Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT07483996

Cryoablation Versus Lumpectomy in Early-Stage Breast Cancer

Cryoablation as Alternative for Lumpectomy in Early-Stage Breast Cancer: The CRYSTAL Trial

Status
Not Yet Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
938 (estimated)
Sponsor
Franciscus Gasthuis & Vlietland (Hospital) · Academic / Other
Sex
Female
Age
60 Years
Healthy volunteers
Not accepted

Summary

The goal of this randomised controlled trial is to compare ipsilateral breast cancer recurrence rates in patients with early-stage breast cancer between patients treated with breast conserving surgery and patient treated with percutaneous cryo-ablation.

Conditions

Interventions

TypeNameDescription
PROCEDUREPercutaneous cryoablationIn this trial, the IceCure Prosense Cryoablation System will be used to execute the percutaneous cryoablation procedure.
PROCEDUREBreast-conserving surgeryBreast-conserving surgery

Timeline

Start date
2026-04-01
Primary completion
2035-12-31
Completion
2038-12-31
First posted
2026-03-19
Last updated
2026-03-19

Source: ClinicalTrials.gov record NCT07483996. Inclusion in this directory is not an endorsement.