Trials / Unknown
UnknownNCT01831869
Effect of L-Thyroxine on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidism
The Beneficial Effect of L-Thyroxine Long -Term Replacement on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidism: A Prospective Study
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 400 (estimated)
- Sponsor
- Shandong Provincial Hospital · Other Government
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
Subclinical hypothyroidism (SCH) is a common condition affecting 3-10% of the general population, especially in women older than 50 years old. It is controversial whether SCH can lead to increased risks of cardiovascular (CV) disease and whether treatment with L-thyroxine reverses these risks. The present study was designed to evaluate the effect of L-thyroxine treatment in SCH on lipid profile, atherosclerosis, endothelial function, serum inflammatory factors and adipocytokines.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | L-thyroxine |
Timeline
- Start date
- 2013-04-01
- Primary completion
- 2022-04-01
- Completion
- 2022-04-01
- First posted
- 2013-04-15
- Last updated
- 2018-09-12
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT01831869. Inclusion in this directory is not an endorsement.