| Recruiting | Plantar Pressure and Acceptance of the LEEF-shoe in Individuals With Diabetes-related Neuropathy NCT07488104 | University Medical Center Groningen | N/A |
| Not Yet Recruiting | Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients NCT07404124 | Fatih Sultan Mehmet Training and Research Hospital | N/A |
| Enrolling By Invitation | Efficacy and Feasibility of BurstDR SCS in Painful Diabetic Neuropathy NCT07250828 | TriCity Research Center | N/A |
| Not Yet Recruiting | Vitamin D, Nerve Growth Factor and Nerve Conduction Studies in Adult Male Type 2 Diabetic Neuropathy Patients NCT07236723 | Aswan University | — |
| Recruiting | Effects of Turning Based Dual Task Training on Balance and Mild Cognitive Impairment in Diabetic Peripheral Ne NCT07394504 | Foundation University Islamabad | N/A |
| Active Not Recruiting | Effect of Golden Rice-Piper Crocatum Cookies on Neuropathy Prevention in Diabetes NCT07272993 | Hasanuddin University | N/A |
| Not Yet Recruiting | GlucoBites Cookies (Gynura Procumbens) for Glycemic Control and Prevention of Diabetic Foot Ulcer Risk in Type NCT07151833 | Andina Setyawati | N/A |
| Completed | Additional Effects of Sensory Integration Along With Focused Regimen Exercises on Kinaesthesia & Proprioceptio NCT07332364 | Foundation University Islamabad | N/A |
| Completed | CGM-Guided Acarbose for Painful Diabetic Neuropathy NCT07436585 | Shifa International Hospital | Phase 1 |
| Recruiting | Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy NCT07036796 | Ain Shams University | Phase 2 |
| Enrolling By Invitation | Comparison of Active vs Passive Neural Mobilizations Effects in Improving Burning Pain, Muscular Strength, and NCT07141992 | Dow University of Health Sciences | N/A |
| Recruiting | The Relation Between Diabetic Neuropathy and Muscle Mass in Type 2 Diabetes Mellitus Patients NCT06958302 | Ain Shams University | — |
| Recruiting | Effect of Reiki on Neuropathic Pain Severity and Sleep Quality in Patients With Diabetic Neuropathy NCT06668623 | TC Erciyes University | N/A |
| Recruiting | Additional Effects of Neural Mobilization on Pain, Balance and Quality of Life in Diabetic Neuropathy NCT07210203 | Foundation University Islamabad | N/A |
| Recruiting | Clinical Outcomes Related to Treatment of Distal Symmetric Polyneuropathy Using Semiconductor Embedded Therape NCT06452914 | Endocrine Research Solutions | N/A |
| Active Not Recruiting | Long COVID-19 Cutaneous Signatures: An ARPA Funded Research Project NCT07005947 | CND Life Sciences | — |
| Completed | Basket Study (CT-100-002) to Evaluate the Effects of a DiNaMo™ Component Training NCT05573685 | Click Therapeutics, Inc. | N/A |
| Completed | High Diagnostic Performance of the Indicator Plaster Neuropad for the Detection of Diabetic Autonomic Neuropat NCT06734143 | Aristotle University Of Thessaloniki | — |
| Completed | Skin Stretch Sensory Stimuli and TENS in Diabetic Neuropathy NCT05250999 | Riphah International University | N/A |
| Completed | Effects of Proprioceptive Training in Addition to Routine Physical Therapy on Balance and Quality of Life in P NCT05243589 | Momna Asghar | N/A |
| Completed | FDGL Dose-Finding Study for Diabetic Neuropathy NCT07117942 | Helwan University | Phase 2 |
| Completed | Gremlin-1 and Wagner Classification: Potential Biomarker for Amputation in Diabetic Foot Patients NCT06753604 | Seyma Acik | — |
| Completed | The Effect of Intraneural Facilitation Therapy on Diabetic Patients With Peripheral Neuropathy NCT04025320 | Loma Linda University | N/A |
| Terminated | Phase 2a Study Examining the Safety and Efficacy of BOL-DP-o-04 for Treating Diabetic Neuropathy NCT04082000 | Breath of Life International Pharma Ltd | Phase 1 / Phase 2 |
| Completed | ACUpuncture in Diabetic Peripheral Neuropathy NCT03755960 | Benno Brinkhaus | N/A |
| Completed | The Efficacy and Safety Profile of Capsaicin 8% Patch Versus 5% Lidocaine Patch in Males With Diabetic Neuropa NCT04238208 | Corporacion Parc Tauli | Phase 4 |
| Completed | Understanding Risk Factors and Determinants for Neuropathic Pain NCT02402361 | Rambam Health Care Campus | — |
| Completed | Efficacy of γ-linolenic Acid and Thioctic Acid in Patients With Diabetic Neuropathy NCT03914404 | Chonbuk National University Hospital | Phase 4 |
| Completed | The Efficacy and Safety of Clonidine Hydrochloride Topical Gel, vs Clonidine Hydrochloride Gel Comparator to T NCT02643251 | BioDelivery Sciences International | Phase 2 |
| Unknown | Activity for Diabetic Polyneuropathy NCT02341261 | Virginia Commonwealth University | N/A |
| Unknown | The Balance Control Mechanism of DPN Patients NCT02606747 | Geheng Yuan | — |
| Completed | PRELIMINARY EVALUATION OF PHARMACOLOGICAL LOWERING OF AGEs NCT02249897 | University of Chile | Phase 4 |
| Withdrawn | Differential Characteristics of Neuropathy in Type 2 Diabetics With and Without Lower Extremity Wounds NCT02347709 | Winthrop University Hospital | — |
| Completed | Evaluation of Rocker sOles in Diabetis NCT02891928 | University Hospital, Brest | Phase 4 |
| Completed | Less Neuropathy After Yoga- Managing Diabetic Neuropathy With Yoga NCT02659007 | Colorado State University | Phase 1 |
| Completed | A Study of Phyllanthus Niruri and Sida Cordifolia in Diabetic Peripheral Polyneuropathy NCT02107469 | Rosenberg European Academy of Ayurveda | N/A |
| Withdrawn | The Peripheral Mobilized Mononuclear Cell-based Therapy in Patient With Diabetic Neuropathy NCT02315235 | Seoul National University Hospital | N/A |
| Completed | The Effect of Random Vibrations on Perception and Balance NCT02989831 | University Medical Center Groningen | N/A |
| Completed | Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Pain Associated With Diabetic Neuropath NCT02068027 | BioDelivery Sciences International | Phase 2 |
| Completed | Characteristics of Popliteal Sciatic Nerve Block in Patients With and Without Diabetic Neuropathy NCT02076945 | Centre Hospitalier Universitaire Vaudois | N/A |
| Completed | Study of DA-9801 to Treat Diabetic Neuropathy NCT01822925 | NeuroBo Pharmaceuticals Inc. | Phase 2 |
| Completed | A Nutritional Intervention for Diabetic Neuropathy (WCCR-DN2) NCT01953757 | Physicians Committee for Responsible Medicine | N/A |
| Unknown | Effects of a Homeopathic Anti-inflammatory Topical Cream on Ulcers and Neuropathy in the Diabetic Foot NCT01951859 | Calvary Hospital, Bronx, NY | N/A |
| Unknown | Efficacy and Safety of KW21052 Compared to Lyrica in the Diabetic Patients With Neuropathic Pain NCT01863810 | KunWha Pharmaceutical Co., Ltd. | Phase 3 |
| Completed | A Nutritional Intervention for Diabetic Neuropathy NCT01690962 | Physicians Committee for Responsible Medicine | N/A |
| Completed | NIR- and Multifrequent Impedance Spectroscopy on the Skin in Type 1 Diabetes NCT01707979 | Lise Tarnow | — |
| Completed | Pilot Study of Exercise and Peripheral Nerve Function in People With Diabetes - ENRGy2 Addendum NCT01764373 | University of Kansas | N/A |
| Completed | Vitamin D Treatment for Painful Diabetic Neuropathy NCT02737423 | Baqai Institute of Diabetology and Endocrinology | N/A |
| Terminated | Time To Complications Occurs in Diabetes NCT00969956 | Karolinska Institutet | — |
| Unknown | A Clinical Outcomes Study to Measure Reduction in Pain and Numbness During Administration of an Amino Acid For NCT01537705 | Targeted Medical Pharma | Phase 2 |
| Completed | Can Ultrasound Predict Nerve Injury Following Posterior Tibial Nerve Block in Patients With Peripheral Neuropa NCT01002053 | University Health Network, Toronto | — |
| Completed | Efficacy Of CACIPLIQ20 On Diabetic Ulcers In Patients Wearing An Nonremovable, Windowed, Fiberglass Cast Boot NCT01474473 | Organ, Tissue, Regeneration, Repair and Replacement | N/A |
| Completed | Neuroprotection by Tocotrienols in Type 1 and Type 2 Diabetes Mellitus NCT01973400 | Universiti Sains Malaysia | Phase 3 |
| Completed | Complementary and Integrative Therapy for Diabetic Neuropathy NCT01296308 | Universität Duisburg-Essen | — |
| Unknown | Pain In Neuropathy Study NCT02672059 | King's College London | — |
| Completed | A Study to Evaluate the Safety of DA-3030 and to Explore the Efficacy for Diabetic Neuropathic Pain NCT01820715 | Dong-A Pharmaceutical Co., Ltd. | Phase 1 |
| Completed | Exercise-facilitated Neurorehabilitation in Diabetic Neuropathy NCT00955201 | VA Office of Research and Development | N/A |
| Completed | Alpha Lipoic Acid for Treatment of Diabetic Neuropathy NCT02439879 | Universidad Popular Autónoma del Estado de Puebla | Phase 4 |
| Terminated | A Study of Effectiveness and Safety of JNJ-42160443 in Patients With Diabetic Painful Neuropathy NCT00993018 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 2 |
| Completed | Lovaza® and Microvascular Function in Type 2 Diabetes NCT00931879 | Eastern Virginia Medical School | Phase 4 |
| Completed | Role of Indicator Test (Neuropad) in Detecting Diabetic Neuropathy NCT00895440 | Tameside Hospital NHS Foundation Trust | — |
| Completed | Study to Evaluate the Analgesic Efficacy of 28 Days' Oral Administration of AZD2066 Compared With Placebo in P NCT00857623 | AstraZeneca | Phase 2 |
| Unknown | The Evaluation of Safety and Efficacy of JWHGWT on Diabetic Neuropathy NCT00886665 | Taichung Veterans General Hospital | Phase 3 |
| Completed | Exercise and Nerve Function in Diabetes NCT00970060 | Patricia Kluding, PhD | N/A |
| Unknown | Diabetic Neuropathy Topical Treatment NCT00661063 | Irmandade da Santa Casa de Misericordia de Sao Paulo | Phase 3 |
| Completed | Neuropathic Pain Syndrome Patient Study (MK-0000-072) NCT00570310 | Merck Sharp & Dohme LLC | Phase 1 |
| Completed | Centella Asiatica Selected Triterpenes (CAST) for Diabetic Neuropathy NCT00608439 | Oregon Health and Science University | Phase 2 |
| Unknown | Determining Rates of Cardiovascular Complications Among Patients of a Managed Diabetes Care Program NCT00498147 | Group Health Centre | — |
| Completed | An Evaluation of the Efficacy and Safety of E2007 in Patients With Painful Diabetic Neuropathy NCT00505284 | Eisai Inc. | Phase 2 / Phase 3 |
| Completed | Efficacy Study With 500 mg QD of TRO19622 vs Placebo in Patients With Painful Peripheral Diabetic Neuropathy NCT00496457 | Hoffmann-La Roche | Phase 2 |
| Completed | A Safety and Efficacy Study for Tapentadol (CG5503) Extended Release for Patients With Painful Diabetic Periph NCT00455520 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 3 |
| Terminated | Effect of Holofiber Socks and Bedding on Pain and Quality of Sleep in Subjects With Chronic Foot Pain NCT00458497 | Southern California Institute for Research and Education | N/A |
| Terminated | Spinal Cord Stimulation for Painful Diabetic Neuropathy NCT00487981 | Boston Scientific Corporation | Phase 4 |
| Completed | A Study to Compare Safety and Efficacy of Tramadol Hydrochloride/Acetaminophen With Gabapentin in Participants NCT00634543 | Janssen Korea, Ltd., Korea | Phase 4 |
| Completed | Safety and Efficacy Study of QR-333 in Patient's With Symptomatic Diabetic Neuropathy NCT00568035 | Quigley Pharma, Inc. | Phase 2 |
| Completed | Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of AV411 in Neuropathic Pain NCT00576277 | Avigen | Phase 1 / Phase 2 |
| Completed | A Randomized Double-Blind Study Testing the Effects of Pregabalin on Diabetic Neuropathy NCT00573261 | Duke University | Phase 4 |
| Completed | Hematopoietic Stem Cell Transplantation for the Treatment of Limb Ischemia and Diabetic Neuropathy NCT00730561 | Hospital Universitario Dr. Jose E. Gonzalez | N/A |
| Completed | Safety and Efficacy of Dextromethorphan and Quinidine in the Treatment of the Pain of Diabetic Neuropathy NCT00113620 | Avanir Pharmaceuticals | Phase 3 |
| Completed | A Study of Sativex® for Pain Relief Due to Diabetic Neuropathy NCT00710424 | Jazz Pharmaceuticals | Phase 3 |
| Completed | Anodyne Therapy in Diabetic Sensory Neuropathy NCT00120341 | Scott and White Hospital & Clinic | Phase 4 |
| Completed | Clinical Trial of SB-509-0401 in Subjects With Diabetic Neuropathy NCT00110500 | Sangamo Therapeutics | Phase 1 |
| Withdrawn | Effects of Pulsatile Intravenous Insulin Delivery on Diabetic Neuropathy in pATIENTS (Pts) With Type 1 and Typ NCT00228904 | Florida Atlantic University | Phase 2 / Phase 3 |
| Completed | Safety and Efficacy of AS-3201 in the Treatment of Diabetic Sensorimotor Polyneuropathy NCT00101426 | Sumitomo Pharma Co., Ltd. | Phase 3 |
| Completed | The Effect of Ruboxistaurin on Small Fiber Function NCT00190970 | Chromaderm, Inc. | Phase 2 |
| Completed | Cognitive Behavioral Therapy for Painful Diabetic Neuropathy NCT00830011 | VA Connecticut Healthcare System | N/A |
| Completed | A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic Neuropathy NCT00235443 | UCB Pharma | Phase 2 / Phase 3 |
| Completed | An Open Label, Dose Finding Trial of Viagra for the Treatment of Neuropathic Pain (in Diabetes Mellitus) NCT00194909 | Weill Medical College of Cornell University | Phase 4 |
| Completed | A Trial to Assess the Efficacy and Safety of SPM 927 in Subjects With Painful Distal Diabetic Neuropathy NCT00235469 | UCB Pharma | Phase 2 / Phase 3 |
| Completed | A Trial to Assess the Efficacy and Safety of SPM 927 (Lacosamide) in Subjects With Painful Distal Diabetic Neu NCT00238524 | UCB Pharma | Phase 3 |
| Completed | Study of CBME in the Relief of Painful Diabetic Neuropathy NCT00238550 | Sheffield Teaching Hospitals NHS Foundation Trust | Phase 2 |
| Completed | A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination Fo NCT00904202 | Endo Pharmaceuticals | Phase 4 |
| Completed | VEGF Gene Transfer for Diabetic Neuropathy NCT00056290 | Losordo, Douglas, M.D. | Phase 1 / Phase 2 |
| Completed | A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic Neuralg NCT00904020 | Endo Pharmaceuticals | Phase 4 |