NCT01428947

Does Coronary Angiography Cause Cognitive Dysfunction?

Study of Cognitive Function Before and After Coronary Angiography

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 80 (actual)
• Sponsor: Karolinska Institutet · Academic / Other
• Sex: All
• Age: 35 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to study if coronary angiography cause cognitive dysfunction.

Detailed description

We have previously shown, using transcranial doppler, that coronary angiography cause cerebral microembolism. Cerebral microemboli were more common using the radial than femoral approach. Previously, cerebral microembolism has been associated with new cerebral lesions on MRI. The clinical significance of these new lesions is not determined. The primary aim of this pilot study is to see if coronary angiography cause cognitive dysfunction determined by the MoCA-test. A secondary aim is to relate cognitive dysfunction to cerebral microembolism measured by transcranial doppler. A third aim is to study potential differences between the femoral and radial approaches.

Conditions

• Coronary Heart Disease
• Heart Valve Diseases

Interventions

Type	Name	Description
PROCEDURE	Arterial approach	Randomization to right radial or femoral approach

Timeline

• Start date: 2011-09-01
• Primary completion: 2012-06-01
• Completion: 2012-06-01
• First posted: 2011-09-05
• Last updated: 2016-02-24

Locations

1 site across 1 country: Sweden