| Not Yet Recruiting | Early Temporal Dynamics of Optic Nerve Sheath Diameter After Therapy in GCA NCT07508514 | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | — |
| Recruiting | Giant Cell Arteritis - Ways to Precision Medicine NCT07084480 | Wuerzburg University Hospital | — |
| Recruiting | Association of Ultrasonographic Temporal Artery Lesions and Relapse in Patients With Giant Cell Arteritis NCT06894602 | University Hospital, Brest | — |
| Recruiting | Optic Nerve Sheath Ultrasound in Giant Cell Arteritis NCT05749094 | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | — |
| Active Not Recruiting | The Applanation Tonometry in GCA Pilot NCT05703763 | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | — |
| Recruiting | A Clinical Trial to Investigate 18F-AzaFol in the Diagnosis of Large Vessel Vasculitis NCT06335888 | Insel Gruppe AG, University Hospital Bern | Phase 2 |
| Recruiting | Visual Involvement in Giant Cell Arteritis NCT06500728 | ASST Fatebenefratelli Sacco | — |
| Active Not Recruiting | TocilizuMab discontinuAtion in GIant Cell Arteritis NCT06037460 | Centre Hospitalier Universitaire Dijon | Phase 3 |
| Completed | Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Intravenous Secukinumab in Patients With GC NCT06130540 | Novartis Pharmaceuticals | Phase 1 |
| Not Yet Recruiting | Clonal Hematopoiesis in Giant Cell Arteritis NCT06244069 | ASST Fatebenefratelli Sacco | — |
| Recruiting | Investigation of the Influence of the Human Microbiome on Giant Cell Arteritis NCT06279065 | University of Bonn | — |
| Recruiting | Impact of the Spatial Resolution of Several Contrast-enhanced 3D T1-WI Sequences When Diagnosing Giant Cell Ar NCT05854927 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Recruiting | Post-therapeutic Imaging Evaluation of Patients With Horton's Disease (Giant Cell Arteritis) (EvHortim) NCT06004154 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Recruiting | DANIsh VASculitis Database (DANIVAS) NCT05935709 | Aarhus University Hospital | — |
| Recruiting | Assessing Biomarker in Giant Cell Arteritis and Polymyalgia Rheumatic NCT06460142 | University of Bonn | — |
| Recruiting | Risk of Diabetes Mellitus in Patients With Giant Cell Arthritis and Polymyalgia Rheumatica. NCT06011512 | Salome Kristensen | — |
| Recruiting | Armenian NAtionwide REGistry of Systemic Autoimmune and Autoinflammatory Diseases NCT05904301 | Santé Arménie French-Armenian Research Center | — |
| Completed | Histopathological Analysis of Temporal Artery Biopsy Following Dynamic Full-field Optical Coherence Tomography NCT05663333 | Centre Hospitalier William Morey - Chalon sur Saône | — |
| Active Not Recruiting | Methotrexate as Remission Maintenance Therapy After Remission-Induction With Tocilizumab and Glucocorticoids i NCT05623592 | University of Bonn | Phase 2 |
| Completed | Efficacy and Safety of Secukinumab in Patients With New Onset of Giant Cell Arteritis Who Are in Clinical Remi NCT05380453 | Novartis Pharmaceuticals | Phase 3 |
| Completed | FDG Digital PET/CT as First Line Investigation for Giant Cell Arteritis NCT05000138 | Jewish General Hospital | — |
| Recruiting | Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency NCT05435781 | Marianne Christina Klose | Phase 4 |
| Active Not Recruiting | Efficacy of Tocilizumab in Association to Steroids in Giant Cell Arteritis With Cerebro-vascular Involvement NCT04888221 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Terminated | Biologics in Refractory Vasculitis: A Trial of Biologic Therapy for Refractory Primary Non-ANCA Associated Vas NCT05168475 | Cambridge University Hospitals NHS Foundation Trust | Phase 2 |
| Unknown | Pharmacogenetic Studies on Anti-IL-6 Receptor Monoclonal Antibodies on the Treatment of Rheumatic Diseases NCT05045001 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | — |
| Completed | Comparative Study of 3 Tocilizumab Products in Normal Healthy Volunteeers NCT04885829 | Syneos Health | Phase 1 |
| Recruiting | Abatacept for the Treatment of Giant Cell Arteritis NCT04474847 | University of Pennsylvania | Phase 3 |
| Completed | Giant Cell Arteritis - Optimization of Diagnostics NCT05248906 | Rigshospitalet, Denmark | — |
| Recruiting | PRediction of DIverse Glucocorticoids ToxIcity OUtcomeS NCT04664465 | University Hospital, Brest | — |
| Terminated | A Study to Evaluate Guselkumab for the Treatment of Participants With New-onset or Relapsing Giant Cell Arteri NCT04633447 | Janssen Research & Development, LLC | Phase 2 |
| Not Yet Recruiting | Giant Cell Arteritis: Comparison Between Two Standardized Corticosteroids Tapering NCT04012905 | University Hospital, Caen | Phase 3 |
| Active Not Recruiting | Improved Diagnostics and Monitoring of Polymyalgia Rheumatica NCT04519580 | Kresten Krarup Keller | — |
| Unknown | Efficacy of Tocilizumab for the Treatment of Acute AION Related to GCA NCT04239196 | Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts | Phase 2 |
| Recruiting | Rheumatology Patient Registry and Biorepository NCT04402086 | Yale University | — |
| Completed | Giant Cell Arteritis and Differential Diagnoses Associated With Positive Temporal Artery Biopsy NCT04554290 | Central Hospital, Nancy, France | — |
| Recruiting | Vascular MRI Evaluation in Giant Cell Arteritis (VEGA) NCT05865054 | University of Pennsylvania | — |
| Unknown | Prevalence and Seroconversion of COVID-19 in Autoimmune Diseases in Europe NCT04397237 | Pitié-Salpêtrière Hospital | — |
| Completed | Longitudinal Imaging in Patients With Large Vessel Vasculitis to Predict Further Disease Course NCT04204876 | University Hospital, Basel, Switzerland | — |
| Terminated | COVID-19 Infection in Vulnerable Patients With Inflammatory Rheumatic Diseases NCT04335747 | Salome Kristensen | — |
| Completed | Collection and Analysis of the Clinical and Biological Characteristics of Patients Treated for Giant Cells ART NCT04142515 | Centre Hospitalier Universitaire de Nīmes | — |
| Active Not Recruiting | MEthotrexate Versus TOcilizumab for Treatment of GIant Cell Arteritis: a Multicenter, Randomized, Controlled T NCT03892785 | Centre Hospitalier Universitaire Dijon | Phase 3 |
| Completed | Evaluation of PET/CT of Cephalic Arteries for the Diagnosis of Giant Cell Arteritis NCT05246540 | Centre Hospitalier Universitaire Dijon | — |
| Completed | Comparison of 22Mhz and 18Mhz High-frequency Probes for the Ultrasound Study of Temporal Arteries in Patients NCT04204512 | University Hospital, Brest | — |
| Completed | Use of Gallium-68 HA-DOTATATE PET/CT in Giant Cell Arteritis (GCA) NCT03812302 | University of Alberta | Phase 2 |
| Completed | A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Tocilizumab (TCZ) Administered to Pa NCT03923738 | Hoffmann-La Roche | Phase 1 |
| Terminated | Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune Disease NCT03656627 | Alliance Foundation Trials, LLC. | Phase 1 |
| Active Not Recruiting | PET Imaging of Giant Cell and Takayasu Arteritis NCT04071691 | University of Cambridge | — |
| Terminated | TARGET GCAT Registry NCT04049071 | University of Leeds | — |
| Completed | Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis NCT03482479 | University of Pennsylvania | Phase 2 |
| Completed | A Placebo-controlled Phase 2 Trial to Investigate the Safety and Efficacy of Secukinumab in Giant Cell Arterit NCT03765788 | Novartis Pharmaceuticals | Phase 2 |
| Completed | Giant Cell Arteritis Treatment With Ultra-short Glucocorticoids and Tocilizumab NCT03745586 | Insel Gruppe AG, University Hospital Bern | Phase 1 / Phase 2 |
| Completed | Tocilizumab Plus a Short Prednisone Taper for GCA NCT03726749 | Massachusetts General Hospital | Phase 4 |
| Terminated | Evaluation of Efficacy and Safety of Sarilumab in Patients With GCA NCT03600805 | Sanofi | Phase 3 |
| Completed | KPL-301 for Subjects With Giant Cell Arteritis NCT03827018 | Kiniksa Pharmaceuticals, Ltd. | Phase 2 |
| Completed | Assessment of Giant Cell Arteritis Medical Practices in France NCT03658889 | Chugai Pharma France | — |
| Completed | Journey of Patients With Vasculitis From First Symptom to Diagnosis NCT03410290 | University of Pennsylvania | — |
| Completed | An Extension Study to Evaluate Long-Term Safety of Subcutaneous (SC) Tocilizumab in Participants With Giant Ce NCT03202368 | Hoffmann-La Roche | Phase 3 |
| Withdrawn | A Study to Evaluate Efficacy and Safety of Subcutaneous Abatacept With Steroid Treatment Compared to Steroid T NCT03192969 | Bristol-Myers Squibb | Phase 3 |
| Terminated | Giant Cell Arteritis and Anakinra Trial NCT02902731 | University Hospital, Caen | Phase 3 |
| Unknown | Polymyalgia Rheumatica and Giant Cell Arteritis NCT02985424 | Svendborg Hospital | — |
| Terminated | Ustekinumab for the Treatment of Giant Cell Arteritis NCT02955147 | Massachusetts General Hospital | Phase 1 / Phase 2 |
| Recruiting | VCRC Tissue Repository NCT02967068 | University of Pennsylvania | — |
| Completed | Validation of a Diagnostic Algorithm of Giant Cell Arteritis NCT02703922 | Poitiers University Hospital | N/A |
| Completed | Giant Cell Arteritis and PET Scan (GAPS) Study NCT02771483 | Royal North Shore Hospital | — |
| Terminated | Efficacy and Safety Study of Sirukumab in Patients With Giant Cell Arteritis NCT02531633 | GlaxoSmithKline | Phase 3 |
| Unknown | Giant Cell Arteritis: Improving Use of Ultrasound Evaluation NCT02523625 | University of Oxford | — |
| Unknown | Study of Circulating Microparticles in Giant Cell Arteritis NCT02333708 | University Hospital, Caen | — |
| Unknown | PatientSpot Formerly Known as ArthritisPower NCT03840928 | Global Healthy Living Foundation | — |
| Unknown | Tocilizumab Dose-tapering and Interruption in Patients With Giant Cell Arteritis Achieving the Clinical Remiss NCT03244709 | Hospital of Prato | Phase 4 |
| Completed | FDG Uptake in Large-Vessel Giant Cell Arteritis After Short-term, High-Dose Steroid Treatment NCT03285945 | University of Aarhus | — |
| Completed | Diagnostic Accuracy of FDG PET/CT of Cranial Arteries in GCA NCT03409913 | University of Aarhus | — |
| Completed | Evaluation of Ultrasound and PET/CT in the Diagnosis and Monitoring of Giant Cell Arteritis NCT03765424 | University of Aarhus | — |
| Recruiting | Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis NCT02257866 | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | — |
| Completed | VCRC Patient Contact Registry Patient-Reported Data Validation Study NCT02190942 | University of South Florida | — |
| Completed | Evaluation of Tocilizumab as an add-on Therapy to Corticoids in Giant Cell Arteritis: Proof of Concept Study. NCT01910038 | Centre Hospitalier Universitaire Dijon | Phase 2 |
| Completed | An Efficacy and Safety Study of Tocilizumab (RoActemra/Actemra) in Participants With Giant Cell Arteritis (GCA NCT01791153 | Hoffmann-La Roche | Phase 3 |
| Completed | Educational Needs of Patients With Systemic Vasculitis NCT02190929 | University of South Florida | — |
| Completed | Prospective Follow-up Study of the Aortic Diameter in Patients With Giant Cell Arteritis NCT01588483 | Universitaire Ziekenhuizen KU Leuven | — |
| Completed | Vasculitis Illness Perception (VIP) Study NCT02190916 | University of South Florida | — |
| Completed | Tocilizumab for Patients With Giant Cell Arteritis NCT01450137 | Insel Gruppe AG, University Hospital Bern | Phase 2 |
| Completed | Reproductive Health in Men and Women With Vasculitis NCT02176070 | University of South Florida | — |
| Unknown | American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) Diagnostic and Classification NCT01066208 | University of Oxford | — |
| Recruiting | One-Time DNA Study for Vasculitis NCT01241305 | University of Pennsylvania | — |
| Completed | Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis NCT01795456 | The Cleveland Clinic | — |
| Completed | Temporal Artery Biopsy vs ULtrasound in Diagnosis of GCA (TABUL) NCT00974883 | University of Oxford | — |
| Unknown | Steroids Pharmacokinetics and the Response to Prednisone Therapy in Giant Cell Arteritis NCT01400464 | University Hospital, Caen | Phase 4 |
| Completed | Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu's Arteritis NCT00556439 | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Phase 2 |
| Completed | HECTHOR: Humira to Spare Steroids in Giant Cell Arteritis NCT00305539 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Recruiting | Clinical and Immunogenetic Characterization of Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR) NCT04102930 | University of Leeds | — |
| Terminated | A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Giant Cell Arteritis NCT00076726 | Centocor, Inc. | Phase 2 |
| Completed | Hydroxychloroquine in Giant Cell Arteritis NCT00430807 | University Hospital, Toulouse | Phase 3 |
| Completed | Prevention of Glucocorticoid-Induced Osteoporosis in Rheumatic Diseases: Alendronate Versus Alfacalcidol. NCT00138983 | UMC Utrecht | Phase 3 |
| Unknown | Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases NCT00006055 | Fairview University Medical Center | N/A |
| Completed | Phase II Randomized Study of Glucocorticoids With or Without Methotrexate for Treatment of Giant Cell Arteriti NCT00004686 | The Cleveland Clinic | Phase 2 |