NCT03946683

Cyberknife for Early Stage Breast Cancer

Cyberknife Radiosurgery for Early Stage Breast Cancer: A Winthrop-University Hospital Pilot Study of Cyberknife Partial Breast Radiosurgery for Tumors 3 cm or Less

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 26 (actual)
• Sponsor: NYU Langone Health · Academic / Other
• Sex: Female
• Age: 45 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

This phase II study based on the Cyberknife Society study will evaluate the technical feasibility and acute toxicity of Partial Breast Irradiation (PBI) with the Cyberknife. It will evaluate quality of life (QOL) issues as they relate to treatment-related side effects, cosmetic result and patient convenience. It will evaluate outcome in terms of local control in the treated breast. Radiosurgery is defined as the stereotactic delivery of ionizing radiation in 5 stages or less to a designated target with sub-millimeter accuracy. Radiosurgery in the context of this protocol will be given to the region of the tumor bed with 7 weeks of the lumpectomy and sent/axillary node sampling over the period of five to ten days using the Cyberknife (CK) or within the 7 weeks of the last chemotherapy treatment if given.

Conditions

• Early Stage Breast Cancer

Interventions

Type	Name	Description
RADIATION	Cyberknife for Early Stage Breast Cancer	Utilization of Cyberknife Robotic Radiosurgery as a 5-fraction post-lumpectomy adjuvant radiation treatment in the management of early stage breast cancer

Timeline

• Start date: 2010-09-01
• Primary completion: 2014-09-30
• Completion: 2020-04-23
• First posted: 2019-05-13
• Last updated: 2021-02-18

Locations

1 site across 1 country: United States