| Not Yet Recruiting | CD5CAR-NK Cells for Refractory Invasive Mold Disease NCT07454122 | Fundacion Clinic per a la Recerca Biomédica | Phase 1 |
| Not Yet Recruiting | Fungal Vascular Graft Infections, French Multicenter Retrospective Study NCT07143409 | University Hospital, Bordeaux | — |
| Enrolling By Invitation | Rezafungin Prophylaxis in Liver Transplant NCT06774144 | Fernanda P Silveira, MD, MS | Phase 3 |
| Active Not Recruiting | Liver Cirrhosis Patients With Invasive Pulmonary Aspergillosis: in Depth Understanding Clinical Host Risk Fact NCT07238114 | Universitaire Ziekenhuizen KU Leuven | — |
| Not Yet Recruiting | Isavuconazole in Critically Ill Patients: Efficacy and Safety NCT07080359 | Shanghai 10th People's Hospital | — |
| Recruiting | Pharmacogenomics for Better Treatment of Fungal Infections Clinical Trial NCT06510699 | The University of Queensland | Phase 2 |
| Recruiting | Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDS NCT05814432 | Federal University of Health Science of Porto Alegre | Phase 3 |
| Not Yet Recruiting | Individualized First Maintenance Doses of Voriconazole Through a Multiparametric Algorithm NCT06582186 | University Hospital, Grenoble | Phase 4 |
| Not Yet Recruiting | Topical Application of Essential Oils to Treat Onchomycosis NCT06417983 | Medical Life Care Planners, LLC | — |
| Recruiting | Retrospective Observational Study on Infective Complications and Outcome of Patients With ALL Treated With INO NCT06025682 | Gruppo Italiano Malattie EMatologiche dell'Adulto | — |
| Unknown | The Impact of Rapid Diagnostic Methods in the Diagnosis of Fungal Infections in Intensive Care Units of Assiut NCT05876962 | Assiut University | — |
| Unknown | The Assessment of Antimicrobial Peptides Against Fungal Infection NCT05368948 | Assiut University | — |
| Completed | Relationship Between Fungal Colonization and Severe Bronchopulmonary Dysplasia NCT05152875 | Centre Hospitalier Sud Francilien | — |
| Completed | The Role of Interferon-gamma in Immune Responses to Invasive Candidiasis NCT05235711 | Mayo Clinic | — |
| Completed | An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection NCT05202366 | CAGE Bio Inc. | — |
| Completed | Multicenter Cohort Study of Invasive Fungal Filamentous Fungal Infections in Liver Transplant Patients NCT05150327 | University Hospital, Strasbourg, France | — |
| Unknown | Microbiota in Skin and Mucosa of Patients With Inflammatory Skin Diseases NCT04215458 | Zealand University Hospital | N/A |
| Completed | A Trial Involving Treatment of BB2603 in Subjects With Distal Subungual Onychomycosis of the Toenail NCT04188574 | Blueberry Therapeutics | Phase 2 |
| Completed | COVID-19 Associated Pulmonary Aspergillosis (CAPA) and Other Invasive Fungal Infections (IFI) NCT04818853 | University of Alabama at Birmingham | — |
| Completed | Immune Profiles in CF Fungal Infection NCT04476758 | University of Alabama at Birmingham | — |
| Unknown | Fungal Infection in Patients in Intensive Care Units NCT04684342 | Assiut University | N/A |
| Completed | Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in A NCT04368559 | Mundipharma Research Limited | Phase 3 |
| Completed | Effect of Administration of Combined Enteral Lactoferrin and Probiotic On Invasive Fungal Infections In Preter NCT05283278 | Ain Shams University | Phase 1 |
| Completed | Itraconazole Oral Absorption NCT04035187 | University of Maryland, Baltimore | Phase 4 |
| Unknown | Escalation Antifungal Prophylaxis for Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation NCT04273178 | Shanghai Jiao Tong University School of Medicine | Phase 2 |
| Completed | ADME Study of [14C]-Ibrexafungerp in Healthy Male Subjects NCT04307082 | Scynexis, Inc. | Phase 1 |
| Terminated | Safety and Pharmacokinetics of Rezafungin NCT04117607 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 1 |
| Completed | A Drug-Drug Interaction Study of CYP3A4 Inhibition and Pan-CYP Induction on APX001 NCT04166669 | Basilea Pharmaceutica | Phase 1 |
| Recruiting | Posaconazole Pharmacokinetics in Patients Receiving Chemotherapy or Stem Cell Transplants NCT03717623 | Melbourne Health | Phase 4 |
| Unknown | Study to Optimize the Use of New Antibiotics NCT03941951 | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | N/A |
| Completed | The PK/PD of Deoxycholic Acid Amphotericin B in Invasive Fungal Infection Patients With Sepsis/Septic Shock NCT05642624 | Southeast University, China | — |
| Unknown | Efflux Pump Mediated Azole Resistance in Candida Albicans NCT03659162 | Assiut University | — |
| Recruiting | PTX3-targeted Antifungal Prophylaxis NCT03828773 | Bochud Pierre-Yves | N/A |
| Completed | Topical Amphotericin B in 30% Dimethylsulphoxide in Treating of Non-dermatophytes Onychomycosis NCT03814343 | Mahidol University | Phase 4 |
| Completed | Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis NCT03667690 | Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | Phase 3 |
| Unknown | Fungal Infections in Patients With Hematological Malignancies NCT03650439 | Assiut University | — |
| Completed | Empiric Therapy of Patients With Persistent Fever and Agranulocytosis Using Caspofungin NCT03857399 | Cttq | Phase 2 |
| Completed | Ampholipad Real-World Data in Taiwan NCT03641131 | Taiwan Liposome Company | — |
| Completed | A Study to Evaluate the Appropriateness of the Voriconazole Dosing Regimen NCT03760276 | Seoul National University Hospital | Phase 1 |
| Completed | A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy NCT04804059 | Basilea Pharmaceutica | Phase 1 |
| Unknown | Universal Prophylaxis Versus Pre-emptive Therapy With Posaconazole Post-Lung Transplant NCT03561415 | Bayside Health | Phase 2 |
| Completed | Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic NCT03434704 | Ciceri Fabio | Phase 2 |
| Completed | Posaconazole Prophylaxis During ATG Treatment for hMDS/AA Patients NCT03318159 | Seoul National University Hospital | Phase 2 |
| Completed | Pharmacokinetics of Caspofungin NCT03399032 | Medical University of Lublin | — |
| Completed | CYP2C19 Genotype-Specific Dosing Plus TDM on Reaching Therapeutic Voriconazole Blood Levels NCT03731169 | University Health Network, Toronto | Phase 4 |
| Completed | Pharmacokinetics and Safety of Intravenous Posaconazole (MK-5592) in Chinese Participants at High Risk for Inv NCT03336502 | Merck Sharp & Dohme LLC | Phase 1 |
| Unknown | Systemic Fungal Infections in ICU Patients NCT03292224 | Assiut University | — |
| Completed | Safety, Pharmacokinetics, Bioavailability, Food Effect, Drug-Drug Interaction Study of APX001 Administered Ora NCT02957929 | Basilea Pharmaceutica | Phase 1 |
| Completed | CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidias NCT02734862 | Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | Phase 2 |
| Completed | Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to He NCT02956499 | Basilea Pharmaceutica | Phase 1 |
| Completed | Vfend Special Investigation For Prophylaxis NCT02674685 | Pfizer | — |
| Unknown | The Study of Voriconazole Trough Level in the First Two Weeks After Administration in King Chulalongkorn Memor NCT03260634 | Chulalongkorn University | — |
| Completed | Pharmacokinetics and Safety of Oral Posaconazole (MK-5592)Tablets in Chinese Participants at High Risk for Inv NCT02387983 | Merck Sharp & Dohme LLC | Phase 1 |
| Terminated | Study to Evaluate Outcomes of Patients Receiving Treatment for Wound Care, Pain Management or Surface Skin Sca NCT02445235 | Bracane Company | — |
| Completed | MT2013-37R: Voriconazole Monitoring in Pediatric Stem Cell Transplant Patients NCT02227797 | Masonic Cancer Center, University of Minnesota | Phase 1 |
| Completed | Fungal Biomarkers to Reduce Duration of Empirical Antifungal Therapy: a Randomized Comparative Study (STAFE) NCT02154178 | University Hospital, Lille | N/A |
| Completed | Effect of Inflammation on Voriconazole Concentration NCT02074462 | University Medical Center Groningen | — |
| Completed | Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor NCT01503515 | Children's Oncology Group | Phase 3 |
| Terminated | A Pharmacokinetic Analysis of Posaconazole in Lung Transplant Recipients (MK-5592-105) NCT01667107 | Merck Sharp & Dohme LLC | Phase 4 |
| Completed | Empirical Versus Preemptive Antifungal Therapy NCT01288378 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 3 |
| Unknown | Investigation of Clinical Relevance of β-D-Glucan Tests in Patients With Invasive Fungal Infection (IFI) NCT01490138 | Ruijin Hospital | — |
| Completed | A Trial Comparing Efficacy and Safety of Voriconazole Administered With Therapeutic Drug Monitoring vs. Standa NCT01416025 | Johns Hopkins University | Phase 4 |
| Completed | Anidulafungin vs Amphotericin B Safety in High Risk Hepatic Transplant Recipients NCT01303549 | Fundacion SEIMC-GESIDA | Phase 4 |
| Completed | Pharmacokinetic Analysis of Posaconazole in Lung Transplant Recipients NCT01419678 | University of Pittsburgh | N/A |
| Completed | Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoin NCT01371656 | Children's Oncology Group | Phase 3 |
| Completed | Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemother NCT01307579 | Children's Oncology Group | Phase 3 |
| Completed | Pharmacokinetic, Safety and Efficacy of Intermittent Application of Caspofungin for Antifungal Prophylaxis NCT01318148 | Werner J. Heinz | Phase 2 |
| Completed | Pharmacokinetics/Pharmacodynamics (PK/PD) of Fluconazole in Children on Extracorporeal Membrane Oxygenation (E NCT01169402 | Michael Cohen-Wolkowiez | Phase 1 |
| Completed | Study of Cyclodextrin (SBECD) and Voriconazole Blood Concentrations During Continuous Dialysis NCT01101386 | University of Colorado, Denver | — |
| Completed | Pharmacokinetics, Safety, and Tolerability of Intravenous Posaconazole Solution Followed by Oral Posaconazole NCT01075984 | Merck Sharp & Dohme LLC | Phase 1 |
| Completed | Effect of Weight and/or Obesity on Caspofungin Drug Concentrations NCT01062165 | Texas Tech University Health Sciences Center | Phase 4 |
| Completed | Pharmacokinetics of Posaconazole Prophylaxis in Acute Leukemia NCT00936117 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Beta Glucan Assay in Patients Receiving Voriconazole Prophylaxis NCT00904995 | M.D. Anderson Cancer Center | Phase 3 |
| Completed | Seifem Surveillance of Antifungal Combination Therapy In Hematologic Italian Centers NCT00906633 | University Hospital, Udine, Italy | — |
| Completed | Pharmacokinetic Study of Posaconazole Boosted Fosamprenavir NCT00817765 | Radboud University Medical Center | Phase 1 |
| Completed | Posaconazole Treatment of Invasive Fungal Infection (IFI) (P05551) NCT00811642 | Merck Sharp & Dohme LLC | Phase 3 |
| Withdrawn | Safety of hLF1-11 for the Treatment of Infectious Complications Among HSCT Recipients NCT00430469 | AM-Pharma | Phase 1 / Phase 2 |
| Completed | TMC125-TiDP2-C187: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Interaction Between TMC125 a NCT00740389 | Tibotec Pharmaceuticals, Ireland | Phase 1 |
| Completed | A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infectio NCT00717860 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | A Study of Caspofungin Acetate (MK0991) for the Treatment of Esophageal Candidiasis or Invasive Candidiasis in NCT00635648 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Oral Posaconazole in High Risk Patients With Gastrointestinal Dysfunction (Study P05115) NCT00686543 | Merck Sharp & Dohme LLC | Phase 4 |
| Completed | Alternate Day Micafungin: A PK Study in Pediatric Patients NCT00842504 | Children's Hospital Medical Center, Cincinnati | Phase 1 |
| Terminated | An Assessment of Voriconazole Pharmacokinetics and Pharmacogenetics in Liver Transplant Recipients - Pilot Stu NCT00371605 | University of Pittsburgh | — |
| Terminated | ProphyALL - Study on the Safety of Liposomal Amphotericin B to Prevent Antifungal Infections in Elderly Patien NCT00386997 | Gilead Sciences | Phase 4 |
| Completed | Evaluate the Safety and Efficacy of Caspofungin Acetate as Empirical Therapy in Chinese Adults With Persistent NCT00548080 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Emerging Invasive Fungal Infections in Critically Ill Patients NCT04647539 | University Hospital, Montpellier | — |
| Completed | Fluconazole Pharmacokinetics in Infants NCT00514358 | Children's Hospital of Philadelphia | — |
| Completed | Invasive Fungal Infections Surveillance Initiative NCT00177944 | University of Pittsburgh | — |
| Completed | A 28 - 90 Days Study to Evaluate the Safety, Tolerability, and Efficacy of Caspofungin Injection as Empirical NCT00379964 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Assessment of Voriconazole Penetration Into the Brain by Fluorine-Magnetic Resonance Spectroscopy NCT00136968 | Pfizer | Phase 1 |
| Terminated | Limited Access Protocol of Posaconazole in Invasive Fungal Infections Study PO2095 NCT00177749 | University of Pittsburgh | Phase 4 |
| Completed | Open, Pharmacokinetic Study of Caspofungin Acetate in Immunocompromised Young Children With Febrile Neutropeni NCT00292071 | Merck Sharp & Dohme LLC | Phase 2 |
| Completed | Granulocyte Transfusions in Hematological Patients With Febrile Neutropenia NCT02544230 | Sorveglianza Epidemiologica Infezioni Fungine Emopatie Maligne | — |
| Unknown | Prophylaxis With Caspofungin in High-Risk Liver Transplantation NCT00333645 | Grupo de Estudio de Infecciones en Transplantados | Phase 2 |