Clinical Trials Directory

Trials / Sponsors / National Cancer Centre, Singapore

National Cancer Centre, Singapore

Academic / Other · 111 registered clinical trials30 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingSacituzumab Tirumotecan in Recurrent/Metastatic Adenoid Cystic Carcinoma and Papillary Thyroid Carcinoma (STRA
Recurrent Adenoid Cystic Carcinoma, Adenoid Cystic Carcinoma Metastatic, Papillary Thyroid Carcinoma
Phase 22026-05-01
Not Yet RecruitingRestoring Bile Acid Homeostasis Via Lifestyle Adjustments to Prevent the Development of Liver Cancer
Liver Diseases
N/A2026-01-01
RecruitingHistotripsy for Ablation of Liver Tumours in Asia
Liver Malignant Tumors
N/A2025-11-07
Not Yet RecruitingSensory Enrichment Using Aromatherapy for Neurobehavioral and Psychological Symptoms in Early Dementia
Mild Cognitive Impairment, Mild Dementia
N/A2025-11-01
Active Not RecruitingAcceptability and Feasibility of PSC Model of Serious Illness Communication
Advanced Breast Cancer
N/A2025-08-25
RecruitingExercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore
Fatigue, Breast Cancer Female
N/A2025-07-14
RecruitingFeasibility, Acceptability and Preliminary Efficacy of the New Iteration of the Innovative Smartphone-based Ca
Breast Cancer
N/A2025-05-23
RecruitingIntramuscular ACM-CpG Monotherapy in Patients With Advanced/Metastatic Solid Tumors With Prior Response to Imm
Advanced Solid Tumor, Metastatic Solid Tumor
Phase 12025-01-15
RecruitingEvaluating the Effectiveness of Aromatherapy for Alleviating Distress in Breast Cancer Patients Before Radioth
Breast Cancer
N/A2024-10-22
RecruitingInnovating Access to Novel Therapies Through Standardized Prospective Integration of Response Evaluations (IMP
Solid Tumor
2024-09-12
RecruitingTimely Interventions to Enable and Reach Patients With Heart Failure, and Their Caregivers With Palliative Car
Heart Failure
N/A2024-08-14
RecruitingTislelizumab and Metronomic Capecitabine as Maintenance in High-risk Locoregionally-advanced Nasopharyngeal Ca
Nasopharyngeal Carcinoma
Phase 22024-07-03
RecruitingPembrolizumab and Olaparib Treatment for Relapsed or Refractory Peripheral T-Cell Lymphoma
Relapsed Peripheral T-Cell Lymphoma, Refractory Peripheral T-Cell Lymphoma
Phase 22024-07-01
RecruitingA Pan-Asian Clinical Database of EGFR Exon 20 Insertion Mutated NSCLC
Advanced EGFR Exon 20 Insertion Mutated Non-Small Cell Lung Cancer
2024-03-15
RecruitingEvaluation and Implementation Preparation of a Proactive Palliative Care Model (ENABLE-SG)
Neoplasms
N/A2023-12-26
RecruitingMetronomic Capecitabine, Oxaliplatin and UGT1A1 Genotype-directed Irinotecan in Metastatic Pancreatic Cancer P
Metastatic Pancreatic Cancer
Phase 22023-08-30
Active Not RecruitingA Phase 2 Study of Osimertinib and S-1 in Treatment Resistant EGFR Mutant NSCLC
NSCLC
Phase 22023-08-01
RecruitingBreast Cancer Exercise Intervention Study
Early-stage Breast Cancer, Locally Advanced Breast Cancer
N/A2023-07-01
UnknownPhase II 177Lu-DOTATATE Study in Metastatic NPC With a Safety Run-in
Metastatic Nasopharyngeal Cancer
Phase 22023-05-05
RecruitingDeep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bev
Hepatocellular Carcinoma
Phase 22023-02-28
RecruitingPhase II Lenvatinib and Pembrolizumab in Endocrine Resistant Breast Cancer With Letrozole
Hormone Receptor-Positive HER2-Negative Advanced Breast Cancer
Phase 22023-02-15
CompletedImpacts of Durian Consumption on Human Microbiome and Metabolome in Healthy Staff Volunteers
Diet, Food and Nutrition
N/A2023-02-01
RecruitingtReatment Individualisation By EBV stratificatiON in Nasopharyngeal Carcinoma: an Umbrella Platform Study (RIB
Nasopharyngeal Carcinoma
2022-11-17
RecruitingMultinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atez
Locally Advanced Hepatocellular Carcinoma
Phase 22022-10-26
RecruitingSingapOre Lung Cancer Screening Through Integrating CT With Other biomarkErs (SOLSTICE)
Lung Cancer
N/A2022-07-21
CompletedENABLE (Educate, Nurture, Advise, Before Life Ends) Intervention for Heart Failure (HF) Patients and Their Car
Heart Failure
N/A2022-02-14
CompletedPSMA-PET Imaging of Salivary Gland Tumours and Other Rare Cancers
Salivary Gland Tumor, Rare Malignant Neoplasm
2022-01-26
Active Not RecruitingProspective Cohort Study of Changes in Circulatory MicroRNA of Resected Hepatocellular Carcinoma
Hepatocellular Carcinoma
2021-11-10
Active Not RecruitingPhase-2 Dacomitinib Study on Patients With EGFR-Driven Advanced Solid Tumours With Low EGFR-AS1 IncRNA Expr or
Advanced Solid Tumours, Non-small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma
Phase 22021-08-24
RecruitingPIPAC for Peritoneal Metastases
Peritoneal Metastases
Phase 12021-05-20
RecruitingNeoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC
Hepatocellular Carcinoma, Hepatocellular Cancer, Colorectal Cancer
Phase 22021-04-15
Active Not RecruitingEarly Detection of Hepatocellular Carcinoma in a High-risk Prospective Cohort (ELEGANCE)
Liver Diseases
2021-04-15
CompletedImpact of a Breast cAncer Survivorship Interprofessional Community Care Model
Survivorship, Breast Cancer
N/A2021-03-01
CompletedNovel Palliative Care Model for Advanced Cancer Patients: A Randomized Controlled Trial Study
Cancer
N/A2021-02-08
RecruitingTelegenetics or In-Person Genetic Counselling
Genetic Counselling
2021-02-01
UnknownDose-determining and Dose-confirmatory Study to Investigate the Optimal Dose of Tamoxifen in Breast Cancer Pat
Breast Cancer
Phase 12020-12-23
UnknownClinical Trial of Chemotherapy, Oregovomab and Nivolumab in Patients With Epithelial Cancer of Ovarian, Tubal
Epithelial Ovarian Cancer
Phase 1 / Phase 22020-10-07
CompletedThe Role of Bexarotene in Inducing Susceptibility to Chemotherapy in Metastatic TNBC
Metastatic Triple-Negative Breast Carcinoma
Phase 12020-10-01
RecruitingUsing QPOP to Predict Treatment for Sarcomas and Melanomas
Sarcoma, Melanoma
2020-09-08
CompletedImpact of Measures Taken to Contain COVID-19 on Hospital Surgical Care Services and Clinical Outcomes
Surgery
2020-08-01
CompletedSomatostatin Receptor Imaging in NPC, EBV Related Cancers
Nasopharyngeal Cancer, Epstein-Barr Virus Related Carcinoma
N/A2020-06-29
CompletedPhase 2 Trial in Multiple Brain Metastases Outcomes With HA-SIB-WBRT
Brain Metastases
Phase 22020-06-15
WithdrawnNivolumab in Combination With GDP/ L-asparaginase in NK/ T-cell Lymphoma
NK/T Cell Lymphoma
Phase 12019-12-12
UnknownLongitudinal Immune-phenotyping of HCC Following MK-3475
Hepatocellular Carcinoma
Phase 12019-12-10
Active Not RecruitingPhase 2 Study of Dacomitinib in NSCLC
NSCLC Stage IIIB, NSCLC Stage IIIC, NSCLC Stage IV
Phase 22019-09-11
RecruitingPhase II Study of PRL3-ZUMAB in Advanced Solid Tumors
Gastric Cancer, Hepatocellular Carcinoma, Advanced Solid Tumor
Phase 22019-09-03
RecruitingPlasma Molecular Profiling in ALK Inhibitor Resistant NSCLC
Non-small Cell Lung Cancer, ALK-Positive Lung Cancer
2019-08-23
CompletedWindow of Opportunity Study in Colorectal Cancer
Colorectal Cancer
Phase 22019-06-12
UnknownA Novel Functional Imaging Technique With FLT-PET/MRI For Staging, Response Assessment and Radiation Treatment
Image, Body, Cervix Cancer
N/A2019-05-14
RecruitingMolecular Profiling Project
Lung Cancer, Non-Small Cell Lung Cancer
2019-01-11
TerminatedAfatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC
Non-small Cell Lung Cancer, Leptomeningeal Disease, Central Nervous System Metastases
Phase 12018-11-16
CompletedLiverMultiScan Analysis of MRI Scans in HCC
Hepatocellular Carcinoma
2018-10-19
UnknownStudy of Trametinib and Ruxolitinib in Colorectal Cancer and Pancreatic Adenocarcinoma
Colorectal Cancer, Pancreatic Adenocarcinoma
Phase 12018-07-31
UnknownRadical Resection and HIPEC for Recurrent Retroperitoneal Sarcoma
Retroperitoneal Sarcoma
N/A2018-07-23
CompletedTrial Comparing Active Intervention At Diagnosis With Usual Care to Improve Psycho-social Care in AYAO
Carcinoma, Lymphoma, Sarcoma
N/A2018-04-16
CompletedEffectiveness of the Supportive and Palliative Care Review Kit (SPARK) for Cancer Patients in the Acute Hospit
Health Services Research
N/A2017-12-01
CompletedProphylactic HIPEC for Colorectal Cancers at High Risk of Developing Peritoneal Metastases
Colorectal Cancer, Peritoneal Metastases
N/A2017-09-28
CompletedPredicting Survival After Surgical Resection for the Entire Spectrum of Anatomically Resectable HCC
Hepatocellular Carcinoma Resectable
2017-07-17
Completed18F-FMISO PET Guided Dose Escalation in Nasopharyngeal Carcinoma - a Feasibility and Planning Study
Nasopharyngeal Carcinoma
N/A2017-06-20
CompletedPerioperative Immunonutrition for Patients Undergoing CRS and HIPEC
Peritoneal Metastases
N/A2017-04-23
CompletedHepatocellular Carcinoma Registry in Asia: The INSIGHT Registry
Hepatocellular Carcinoma
2017-04-17
TerminatedStudy of Nivolumab Verses Nivolumab and Ipilimumab Combination in EGFR Mutant Non-small Cell Lung Cancer
Non-Small Cell Lung Cancer
Phase 22017-04-07
UnknownPhase 2 Trial of Ipilimumab and Nivolumab in Nasopharyngeal Carcinoma
Nasopharyngeal Carcinoma
Phase 22017-03-31
TerminatedPhase Ib/IIa Trial to Evaluate Oregovomab and Nivolumab in Epithelial Cancer of Ovarian, Tubal or Peritoneal O
Epithelial Ovarian Cancer
Phase 1 / Phase 22017-02-22
Active Not RecruitingStudy of Y90-Radioembolization With Nivolumab in Asians With Hepatocellular Carcinoma
HepatoCellular Carcinoma
Phase 22016-12-20
UnknownRegional Cryotherapy in Preventing Paclitaxel Induced Peripheral Neuropathy in Breast Cancer Patients
Breast Cancer
Phase 22016-09-01
TerminatedPhase II Study to Assess the Efficacy of ASLAN001 Plus Capecitabine in CNS Metastases for HER2+ Breast Cancer
HER2-positive Breast Cancer
Phase 22016-08-11
CompletedEnhancing Quality of Life in Patients (EQUIP) Intervention for Patients With Advanced Lung Cancer
Advanced Lung Cancer
N/A2016-08-01
TerminatedPhase II Study of Ibrutinib in Patients With Relapsed or Refractory Marginal Zone Lymphoma
Lymphoma, B-Cell, Marginal Zone
Phase 22016-07-08
CompletedPhase I Trial of Selinexor (KPT-330) and Ifosfamide, Carboplatin, Etoposide (ICE) in Peripheral T-cell Lymphom
Peripheral T-cell Lymphoma
Phase 12016-07-01
CompletedProspective Cohort Study on the Clinical Trajectory of Resected Hepatocellular Carcinoma
Hepatocellular Carcinoma
2016-05-16
CompletedUse of Regorafenib in Recurrent Epithelial Ovarian Cancer
Ovarian Neoplasms
Phase 22016-02-03
CompletedPilot Study of the SPaRK (Supportive and Palliative Care Review Kit) Model of Care for Advanced Cancer Patient
Cancer
N/A2015-11-22
RecruitingDiscovery of Biomarkers for Intrinsic Radiation Sensitivity in Cancer Patients
Nasopharyngeal Cancer, Prostate Cancer, Other Cancer
2015-09-30
CompletedPilot Study of Somatostatin Receptor Imaging in Nasopharyngeal Cancer
Nasopharyngeal Carcinoma
2015-08-20
UnknownUse of Non-invasive 4D Ultrasound Clarity System in Prostate IMRT/RapidArc Therapy
Prostate Cancer
2015-04-01
CompletedPRe-Operative Gefitinib in Resectable EGFR Mutation Positive Lung Cancer With Sector Sequencing for Biomarker
Non-small Cell Lung Cancer
Phase 22015-01-27
UnknownASLAN001 in Combination With Oxaliplatin and Capecitabine or Oxaliplatin and 5-FU With Leucovorin
Solid Tumors
Phase 12014-08-01
CompletedOXIRI [Oxaliplatin (O), Xeloda (X) and Irinotecan (I)] in Pancreatic Adenocarcinoma
Pancreatic Cancer
Phase 12013-09-17
UnknownStereotactic Body Radiotherapy for Organ Confined Prostate Cancer
Prostate Cancer
Phase 22013-06-01
TerminatedA Study Into the Effect of Seprafilm in Open Total Thyroidectomy
Thyroid Carcinoma
N/A2013-05-01
CompletedComparing Harmonic Ultrasonic Scalpel to Small Jaw Bipolar Device in Thyroid Surgery
Thyroid Diseases
N/A2012-12-01
CompletedClinical Study of Metronomic Oral Cyclophosphamide in Patients With Advanced Sarcomas
Sarcoma
Phase 22012-06-01
CompletedA Trial of Gefitinib in Combination With BKM120 in Patients With Advanced Non-Small Cell Lung Cancer, With Enr
Non-Small Cell Lung Cancer, Solid Tumors
Phase 12011-10-03
RecruitingIndividualized Molecular Profiling for Allocation to Clinical Trials (IMPACT) Project
Solid Tumor
2011-10-01
TerminatedStudy of TKI 258 in Combination With Xeloda and Oxaliplatin in Advanced Colorectal and Gastric Cancer
Colorectal Cancer, Gastric Cancer
Phase 12011-09-01
TerminatedDiffuse Optical Tomography (DOT) for Monitoring Response to Neoadjuvant (Preoperative) Chemotherapy in Breast
Breast Neoplasms
2011-08-01
CompletedStudy of Ofatumomab in Combination With ICE-chemotherapy in Patients With Diffuse Large B-cell Lymphoma (DLBCL
Diffuse Large B-cell Lymphoma
Phase 22011-04-01
TerminatedBortezomib With Combination of Gemcitabine, Ifosfamide and Oxaliplatin in Untreated NK/T Cell Lymphoma
Extranodal NK-T-CELL LYMPHOMA
Phase 22011-03-01
CompletedStudy of Neoadjuvant Docetaxel and Cyclophosphamide in Locally Advanced or Node Positive Primary Breast Cancer
Breast Cancer
Phase 22010-08-11
CompletedA Phase 2 Study of Trastuzumab in Combination With TS-ONE and Cisplatin in Firstline Human Epidermal Growth Fa
HER 2 Positive Advanced Gastric Cancer
Phase 22010-05-01
UnknownSafety and Tolerability Study of RAD001 and LBH589 in All Solid Tumors With Enrichment for EBV Driven Tumors
Nasopharyngeal Carcinoma, Lymphomas, Any EBV+ Solid Tumour
Phase 12010-03-01
TerminatedAZD6244 and Sorafenib in Advanced Hepatocellular Carcinoma
Hepatocellular Carcinoma
Phase 1 / Phase 22009-11-01
UnknownClinical Validation of a Microfluidic Device for Isolation and Molecular Characterization of Circulating Tumor
Cancer
2009-10-01
UnknownCisplatin and RT With or Without Gemcitabine, Carboplatin, and Paclitaxel in Treating Patients With Locally Ad
Head and Neck Cancer
Phase 2 / Phase 32009-09-15
UnknownStudy of Post-Op Adjuvant Concurrent Chemo-RT With or Without Nimotuzumab for Head & Neck Cancer
Carcinoma, Squamous Cell of Head and Neck
Phase 32009-08-13
UnknownAspirin for Dukes C and High Risk Dukes B Colorectal Cancers
Colorectal Cancer
Phase 32008-12-01
UnknownCyclophosphamide and Docetaxel or Doxorubicin in Treating Women With Newly Diagnosed Breast Cancer That Can Be
Breast Cancer
Phase 22008-10-01
UnknownGemcitabine and Carboplatin Followed By Laboratory-Treated T Lymphocytes in Treating Patients With Metastatic
Head and Neck Cancer
Phase 22008-07-01
CompletedStudy of Combination of Metronomic Oral Vinorelbine and Sorafenib in Patients With Advanced Non-small Cell Lun
Non-Small Cell Lung Cancer
Phase 12008-06-01
UnknownCyclophosphamide, Methotrexate, and Prednisolone With or Without Aromatase Inhibitor Therapy in Treating Postm
Breast Cancer
Phase 22008-05-01
CompletedStudy of Nimotuzumab and Cisplatin/Radiotherapy for Locally Advanced Head and Neck Squamous Cell Cancer
Head and Neck Cancer
Phase 22008-04-28
CompletedIrinotecan in Treating Asian Patients With Solid Tumors
Unspecified Adult Solid Tumor, Protocol Specific
Phase 12008-04-03
CompletedStudy of Oral Vinorelbine and Erlotinib in Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer
Phase 12008-04-01
TerminatedPaclitaxel, Doxorubicin, and Cyclophosphamide With Or Without Carboplatin in Treating Women With Locally Advan
Breast Cancer
Phase 22008-01-01
UnknownVaccine Therapy and Celecoxib in Treating Patients With Metastatic Nasopharyngeal Cancer
Head and Neck Cancer
Phase 22007-11-01
TerminatedPyridoxine in Preventing Hand-Foot Syndrome Caused by Capecitabine in Patients With Cancer
Dermatologic Complications, Palmar-plantar Erythrodysesthesia, Unspecified Adult Solid Tumor, Protocol Specific
Phase 32007-06-01
UnknownCombination Chemotherapy and Interferon Alfa-2b in Treating Patients With Nonmetastatic Liver Cancer That Cann
Liver Cancer
Phase 22007-03-01
CompletedSirolimus and Bevacizumab in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
Liver Cancer
Phase 12006-12-01
UnknownRadiation Therapy Alone Compared to Radiation Therapy Plus Chemotherapy in Treating Patients With Previously U
Head and Neck Cancer
Phase 31998-09-01
CompletedSurgery and Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Stage
Head and Neck Cancer
Phase 31997-01-01