NCT00165243

Tangential Radiation Therapy Without Axillary Dissection in Breast Cancer

Tangential Radiation Therapy Without Axillary Dissection in Early-Stage Breast Cancer

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Dana-Farber Cancer Institute · Academic / Other
• Sex: All
• Age: 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate whether treatment to the axilla (area under the arm) can be safely minimized by omitting axillary surgery and full axillary radiation therapy and replacing it with radiation therapy to the breast and lower axilla.

Detailed description

* Patients will have undergone conservative breast surgery without axillary dissection prior to enrollment in this study. * Patients will receive radiation therapy to the breast, including the lowest axillary lymph nodes, over a period of 6 1/2 weeks. * No radiation will be specifically directed toward the upper axilla or supraclavicular lymph nodes. * Patients will also receive 5 years of tamoxifen or another type of hormone therapy determined by the medical oncologist. * Follow-up visits will occur every 6 months and mammograms every 12 months.

Conditions

• Early-Stage Breast Cancer

Interventions

Type	Name	Description
PROCEDURE	Tangential radiation	Radiation given over 6 1/2 weeks

Timeline

• Start date: 1998-09-01
• Primary completion: 2004-01-01
• Completion: 2016-12-01
• First posted: 2005-09-14
• Last updated: 2017-06-07

Locations

2 sites across 1 country: United States