956	Wageningen University	N/A
Active Not Recruiting	Radiographic Migration Analysis of the ATTUNE Cementless CR Fixed-Bearing Total Knee Replacement NCT06189872	Canadian Radiostereometric Analysis Network	N/A
Recruiting	Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis NCT06257537	ZetrOZ, Inc.	Phase 2
Enrolling By Invitation	Extended Oral Tranexamic Acid After Total Knee Arthroplasty NCT06618820	Campbell Clinic	Phase 3
Recruiting	Total Versus Robotic Assisted Unicompartmental Knee Replacement NCT05290818	NHS Lothian	N/A
Suspended	Low Frequency Ultrasound for Osteoarthritis Healing and Rehabilitation NCT06562374	The University of Texas Medical Branch, Galveston	N/A
Completed	Investigation of the Effect of Movement Mobilization Concept on Sensory, Pain, Muscle Activation in Patients W NCT06527313	Istinye University	N/A
Recruiting	The Effect of Body Mass Index on Short-term Results of HTO NCT06590818	Egymedicalpedia	N/A
Completed	OrthoCor Advanced Trial for Knee Osteoarthritis NCT06475677	Caerus Corporation	N/A
Recruiting	Intra-articular Injection of UC-MSC Exosome in Knee Osteoarthritis NCT06431152	Universidad de los Andes, Chile	EARLY_Phase 1
Enrolling By Invitation	EXPAREL IPSA Block in Knee Arthroplasty NCT06619340	Campbell Clinic	Phase 4
Not Yet Recruiting	In Vivo Kinematics for Subjects Having a MicroPort Medial Pivot or DePuy Attune PCR TKA NCT04103502	The University of Tennessee, Knoxville	—
Completed	Effects of Exercise Versus Topical Agents on Knee Osteoarthritis NCT05827003	Istanbul University - Cerrahpasa	N/A
Active Not Recruiting	Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis NCT06121882	Lipogems International spa	Phase 3
Enrolling By Invitation	Persona IQ Cohort Study NCT06089291	Zimmer Biomet	—
Recruiting	Efficacy of Bioceramic Materials for Bone Defects Repair NCT06249906	Nanjing First Hospital, Nanjing Medical University	N/A
Recruiting	The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After T NCT05487053	Negovsky Reanimatology Research Institute	N/A
Not Yet Recruiting	Comparison Between Intra-articular Infiltrations of PRP, MFAT, and PRP-MFAT in the Treatment of Symptomatic Kn NCT06084637	Assistance Publique Hopitaux De Marseille	Phase 3
Recruiting	Metformin Safety and Efficacy in Osteoarthritis. NCT06231758	Mostafa Bahaa	Phase 3
Unknown	Nutrition and Movement to Improve Quality of Life With Knee Osteoarthritis NCT05955300	St. Pölten University of Applied Sciences	N/A
Recruiting	ROSA Knee Intraoperative Planning Flexibility Study NCT05966519	Zimmer Biomet	—
Not Yet Recruiting	Improving Sleep After TKA Using Mirtazapine and Quetiapine NCT04728581	St. Anna Ziekenhuis, Geldrop, Netherlands	N/A
Recruiting	Optimizing Pain Self-Management in Total Knee Arthroplasty NCT06038240	University of Virginia	N/A
Recruiting	RFA or Chemical Neurolysis of the Genicular Nerves Compared to Conservative Treatment for Knee Pain Caused by NCT06094660	Dijklander Ziekenhuis	N/A
Completed	Evaluation of the Effect of Different Doses of Ozone Therapy on Pain and Function of Patients With Knee Osteoa NCT06088706	Ahmad Nazari	N/A
Unknown	Ultrasound Effect With Hyaluronate Injection on Risk of Fall in Geriatric Women With Knee Osteoarthritis NCT06078449	Badr University	N/A
Recruiting	Persistent Pain in Pharmacologically or Surgical Treated Osteoarthritis: Role of Mu-Limpho Marker NCT06637709	IRCCS San Raffaele Roma	—
Completed	A Study to Evaluate the Safety of Human Allogeneic Bone-Marrow-Derived Mesenchymal Stromal Cell Product Stroma NCT06084988	Cellcolabs Clinical SPV Limited	Phase 1 / Phase 2
Recruiting	MISHA Post-Market Clinical Study NCT06118892	Moximed	N/A
Completed	Effects of Retro-walking in Patients With Knee OA NCT06130774	Riphah International University	N/A
Completed	Hydrolyzed Collagen and Undenatured Collagen Type II in OA Knee NCT06229951	Prince of Songkla University	N/A
Completed	The Impact of Genicular Nerves Chemical Neurolysis on the Quality of Life of Patients with Advanced Knee Osteo NCT06087601	Poznan University of Medical Sciences	Phase 4
Recruiting	Use of a Putty as Gap Filler in Open-wedge Osteotomy NCT05992038	UMC Utrecht	N/A
Active Not Recruiting	Effects of Vitamin K on Lower-extremity Function in Adults With Osteoarthritis: NCT05505552	Tufts University	N/A
Unknown	Pain Phenotyping in Knee OA: a Pilot Trial NCT06066684	University Health Network, Toronto	—
Completed	Evaluation of the Relationship Between Muscle Architecture and Muscle Strength in Female Gonarthrosis Patients NCT06003413	Bezmialem Vakif University	—
Unknown	Health Coaching for Patients Waiting for Hip or Knee Replacements NCT06101875	Sheffield Hallam University	N/A
Completed	A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthrit NCT05931367	Eli Lilly and Company	Phase 3
Unknown	Characteristics of Hoffa Adipose Tissue and Intramuscular Adipose Tissue in the Quadriceps Muscle NCT05955976	Centre Hospitalier Universitaire de Nice	—
Recruiting	Gait Rehabilitation to Treat FastOA NCT05848622	University of North Carolina, Chapel Hill	N/A
Active Not Recruiting	Safety and Pharmacodynamics of GNSC-001 Intra-articular Injection for Knee Osteoarthritis NCT05835895	Genascence Corporation	Phase 1
Completed	The Effect of Single Task vs. Dual Task Assessment in Individuals With Knee Osteoarthritis NCT05893706	Istanbul Medipol University Hospital	—
Completed	Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to Osteoarthritis NCT05882812	ZetrOZ, Inc.	Phase 2
Completed	Cryo and Compression Therapy After TKA and UKA NCT05572359	Martini Hospital Groningen	N/A
Terminated	Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention Following an Acute Knee NCT05204836	University of Calgary	Phase 1
Unknown	"Ready-to-use" Intra-articular Formulation of Mesenchymal Stromal Cells NCT05751564	Universidad de los Andes, Chile	Phase 2
Terminated	Pregabalin for Central Sensitization in TKA NCT05460871	University of Iowa	Phase 4
Active Not Recruiting	Analgesic Potential of Light Therapy in Knee Osteoarthritis NCT05398666	Nova Scotia Health Authority	N/A
Unknown	Effectiveness of Physical Therapy in Stem Cell Transplant Recipients for Knee Osteoarthritis NCT05959902	Dow University of Health Sciences	N/A
Completed	Dry Cupping Therapy in Knee Osteoarthritis NCT04331158	Universidade Federal do Rio Grande do Norte	N/A
Completed	Clinical Efficacy and Safety of Loxacon Dietary Supplement Capsules at Patients With Knee Arthrosis NCT05925725	Polyclinic of the Hospitaller Brothers of St. John of God, Budapest	Phase 4
Completed	Energy Status and Protein Intake As Prognostic Indicators of Rehabilitative Outcomes NCT06734845	University of Connecticut	—
Recruiting	Effects of Fall Prevention Program on the Number of Falls Among Elderly Following Total Knee Replacement NCT05642260	Ministry of Health, Kuwait	N/A
Completed	Effectiveness of Pain Science Education in People With Symptomatic Knee Osteoarthritis NCT05649995	Marmara University	N/A
Unknown	Comprehensive Geriatric Assessment in Knee Osteoarthritis NCT05659979	University of Palermo	N/A
Completed	Microfragmented Adipose Tissue Compared to Corticosteroid Injection for the Treatment of Knee Osteoarthritis NCT05660772	Lipogems International spa	Phase 3
Unknown	The Effect of Semiconductor Knee Sleeves on Pain in Osteoarthritis of the Knee. NCT05255835	Herlev and Gentofte Hospital	N/A
Completed	Effect of Mulligans Mobilization With Movement in Osteoarthritis Knee. NCT05577403	Majmaah University	N/A
Recruiting	The Effect of Smart Ring Assisted Physiotherapeutic Intervention After TKR NCT05599776	Coxa, Hospital for Joint Replacement	N/A
Unknown	Comparing Local Anesthesia With and Without iPACK Block NCT04635176	University of Calgary	Phase 4
Unknown	Vapocoolant Spray Application During Intraarticular Knee Injection NCT05581433	Istanbul Rumeli University	N/A
Completed	Clinical Trial to Evaluate the Efficacy and Safety of LEVI-04 in Patients With Osteoarthritis of the Knee NCT05618782	Levicept	Phase 2
Completed	Efficacy of Duloxetine Compared to NSIADs in Osteoarthritis of Knee NCT05486026	Hawler Medical University	Phase 2
Unknown	OA Optimization Program Pilot Trial NCT05389371	University of Calgary	Phase 1 / Phase 2
Unknown	Exercise-related Irisin on Inflammation and Pain NCT05388994	Firat University	N/A
Unknown	Efficacy of Mesotherapy Added to Intra-articular Platelet-rich Plasma (PRP) in Patients With Knee Osteoarthrit NCT05329116	Necmettin Yildiz	N/A
Active Not Recruiting	Comparing Single Dose and Multiple Dose of Dexamethasone Post TKA NCT06339151	Thammasat University Hospital	N/A
Completed	A Study to Assess Efficacy of Supporting Properties and Safety of ARTNEO in Patients With Knee Osteoarthritis NCT06032442	NPO Petrovax	N/A
Withdrawn	Utilization of a Knee Brace With Extension Swing NCT05179044	NYU Langone Health	N/A
Recruiting	Geniculate Artery Embolization for Osteoarthritis NCT04456569	University of Minnesota	N/A
Completed	Evaluation of the Use of an E-health Therapeutic Education Application for Osteoarthritis Patients NCT04750304	University Hospital, Clermont-Ferrand	—
Unknown	RELIABILITY AND VALIDITY OF THE DT BALANCE TEST IN PATIENTS WITH TKA NCT06108466	Dokuz Eylul University	—
Completed	External Focus of Attention Posttraumatic Osteoarthritis NCT04922268	University of North Carolina, Charlotte	N/A
Completed	Understanding Ayurveda Disease Conditions and Treatment Responses NCT06167226	Ayurai Private Limited	—
Completed	An Effectiveness and Safety 6 Months Study of 3 Injections One Week Apart of SYNOLIS VA 40/80 in the Treatment NCT05829850	Aptissen SA	N/A
Completed	Adapting REhabilitation Delivery for Maximum Impact at Home NCT05164575	University of Alberta	N/A
Completed	Addition of Transcranial Direct Current Stimulation and Transcutaneous Electrical Nerve Stimulation to an Educ NCT05138471	Universidad de Murcia	N/A
Withdrawn	rTMS for Relieving Chronic OA Pain NCT05097729	Northwestern University	N/A
Completed	Muscle Strength and Total Knee Replacement NCT05248815	Vastra Gotaland Region	—
Unknown	HIGH AND LOW INTENSITY PROGRESSIVE RESISTED EXERCISES ON PAIN, RANGE OF MOTION AND FUNCTIONAL DISABILITY NCT05190380	University of Lahore	N/A
Completed	Effect of Pulsed Electromagnetic Field and Pulsed Ultrasound in Treating Knee Osteoarthritis NCT05151432	Horus University	N/A
Completed	Chronic Pain Master Protocol (CPMP): A Study of LY3526318 in Participants With Osteoarthritis NCT05080660	Eli Lilly and Company	Phase 2
Completed	Effect of Physical Therapy Modalities in Osteoarthritis NCT05089253	Majmaah University	N/A
Withdrawn	Group Education & Lifestyle Modification's Impact on Weight Loss & Quality Life of Patients with OA NCT04439019	Alberta Hip and Knee Clinic	N/A
Unknown	Biofeedback Retention in Individuals With AKA NCT05126485	San Jose State University	EARLY_Phase 1
Completed	The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study NCT04956393	University of British Columbia	N/A
Terminated	Effects of Sand Treatment on Osteoarthritis NCT03943303	University Vila Velha	N/A
Unknown	The Relationship Between Cannabis Use, Biomarkers, Tissue Cannabinoid Levels and Clinical Outcomes in Patients NCT04971629	University Health Network, Toronto	—
Completed	Melatonin Use After Primary Total Joint Arthroplasty NCT04795336	NYU Langone Health	Phase 1
Completed	pAF for the Treatment of Osteoarthritis NCT04886960	University of Utah	Phase 1 / Phase 2
Completed	Comparision of IPACK and Periarticular Block With Adductor Block Alone After Total Knee Artroplasty NCT04931966	Karaman Training and Research Hospital	N/A
Completed	Effects of Compression Mobilization in OA Patients NCT04944056	Mir Arif Hussain	N/A
Active Not Recruiting	The Technology, Exercise Programming, and Activity Prescription for Enhanced Mobility (TEAM) Study NCT04544904	Western University, Canada	N/A
Completed	Functionally Aligned vs Mechanical Axis Aligned Total Knee Arthroplasty NCT04748510	Perth Hip and Knee	N/A
Withdrawn	Study to Evaluate Resiniferatoxin in Patients With Knee Osteoarthritis Whose Total Knee Replacement Surgery is NCT04386980	Sorrento Therapeutics, Inc.	Phase 3
Completed	Comparison of Alignment Achieved Using the VELYS Robotic-Assisted Solution Versus Manual Instrumentation in To NCT04730271	DePuy Orthopaedics	N/A
Completed	Incorporating Patient-Reported Outcomes Into Shared Decision Making With Patients With Osteoarthritis of the H NCT04805554	University of Texas at Austin	N/A
Withdrawn	The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee Osteoarthritis NCT04767841	Sadat City University	Phase 1 / Phase 2
Completed	Robotic-assisted Total Knee Arthroplasty vs. Conventional One NCT04611815	Medical University of Warsaw	N/A
Completed	Efficacy of Cannabidiol in Knee Osteoarthritis NCT04607603	Medical University of Vienna	Phase 4
Unknown	High Intensity Laser Therapy (Classes IV) and Ibuprofen Gel Phonophoresis for Treating Knee Osteoarthritis NCT04320914	Maharishi Markendeswar University (Deemed to be University)	N/A
Active Not Recruiting	Robotized Navigation Compared to Conventional Technique in Total Knee Replacement NCT04525950	Haukeland University Hospital	N/A
Completed	Arthroscopic Evaluation of Cartilage Regeneration After Opening-wedge High Tibial Osteotomy NCT04541342	Assiut University	N/A
Completed	ROMTECH PortableConnect Rehabilitation Device Usage Post Unilateral Total Knee Arthroplasty (TKA) NCT04497129	ROM Technologies, INC	N/A
Completed	Home-based tDCS and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms NCT04375072	University of Arizona	N/A
Completed	Intraarticular Leukocyte-rich and Leukocyte-poor PRP for Osteoarthritis of the Knee NCT05737173	Queen Savang Vadhana Memorial Hospital, Thailand	Phase 2 / Phase 3
Unknown	Rehabilitation Exercise Using Digital Healthcare System in Patients With Total Knee Arthroplasty NCT04513353	Seoul National University Bundang Hospital	N/A
Terminated	Observational Study to Evaluate Clinical Performance and Safety in Total Knee Arthroplasty NCT04872855	Corin	—
Recruiting	Bone Marrow Aspirate Concentrate (BMAC)Treatment for Knee Osteoarthritis NCT04716803	University of California, San Diego	N/A
Completed	Safety and Efficacy of JointAlive™ on the Knee-joint Function in Adults With Knee Arthritis NCT04395547	Chenland Nutritionals Inc.	N/A
Unknown	Bone Marrow Versus Adipose Autologous Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis NCT04351932	Universidad Catolica Santiago de Guayaquil	Phase 3
Completed	Central Sensitization in Knee Osteoarthritis NCT04308967	Cukurova University	N/A
Unknown	High Versus Low Adductor Canal Block NCT04155983	Carilion Clinic	Phase 4
Completed	Effect of Combined Interventions on Pressure Pain Threshold NCT04312035	University of Pecs	N/A
Completed	Effects of Anti-gravity Treadmill Training on Knee Osteoarthritis in Geriatric Population. NCT04299568	Foundation University Islamabad	N/A
Completed	Reliability and Validity of Turkish Version of Knee Injury and Osteoarthritis Outcome Score-12 NCT04277676	Bahçeşehir University	—
Unknown	Kinematic- Versus Ligament-balanced Mechanical Alignment in TKA NCT04436211	Medical University of Graz	—
Completed	End-range Mobilization on Knee Osteoarthritis NCT04270253	University of Pecs	N/A
Recruiting	Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis NCT04238143	Healeon Medical Inc	N/A
Completed	Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy for Patients With Knee Osteoarthritis NCT04187092	University of Virginia	N/A
Terminated	Evaluation of Standard and Robot Assisted Total Knee Arthroplasty with a Bicrucatie Retaining Prosthesis NCT04334304	University Hospital, Ghent	N/A
Completed	Study of Pain Catastrophizing NCT03836586	University of Florida	N/A
Unknown	The Effect of Exercise Training on Balance and Functional Status in Individuals With Osteoarthritis' NCT04183933	Eastern Mediterranean University	N/A
Completed	Use of Interferential Current (IFC) Therapy After Total Knee Arthroplasty NCT04137731	Montefiore Medical Center	N/A
Active Not Recruiting	Pain & Aging: Combined Interventions for Fitness in the Community Study NCT04099394	University of Washington	N/A
Completed	Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis NCT04016272	Florida State University	N/A
Completed	Foot Wear Modification Along With Physical Therapy in Knee Osteoarthritis NCT04536519	Isra University	N/A
Unknown	Clinical and Radiographic Outcomes of Medial Open-wedge High Tibial Osteotomy NCT04036266	Assiut University	—
Terminated	MOTO Post-marketing Surveillance Study NCT04072055	Medacta International SA	—
Completed	Physiotherapy and Therapeutic Education on Patients With Pain Catastrophism Scheduled for a Total Knee Arthrop NCT03847324	University of Barcelona	N/A
Withdrawn	Conventional Platelet-Rich Plasma Versus Concentrated Bone Marrow Stem Cell Injections for Osteoarthritis of t NCT03271229	Mayo Clinic	Phase 2
Completed	Sustained Acoustic Medicine (SAM) Combined With a Diclofenac Ultrasound Coupling Patch for Knee Osteoarthritis NCT04391842	ZetrOZ, Inc.	Phase 1
Completed	Computer-Assisted Cryotherapy After Total Knee Arthroplasty NCT06730399	Martini Hospital Groningen	—
Completed	Self Cranial Electrical Stimulation (CES) for Pain in Older Adults With Knee Osteoarthritis (Self CES for Knee NCT04016259	The University of Texas Health Science Center, Houston	N/A
Completed	Strengthening Exercises Versus Proprioception and Balance Exercises in the Treatment of Knee Osteoarthritis NCT03893981	Istanbul University	N/A
Completed	Intra-articular Transplantation of Autologous Adipose Derived Stromal Vascular Faction (SVF) for Treatment of NCT03940950	Mayo Clinic	Phase 1
Unknown	Single Dose Adductor Canal Block vs SPANK Block for TKA NCT03502889	San Antonio Uniformed Services Health Education Consortium	N/A
Completed	Multi-modal Exercise Program in Older Aduls With Knee Osteoarthritis NCT03951506	Cardenal Herrera University	N/A
Completed	Colchicine for the Treatment of Osteoarthritis of the Knee NCT03913442	NYU Langone Health	Phase 4
Completed	Use of a Self-Guided Mindfulness Mobile Application to Improve Pain Outcomes in Individuals With Knee Osteoart NCT03936088	jilliansylvester	N/A
Withdrawn	Geniculate Artery Embolization for Knee Osteoarthritis NCT03835988	University of Calgary	N/A
Completed	The Validity, Reliability and Responsiveness of the Fullerton Advanced Balance Scale in Osteoarthritis NCT03728387	Eastern Mediterranean University	N/A
Completed	Femoral Cartilage Thickness In Patients With Lower Limb Amputation NCT04422717	Istanbul Physical Medicine Rehabilitation Training and Research Hospital	—
Withdrawn	Pain Control With Pre-operative Cryoneurolysis Following TKA NCT03818022	Fondren Orthopedic Group L.L.P.	N/A
Unknown	Role of Copper-Albumin Complex in Treatment of Knee Osteoarthritis in Human NCT03736109	Assiut University	—
Completed	Black Seed Oil in Treatment of Osteoarthritis NCT06029868	Ramsar international campus	N/A
Completed	Exercise Therapy in Combination With Central Nervous System-targeted Treatment for Osteoarthritis NCT03681613	University of Valencia	N/A
Completed	LLLT and Russian Electrical Stimulation in Osteoarthritis NCT04788706	University of Sao Paulo General Hospital	N/A
Completed	Mako Functionally Aligned Total Knee Arthroplasty vs Mako Mechanically Aligned Total Knee Arthroplasty NCT04092153	University College, London	N/A
Completed	Effect of Prebiotics on Function and Pain in Patients with Osteoarthritis and Obesity NCT04172688	University of Calgary	N/A
Unknown	Sharp Dissection Versus Monopolar Electrocautery in Primary Total Knee Arthroplasty Performed Under Tourniquet NCT03559478	Royal Infirmary of Edinburgh	N/A
Active Not Recruiting	Traditional Versus Alternative Alignment in TKR NCT03196011	Royal Devon and Exeter NHS Foundation Trust	N/A
Terminated	AIR (Artificial Implant for Medial Meniscus Replacement) Study NCT03696836	ATRO Medical B.V.	N/A
Completed	In Vivo Kinematics for Subjects Implanted With Klassic Total Knee Arthroplasty (TKA) NCT04113785	The University of Tennessee, Knoxville	—
Completed	Platelet Rich Plasma Versus Radio Frequency for Chronic Knee Arthritis NCT03886142	Assiut University	N/A
Completed	Power Production in Older Adults With Knee Osteoarthritis NCT03680807	KU Leuven	—
Completed	MRgFUS in the Treatment of Osteoarthritic Knee Pain NCT03453372	Istituto Ortopedico Rizzoli	N/A
Completed	Effect of LANCONONE in Weight-bearing Joint Pain NCT03658369	Vedic Lifesciences Pvt. Ltd.	N/A
Unknown	[Tc-99m]-RPI-087 as an Imaging Marker in Osteoarthritis of the Knee Compared to Healthy Volunteers NCT03503825	Reiley Pharmaceuticals Inc.	Phase 1
Completed	Comparing Surgical and Economical Parameters of Total Knee Replacement. NCT03427047	Medacta USA	N/A
Active Not Recruiting	Tibial and Femoral Components Migration and Adaptive Bone Remodeling After Insertion of Persona® TKA NCT03563131	Rigshospitalet, Denmark	N/A
Unknown	Knee Arthritis Treatment With Autologous Fragmented Adipose Tissue and PRP - Comparison of Two Treatment Metho NCT04321629	Rehasport Clinic	Phase 2
Recruiting	Balancing Kinematically Aligned Total Knee Replacements During Total Primary Knee Arthroplasty Using Verasense NCT03286868	Nova Scotia Health Authority	N/A
Completed	Euflexxa for the Treatment of Osteoarthritis NCT03459365	The Cleveland Clinic	N/A
Completed	Geniculate Artery Embolization for Knee Pain Secondary to Osteoarthritis (OA) NCT03362957	University of North Carolina, Chapel Hill	N/A
Unknown	Trial of Unicompartmental Versus Total Knee Arthroplasty NCT03385759	Anderson Orthopaedic Research Institute	N/A
Completed	Comprehensive Knee Osteoarthritis Index (CKOAI): Scale Development, Validation and Reliability Testing NCT03498833	Maharishi Markendeswar University (Deemed to be University)	N/A
Completed	The Use of Bone Growth Stimulators for Osteoarthritis of the Knee. NCT03476382	Coastal Carolinas Integrated Medicine	N/A
Completed	Independent Weight Loss Maintenance for Communities With Arthritis in North Carolina: the I-CAN Clinical Trial NCT03832296	Wake Forest University Health Sciences	N/A
Completed	Exercise on Knee OA With the Star Excursion Balance Test NCT03450486	Western University, Canada	N/A
Completed	Efficacy of Ipack Block and Surgeon's Joint Infiltration in Total Knee Arthroplasty NCT03653416	Icahn School of Medicine at Mount Sinai	Phase 4
Unknown	Cooled RF Lesion MRI Characteristics NCT03631030	International Spine, Pain and Performance Center	N/A
Completed	Cartilage Adaptation and Response to Interleukins and Exercise NCT03410745	Bispebjerg Hospital	N/A
Unknown	Semitendinosus Graft as Meniscal Transplant NCT04753424	Karolinska Institutet	—
Completed	The Effect of Prolonged Multimodal Analgesic Regimen on Post Hospital Discharge Opioid Use and Pain Control Af NCT04003350	Rothman Institute Orthopaedics	N/A
Completed	Dynamic Congruence Total Knee Replacement vs Posterior-stabilized NCT04524312	Medical University of Warsaw	N/A
Completed	Inflammation Impact on Pain in Knee Osteoarthritis NCT03389906	Sten Rasmussen, MD, PhD	N/A
Completed	A Multicentre Clinical Investigation to Assess Efficacy and Safety of Intra-articular Injections of Hyaluronic NCT04358120	Fidia Farmaceutici s.p.a.	N/A
Recruiting	RCT: Mako Medial Unicondylar Knee Arthroplasty vs Oxford Unicondylar Knee Arthroplasty NCT04095637	University College, London	N/A
Completed	Effects of Closed and Open Kinetic Chain Exercises NCT04186143	Hacettepe University	N/A
Completed	Effect of Implanting Allogenic Cytokines Derived From Human Amniotic Membrane (HAM) and Mesenchymal Stem Cells NCT03337243	Sport and Spine Rehab Clinical Research Foundation	N/A
Completed	Development of an Osteoarthritis (OA) Care Plan to Improve Process and Quality of OA Treatment Decisions NCT03102580	University of Massachusetts, Worcester	N/A
Completed	Effects of Motor Imagery Intervention on Functional Recovery Following Total Knee Arthroplasty NCT03684148	Science and Research Centre Koper	N/A
Completed	Epidural Analgesia vs Adductor Canal Block in Bilateral TKA NCT03205540	Mahidol University	N/A
Completed	Meditation and Opioid Consumption in Total Joint Replacement Patients Undergo Primary Total Hip and Knee Repla NCT05669066	Beth Israel Deaconess Medical Center	N/A
Completed	Prospective Observational Study of Pain Evolution in Patients With Primary Knee Osteoarthritis Treated With Pr NCT04196764	Procare Health Iberia S.L.	—
Completed	Novel Pre-Surgery Exercise-Conditioning in Patients Waiting for Total Knee Arthroplasty (TKA) NCT03113032	Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust	N/A
Completed	Intra-articular Injection of Allogenic Lyophilized Growth Factors in Primary Knee Osteoarthritis NCT04331327	Rasmia Elgohary	Phase 2
Completed	A Retrospective Study to Evaluate the ConforMIS iTotal® Posterior Stabilized (PS) Knee Replacement System NCT03289000	Restor3D	—
Unknown	Prospective Post Approval Clinical Follow-Up Study of the Commercially Available U2 Knee™ System - "U-Propel S NCT03060057	United Orthopedic Corporation	—
Completed	A Study to Evaluate the Analgesic Efficacy and Safety of V120083 in Subjects With Osteoarthritis (OA) of the K NCT03028870	Purdue Pharma LP	Phase 2
Terminated	Study to Evaluate Long Term Performance and Safety of the Knee Prosthesis (HLS KneeTec Deep Dish) NCT05211141	Corin	—
Completed	Kinematic Alignment Compared to Mechanical Alignment Techniques for Total Knee Replacement Surgery (KARMA) NCT03994250	Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust	N/A
Completed	Zingiber and Acmella Against Knee Osteoarthritis NCT03907787	Azienda di Servizi alla Persona di Pavia	N/A
Completed	Long-Duration Ultrasound for Knee Osteoarthritis NCT03800927	ZetrOZ, Inc.	N/A
Completed	Protein Turnover in the Osteoarthritic Knee NCT03037294	Maastricht University Medical Center	N/A
Completed	Platelet Rich Plasma for Knee Osteoarthritis NCT03197441	Pei-Yuan Lee, MD	N/A
Completed	Injection of Autologous Adipose Tissue for Treatment of Osteoarthritis in the Knee NCT03399630	Aestique Medical Center	N/A
Unknown	Post-op Ketamine Study NCT03865550	Rothman Institute Orthopaedics	N/A
Completed	Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty NCT03395990	Duke University	N/A
Completed	WHIRLPOOL FOR OSTEOARHRITIS NCT03299114	Ufuk University	N/A
Completed	Tranexamic Acid in Total Knee Replacement NCT03656445	Democritus University of Thrace	N/A
Completed	Effectiveness of Five Intraarticular Strategies on Knee Osteoarthritis NCT03783455	Maimónides Biomedical Research Institute of Córdoba	N/A
Completed	A Study on the Use of Tourniquet Use In Primary Total Knee Arthroplasty NCT04502459	The University of Hong Kong	N/A
Completed	The Need for Compression Bandage Following Total Knee Arthroplasty A Prospective Randomized Controlled Trial C NCT03521869	Rothman Institute Orthopaedics	N/A
Unknown	Joint Loading vs Normal Physiotherapy Care in Degenerative Knees (V1) NCT02454374	Leeds Comunity Healthcare NHS Trust	N/A
Completed	Anterior Knee Pain Between Unisex Knee Prosthesis VS Gender Specific Knee Prosthesis Following MIS TKA NCT05045651	Thammasat University	N/A
Completed	Radiofrequency Neurotomy In Relieving Chronic Knee Pain NCT03224637	Assiut University	N/A
Completed	Are Perception of Pain and Psychological Distress Before Knee Arthroplasty Associated With Reason for Revision NCT05105646	Leiden University Medical Center	—
Completed	Surgical Excision of the Fat Pad NCT04503512	Liverpool University Hospitals NHS Foundation Trust	N/A
Terminated	Open Label Study to Collect Clinical Data to Document Clinical Performance and Safety in Total Knee Arthroplas NCT04727060	Corin	—
Terminated	LEGION™ Primary Safety and Efficacy NCT04040985	Smith & Nephew, Inc.	N/A
No Longer Available	Individual Patient Expanded Access IND of Autologous HB-adMSCS for the Treatment of Bilateral Knee Pain. NCT04604288	Hope Biosciences Research Foundation	—
No Longer Available	Study of the Effects of Photobiomodulation in Patients With Osteoarthritis NCT03924128	University of Sao Paulo	—