NCT05737173

Intraarticular Leukocyte-rich and Leukocyte-poor PRP for Osteoarthritis of the Knee

Comparison Efficacy of Intraarticular Knee Injection in Knee Osteoarthritis With Leukocyte-rich and Leukocyte-poor Platelet-rich Plasma

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 93 (actual)
• Sponsor: Queen Savang Vadhana Memorial Hospital, Thailand · Academic / Other
• Sex: All
• Age: 50 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

To compare the efficacy of intraarticular knee injection between leukocyte-rich and leukocyte-poor platelet-rich plasma in knee osteoarthritis treatment

Detailed description

Participants were randomized into 3 groups (leukocyte-rich platelet-rich plasma (LR-PRP), leukocyte-poor platelet-rich plasma (LP-PRP), and Corticosteroid (CS)). The primary outcome of this study is The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and was measured pre-treatment and post-treatment at follow-up at 1, 3, and 6 months

Conditions

• Osteo Arthritis Knee

Interventions

Type	Name	Description
DRUG	Leukocyte-rich platelet-rich plasma	Intra-articular knee injection
DRUG	Leukocyte-poor platelet-rich plasma	Intra-articular knee injection
DRUG	Corticosteroid	Intra-articular knee injection

Timeline

• Start date: 2020-08-03
• Primary completion: 2022-09-01
• Completion: 2022-10-01
• First posted: 2023-02-21
• Last updated: 2023-02-21

Locations

1 site across 1 country: Thailand