Trials / Conditions / Early-stage Breast Cancer

Early-stage Breast Cancer

96 registered clinical trials studyying Early-stage Breast Cancer — 36 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	BAriaTric Surgery After Breast Cancer Treatment (BATS) NCT03946423	Masonic Cancer Center, University of Minnesota	N/A
Recruiting	Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer NCT06768931	Sun Yat-sen University	Phase 2
Not Yet Recruiting	Cryoablation Versus Lumpectomy in Early-Stage Breast Cancer NCT07483996	Franciscus Gasthuis & Vlietland (Hospital)	Phase 3
Not Yet Recruiting	Impact of Exercise on Quality of Life of EBC Patients on Treatment With Adjuvant AI With or Without CDK4/6 Inh NCT07215364	Spanish Breast Cancer Research Group	N/A
Not Yet Recruiting	CDK4/6 Inhibitors Combined With Endocrine Therapy for Neoadjuvant Treatment NCT07366112	Peking University People's Hospital	Phase 2
Not Yet Recruiting	Shaving as an Safe Alternative to Frozen Section Analysis NCT07244588	Mark Ezzat Gerges	N/A
Recruiting	Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Brea NCT07211178	Tempus AI	—
Recruiting	Evaluating the Use of a Medication 'Switch' vs Guideline-directed Interventions for Relieving Side Effects of NCT07071038	Dartmouth-Hitchcock Medical Center	Phase 2
Suspended	Pilot Trial of Preop Partial Radiation in Breast Cancer Patients NCT07178665	Rutgers, The State University of New Jersey	Phase 1
Recruiting	ctDNA-Guided De-Escalation of Adjuvant Chemotherapy With Dalpiciclib in HR-Positive/HER2-Negative Breast Cance NCT06970912	Peking University People's Hospital	Phase 2
Recruiting	Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt) NCT06150898	Jules Bordet Institute	Phase 2
Enrolling By Invitation	Multigene Risk Score Combined With Ki-67 Dynamic Assessment in Stratified Neoadjuvant Endocrine Therapy Treatm NCT06650748	Peking University	Phase 2
Recruiting	Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-S NCT06902311	UNC Lineberger Comprehensive Cancer Center	Phase 2
Recruiting	Diagnostic HER2DX-guided Treatment for Patients wIth Early-stage HER2-positive Breast Cancer NCT06446882	Fundacio Clinic Barcelona	N/A
Recruiting	Gut Microbiome, Adverse Effects, and Markers Through MEtabolic Reprogramming NCT06536881	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	N/A
Withdrawn	Evaluation of Hydroxychloroquine to Prevent CIPN NCT05689359	University of Arizona	Phase 2
Recruiting	Portable Scalp Cooling System (PSCS) to Prevent Hair Loss for Breast Cancer Patients (Cooler Heads) NCT06215469	University of California, San Francisco	N/A
Enrolling By Invitation	VISION: Triple Negative Breast Cancer Sample and Clinical Data Acquisition Study NCT06409221	Concr	—
Recruiting	Outcomes and Cosmesis With Whole Breast Irradiation and Boost NCT06295744	University of Wisconsin, Madison	N/A
Recruiting	Paclitaxel-induced Polyneuropathy in Breast Cancer: Early Detection, Risk Factors, Quality of Life and Lifesty NCT06052345	Theodoros Foukakis	—
Active Not Recruiting	Neoadjuvant Pyrotinib in HR-positive and HER2-low High-risk Early Breast Cancer NCT06144944	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Phase 3
Active Not Recruiting	TRADE: Dose Escalation Tolerability of Abemaciclib in HR+ HER2- Early Stage Breast Cancer NCT06001762	Dana-Farber Cancer Institute	Phase 2
Unknown	Percent Weight Change in the Medical Supplement Group of Early Breast Cancer NCT06311357	Department of Medical Services Ministry of Public Health of Thailand	N/A
Recruiting	Breast Cancer Exercise Intervention Study NCT05957068	National Cancer Centre, Singapore	N/A
Recruiting	Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITION-GUIDE) NCT05332561	German Cancer Research Center	Phase 2
Unknown	Effect of Salovum™ and SPC-Flakes™ on Abemaciclib-induced Gastrointestinal Toxicity in Early Breast Cancer NCT06152471	Henrik Lindman	Phase 3
Recruiting	Pyrotinib Plus Capecitabine for Adjuvant Treatment of HER2 Positive Early-stage Breast Cancer NCT06035016	Peking Union Medical College Hospital	—
Recruiting	Evaluating Omission of Granulocyte Colony-stimulating Factors in Breast Cancer Patients Receiving Paclitaxel P NCT05753618	Ottawa Hospital Research Institute	Phase 4
Recruiting	Adjuvant Trastuzumab Plus Neratinib in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Posi NCT05760612	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Phase 3
Recruiting	Cardioprotective Effect of Acute Exercise in Breast Cancer Patients NCT05467111	Technical University of Madrid	N/A
Recruiting	Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy NCT05582499	Fudan University	Phase 2
Recruiting	Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted NCT05559164	Rutgers, The State University of New Jersey	Phase 2
Completed	Preventing Chemotherapy-Induced Peripheral Neuropathy With Acupuncture (PACT Trial) NCT05528263	Dana-Farber Cancer Institute	N/A
Active Not Recruiting	Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant Nerati NCT05252988	Spanish Breast Cancer Research Group	Phase 2
Active Not Recruiting	Study of Quality of Life and Hormone Levels in Premenopausal Participants With Early Breast Cancer Receiving T NCT05377684	Ipsen	—
Recruiting	Cardiometabolic Screening Program NCT05386719	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	N/A
Unknown	Effect of the App Bone@BC Version 4.0 Under the Follow-up for Patients With Early Breast Cancer NCT05280288	Rigshospitalet, Denmark	N/A
Recruiting	Adopting the MRD Strategy to Optimize Post-operation Adjuvant Therapies for Early Stage Breast Cancer NCT05345860	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	N/A
Recruiting	BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cance NCT04891068	University of Illinois at Chicago	Phase 2
Completed	A Randomized, Multicenter Pragmatic Trial Comparing Bone Pain From a Single Dose of Pegfilgrastim to 5 Doses o NCT04781959	Ottawa Hospital Research Institute	Phase 4
Active Not Recruiting	Hypofractionated Radiation Therapy vs Standard Treatment in Breast Cancer. NCT05318274	Coordinación de Investigación en Salud, Mexico	N/A
Recruiting	Targeted Axillary Dissection (TAD) in Early-stage Node Positive Breast Cancer NCT04671511	Jewish General Hospital	N/A
Recruiting	Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hor NCT04553770	Jonsson Comprehensive Cancer Center	Phase 2
Recruiting	Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Bre NCT04458532	Memorial Sloan Kettering Cancer Center	N/A
Recruiting	SABER Study for Selected Early Stage Breast Cancer NCT04360330	University of Miami	N/A
Completed	Axillary Staging in Early Breast Cancer: SNB vs PET/MRI NCT04829643	IRCCS San Raffaele	N/A
Completed	Evaluating Optimal Timing of Endocrine Therapy and Radiation Therapy in Early-stage Breast Cancer (REaCT-RETT) NCT03948568	Ottawa Hospital Research Institute	Phase 4
Completed	Extension Study to Provide Adjuvant Treatment Following Neoadjuvant Treatment and Surgical Resection in Protoc NCT04109391	Tanvex BioPharma USA, Inc.	Phase 3
Unknown	ABUS for Early-stage Breast Cancer NCT04607473	Samsung Medical Center	N/A
Unknown	Evaluating the Efficacy of Neratinib on Live Cell HER2 Signaling Transduction Analysis Positive Triple Negativ NCT03812393	West Cancer Center	Phase 2
Unknown	Deep Learning Algorithms for Prediction of Lymph Node Metastasis and Prognosis in Breast Cancer MRI Radiomics NCT04003558	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	—
Terminated	Improving Pre-operative Systemic Therapy for Human Epidermal Growth Factor Receptor 2 (HER2) Amplified Breast NCT03894007	Renske Altena	Phase 2
Completed	Adjuvant Partial-breast Irradiation Using Stereotactic Body Radiation Therapy NCT06007118	Masaryk Memorial Cancer Institute	N/A
Recruiting	COGNITION: Genomics-Guided Precision Oncology in Early High-Risk Breast Cancer NCT05906407	German Cancer Research Center	—
Active Not Recruiting	IORT-Breast at Medical Center Navicent Health NCT04595435	Wake Forest University Health Sciences	—
Active Not Recruiting	A Registry of Intra-Operative Radiation Therapy (IORT) Using the Xoft ® Axxent ® eBx ™ System Patients NCT03561454	MedStar Franklin Square Medical Center	—
Unknown	Prospective Cohort Study of Traditional Chinese Medicine for Survival of Patients With Early Breast Cancer NCT03797248	Chang Gung Memorial Hospital	—
Unknown	Intratumoral TriMix Injections in Early Breast Cancer Patients NCT03788083	Universitair Ziekenhuis Brussel	Phase 1
Completed	Comparing a Single-Dose vs. Twice Yearly Zoledronate in Patients With Early Stage Breast Cancer (REaCT-ZOL) NCT03664687	Ottawa Hospital Research Institute	Phase 4
Recruiting	Registry for Intra-Operative Radiotherapy During Breast Conserving Surgery in Patients With Early Stage Breast NCT04603209	Saint John's Cancer Institute	—
Completed	The ConnectedCancerCare Pilot Study (CCC) NCT03618017	University of Michigan Rogel Cancer Center	N/A
Unknown	Sentinel Lymph Node Identification in Patients With Breast Cancer Using SPECT/CT NCT03468374	Assiut University	N/A
Unknown	A Window of Opportunity Study of Pre-operative Endocrine Therapy With and Without Prometrium in Postmenopausal NCT03906669	St Vincent's Hospital	Phase 2
Completed	Comparing Tapering Low Dose Dexamethasone to Other Standard of Care Therapies for TAPS in Breast Cancer Patien NCT03348696	Ottawa Hospital Research Institute	Phase 4
Completed	Testing of the Cancer Thriving and Surviving Breast Cancer Program NCT03651921	Manuela Eicher	N/A
Completed	Registry Trial to Evaluate the Clinical Utilization of Targeted Axillary Dissection (TAD) NCT03102307	Kliniken Essen-Mitte	—
Unknown	Shandong Cancer Hospital Affiliated to Shandong University NCT02958033	Shandong Cancer Hospital and Institute	Phase 3
Completed	Granulocyte-colony Stimulating Factors or Antibiotics for Primary Prophylaxis for Febrile Neutropenia NCT02816112	Ottawa Hospital Research Institute	Phase 4
Completed	A Study to Compare Administration Schedules of G-CSF (Filgrastim) for Primary Prophylaxis of Febrile Neutropen NCT02816164	Ottawa Hospital Research Institute	Phase 4
Completed	Avoiding Growth Factor During Paclitaxel Treatment in Breast Cancer NCT02698891	Dana-Farber Cancer Institute	Phase 2
Active Not Recruiting	Phase I Dose Escalation of Single Fraction Adjuvant Stereotactic Body Partial Breast Irradiation Early Stage B NCT02685332	University of Texas Southwestern Medical Center	Phase 1
Completed	A Pragmatic Trial of Ambulatory Toxicity Management in Patients Receiving Adjuvant or Neo-adjuvant Chemotherap NCT02485678	Ontario Clinical Oncology Group (OCOG)	N/A
Unknown	Methylene Blue Intradermal Injection for Sentinel Lymph Node Biopsy for Breast Cancer Patients NCT02982148	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Phase 4
Completed	A Multi Centre Study to Determine the Feasibility of Using an Integrated Consent Model to Compare Standard of NCT02428114	Ottawa Hospital Research Institute	—
Completed	Evaluating Mass Spectrometry And Intraoperative MRI In The Advanced Multimodality Image Guided Operating Suite NCT02335671	Dana-Farber Cancer Institute	N/A
Active Not Recruiting	Partial Breast Irradiation Using Interstitial Permanent Palladium-103 Seed Implant NCT02297672	British Columbia Cancer Agency	N/A
Terminated	Targeted Intraoperative Therapy Registry at Bethesda North Hospital (TARGIT) NCT02364960	TriHealth Inc.	—
Completed	A Randomized, Controlled Trial to Determine the Effects of an Exercise Intervention on Physical Activity Durin NCT02159157	Dartmouth-Hitchcock Medical Center	N/A
Completed	Anti-proliferative Effects of Vitamin D and Melatonin in Breast Cancer NCT01965522	Juravinski Cancer Center	Phase 2
Completed	POWER-remote Weight Loss Program in Early Stage Breast Cancer NCT01871116	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	N/A
Terminated	Pilot Study to Evaluate the Impact of Denosumab on Disseminated Tumor Cells (DTC) in Patients With Early Stage NCT01545648	Hope Rugo, MD	Phase 2
Completed	Cyberknife® Partial Breast Irradiation (PBI) for Early Stage Breast Cancer NCT01162200	University of Texas Southwestern Medical Center	Phase 1
Completed	Cyberknife for Early Stage Breast Cancer NCT03946683	NYU Langone Health	N/A
Terminated	Impact of Breast Magnetic Resonance Imaging (MRI) on Mastectomy Rates NCT01166581	Summa Health System	—
Recruiting	I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer NCT01042379	QuantumLeap Healthcare Collaborative	Phase 2
Completed	Breast Cancer Diet Intervention Study NCT03886389	Helse Stavanger HF	N/A
Terminated	Trial to Evaluate Genomic Expression Profiles to Direct Preoperative Chemotherapy in Early Stage Breast Cancer NCT00636441	Duke University	Phase 2
Unknown	Survey of Optical Values of the Breast Using Radiation-Free Pressure-Free Optical Scanning NCT00671385	Spectros Corporation	—
Completed	Patient Centered Randomized Controlled Trial NCT00233077	Icahn School of Medicine at Mount Sinai	N/A
Completed	A Couples Approach to Enhance Breast Cancer Survivorship NCT00665899	University of North Carolina, Chapel Hill	N/A
Completed	Proton Therapy for Early Stage Breast Cancer NCT00614172	Loma Linda University	N/A
Completed	Tangential Radiation Therapy Without Axillary Dissection in Breast Cancer NCT00165243	Dana-Farber Cancer Institute	Phase 2
Completed	Pooled Analysis of Patients With Early-stage Breast Cancer Treated With Adjuvant Dose-dense Sequential Chemoth NCT07521397	Hellenic Cooperative Oncology Group	—
Completed	Randomized Study Comparing Pre- and Postoperative vs. Conventional Adjuvant Treatment in Receptor-negative Pat NCT00309569	Austrian Breast & Colorectal Cancer Study Group	Phase 3
Completed	Randomized Study Comparing CMF and Goserelin + Tamoxifen in Premenopausal Receptor-positive Patients NCT00309478	Austrian Breast & Colorectal Cancer Study Group	Phase 3
Completed	Randomized Study Comparing Tamoxifen vs. Tamoxifen + Aminoglutethimide in Postmenopausal Receptor-positive Pat NCT00309491	Austrian Breast & Colorectal Cancer Study Group	Phase 3