NCT03940950

Intra-articular Transplantation of Autologous Adipose Derived Stromal Vascular Faction (SVF) for Treatment of Osteoarthritis of the Knee

Safety and Feasibility of Intra-articular Transplantation of Autologous Adipose Derived Stromal Vascular Faction (SVF) for Treatment of Osteoarthritis of the Knee

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 40 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Researchers are trying to determine the safety and feasibility of autologous, adipose derived stromal vascular fraction injections in the treatment of knee osteoarthritis

Conditions

• Osteo Arthritis Knee
• Degenerative Joint Disease of Knee

Interventions

Type	Name	Description
BIOLOGICAL	Autologous Adipose-Derived SVF (Stromal Vascular Fraction)	60 ml of fat is collected from subjects abdominal wall and SVF is removed from the fat. The SVF is injected into the knee through a needle.
DRUG	Placebo	Saline control that contains no active ingredient

Timeline

• Start date: 2019-07-02
• Primary completion: 2025-05-05
• Completion: 2025-05-23
• First posted: 2019-05-07
• Last updated: 2026-01-27

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study