| Enrolling By Invitation | ThyMoves: Screening and Exercise to Improve Muscle, Enhance Quality of Life, and Reduce Fall Risk in Thyroid D NCT06960005 | Aalborg University Hospital | N/A |
| Not Yet Recruiting | Walking for Hypothyroidism Trial (WHT) NCT07205042 | University of Karachi | N/A |
| Recruiting | Gluten Free Diet in Hashimoto's Hypothyroidism NCT07060118 | The Cleveland Clinic | N/A |
| Recruiting | Periodization Resistance Training on Quality of Life in Females With Hypothyroidism NCT06757712 | Cairo University | N/A |
| Recruiting | Patient-centered Dosage of Levothyroxine NCT06455371 | University Hospital of North Norway | N/A |
| Recruiting | Novel Approaches to the Treatment of Hypothyroidism NCT06731764 | UConn Health | Phase 2 / Phase 3 |
| Recruiting | Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing NCT06629272 | University of Michigan | N/A |
| Active Not Recruiting | Clinical Efficacy of Darqeen Capsule for the Management of Hypothyroidism Associated with Female Reproductive NCT06826248 | Hamdard University | EARLY_Phase 1 |
| Recruiting | SNUH Immune Checkpoint Inhibitor-induced Hypothyroidism Recovery Trial NCT07421869 | Seoul National University Bundang Hospital | N/A |
| Enrolling By Invitation | Efficacy and Safety of Catheter Ablation of Atrial Fibrillation in Patients With Thyroid Hormone Stabilization NCT06452823 | The Second Affiliated Hospital of Jiaxing University | — |
| Recruiting | A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of NCT06345339 | AbbVie | Phase 2 / Phase 3 |
| Recruiting | Interventional Study to Improve Medication Adherence Using Patient Decision Aid NCT06205303 | SingHealth Polyclinics | N/A |
| Recruiting | Dosing of LT4 in Older Individuals NCT06073665 | University of Pennsylvania | Phase 4 |
| Unknown | Throid Dysfunction in Liver Failure and Its Eddects Upon Outcome NCT06179368 | Assiut University | — |
| Unknown | Effect of Life Style Modification and Metformin on Hypothyroidism With Insulin Resistance NCT06096454 | Assiut University | Phase 4 |
| Unknown | Effect of Vitamin C Supplementation in Patients With Primary Hypothyroidism NCT05733078 | Dr Adnan Agha | Phase 2 |
| Unknown | The Effects of an Anti-inflammatory Diet With or Without Curcumin Supplementation on Anthropometric Measuremen NCT05975866 | National Nutrition and Food Technology Institute | N/A |
| Recruiting | Comorbidities Resolution After MGB Surgery and Change in Body Composition NCT06015620 | All India Institute of Medical Sciences, Bhubaneswar | — |
| Unknown | Awareness of Osteoporosis in Patients With Hypothyroidism NCT05760131 | Uskudar State Hospital | — |
| Completed | Effect of Brain GABA Metabolite Amount to Propofol Utilisation Under TIVA in Hypothyroid Patient NCT06649318 | Duzce University | — |
| Completed | Study of XP-8121 For the Treatment of Adult Subjects With Hypothyroidism NCT05823012 | Xeris Pharmaceuticals | Phase 2 |
| Completed | A Study Evaluation the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyr NCT05712421 | Neuvosyn Laboratories, LLC | Phase 2 |
| Unknown | The Effect of Mobile Application on Hypothyroid Patients NCT05708456 | Sakarya University | N/A |
| Unknown | Early Detection of Endolymphatic Hydrops in Hypothyroid Patients NCT05334771 | Assiut University | — |
| Recruiting | Improvement of Laboratory Diagnostics in Hypothyroid Patients Using Levothyroxine NCT06083636 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Unknown | Individual Dosing of Levothyroxine After Thyroidectomy NCT05240911 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Completed | A Study Evaluating the Safety and Efficacy of Hormone Replacement Therapy With ST-1891 Compared to Levothyroxi NCT05412979 | Sention Therapeutics, LLC | Phase 2 |
| Completed | Pharmacist Role in Thyroid Disorders NCT06408909 | Istanbul University - Cerrahpasa | N/A |
| Unknown | Timing of Thyroxine Dose In Ramadan NCT05421468 | King Abdullah International Medical Research Center | N/A |
| Withdrawn | Pediatric Risk of Hypothyroidism With Iodinated Contrast Media NCT03631771 | GE Healthcare | Phase 4 |
| Unknown | Quality of Life Among Egyptian Hypothyroid Patients NCT05143918 | Assiut University | — |
| Recruiting | Evaluation of Different Diagnostic Therapeutic Strategies in Patients with Thyroid Pathology NCT06779747 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Enrolling By Invitation | Quest to Analyze One Thousand Humans Meditating NCT06583395 | Tobias Moeller-Bertram | — |
| Unknown | Type 2 Deiodinase Gene Polymorphism and the Treatment of Hypothyroidism Caused by Thyroidectomy in Thyroid Can NCT05247476 | Zhongshan Hospital Xiamen University | Phase 4 |
| Completed | The Relationship Between Serum rT3 Concentrations, T3/T4 Ratio, and Symptoms/Quality of Life in Treated Hypoth NCT05015725 | Semmelweis University | — |
| Recruiting | Hypothyroidism After the TAVI Procedure in Elderly Patients NCT04831957 | Universitair Ziekenhuis Brussel | N/A |
| Recruiting | Register for Patients With Thyroid Hormone Resistance. NCT06566066 | Charite University, Berlin, Germany | — |
| Terminated | Comparison of Levothyroxine Formulation in Hypothyroid Patients With Enteral Feeding NCT04878614 | University of California, Los Angeles | Phase 4 |
| Completed | Normal Range of TSH and FT4 in Pregnancy NCT04860622 | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | — |
| Completed | Long-Term Efficacy and Safety of Once-Weekly Levothyroxine Regimen in Hypothyroid Patients NCT07133295 | Sohag University | — |
| Completed | Effect of Exercise on Irisin Levels of Hypothyroid Rats NCT06699069 | Riphah International University | N/A |
| Completed | The Impact of Pituitary-thyroid and Pituitary-adrenal Axes Function on COVID-19 Clinical Course. NCT05070091 | Medical University of Gdansk | — |
| Terminated | Use of Liquid Stable Levothyroxine in Trisomy 21 Pediatric Patients NCT04747275 | Children's Mercy Hospital Kansas City | Phase 4 |
| Unknown | Biosignals by Wearables in Thyroid Dysfunction NCT04806269 | Seoul National University Bundang Hospital | — |
| Unknown | A Study to Determine the Validity and Sensitivity of 'Questionnaire to Screen for HYpothyroidism' (Q'SHY) NCT04784208 | Abbott | — |
| Completed | Analysis of BPA Concentration in Serum in Women of Reproductive Age With Autoimmune Thyroid Disease NCT04682340 | Jagiellonian University | — |
| Unknown | Correlation Between Thyroid Function and Quality of Life in Hypothyroidism NCT04795947 | Beijing Chao Yang Hospital | — |
| Completed | Energy Metabolism in Thyroidectomized Patients NCT04782856 | Virginia Commonwealth University | Phase 2 |
| Recruiting | A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients NCT03977207 | University of California, Irvine | N/A |
| Completed | Higher Levothyroxine Requirements After Right-side Hemithyroidectomy NCT04648722 | Medical University of Vienna | — |
| Completed | Fetal and Neonatal Thyroid in Pregnancies With Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS- COV2 ) NCT05385029 | OMER B ABDELBASIT | — |
| Unknown | REduction of LEvothyroxine in Adults; a SElf Controlled Study NCT05821881 | Leiden University Medical Center | — |
| Unknown | The Impact of Subclinical Hypothyroidism on Cardiovascular System NCT04236232 | Assiut University | — |
| Completed | A Study of Armour® Thyroid Compared to Synthetic T4 (Levothyroxine) in Previously Hypothyroid Participants NCT04124705 | Allergan | Phase 2 |
| Completed | Biosignals by Wearable Devices in Hypothyroidism NCT04332770 | Seoul National University Bundang Hospital | — |
| Completed | Variations in the DIO2 and MCT10 Genes and Effect of Triiodothyronine Treatment NCT03926585 | Birte Nygaard | — |
| Terminated | Thyroid Function of Pediatric Subjects Following Isovue® Administration NCT03779906 | Bracco Diagnostics, Inc | Phase 4 |
| Recruiting | The Protection of Thyroid Function in IMRT for Nasopharyngeal Carcinoma NCT06268600 | Jiangxi Provincial Cancer Hospital | N/A |
| Completed | Metabolomics of Thyroid Hormones NCT03823859 | University Hospital, Basel, Switzerland | — |
| Unknown | Upper Limit for TSH of First and Second Trimester Pregnancy in Turkey NCT03754621 | Bartin State Hospital | — |
| Completed | Identification of Non-responders to Levothyroxine Therapy NCT03627611 | Oslo University Hospital | Phase 2 |
| Completed | Establishing RIs for TSH in Children Under the Age of Two Years NCT04877665 | Aga Khan University Hospital, Pakistan | — |
| Completed | Hypothyroidism Treated With Calcitonin NCT03342001 | University of Maryland, Baltimore | Phase 4 |
| Unknown | Hypothyroidism With Congenital Heart Disease (CHD) NCT03496363 | Assiut University | — |
| Completed | A Prospective Study of Hypothyroidism After Radiotherapy for Breast Cancer NCT04528225 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | — |
| Completed | Improving White Matter Integrity With Thyroid Hormone NCT04098991 | University of Illinois at Chicago | — |
| Unknown | Hypothyroidism in Patients With Type 1 Diabetes NCT03257566 | Assiut University | — |
| Completed | The Effect of Aroma on Fatigue Scores Among Women With Hypothyroidism NCT03465176 | Nutraceuticals Research Institute | N/A |
| Completed | Combined Replacement Therapy With Levothyroxine and Liothyronine in Thyroidectomized Patients NCT03053115 | Azienda USL Modena | Phase 2 / Phase 3 |
| Completed | Effect of Levothyroxine on Serum Adiponectin, Insulin Resistance and Cardiovascular Risk in Patients With Hypo NCT02467244 | All India Institute of Medical Sciences, Bhubaneswar | — |
| Completed | Comparing Two-time Points of Thyroid Hormone Replacement During the Holy Month of Ramadan NCT03988517 | Hamad Medical Corporation | N/A |
| Terminated | Is Levothyroxine Alone Adequate Thyroid Hormone Replacement? NCT02567877 | University of Colorado, Denver | — |
| Completed | Iodinated Contrast Agents and Risk of Hypothyroidism in Young Children in the United States NCT02959827 | Bayer | — |
| Completed | TSHβX1 and D2 THR92ALA in Pregnancy NCT03612908 | Materno-Perinatal Hospital of the State of Mexico | — |
| Completed | Observational Study on Hypothyroidism in Young Children Following Iodine Contrast Exposure NCT02766283 | Bayer | — |
| Completed | Management of Patients With Diagnosis of Hypothyroidism, as Hospitalized and as Outpatients, in Internal Medic NCT05314790 | Fadoi Foundation, Italy | — |
| Unknown | Randomized Crossover Trial for the Evaluation of the Possible Effects in the Intestine of Two Different Pharma NCT02917863 | Meyer Children's Hospital IRCCS | Phase 4 |
| Withdrawn | Mean Percentage of Levothyroxine Dosage Increase in Patients With Hypothyroidism Started on Enteral Feeding NCT02577367 | Jocelyne Karam | Phase 4 |
| Unknown | Thyroid Hormone Replacement for Hypothyroidism and Acute Myocardial Infarction(ThyroHeart-AMI) NCT02512978 | Chinese Academy of Medical Sciences, Fuwai Hospital | Phase 4 |
| Completed | Hypothyroidism, Metabolism and Food Intake NCT02993562 | Herlev Hospital | — |
| Withdrawn | Levothyroxine Treatment for Subclinical Hypothyroidism After Head and Neck Surgery NCT02548715 | University of Alberta | Phase 2 / Phase 3 |
| Completed | Evaluation of the Effects of Teleconsultations on a Endocrinology Referral List NCT02710799 | Hospital de Clinicas de Porto Alegre | N/A |
| Unknown | Desiccated Thyroid Extract Versus Synthetic T3/T4 Combination (ThyrolarTM) Versus L-T4 Alone in the Therapy of NCT02317926 | Walter Reed National Military Medical Center | N/A |
| Completed | Hypothyroidism, Metabolism and Quality of Life - Focus on QOL, REE, Cognitive Function and Body Composition NCT02891668 | Herlev Hospital | — |
| Completed | Effect of Hypothyroidism on Brown Adipose Tissue NCT02364102 | University Hospital, Basel, Switzerland | — |
| Completed | Vitamin D, Iodine, and Lead Levels in Haitian Infants and Children. NCT02301520 | Boston Children's Hospital | — |
| Completed | Iodine Status of Preschoolers Given Micronutrient Powder for 6 Months NCT02280330 | Nutrition Center of the Philippines | Phase 4 |
| Completed | Thyroid Disorders in Malaysia: A Nationwide Multicentre Study NCT02190214 | International Islamic University Malaysia | — |
| Completed | Monitoring and Evaluation of the Levothyroxin Replacement Therapy in Pregnant Women With Hypothyroidism NCT02094079 | Birte Nygaard | — |
| Withdrawn | Post Partum Thyroiditis 2: Long Term Observations NCT00287144 | Sykehuset Telemark | — |
| Completed | Interaction Between Levothyroxine and Probiotics in Hypothyroid Patients NCT03095963 | Azienda USL Modena | N/A |
| Completed | Study to Verify Clinical Utility of Point-of-Care (POC) Thyroid Stimulating Hormone (TSH) Test Kits as Compare NCT01921452 | Merck KGaA, Darmstadt, Germany | Phase 4 |
| Unknown | Effects of L-thyroxine Replacement on Serum Lipid and Atherosclerosis in Hypothyroidism NCT01848171 | Shandong Provincial Hospital | Phase 4 |
| Completed | Study of Dose Adjustment From Levothyroxine to a New Levothyroxine Sodium Test Formulation NCT01916304 | Takeda | Phase 2 |
| Unknown | Effect of L-Thyroxine on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidism NCT01831869 | Shandong Provincial Hospital | Phase 4 |
| Completed | A Study of T3 Therapy in Patients With Hypothyroidism NCT01800617 | Ipe, LLC | Phase 2 |
| Withdrawn | Effects of Thyroid Hormone Enzyme Blocking on Hypothyroidism NCT01801033 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Completed | Non-immune Related Hypothyroidism in Iodine Sufficient Area NCT03180892 | Samsung Medical Center | — |
| Withdrawn | The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid Carcinoma NCT01707056 | Medstar Health Research Institute | N/A |
| Completed | Study of Optimal Replacement of Thyroxine in the Elderly NCT01647750 | Newcastle-upon-Tyne Hospitals NHS Trust | Phase 4 |
| Completed | Effects of L-carnitine on Hypothyroidism NCT01769157 | Korea University Anam Hospital | Phase 4 |
| Unknown | Effects of Thyroid Hormone Withdrawal on Metabolic Parameters During Radioactive Iodine Therapy in Thyroid Can NCT01744769 | Konkuk University Medical Center | — |
| Completed | Detection of Celiac Disease in Patients With Hypothyroidism NCT01862510 | University of Vermont | — |
| Completed | Brown Adipose Tissue Activity and Thyroid Hormone NCT02499471 | Maastricht University Medical Center | N/A |
| Completed | Validation of a New TSH Test NCT01997554 | Hospices Civils de Lyon | N/A |
| Completed | Bone Structure and Strength Evaluated by Extreme-CT Scan Before and After Treatment of Hyper- and Hypothyroidi NCT02005250 | Steen Bonnema | — |
| Completed | Bioequivalence of Two Levothyroxine Tablet Formulations in Healthy Indian Volunteers NCT01536678 | GlaxoSmithKline | Phase 4 |
| Unknown | Thyroid Study Type 2 Diabetes Mellitus (T2DM) NCT01379170 | Maastricht University Medical Center | Phase 4 |
| Unknown | ThyrOp: A Study of Individual Subclinical Hypothyroidism After Hemithyroidectomy for Benign Nontoxic Goiter NCT01358136 | Naestved Hospital | — |
| Unknown | Preconceptional Thyroid Screening and Childhood Nerocognitive Function NCT01744743 | Fudan University | N/A |
| Completed | The Yield of Postnatal Thyroid Function Test in the Well Baby Nursery NCT05033496 | Hillel Yaffe Medical Center | — |
| Unknown | NOMOTHETICOS: Nonlinear Modelling of Thyroid Hormones' Effect on Thyrotropin Incretion in Confirmed Open-loop NCT01145040 | Ruhr University of Bochum | — |
| Unknown | Study of an Intervention to Improve Problem List Accuracy and Use NCT01105923 | Brigham and Women's Hospital | N/A |
| Terminated | Insulin Sensitivity and Metabolism Before and After Treatment in Patients With Hypothyroidism NCT00770016 | University of Aarhus | N/A |
| Completed | MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use NCT01050465 | University of Missouri-Columbia | N/A |
| Completed | Observational Study With Prospective and/or Retrospective Follow-up, Without Modifying Patient Treatment and F NCT01197183 | Merck KGaA, Darmstadt, Germany | — |
| Completed | Neurocognitive and Metabolic Effects of Mild Hypothyroidism NCT00565864 | Oregon Health and Science University | Phase 4 |
| Completed | Maternal Hypothyroidism in Pregnancy NCT00818896 | Women and Infants Hospital of Rhode Island | — |
| Completed | Post-radiation Hypothyroidism After IMRT for Nasopharyngeal Carcinoma NCT02689609 | The University of Hong Kong | — |
| Unknown | The Prospective Study of Standard Treatment of Graves Disease Iodine 131 and Prevention of Adverse Reactions NCT01204359 | Sun Yat-sen University | Phase 3 |
| Recruiting | Thyroid Function and Structure in Klinefelter Syndrome NCT05581147 | University of Roma La Sapienza | — |
| Completed | Generic vs. Name-Brand Levothyroxine NCT00403390 | Boston Children's Hospital | N/A |
| Completed | Thyroid Dysfunction in Women With Newly Diagnosed Breast Cancer Compared to Healthy Volunteers NCT00336102 | University of South Florida | — |
| Terminated | Combined Levothyroxine/Liothyronine Supplementation in Hypothyroid Patients With Brain Tumors NCT00488644 | M.D. Anderson Cancer Center | N/A |
| Completed | TSH Receptor Mutations Among a Consanguineous Community NCT00747760 | HaEmek Medical Center, Israel | — |
| Completed | Thyroid Hormone Dose Adjustment in Pregnancy NCT00230802 | Brigham and Women's Hospital | N/A |
| Completed | Subclinical Thyroid Dysfunction and Risk of Myocardial Infarction and Stroke NCT00094237 | University of North Carolina, Chapel Hill | — |
| Completed | Metabolic Changes in Hypothyroid Patients NCT00524238 | University of Aarhus | N/A |
| Terminated | Growth Hormone and GnRH Agonist in Adolescents With Acquired Hypothyroidism NCT00206375 | Baylor College of Medicine | Phase 4 |
| Unknown | Thyroxine Titration Study NCT00111735 | Sir Charles Gairdner Hospital | Phase 4 |
| Completed | Swallowing Function Before and After Surgery for Thyroid Goiter NCT00205348 | University of Wisconsin, Madison | — |
| Completed | Combined Therapy With L-Thyroxine and L-Triiodothyronine Compared to L-Thyroxine Alone NCT00715572 | I.M. Sechenov First Moscow State Medical University | N/A |
| Completed | Study of Radioiodine (131-I) Uptake Following Administration of Thyrogen and Hypothyroid States During Thyroid NCT00001730 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 4 |
| Completed | Immunogenetic Factors of Coronary Heart Disease NCT00005184 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Recruiting | Natural History of Thyroid Function Disorders NCT00001159 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |