Clinical Trials Directory

Trials / Conditions / Heart Valve Diseases

Heart Valve Diseases

160 registered clinical trials studyying Heart Valve Diseases33 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingVDyne Transcatheter Tricuspid Valve Replacement Study to Evaluate Safety and Clinical Efficacy in Patients Wit
NCT07516444
VDyne, Inc.N/A
Not Yet RecruitingAI Assisted Screening for VHD Using Routine Chest CT Scans
NCT07449130
Second Affiliated Hospital, School of Medicine, Zhejiang University
RecruitingGLS in Difficult CPB Weaning
NCT07390903
Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Not Yet RecruitingPostoperative Intravenous Ferric Derisomaltose for Prevention of Long-term Anemia After Cardiac Surgery
NCT07238972
Yonsei UniversityPhase 4
CompletedEffective Myocardial Protection Time of Del Nido Cardioplegia in Adult Cardiac Surgery
NCT07249424
Muhammet Talha Ceran, MD
CompletedEffect of Virtual Reality and Binaural Beat on Sleep and Comfort in Adults After Mechanical Valve Replacement
NCT07365488
University of BaghdadN/A
Not Yet RecruitingKorea VHD Echo Study: Surveillance of Aortic, Mitral & Tricuspid Patients - Insights From Real-world Practice
NCT07068633
Yonsei University
Active Not RecruitingPaired-Ring Mitral Annuloplasty Ring Sizing Device
NCT06965725
Endeavor Health
RecruitingEffect of Losartan on the Neurohumoral Axis and Ventricular Remodeling of Patients With Severe Aortic Regurgit
NCT07099859
Vitor Emer Egypto RosaPhase 4
Not Yet RecruitingAn Exploratory Clinical Study to Evaluate the Safety and Efficacy of a Cardiac Surgical Cryoablation System fo
NCT06703528
China National Center for Cardiovascular Diseases
RecruitingAntagonization of Heparin With Protamine Sulfate After TAVI
NCT06215378
Assistance Publique - Hôpitaux de ParisPhase 3
Not Yet RecruitingMulticentre Clinical Study of Ultra-Fast-Track Anaesthesia for Minimally Invasive Heart Valve Surgery
NCT06541483
Zhejiang Provincial People's HospitalN/A
RecruitingEchocardiography in Nursing Home
NCT06445231
Nantes University HospitalN/A
RecruitingReal World European Investigation of Safety and Clinical Efficacy of the EVOQUE System (TRISCEND III EU)
NCT06569602
Edwards Lifesciences
RecruitingThe TRICURE EFS Study
NCT06506942
TRiCaresN/A
Not Yet RecruitingPsoas Muscle Index (PMI) as a Predictor of Outcomes After Minimally Invasive Cardiac Surgery
NCT06571643
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
RecruitingEFS of the DUO System for Tricuspid Regurgitation
NCT05913908
CroiValve LimitedN/A
RecruitingCardiopulmonary Rehabilitation In Heart Valve Surgery
NCT06493123
Istanbul Saglik Bilimleri UniversityN/A
Enrolling By InvitationENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation
NCT05932615
Abbott Medical DevicesN/A
UnknownCardiac Rehabilitation for Young People
NCT05968521
Greater Manchester Mental Health NHS Foundation TrustN/A
RecruitingEuropean Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study
NCT06235385
Assistance Publique - Hôpitaux de Paris
RecruitingStudy of Health Behavior in Patients After Heart Valve Replacement: Longitudinal Studies
NCT06490952
Fujian Medical University Union Hospital
RecruitingTo Investigate the Effect of Esketamine Hydrochloride on Pulmonary Complications
NCT06467513
Zhang XIao MeiPhase 4
RecruitingMCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
NCT05933083
University of California, San FranciscoN/A
Active Not RecruitingTriple Cardiovascular Disease Detection With an Artificial Intelligence-enabled Stethoscope
NCT05987670
Imperial College LondonN/A
UnknownSpectroscopic Assessment of Intramyocardial Oxygen Saturation During Open-Heart Surgery
NCT06084091
Spectrocor
RecruitingPROMISE: Percutaneous peRipheral cannulatiOn for Minimally-InvaSive Heart Valve surgEry
NCT05961150
Universitätsklinikum Hamburg-Eppendorf
Active Not RecruitingEvaluation of the Viability and Safety of Early Discharge Protocol After TAVI Implantation
NCT05758909
Fundación EPIC
RecruitingWarfarin Patient Self-management Implementation in the US Healthcare System
NCT04766216
University of UtahN/A
RecruitingLondon Valvular Heart Disease and Reduced Ejection Fraction Detection in a Multi-ethnic Community Using Cardia
NCT05208567
Queen Mary University of London
Not Yet RecruitingTAVIS Registry - Trilogy Heart Valve System for Management of Patients With Aortic Valve Disease
NCT05536310
JenaValve Technology, Inc.
Active Not RecruitingTRISCEND JAPAN Study
NCT05760989
Edwards LifesciencesN/A
Enrolling By InvitationCT-evaluation of Coronary Ostia Height After Surgical Aortic Valve Replacement.
NCT05714293
Fondazione Policlinico Universitario Agostino Gemelli IRCCSN/A
CompletedBedside Cycling Exercises Post Heart Valve Surgeries
NCT05893433
Cairo UniversityN/A
UnknownESP Block in Robotic Cardiac Surgery
NCT05702151
Hospital Clinic of BarcelonaN/A
RecruitingPrognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics
NCT06001073
First Affiliated Hospital Xi'an Jiaotong University
UnknownResearch on Neurological Prognosis of Patients Undergoing Heart Valve Surgery
NCT05539261
Nanjing University of Traditional Chinese Medicine
CompletedEvaluation of Systemic Microcirculation of Patients Undergoing Heart Valve Surgery
NCT05728047
National Institute of Cardiology, Laranjeiras, Brazil
CompletedPMS Promotes the Recovery of Patients After Heart Valve Replacement
NCT05498948
Hepatopancreatobiliary Surgery Institute of Gansu ProvinceN/A
CompletedProlonged Cardiopulmonary Bypass Time as a Predictive Factor for AGI After Heart Valve Replacement
NCT05498935
Hepatopancreatobiliary Surgery Institute of Gansu Province
UnknownThe Effect of Digital Window on Day and Night Perception Status and Sleep Quality in Intensive Care Patients
NCT05486780
Ankara Yildirim Beyazıt UniversityN/A
UnknownEuropean FIH Study - NeoChord Transcatheter Mitral Repair System for Symptomatic Mitral Regurgitation
NCT05425628
NeoChordN/A
RecruitingRetrospective Prospective Multicentric Clinical Follow up of Patients After Being Treated With TricValve®
NCT05114850
P+F Products + Features GmbH
CompletedEffect Of Power Breath Device On Arterial Blood Gases And Diaphragmatic Excursion After Valve Surgery
NCT06012474
Cairo UniversityN/A
UnknownAcapella Versus Incentive Spirometer on Cardiopulmonary Fitness After Heart Valve Surgery.
NCT05522712
Cairo UniversityN/A
CompletedEarly Exercise Training in Patients Following Heart Valve Surgery for Infective Endocarditis.
NCT05703022
University Hospital of North NorwayN/A
UnknownAcute Kidney Injury After Cardiac Surgery
NCT05079724
Assiut University
CompletedPostoperative Pain Relief With Transversus Thoracis Muscle Plane Block After Cardiac Surgery
NCT04916418
Turku University HospitalPhase 4
CompletedSpectroscopic Assessment of Intramyocardial Oxygen Saturation Feasibility During Open-heart Surgery
NCT05479968
Spectrocor
CompletedInterdisciplinary Perioperative Care in Minimally-invasive Heart Valve Surgery
NCT04977362
Universitätsklinikum Hamburg-EppendorfN/A
CompletedDetection of Right Ventricular Dysfunction by Portal Vein Doppler After Cardiac Surgery
NCT04890860
CMC Ambroise ParéN/A
CompletedProspective Evaluation for Hybrid Cardiac Procedures
NCT05143671
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Active Not RecruitingThe Nordic Aortic Valve Intervention Trial 4 (NOTION-4)
NCT06449469
Rigshospitalet, DenmarkN/A
Active Not RecruitingTRISCEND II Pivotal Trial
NCT04482062
Edwards LifesciencesN/A
CompletedAutonomous Robotics for Transcatheter Cardiac Procedures
NCT04787757
Università Vita-Salute San Raffaele
UnknownSATURN Transcatheter Mitral Valve Replacement for Functional Mitral Regurgitation
NCT04464876
InnovHeartN/A
Active Not Recruiting2019-06 TRISCEND Study
NCT04221490
Edwards LifesciencesN/A
RecruitingMulticenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System
NCT04190602
NeoChord
UnknownLoop Gain in the Reversion of OSA Treated by Either CPAP or Cardiac Valve Replacement
NCT03839654
Nanjing Medical UniversityN/A
UnknownRHEIA (Randomized researcH in womEn All Comers With Aortic Stenosis)
NCT04160130
OptimapharmN/A
UnknownCardiovascular Acoustics and an Intelligent Stethoscope
NCT04445012
Papworth Hospital NHS Foundation Trust
CompletedIs Myocardial Revascularization Really Necessary in Patients With ≥50-70% Coronary Stenosis Undergoing Valvula
NCT05836467
Michele De Bonis
WithdrawnRapid Non-invasive Detection of Aortic Stenosis
NCT04024566
Avicena LLC
RecruitingTranspacific TAVR Registry
NCT03826264
Duk-Woo Park, MD
UnknownOnline Videodensitometric Assessment of Aortic Regurgitation in the Cath-Lab
NCT04047082
Imperial College London
TerminatedClinical Outcomes in Patients Treated With SternaLock Blu
NCT03709693
Zimmer Biomet
UnknownErector Spinae Plane Block for Minimal Invasive Cardiac Surgery (Heart-Port).
NCT04011501
Hospital Clinic of BarcelonaN/A
CompletedThe Improving ATTENDance to Cardiac Rehabilitation Trial
NCT03646760
Henry Ford Health SystemN/A
WithdrawnPercutaneous Device Closure for Significant Paravalvular Leakage After Transcatheter or Surgical Valve Replace
NCT03793296
Seung-Jung ParkN/A
UnknownFemorofemoral Bypass in Redo Cardiac Surgery
NCT03624738
Assiut UniversityN/A
CompletedOPTIMA: Psychological Distress and the Effect of Intensive Group Based Cognitive Therapy in Patients With Newl
NCT04254315
University Hospital Bispebjerg and FrederiksbergN/A
UnknownPerioperative Rehabilitation of Cardiac Valvular Surgery
NCT03709511
Guangdong Provincial People's HospitalN/A
CompletedFearon Algorithm in Warfarin Patient Self-Management
NCT03911661
University of UtahN/A
CompletedFeasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification
NCT03539458
Abbott Medical DevicesN/A
TerminatedEarly Feasibility Study of the Percutaneous 4Tech TriCinch Coil Tricuspid Valve Repair System
NCT03632967
4Tech Cardio Ltd.N/A
Active Not RecruitingClinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System
NCT03433274
Abbott Medical DevicesN/A
CompletedFast Track Concept for Transfemoral TAVI
NCT04792827
University Hospital Schleswig-Holstein
RecruitingThe EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
NCT03142152
Cardiac Dimensions, Inc.N/A
CompletedAssessments of Thrombus Formation in TAVI
NCT03248232
Kumamoto University
CompletedMedtronic HAMMOCK Post Approval Study
NCT03139721
Medtronic Cardiac Surgery
UnknownSodium Creatine Phosphate in Heart Valve Surgery
NCT03186053
Chinese Academy of Medical Sciences, Fuwai HospitalN/A
RecruitingThe Study of Biological Prosthetic Heart Valves With the "Easy Change" System
NCT04442100
Tomsk National Research Medical Center of the Russian Academy of SciencesN/A
CompletedIndividualised Follow-up After Valve Surgery
NCT03053778
Odense University HospitalN/A
UnknownJENAVALVE AS EFS TRIAL: Pericardial TAVR Aortic Stenosis Study
NCT02732691
JenaValve Technology, Inc.N/A
CompletedTRI-REPAIR: TrIcuspid Regurgitation RePAIr With CaRdioband Transcatheter System
NCT02981953
Edwards LifesciencesN/A
UnknownChina Senile Valvular Heart Disease Cohort Study
NCT02865798
China National Center for Cardiovascular Diseases
TerminatedREPAIR - transcatheteR rEPair of mitrAl Insufficiency With caRdioband System
NCT02703311
Edwards LifesciencesN/A
Active Not RecruitingComparison of TAVR With SAVR in Younger Low Surgical Risk Patients With Severe Aortic Stenosis
NCT02825134
Ole De BackerN/A
UnknownPerformance of the CARDIOGARD Cannula
NCT02764645
Rambam Health Care CampusN/A
CompletedCytokine Clearance With Cytoabsorbant Device During Cardiac Bypass
NCT02775123
Centre Hospitalier Universitaire VaudoisPhase 1 / Phase 2
CompletedComparison of a Rivaroxaban-based Strategy With an Antiplatelet-based Strategy Following Successful TAVR for t
NCT02833948
ECRI bvPhase 3
UnknownChina Valve Registry Study-1
NCT02623907
Shanghai Zhongshan Hospital
CompletedCardiopulmonary Bypass Prime Solution in Patients Undergoing Heart Valve Surgery
NCT05223361
Rajaie Cardiovascular Medical and Research CenterPhase 3
CompletedQuality of Life After Ministernotomy Versus Full Sternotomy Aortic Valve Replacement
NCT02726087
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y SaludN/A
CompletedPersonalised Decision Support for Heart Valve Disease
NCT04068740
German Heart Institute
UnknownDoes Frailty Help Predict Postoperative Outcomes in Cardiac Surgery?
NCT02749149
King's College Hospital NHS Trust
RecruitingResearch on Optimal Diagnosis and Treatment of Cardiorenal Syndrome
NCT05397392
Nanjing First Hospital, Nanjing Medical University
CompletedStent Geometry in Sutureless Bioprosthetic Valves
NCT03753126
Karolinska University HospitalN/A
CompletedTelomere Biology and AKI in Cardiac Surgery
NCT02692833
Queen Mary University of London
UnknowncoRonary assEssment of Preoperative vaLvulopathy pAtients Using ComputEd Tomographic Angiography (REPLACE)
NCT02632617
Chinese Academy of Medical Sciences, Fuwai Hospital
UnknownCorrelation of Brain and Thenar Muscle Oximetry During Cardiac Surgery With Parameters of Acute Kidney Injury
NCT02979275
Medical University of Gdansk
CompletedNitric Oxide in Cardiopulmonary Bypass for Renal Protection in Cardiac Surgery
NCT03527381
Nikolay KamenshchikovPhase 1 / Phase 2
CompletedThe Bicuspid Aortic Stenosis Following Transcatheter Aortic Valve Replacement Registry
NCT02394184
Seung-Jung Park
TerminatedMitroflow DL Post Approval Study- North America
NCT02351726
LivaNovaN/A
CompletedNormal Values in Stress Echocardiographic Parameters in Patients After Successful Mitral Valve Repair for Orga
NCT02371863
UMC Utrecht
CompletedBIOVALVE - I / II Clincial Investigation
NCT02249000
Biotronik AGN/A
CompletedDexmedetomidine and Outcomes of Cardiac Surgery (DOCS)
NCT02237495
Xijing HospitalPhase 2 / Phase 3
UnknownHigh-sensitivity Troponin T in Acute Myocardial Infarction After Cardiac Valvular Surgery
NCT02518282
University of Valladolid
TerminatedFirst in Man Study of the JenaValve TAVI Plus System Transfemoral
NCT02818959
JenaValve Technology, Inc.N/A
CompletedBleeding in Partial Upper Hemisternotomy Versus Full Sternotomy Aortic Valve Replacement
NCT02272621
Karolinska University HospitalN/A
CompletedCardiac Function After Minimally Invasive Aortic Valve Implantation
NCT01972555
Karolinska University HospitalN/A
CompletedRemoval of Cytokines During Extracorporeal Circulation in Cardiac Surgery
NCT02297334
Universitätsklinikum Hamburg-EppendorfN/A
CompletedPrevention of Renal Failure by Nitric Oxide in Prolonged Cardiopulmonary Bypass.
NCT01802619
Xijing HospitalPhase 1 / Phase 2
CompletedNeoChord TACT Post-Market Surveillance Registry
NCT01784055
NeoChord
CompletedAtrovastatin for Preventing Atrial Fibrillation Following Open Cardiac Valve Repair
NCT02084069
Urmia University of Medical SciencesPhase 3
CompletedSONOlysis in Risk REduction of Symptomatic and Silent Brain infarCtions dUring Cardiac surgEry
NCT01591018
University Hospital OstravaPhase 3
UnknownA Trial of Genotype-based Warfarin Initiation in Patients With Mechanical Prosthetic Heart Valve
NCT01633957
Xi ZhangN/A
CompletedPost-Approval Study Protocol of the St. Jude Medical Trifecta Valve
NCT01514162
Abbott Medical DevicesN/A
UnknownUse of Standardized Diagnostic Imaging Data for Image Fusion in the Hybrid Operating Room
NCT01821651
University of ZurichN/A
TerminatedDabigatran Etexilate in Patients With Mechanical Heart Valves
NCT01452347
Boehringer IngelheimPhase 2
CompletedDoes Coronary Angiography Cause Cognitive Dysfunction?
NCT01428947
Karolinska Institutet
CompletedCorticosteroid Prophylaxis on the Cardiopulmonary Bypass-Induced Systemic Inflammatory Response
NCT01296074
Beijing Anzhen HospitalN/A
CompletedCentrifugation vs. Multiple-pass Hemofiltration of the Residual Cardiopulmonary Bypass Volume
NCT01416792
University of SaskatchewanN/A
CompletedEchocardiography as Risk-Assessment for Major Adverse Cardiac Events in Major Vascular Surgery Patients
NCT04836702
University of Virginia
Active Not RecruitingHealth Data Warehouse on Aortic Insufficiency
NCT06420895
Lille Catholic University
UnknownAcupuncture Improves Sleep in Patients Undergoing Cardiopulmonary Bypass
NCT01231776
Xijing HospitalN/A
WithdrawnPost Market ATS 3f® Aortic Bioprosthesis, Model 1000, Size 19mm
NCT01156272
Medtronic Cardiovascular
CompletedEffect of Combined Remote Ischemic Preconditioning and Postconditioning on Acute Pulmonary Injury in Patients
NCT01427621
Yonsei UniversityPhase 4
CompletedNormothermiс Cardiopulmonary Bypass Increases Cerebral Oxygenation During Valve Surgery
NCT01685554
Northern State Medical UniversityN/A
CompletedDepth of Anesthesia in Cardiac Surgery
NCT01524354
Northern State Medical UniversityN/A
CompletedA Post-Marketing Study for On Label Evaluation of the GE Vscan Ultrasound Imaging System
NCT01076296
GE Healthcare
TerminatedATS 3f(r) Aortic Bioprosthesis Model 1000 Post Approval Study
NCT01116037
Medtronic CardiovascularN/A
CompletedAutomated Fastener Device Versus Manually Tied Knot in MiAVR
NCT03664102
Centre Hospitalier La Chartreuse
CompletedClinical Investigation of the Freedom SOLO Stentless Heart Valve
NCT00876525
Corcym S.r.lN/A
CompletedAnesthetic Management and Remote Reperfusion Injuries
NCT00745810
National Taiwan University Hospital
CompletedPreoperatively Orientation in Cardiac Surgery: Nurses Intervention on Patients Recovery
NCT01559610
Instituto de Cardiologia do Rio Grande do SulN/A
RecruitingThe Prospective LEUVEN Transcatheter Valve Therapy Registry
NCT03674788
Universitaire Ziekenhuizen KU Leuven
CompletedPGx Study to Develop and Validate the Predictive Warfarin Dosing Algorithm for Personalized Warfarin Pharmacot
NCT01178502
Inje University
CompletedHeart Valve Prosthesis-Patient Mismatch
NCT00629902
Florence Nightingale Hospital, Istanbul
CompletedMachine Learning-Based Risk Profile Classification of Patients Undergoing Elective Heart Valve Surgery
NCT03724123
Kepler University Hospital
CompletedEffect of Remote Ischemia Preconditioning on Myocardial Injury in Patients Undergoing Heart Valve Surgery
NCT01175681
Sun Yat-sen UniversityN/A
CompletedMelody Transcatheter Pulmonary Valve (TPV) Post-Market Surveillance Study
NCT00688571
Medtronic Cardiac Rhythm and Heart FailureN/A
CompletedHemodynamic Performance in Stentless Heart Valves
NCT00377871
University of AarhusN/A
CompletedMethods Study to Evaluate Use of Cardiac Ultrasound to Assess Heart Valve Abnormality in People.
NCT00359489
Pfizer
CompletedProlongation of the Interval Between Monitoring of Warfarin in Stable Patients
NCT00356759
Hamilton Health Sciences CorporationPhase 2
UnknownChronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study)
NCT00418041
Hiroaki Shimokawa, MD, PhD
CompletedOntario Multidetector Computed Tomographic (MDCT) Coronary Angiography Study (OMCAS)
NCT00371891
St. Joseph's Healthcare HamiltonPhase 4
CompletedATS 3f Enable(tm) Aortic Bioprosthesis, Model 6000
NCT01116024
Medtronic CardiovascularN/A
CompletedPatients Perception of Mechanical Heart Valve Sounds: Psychoacoustics and Quality of Life
NCT00362401
University of Aarhus
Unknown"Salvage Use" of Recombinant Factor VIIa After Inadequate Haemostasis in Complex Cardiac Surgery
NCT00214656
Austin HealthPhase 3
TerminatedCTI-01 (Ethyl Pyruvate) Safety and Complication Prevention in Cardiac Surgery Patients on Cardiopulmonary Bypa
NCT00107666
Critical TherapeuticsPhase 2
CompletedPergolide Treatment and Valvular Heart Disease
NCT00234364
Århus Amt
UnknownMulticenter Study on Fibrotic Valvular Heart Disease in Patients With Parkinson's Disease Treated With Dopamin
NCT00196898
German Parkinson Study Group (GPS)
CompletedA Randomized Clinical Trial of Metoprolol in Participants With Mitral Regurgitation.
NCT00166400
Mayo ClinicPhase 4
CompletedClinical Investigation Of The Mitroflow Aortic Pericardial Heart Valve
NCT00630916
Sorin Group USA, Inc.N/A
CompletedGlucose Control in Open Heart Surgery
NCT00370643
University of Sao PauloPhase 1
TerminatedConventional Versus Mini-Sternotomy for Aortic Valve Surgery
NCT00221663
University Hospital, BordeauxPhase 2 / Phase 3
TerminatedATS 3f(r) Aortic Bioprosthesis Model 1000, 19mm
NCT00657826
Medtronic CardiovascularN/A
UnknownCardiac Operation Under Totally Endoscope and Cardiopulmonary Bypass (CPB)
NCT00921596
Xijing HospitalPhase 1 / Phase 2
CompletedThe Short Form-36: Pre- Versus Post-Surgical Administration in Cardiac Surgery Patients
NCT00226265
Weill Medical College of Cornell University