NCT06420895

Health Data Warehouse on Aortic Insufficiency

Setting up a Health Data Warehouse on Aortic Insufficiency

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Lille Catholic University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This project aims to create a data warehouse based on care data of patients with an aortic insufficiency admitted to the Groupement des Hôpitaux de l'Institut Catholique de Lille (GHICL) since 2011. The aim is to enable the utilisation of this data for research purposes.

Detailed description

All eligible patients will be informed about the collection of their data during their care at the Valvulopathies Center of Groupement des Hopitaux de l'Institut Catholique de Lille (GHICL). Their consent will be needed for the inclusion. Data will be collected exclusively by the person responsible for implementing the data processing and his/her authorised staff. For all patients, data will be collected retrospectively, based on medical records (electronic or paper), and information available on the various care software linked to the patient's file. There will not be changes in the the patient's care. At the GHICL Valvulopathy Centre, in accordance with European recommendations, patients with aortic insufficiency are monitored as follows, depending on the severity of the pathology: * Minimal aortic insufficiency: follow-up every 3-5 years (approximately) including clinical examination and transthoracic echocardiogram (TTE) * Moderate/medium aortic insufficiency: follow-up every 1-2 years with clinical examination, laboratory tests and TTE. * Significant aortic insufficiency: follow-up every 6-12 months including a clinical examination, a biological assessment and a c+/- TTE coupled with an exercise test. * Cardiac Magnetic Resonance Imaging (MRI) indicated as a second-line procedure after TTE in cases of moderate/medium aortic insufficiency with arguments or doubts about an underestimation of the severity of the aortic insufficiency on TTE, aortic insufficiency of undetermined quantification on TTE, or significant aortic insufficiency on TTE to confirm the severity using a multiparametric approach. * TEE (transesophageal echocardiogram) is indicated as 2nd line after TTE in cases of significant aortic insufficiency as part of the preoperative work-up or moderate/undetermined aortic insufficiency on TTE. The choice between cardiac MRI or TEE, or both, as second-line treatment after TEE, is left to the clinician in current practice, in accordance with the recommendations.

Conditions

• Aortic Insufficiency
• Heart Valve Diseases

Interventions

Type	Name	Description
OTHER	Clinical follow-up	Clinical follow-up of patients
OTHER	Transthoracic Echocardiogram (TTE)	Transthoracic Echocardiogram
OTHER	Magnetic resonance imaging (MRI)	Magnetic resonance imaging
OTHER	Transesophageal echocardiogram (TEE)	Transesophageal echocardiogram

Timeline

• Start date: 2011-01-01
• Primary completion: 2028-12-31
• Completion: 2033-12-31
• First posted: 2024-05-20
• Last updated: 2024-05-20