| Withdrawn | Study of Deucravacitinib for Refractory Adults With Dermatomyositis/Juvenile Dermatomyositis Myositis, Dermatomyositis | Phase 2 | 2025-11-21 |
| Withdrawn | A Clinical Trial to Evaluate Safety of Gusacitinib in Patients With Systemic Lupus Erythematosus (SLE) or Lupu Systemic Lupus Erythematosus | Phase 1 | 2025-01-22 |
| Recruiting | The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (S Systemic Lupus Erythematosus, Cardiovascular Disease, Premature Atherosclerosis | Phase 2 | 2023-12-07 |
| Recruiting | Natural History of Inflammatory Muscle Diseases Inflammation In Skeletal Muscle | — | 2023-06-01 |
| Recruiting | Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophospham Systemic Lupus Erythematosus (Sle), Primary Ovarian Insufficiency (Poi) | — | 2023-03-03 |
| Completed | Natural History and Pathogenesis of Alopecia in Children and Adults Hair Loss | — | 2022-09-19 |
| Completed | Natural History of Coronavirus Disease (COVID-19) in Systemic Autoimmune Diseases Systemic Autoimmune Diseases | — | 2021-02-11 |
| Completed | Genomic Effects of Glucocorticoids in Patients With Systemic Lupus Erythematosus Systemic Lupus Erythematous (SLE) | EARLY_Phase 1 | 2020-03-04 |
| Terminated | Topical Ruxolitinib for Cutaneous Chronic Graft Versus Host Disease (cGVHD) Graft Versus Host Disease, JNS Kinase, Topical Administration | Phase 2 | 2018-11-19 |
| Recruiting | Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Still's Disease, Adult-Onset, Systemic Inflammation, Arthritis | — | 2018-05-21 |
| Completed | Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Systemic Lupus Erythematosus Systemic Lupus Erythematosus | Phase 1 | 2015-08-28 |
| Recruiting | Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic Disease Rheumatic Disease | — | 2015-08-16 |
| Recruiting | Studies of Dermatologic Diseases Biospecimen Acquisition Protocol Dermatologic Conditions, Healthy Volunteers, Normal Volunteers | — | 2015-06-19 |
| Completed | Role of PPAR-y Agonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE) Systemic Lupus Erythematosus | Phase 1 / Phase 2 | 2015-06-18 |
| Active Not Recruiting | Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries Rheumatoid Arthritis, Ankylosing Spondylitis | — | 2014-10-24 |
| Recruiting | Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis Takayasu's Arteritis, Giant Cell Arteritis, Polyarteritis Nodosa | — | 2014-09-29 |
| Completed | Omalizumab for Lupus Systemic Lupus Erthematosus, Sjogren's Syndrome | Phase 1 | 2014-01-08 |
| Completed | Anakinra for Inflammatory Pustular Skin Diseases Sneddon-Wilkinson, Acrodermatitis Continua of Hallopeau, Pustular Psoriasis | Phase 2 | 2013-07-22 |
| Completed | Rilonacept for Deficiency of the Interleukin-1 Receptor Antagonist (DIRA) DIRA | Phase 2 | 2013-02-12 |
| Recruiting | Effects of Treatments on Atopic Dermatitis Eczema, Dermatitis, Skin Diseases, Genetic | Phase 2 | 2012-09-18 |
| Completed | Anakinra for Behcet s Disease Autoimmune Connective Tissue Disorder, Immune System Diseases | Phase 1 / Phase 2 | 2011-09-01 |
| Terminated | Genetic Basis of Primary Immunodeficiencies Immunologic Deficiency Syndrome | — | 2011-08-21 |
| Recruiting | Natural History and Development of Spondyloarthritis Arthritis, Spondylitis, Ankylosing | — | 2011-08-12 |
| Completed | Bisphosphonate Users Radiographic Characteristics of the Hip (BURCH) Study Osteoporosis, Bone Diseases, Metabolic, Hip Fractures | — | 2011-05-04 |
| Withdrawn | A Pilot Study of XOMA 052 in Familial Cold Autoinflammatory Syndrome / Muckle-Wells Syndrome and Behcet's Dise Muckle Wells Syndrome, Autoinflammatory, Behcet's Disease | Phase 1 / Phase 2 | 2010-08-27 |
| Completed | Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu's Arteritis Takayasu's Arteritis, Giant Cell Arteritis | Phase 2 | 2008-12-01 |
| Completed | Insulin Resistance and Atherosclerosis in Women With Lupus Systemic Lupus Erythematosus, Insulin Resistance, Atherosclerosis | — | 2007-10-11 |
| Unknown | The Effects of Exercise Versus Inactivity on People With Mitochondrial Muscle Disease Mitochondrial Myopathy | Phase 2 | 2007-06-01 |
| Completed | A Pilot of Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity Healthy Volunteers, Fungal Infections, Bacterial Infections | Phase 1 | 2007-05-25 |
| Completed | Progression of Spinal Fusion in Ankylosing Spondylitis Ankylosing Spondylitis | — | 2004-12-03 |
| Completed | Interleukin-1 Trap to Treat Autoinflammatory Diseases Inflammation, Familial Mediterranean Fever, Still's Disease, Adult-Onset | Phase 2 | 2004-10-01 |
| Completed | Osteoarthritis Initiative (OAI): A Knee Health Study Osteoarthritis, Knee Osteoarthritis | — | 2004-02-01 |
| Completed | Electromagnetic Treatment For Bone Loss After Forearm Fracture Bone Disease, Metabolic, Osteopenia, Osteoporosis, Post-Traumatic | Phase 1 / Phase 2 | 2003-11-01 |
| Completed | Protective Brace to Prevent Hand and Arm Injuries Cumulative Trauma Disorders, Carpal Tunnel Syndrome | N/A | 2003-11-01 |
| Terminated | Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease Nervous System Malformations, Arthropathy, Neurogenic, Urticaria | Phase 1 / Phase 2 | 2003-09-01 |
| Completed | Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study Ankylosing Spondylitis | — | 2003-06-19 |
| Completed | Treating Rheumatoid Arthritis With Tripterygium Wilfordi Hook F or Sulfasalazine Rheumatoid Arthritis | Phase 2 | 2003-06-01 |
| Recruiting | Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases Including Juvenile Derm Autoinflammatory Disease, Juvenile Dermatomyositis | — | 2003-05-09 |
| Completed | Genetic Determinants of Ankylosing Spondylitis Severity Ankylosing Spondylitis | — | 2003-03-24 |
| Completed | Clinically Important Changes in Rheumatoid Arthritis Rheumatoid Arthritis | — | 2003-03-18 |
| Completed | Gabapentin in Fibromyalgia Trial (GIFT) Fibromyalgia | Phase 2 / Phase 3 | 2003-03-01 |
| Unknown | 3-D Laser Imaging to Analyze Neck Movement Neck Pain, Manipulation, Spinal | — | 2003-01-01 |
| Terminated | Image Guided System for Orthopaedic Surgery Orthopaedic Trauma, Hip Fracture | Phase 2 | 2002-12-01 |
| Completed | Monoclonal Antibody Treatment for Systemic Lupus Erythematosus Systemic Lupus Erythematosus | Phase 1 | 2002-09-02 |
| Completed | Nitroglycerin Ointment for Preventing Bone Loss in Postmenopausal Women Osteoporosis, Osteopenia | Phase 3 | 2002-07-01 |
| Completed | Role of Antibodies in Cognitive Dysfunction in Patients With Systemic Lupus Erythematosus Systemic Lupus Erythematosus | — | 2002-07-01 |
| Terminated | Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients Scleroderma, Systemic Sclerosis | Phase 1 | 2002-07-01 |
| Completed | Management of Compartment Syndrome With Ultrafiltration Compartment Syndrome | Phase 1 | 2002-06-01 |
| Completed | Infliximab (Remicade ) to Treat Dermatomyositis and Polymyositis Dermatomyositis, Polymyositis | Phase 2 | 2002-04-10 |
| Completed | The Role of Cytokines on Growth Hormone Suppression in Premenopausal Women With Rheumatoid Arthritis and the E Rheumatoid Arthritis, Healthy | Phase 2 | 2002-04-01 |
| Terminated | Blood Component Collection From Patients With Rheumatic or Kidney Disease and Healthy Volunteers Rheumatic Diseases, Healthy Volunteers | — | 2002-02-13 |
| Terminated | Infliximab to Treat Children With Juvenile Rheumatoid Arthritis Juvenile Rheumatoid Arthritis | Phase 2 | 2002-01-01 |
| Completed | Positron Emission Tomography (PET) to Locate Areas of White Blood Cell Activity Lupus Erythematosus, Systemic | — | 2002-01-01 |
| Recruiting | Studies of the Natural History of Rheumatic Diseases Rheumatic Diseases, Arthritis | — | 2001-10-03 |
| Completed | Effects of Exercise Poles on Older Adults During Exercise Walking Movement Disorders, Aging | Phase 1 / Phase 2 | 2001-09-01 |
| Completed | Muscle Strengthening Device for Knee Osteoarthritis Osteoarthritis | Phase 2 | 2001-09-01 |
| Completed | Positron Emission Tomography and Magnetic Resonance Imaging to Evaluate Synovial Blood Flow in Rheumatoid Arth Rheumatoid Arthritis | Phase 1 | 2001-04-01 |
| Completed | Humanized LL2IGG to Treat Systemic Lupus Erythematosus Systemic Lupus Erythematosus | Phase 1 | 2001-02-01 |
| Completed | Registry for African Americans With Early Rheumatoid Arthritis Rheumatoid Arthritis | — | 2001-01-01 |
| Completed | Study of Arthritis and Related Conditions Rheumatoid Arthritis | — | 2000-10-03 |
| Completed | Consortium for the Longitudinal Evaluation of African Americans With Early Rheumatoid Arthritis (The CLEAR Reg Rheumatoid Arthritis | — | 2000-09-01 |
| Completed | Scleroderma Registry Systemic Sclerosis, Scleroderma | — | 2000-09-01 |
| Completed | Infliximab for the Treatment of Early Rheumatoid Arthritis Rheumatoid Arthritis | Phase 2 | 2000-09-01 |
| Completed | Scalp Psoriasis Treatment With a Fiber Optic Comb Psoriasis | Phase 1 / Phase 2 | 2000-08-01 |
| Completed | Etanercept for Wegener's Granulomatosis Wegener's Granulomatosis | Phase 2 / Phase 3 | 2000-06-01 |
| Completed | Oral Type I Collagen for Relieving Scleroderma Scleroderma, Connective Tissue Diseases | Phase 2 | 2000-04-01 |
| Completed | Safety and Effectiveness of h5G1.1-mAb for Dermatomyositis Dermatomyositis | Phase 2 | 2000-04-01 |
| Completed | Treatment of Psoriasis With Parathyroid Hormone Plaque Psoriasis | Phase 1 / Phase 2 | 2000-01-01 |
| Completed | High-Dose Intravenous (IV) Cyclophosphamide Versus Monthly IV Cyclophosphamide Lupus Erythematosus, Systemic | Phase 3 | 2000-01-01 |
| Completed | Blocking Tumor Necrosis Factor in Ankylosing Spondylitis Spondylitis, Ankylosing | Phase 2 | 1999-10-01 |
| Terminated | Low-Dose Hormone Replacement Therapy and Alendronate for Osteoporosis Osteopenia, Osteoporosis | Phase 3 | 1999-10-01 |
| Completed | Genetics of Ankylosing Spondylitis Spondylitis, Ankylosing Spondylitis | — | 1999-09-01 |
| Completed | dnaJ Peptide for Relieving Rheumatoid Arthritis Rheumatoid Arthritis | Phase 2 | 1999-09-01 |
| Unknown | Genetics of Fibromyalgia Fibromyalgia, Irritable Bowel Syndrome, Chronic Fatigue Syndrome | — | 1999-09-01 |
| Completed | BG9588 (Anti-CD40L Antibody) to Treat Lupus Nephritis Glomerulonephritis, Membranoproliferative, Lupus Nephritis | Phase 2 | 1999-06-01 |
| Completed | Prognostic Indicators and Determinants of the 2-5 Year Outcome in a Cohort of Early Synovitis Patients Arthritis, Reactive, Arthritis, Rheumatoid, Synovitis | — | 1998-08-01 |
| Completed | Genetics of Rheumatoid Arthritis Rheumatoid Arthritis | — | 1998-07-07 |
| Completed | Osteoporosis Prevention in Preadolescent Girls Osteoporosis | Phase 2 | 1998-07-01 |
| Completed | Methotrexate Alone Versus Combination of Methotrexate and Subcutaneous Fludarabine for Severe Rheumatoid Arthr Arthritis, Rheumatoid, Synovitis | Phase 2 | 1998-06-01 |
| Completed | The Acquisition of Blood and Skin Samples From Normal Volunteers to Support Research Activities on Dermatologi Healthy Volunteer, Dermatologic Diseases, Systemic Diseases | — | 1998-01-15 |
| Completed | Cyclophosphamide and Fludarabine to Treat Lupus Nephritis Glomerulonephritis, Lupus Nephritis, Systemic Lupus Erythematosus | Phase 1 | 1998-01-01 |
| Completed | Evaluation and Treatment of Patients With Dermatologic Diseases Dermatologic Diseases, Systemic Diseases With Cutaneous Manifestations | — | 1996-08-22 |
| Completed | Tidal Lavage in Knee Osteoarthritis Osteoarthritis, Knee | Phase 2 | 1995-07-01 |
| Completed | A Controlled Trial of Intermittent Fludarabine for Psoriatic Arthritis Arthritis, Psoriatic, Psoriasis | Phase 2 | 1995-06-01 |
| Completed | Methimazole to Treat Polymyositis and Dermatomyositis Dermatomyositis, Polymyositis | Phase 2 | 1995-06-01 |
| Completed | Study of Psoriatic Arthritis Psoriasis, Psoriatic Arthritis | — | 1995-03-01 |
| Completed | Juvenile Rheumatoid Arthritis Research Registry Juvenile Rheumatoid Arthritis | — | 1994-10-01 |
| Completed | National Registry for Ichthyosis and Related Disorders Darier Disease, Hailey-Hailey Disease, Hyperkeratosis, Epidermolytic | — | 1994-09-01 |
| Completed | The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis Arthritis, Arthritis, Reactive, Arthritis, Rheumatoid | — | 1994-08-01 |
| Completed | Steroid Hormones, TH1/TH2 Cytokines and Reproductive Status Arthritis, Rheumatoid, Healthy, Pregnancy | — | 1994-08-01 |
| Recruiting | Study of Systemic Lupus Erythematosus Systemic Lupus Erythematosus | — | 1994-02-10 |
| Completed | Improving Functional Recovery After Hip Fracture Unilateral Hip Fracture | Phase 3 | 1993-07-01 |
| Completed | Genetic and Family Studies of Inherited Muscle Diseases Dermatomyositis, Glycogen Storage Disease Type II, Glycogen Storage Disease Type VII | — | 1993-05-01 |
| Completed | Study of Silicone-Associated Connective Tissue Diseases Autoimmune Diseases, Connective Tissue Diseases, Scleroderma, Circumscribed | — | 1992-11-01 |
| Completed | Study and Treatment of Inflammatory Muscle Diseases Dermatomyositis, Polymyositis | — | 1992-01-10 |
| Completed | Genetic and Immune Studies of Rheumatoid Arthritis and Related Conditions Arthritis, Psoriatic, Autoimmune Diseases, Joint Diseases | — | 1991-12-01 |
| Completed | Isotretinoin in Preventing Skin Cancer Melanoma (Skin), Non-melanomatous Skin Cancer | N/A | 1991-06-01 |
| Completed | Impact of Exercise on Older Persons With Osteoarthritis Osteoarthritis | Phase 2 | 1983-12-01 |
| Terminated | Prevention of Steroid-Induced Osteoporosis in Children Osteoporosis | Phase 1 / Phase 2 | — |