NCT04095637

RCT: Mako Medial Unicondylar Knee Arthroplasty vs Oxford Unicondylar Knee Arthroplasty

A Prospective Randomised Control Trial of Mako Medial Unicondylar Knee Arthroplasty Versus Jig-based Oxford Unicompartmental Knee Arthroplasty With Navigation Contro

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 140 (estimated)
• Sponsor: University College, London · Academic / Other
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The overall aim of this prospective, randomised, single-blinded, controlled trial is to compare clinical outcomes and accuracy of implant positioning in Mako robotic UKA versus jig-based Oxford UKA with navigation control. Patients receiving the Mako robotic UKA (Stryker Ltd) will form the investigation group and those undergoing the jig-based Oxford UKA (Zimmer-Biomet Ltd) with navigation control will form the control group. The primary objective in this study is to compare accuracy of component positioning as assessed by postoperative low radiation dose CT scan between conventional Jig-based Oxford UKA with navigation control and Mako robotic UKA.

Conditions

• Unicompartmental Knee Replacement
• Osteo Arthritis Knee
• Surgery

Interventions

Type	Name	Description
DEVICE	Medial knee arthroplasty	Surgical intervention where the medial portion of the knee is replaced by an artificial metal and polyethylene implant

Timeline

• Start date: 2017-11-24
• Primary completion: 2025-12-31
• Completion: 2026-01-01
• First posted: 2019-09-19
• Last updated: 2025-07-09

Locations

1 site across 1 country: United Kingdom

Regulatory

• FDA-regulated device study