Trials / Sponsors / Edwards Lifesciences
Edwards Lifesciences
Industry · 126 registered clinical trials — 16 currently recruiting.
| Status | Trial | Phase | Started |
|---|---|---|---|
| Suspended | INSPIRIS RESILIA Aortic Valve, Valve-in-Valve Surveillance Study Aortic Valve Replacement | — | 2028-06-01 |
| Not Yet Recruiting | ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral Mitral Regurgitation, Mitral Valve Disease, Mitral Stenosis | N/A | 2027-01-01 |
| Not Yet Recruiting | The Continuity Study Blood Pressure | N/A | 2025-11-01 |
| Completed | ClearSight NextGen1 Study Blood Pressure | N/A | 2025-10-16 |
| Recruiting | HemoSphere Alta Study Hemodynamic Instability | — | 2025-10-14 |
| Recruiting | Real World Data Collection on the INSPIRIS RESILIA Aortic Valve Aortic Valve Disease | — | 2025-07-30 |
| Recruiting | MITRIS China Post Market Clinical Follow-up (PMCF) Study Mitral Valve Replacement | — | 2025-07-08 |
| Recruiting | TTVR STRONG Under Coverage With Evidence Development (CED) Study Tricuspid Regurgitation | — | 2025-03-19 |
| Recruiting | Real World European Investigation of Safety and Clinical Efficacy of the EVOQUE System (TRISCEND III EU) Tricuspid Valve Regurgitation, Heart Valve Diseases, Cardiovascular Diseases | — | 2024-10-01 |
| Recruiting | Personal BP - CAI Study Blood Pressure | N/A | 2024-06-03 |
| Completed | ClearSight Baby Cuff Blood Pressure | — | 2024-01-10 |
| Recruiting | ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosth Aortic Valve Insufficiency, Aortic Valve Stenosis | N/A | 2023-11-22 |
| Completed | SMART TRENDS Study Moderate to High-risk Noncardiac Surgery | N/A | 2023-07-11 |
| Active Not Recruiting | ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System Heart Failure | N/A | 2023-04-01 |
| Active Not Recruiting | TRISCEND JAPAN Study Tricuspid Valve Regurgitation, Heart Valve Diseases, Cardiovascular Diseases | N/A | 2023-02-06 |
| Active Not Recruiting | TVMR With the Innovalve System Trial - Pilot Study in Italy Mitral Valve Regurgitation (Degenerative or Functional) | N/A | 2023-01-24 |
| Active Not Recruiting | Real-world Clinical Outcomes of the MITRIS RESILIA Mitral Valve Mitral Stenosis, Mitral Valve Insufficiency | — | 2023-01-11 |
| Recruiting | TVMR With the INNOVALVE System Trial - Early Feasibility Study Mitral Valve Regurgitation (Degenerative or Functional) | N/A | 2022-09-01 |
| Active Not Recruiting | INSPIRIS China PMCF Study Aortic Valve Replacement | — | 2022-07-13 |
| Active Not Recruiting | ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve Aortic Stenosis, Severe | N/A | 2022-06-20 |
| Active Not Recruiting | ALTERRA Post-Approval Study Pulmonary Valve Insufficiency, Complex Congenital Heart Defect, Tetralogy of Fallot | — | 2022-05-12 |
| Active Not Recruiting | HPI (Hypotension Prediction Index) Care Trial Cardiopulmonary Bypass Surgery | N/A | 2022-03-28 |
| Active Not Recruiting | China S3 PMS: SAPIEN 3 China Post Market Registry Study Aortic Stenosis, Severe | — | 2022-01-24 |
| Completed | TVMR With the Innovalve System Trial - Pilot in Georgia Mitral Valve Regurgitation (Degenerative or Functional) | N/A | 2021-12-01 |
| Terminated | Hypotension Prediction Index (HPI) SMART-BP Trial Moderate to High-risk Noncardiac Surgery | N/A | 2021-11-17 |
| Recruiting | PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR Aortic Stenosis, Calcific, Aortic Valve Stenosis | N/A | 2021-10-12 |
| Completed | TVMR With the Innovalve System Trial - First In Human Israel Mitral Valve Regurgitation (Degenerative or Functional) | N/A | 2021-10-01 |
| Completed | The EU Hyprotect Registry Hemodynamic Monitoring | — | 2021-09-28 |
| Completed | HUDDLE: Heart Health: Understanding & Diagnosing Disease by Leveraging Echocardiograms Cardiovascular Diseases, Heart Diseases | — | 2021-07-14 |
| Completed | SAPIEN 3 Ultra EU PMS Aortic Stenosis, Aortic Valve Stenosis | — | 2021-04-20 |
| Active Not Recruiting | COMPASSION S3 Post-Approval Study Complex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Insufficiency | — | 2021-04-13 |
| Active Not Recruiting | TRISCEND II Pivotal Trial Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease | N/A | 2021-04-09 |
| Withdrawn | ExplorATory Study oF the EdWards Transcatheter Atrial Shunt System (AlT FloW Germany) Heart Failure | N/A | 2021-02-22 |
| Active Not Recruiting | Transcatheter Repair of Tricuspid Regurgitation With Edwards PASCAL Transcatheter Valve Repair System Tricuspid Valve Insufficiency | — | 2021-01-15 |
| Active Not Recruiting | Beating Heart Mitral Valve Repair With the HARPOON™ System Mitral Regurgitation | N/A | 2020-12-16 |
| Recruiting | The ENCIRCLE Trial Mitral Regurgitation, Mitral Valve Insufficiency | N/A | 2020-11-12 |
| Terminated | Treatment of Mitral Regurgitation Using a Minimally Invasive Approach With the HARPOON Device. Mitral Regurgitation | N/A | 2020-10-02 |
| Terminated | Observational Registry on the HARPOON Device Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse | N/A | 2020-10-02 |
| Completed | Pediatric Cardiac Output Monitoring Observational Study Pediatric ALL | — | 2020-09-02 |
| Active Not Recruiting | SAPIEN 3 Ultra System PMCF Aortic Valve Stenosis | — | 2020-06-30 |
| Active Not Recruiting | 2019-06 TRISCEND Study Tricuspid Valve Regurgitation, Heart Valve Diseases, Cardiovascular Diseases | N/A | 2020-05-06 |
| Recruiting | Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease | N/A | 2019-12-11 |
| Recruiting | MiCLASP Post Market Clinical Follow-Up (PMCF) Study Mitral Regurgitation, Mitral Insufficiency | — | 2019-08-23 |
| Active Not Recruiting | Transcatheter Repair of Tricuspid Regurgitation With Edwards Cardioband TR System Post Market Study (TriBAND) Tricuspid Regurgitation, Tricuspid Insufficiency | — | 2019-07-24 |
| Active Not Recruiting | Exploratory Study of the Edwards APTURE Transcatheter Shunt System (ALT-FLOW Canada) Heart Failure | N/A | 2019-07-10 |
| Completed | Edwards PASCAL Transcatheter Valve Repair System Registry Mitral Valve Insufficiency | — | 2019-05-27 |
| Completed | Hypotension Prediction Index Study (HPI Study) Hypotension | — | 2019-05-16 |
| Completed | Edwards CLASP TR EFS Tricuspid Regurgitation | N/A | 2019-02-05 |
| Completed | CENTERA PMCF: Post-Market Follow-up of the CENTERA Transcatheter Heart Valve System Aortic Valve Stenosis | — | 2019-01-07 |
| Completed | ClearSight System CHN Study Patient With Clinically Indicated Invasive Monitoring | — | 2018-12-25 |
| Active Not Recruiting | Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency | N/A | 2018-11-30 |
| Terminated | RESILIENCE Trial: Evaluation of the Durability of Aortic Bioprostheses/Valves With RESILIA Tissue in Subjects Aortic Valve Replacement | — | 2018-11-05 |
| Active Not Recruiting | ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenos Aortic Valve Stenosis | N/A | 2018-09-18 |
| Active Not Recruiting | Early Feasibility Study - Edwards APTURE Transcatheter Shunt System Heart Failure | N/A | 2018-07-31 |
| Active Not Recruiting | Clinical Study of Edwards Cardioband FIT Valve Repair System Tricuspid Regurgitation | N/A | 2018-07-01 |
| Unknown | Edwards Cardioband European Post-Market Study, MiBAND Mitral Regurgitation, Mitral Insufficiency, Mitral Repair | — | 2018-06-06 |
| Completed | The SAPIEN 3 Ultra System in Intermediate Risk Patients With Symptomatic, Severe Aortic Stenosis Aortic Valve Stenosis | N/A | 2018-06-01 |
| Completed | China S3: Safety and Effectiveness of Edwards Lifesciences SAPIEN 3 THV in the Chinese Population Aortic Stenosis, Symptomatic Aortic Stenosis, Aortic Regurgitation | N/A | 2018-05-23 |
| Completed | Assisted Fluid Management IDE Study Non-Cardiac/ Non-Thoracic Surgery, Abdominal Surgery, Pelvic Surgery | N/A | 2018-04-19 |
| Active Not Recruiting | PARTNER 3 Trial - Mitral Valve in Valve Mitral Valve Insufficiency, Mitral Valve Disease, Mitral Valve Regurgitation | N/A | 2018-02-01 |
| Completed | China XT: Safety and Effectiveness of Edwards Lifesciences SAPIEN XT THV in the Chinese Population Aortic Stenosis, Symptomatic Aortic Stenosis, Aortic Regurgitation | N/A | 2017-09-18 |
| Active Not Recruiting | SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitati Mitral Regurgitation, Mitral Disease | N/A | 2017-09-14 |
| Active Not Recruiting | ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent Pulmonary Disease, Transcatheter Pulmonary Valve Replacement (TPVR), Tetralogy of Fallot | N/A | 2017-08-22 |
| Completed | COMPASSION XT PAS - Post-approval Study of the SAPIEN XT THV in Patients With Pulmonary Valve Dysfunction Pulmonary Valve Insufficiency, Pulmonary Valve Stenosis, Heart Defects, Congenital | — | 2017-07-17 |
| Active Not Recruiting | EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis Heart Diseases, Aortic Stenosis, Severe | N/A | 2017-07-12 |
| Unknown | CLEAR Sepsis Clinical Study Sepsis | — | 2017-06-29 |
| Completed | The CLASP Study Edwards PASCAL TrAnScatheter Mitral Valve RePair System Study Mitral Valve Regurgitation | N/A | 2017-06-27 |
| Terminated | Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE) Functional Mitral Regurgitation, Mitral Regurgitation, Mitral Insufficiency | N/A | 2017-06-01 |
| Terminated | Safety and Performance Study of the Harpoon Mitral Valve Repair System Mitral Valve Regurgitation, Mitral Valve Prolapse, Mitral Valve Insufficiency | N/A | 2017-05-16 |
| Recruiting | PARTNER 3 Trial - Aortic Valve-in-Valve Aortic Stenosis, Aortic Stenosis, Severe | N/A | 2017-01-05 |
| Withdrawn | CardiAQ-Edwards™ Transcatheter Mitral Valve Replacement (TMVR) Study Mitral Valve Regurgitation | Phase 1 / Phase 2 | 2016-11-01 |
| Completed | TRI-REPAIR: TrIcuspid Regurgitation RePAIr With CaRdioband Transcatheter System Tricuspid Valve Insufficiency, Tricuspid Regurgitation, Tricuspid Valve Regurgitation | N/A | 2016-10-01 |
| Completed | The SPACER Trial - Repair of Tricuspid Valve Regurgitation Using the Edwards TricuSPid TrAnsCatheter REpaiR Sy Tricuspid Valve Regurgitation | N/A | 2016-09-14 |
| Active Not Recruiting | A Clinical Trial of Transcatheter Aortic Valves in Dialysis Patients (Japan) Aortic Stenosis | N/A | 2016-09-01 |
| Terminated | REPAIR - transcatheteR rEPair of mitrAl Insufficiency With caRdioband System Mitral Valve Insufficiency, Cardiac Valve Annuloplasty, Mitral Valve Annuloplasty | N/A | 2016-08-01 |
| Recruiting | COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunct Complex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Insufficiency | N/A | 2016-07-05 |
| Completed | CE Mark Study for the Harpoon Medical Device Mitral Valve Regurgitation, Mitral Valve Prolapse, Mitral Valve Insufficiency | N/A | 2016-04-28 |
| Active Not Recruiting | PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis | N/A | 2016-03-01 |
| Completed | EDWARDS INTUITY Elite Valve System Aortic Valve Disease, Aortic Stenosis | — | 2016-02-01 |
| Completed | CE Mark Study for the Harpoon Medical Device in Poland Mitral Valve Regurgitation, Mitral Valve Prolapse, Mitral Valve Insufficiency | N/A | 2015-12-11 |
| Completed | COMMENCE Pulmonary: Clinical Evaluation of Edwards Pericardial Aortic Bioprosthesis (Model 11000A) for Pulmona Pulmonary Valve Insufficiency, Pulmonary Valve Degeneration, Congenital Pulmonary Valve Abnormality | N/A | 2015-12-01 |
| Completed | Early Feasibility Study of the Edwards FORMA Tricuspid Transcatheter Repair System Tricuspid Valve Regurgitation | N/A | 2015-12-01 |
| Withdrawn | Early Feasibility Study of the CardiAQ™ TMVI System (Transfemoral and Transapical DS) Mitral Insufficiency, Heart Valve Disease, Cardiovascular Disease | N/A | 2015-08-01 |
| Terminated | A Clinical Study of the CardiAQ™ TMVI System (Transapical DS) Mitral Insufficiency, Heart Valve Disease, Cardiovascular Disease | N/A | 2015-06-01 |
| Completed | CENTERA-2: Safety and Performance Study of the Edwards CENTERA-EU Self-Expanding Transcatheter Heart Valve Aortic Valve Disease | N/A | 2015-03-01 |
| Completed | Safety and Early Feasibility Study of the Harpoon Medical Device (EFS) Mitral Valve Regurgitation, Mitral Valve Prolapse, Mitral Valve Insufficiency | N/A | 2015-02-15 |
| Active Not Recruiting | Edwards EVOQUE Eos MISCEND Study Mitral Valve Regurgitation (Degenerative or Functional) | N/A | 2015-02-06 |
| Completed | PARTNER II Trial: S3iCAP Aortic Stenosis | N/A | 2015-01-01 |
| Withdrawn | GlucoClear ICU Study Intensive Care Unit Blood Glucose Monitoring | — | 2014-12-01 |
| Terminated | Clinical Study to Evaluate the Performance of Magna Ease Heart Valve in Chinese Patients Mitral Valve or Aortic Valve Replacement | — | 2014-11-10 |
| Completed | Clinical Study to Evaluate the Performance of Perimount Heart Valve in Chinese Patients Mitral Valve or Aortic Valve Replacement | — | 2014-09-25 |
| Completed | SOURCE 3: Observational Study to Evaluate Safety and Performance of SAPIEN 3 THV System in Real Life Practice Aortic Stenosis | — | 2014-07-01 |
| Completed | PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - S3 Intermediate Symptomatic Severe Aortic Stenosis | N/A | 2014-02-17 |
| Completed | PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - High Risk and Nested Registry 7 Symptomatic Severe Aortic Stenosis | N/A | 2013-10-01 |
| Completed | GlucoClearTM System ICU Study Accurate Blood Glucose Monitoring in Critical Care Setting | — | 2013-04-01 |
| Completed | Safety and Performance Study of the Edwards CENTERA Self-Expanding Transcatheter Heart Valve Aortic Valve Disease | N/A | 2013-02-01 |
| Completed | Safety and Performance Study of the Edwards SAPIEN 3 Transcatheter Heart Valve/ The SAPIEN 3 Study Aortic Valve Disease | N/A | 2013-01-01 |
| Active Not Recruiting | ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New T Aortic Stenosis, Mitral Stenosis, Aortic Valve Insufficiency | N/A | 2012-12-11 |
| Completed | EDWARDS INTUITY Valve System CADENCE Study Aortic Valve Disease, Aortic Stenosis | N/A | 2012-10-01 |
| Completed | Surgical Treatment of Aortic Stenosis With a Next Generation, Rapid Deployment Surgical Aortic Valve Aortic Valve Stenosis, Aortic Valve Stenosis With Insufficiency, Regurgitation, Aortic Valve | N/A | 2012-09-26 |
| Completed | EDWARDS INTUITY Valve System FOUNDATION Study Aortic Valve Disease, Aortic Stenosis, Rapid Deployment Valves | — | 2012-07-01 |
| Completed | PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - Nested Registry 3/Valve-in-Valve Aortic Stenosis, Cardiomyopathy, Hypertrophic | N/A | 2012-06-11 |
| Completed | EDWARDS INTUITY Valve System CADENCE-MIS Study Aortic Valve Disease, Aortic Stenosis | N/A | 2012-05-01 |
| Completed | MITRAFIT- Cardinal Adjustable Mitral Repair Follow-up International Postmarketing Surveillance (PMS) Mitral Regurgitation | — | 2012-05-01 |
| Completed | The SOLACE-AU Clinical Trial Severe, Symptomatic Aortic Stenosis | N/A | 2012-04-01 |
| Completed | Cardioband With Transfemoral Delivery System Mitral Regurgitation | N/A | 2011-09-01 |
| Completed | Clinical Trial of the Edwards Aortic Bioprosthesis, Model 11000 Aortic Valve Disorder, Aortic Valve Insufficiency, Aortic Valve Stenosis | N/A | 2011-07-01 |
| Completed | PREVAIL-20J - Transfemoral Placement of 20mm Aortic Balloon Expandable Transcatheter Valve Trial Aortic Valve Stenosis | N/A | 2011-06-01 |
| Completed | The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves - PII B Severe, Symptomatic, Calcific Aortic Stenosis | N/A | 2011-03-09 |
| Completed | Magna Mitral - 23mm Mitral Heart Valve Disease | N/A | 2011-03-01 |
| Completed | PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - XT Intermediate and High Risk Symptomatic Severe Aortic Stenosis | N/A | 2011-03-01 |
| Completed | Pulmonic Valve REplacement Multi-discIpline EMEA Registry Pulmonary Regurgitation, Pulmonary Insufficiency, Pulmonary Stenosis | — | 2011-01-01 |
| Terminated | V-Chordal Adjustable System for Chordal Replacement in Mitral Valve Insufficiency Due to Leaflet Prolapse Mitral Leaflet Prolapse | Phase 2 | 2010-11-01 |
| Completed | SOURCE XT REGISTRY Severe Aortic Stenosis | — | 2010-09-01 |
| Completed | PREVAIL-J - Transfemoral & Transapical Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Japa Aortic Valve Stenosis | N/A | 2010-04-01 |
| Completed | CARDINAL Adjustable Annuloplasty Ring System For Treatment of Mitral Regurgitation Mitral Valve Insufficiency | N/A | 2010-03-01 |
| Completed | Clinical Evaluation of a New Transpulmonary Thermodilution Method to Assess Thermodilution Cardiac Output, Glo Cardiac Output and Preload Assessment, Lung Water Assessment | — | 2010-01-01 |
| Completed | Surgical Treatment of Aortic Stenosis With a Next Generation Surgical Aortic Valve Aortic Valve Stenosis With Insufficiency, Aortic Valve Stenosis | N/A | 2010-01-01 |
| Completed | PREVAIL-TA: Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Europe) Aortic Valve Stenosis | N/A | 2009-09-01 |
| Completed | Clinical Study of the Intravenous Blood Glucose System in Hospitalized Adult Elective or Non-Emergent Surgery Blood Glucose | — | 2009-06-01 |
| Completed | PREVAIL-TF: Transfemoral Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Europe) Aortic Valve Stenosis | N/A | 2008-12-01 |
| Completed | COMPASSION - COngenital Multicenter Trial of Pulmonic VAlve Regurgitation Studying the SAPIEN InterventIONal T Pulmonary Valve Insufficiency, Pulmonary Regurgitation, Dysfunctional RVOT Conduit | N/A | 2008-04-08 |
| Completed | Carpentier-Edwards PERIMOUNT Magna Ease Pericardial Bioprosthesis, Model 3300TFX Coronary Artery Disease, Aortic Valve Disorder, Heart Failure | N/A | 2007-10-01 |
| Completed | Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol Coronary Artery Disease, Mitral Valve Regurgitation, Mitral Valve Incompetence | N/A | 2007-08-01 |
| Completed | THE PARTNER TRIAL: Placement of AoRTic TraNscathetER Valve Trial Critical Aortic Stenosis | N/A | 2007-04-01 |
| Completed | Using Minimally Invasive Cardiac Output Data vs. Standard Care for Patients Emergently Admitted to the Intensi Cardiac Output, High, Cardiac Output, Low | — | 2006-07-01 |