NCT05865054

Vascular MRI Evaluation in Giant Cell Arteritis (VEGA)

A Longitudinal Study of Orbital and Cranial Vessel Wall MRI in Giant Cell Arteritis by the Vascular MRI Evaluation in Giant Cell Arteritis (VEGA) Collaborative

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 400 (estimated)
• Sponsor: University of Pennsylvania · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Accepted

Summary

The research study is being conducted to determine the utility of magnetic resonance imaging (MRI) in identifying inflammation of arteries supplying blood to the head, brain, and eyes. The target population includes patient with suspected giant cell arteritis (GCA; temporal arteritis).

Detailed description

After signing the consent form, participants will complete an MRI scan within 2 weeks of enrollment and fill out questionnaires related to their disease. Follow up visits and MRI scans may occur at 6-months after the initial MRI scan or at the time of relapse.

Conditions

• Giant Cell Arteritis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Magnetic Resonance Imaging (MRI)	Combined orbital and cranial vessel wall MRI

Timeline

• Start date: 2020-07-29
• Primary completion: 2030-07-01
• Completion: 2033-07-01
• First posted: 2023-05-18
• Last updated: 2025-09-19

Locations

4 sites across 3 countries: United States, Canada, Germany