NCT04340024

Discovery of Biomarkers for Intrinsic Radiation Sensitivity in Cancer Patients

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 5,000 (estimated)
• Sponsor: National Cancer Centre, Singapore · Academic / Other
• Sex: All
• Age: 21 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

Patients with cancers that are sensitive to radiotherapy treatment and/or patients who have experienced severe acute/ late side effects to radiotherapy will be recruited to the study. Blood and/or matched tumour-normal tissue pairs will be collected. Blood and/or tissue samples will be processed and studied for genetic and biochemical markers that have potential to be used for predicting sensitivity to radiation.

Conditions

• Nasopharyngeal Cancer
• Prostate Cancer
• Other Cancer

Timeline

• Start date: 2015-09-30
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2020-04-09
• Last updated: 2025-06-11

Locations

1 site across 1 country: Singapore