| Completed | A Study to Assess Collagenase Clostridium Histolyticum (CCH) in the Treatment of Plantar Fasciitis (PFA) Plantar Fasciitis | Phase 2 | 2024-01-03 |
| Active Not Recruiting | Study to Assess EN3835 in the Treatment of Plantar Fibromatosis (Also Known as Ledderhose Disease) Plantar Fibromatosis, Ledderhose Disease | Phase 3 | 2023-11-28 |
| Terminated | Real-World Data Study to Understand Effectiveness of Treatments in Peyronie's Disease Peyronie's Disease | — | 2023-06-20 |
| Terminated | Real-World Data Study to Understand Participant Treatment Outcomes for Dupuytren's Contracture Dupuytren's Contracture | — | 2023-06-14 |
| Completed | Study of Different Interventions to Reduce Bruising Following CCH-Aaes Treatment for Cellulite of the Buttocks Edematous Fibrosclerotic Panniculopathy, Cellulite | Phase 2 | 2022-06-15 |
| Completed | Long-Term Safety, Efficacy, and Durability of EN3835 in the Treatment and Retreatment of Plantar Fibromatosis Plantar Fibromatosis | Phase 3 | 2022-02-14 |
| Completed | Durability and Safety of CCH With Two Different Injection Techniques in Cellulite With Laxity Cellulite, Laxity; Skin, Edematous Fibrosclerotic Panniculopathy | — | 2022-01-25 |
| Completed | Efficacy, Safety, and Tolerability, of EN3835 vs Placebo in the Treatment of Plantar Fibromatosis Plantar Fibromatosis | Phase 2 | 2021-11-29 |
| Completed | Effects of Mitigation Treatments on Bruising of CCH-aaes Treatment of Buttock Cellulite Edematous Fibrosclerotic Panniculopathy (EFP), Cellulite | Phase 4 | 2020-12-28 |
| Terminated | Long-term Follow-up Durability (Efficacy) Study of EN3835 for the Treatment of AC of the Shoulder (Frozen Shou Adhesive Capsulitis, Frozen Shoulder | — | 2020-12-17 |
| Completed | CCH Treatment of Cellulite in the Presence of Dermal Laxity With Comparison Between Two (2) Different Injectio Edematous Fibrosclerotic Panniculopathy, Cellulite, Laxity; Skin | Phase 2 | 2020-10-01 |
| Completed | Safety and Efficacy of EN3835 in Participants With Frozen Shoulder Adhesive Capsulitis, Frozen Shoulder | Phase 2 | 2020-07-29 |
| Completed | A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hy Hypogonadism, Hypogonadism, Male, Hypogonadotropic Hypogonadism | Phase 4 | 2020-06-30 |
| Completed | Long-term Durability Study of Collagenase Clostridium Histolyticum (CCH) Edematous Fibrosclerotic Panniculopathy | — | 2020-05-06 |
| Completed | Histopathology Following CCH Injection Characteristics of Subcutaneous Tissue | Phase 2 | 2019-12-20 |
| Terminated | Impact of CCH Treatment of Buttock and Thigh Cellulite in Adult Women Cellulite, Edematous Fibrosclerotic Panniculopathy (EFP) | Phase 2 | 2019-11-20 |
| Completed | Real World CCH Study in Adult Females With Cellulite Edematous Fibrosclerotic Panniculopathy (EFP), Cellulite | Phase 3 | 2019-11-01 |
| Completed | Safety and Pharmacokinetics of Vasopressin in Healthy Volunteers Healthy Volunteer Safety Study | Phase 1 | 2019-10-10 |
| Completed | Durability and Safety of EN3835 in the Treatment of EFP (Cellulite) in Women Edematous Fibrosclerotic Panniculopathy | — | 2019-03-28 |
| Completed | Safety and Pharmacokinetics of a Single Dose of CCH (3.36 mg) in Subjects With EFP Edematous Fibrosclerotic Panniculopathy | Phase 1 | 2018-09-18 |
| Completed | Injection Techniques of Collagenase Clostridium Histolyticum (CCH) for the Treatment of EFP (Cellulite) Edematous Skin | Phase 2 | 2018-09-18 |
| Completed | Long-Term Study of EN3835 (CCH-aaes) in Edematous Fibrosclerotic Panniculopathy (Cellulite) Edematous Fibrosclerotic Panniculopathy, Cellulite | Phase 3 | 2018-04-26 |
| Completed | Effectiveness and Safety of EN3835 in the Treatment of Cellulite in Women Edematous Fibrosclerotic Panniculopathy (Cellulite) | Phase 3 | 2018-02-08 |
| Completed | Effectiveness and Safety of EN3835 in the Treatment of EFP (Cellulite) in Women Edematous Fibrosclerotic Panniculopathy (Cellulite) | Phase 3 | 2018-02-05 |
| Completed | Safety and Effectiveness of EN3835 in the Treatment of EFP in Women Edematous Fibrosclerotic Panniculopathy, Cellulite | Phase 2 | 2017-11-17 |
| Completed | EN3835 for the Treatment of Edematous Fibrosclerotic Panniculopathy (Commonly Known as Cellulite) Edematous Fibrosclerotic Panniculopathy, Cellulite | Phase 2 | 2016-10-05 |
| Terminated | Clinical Study to Evaluate the Effectiveness, Safety, and Tolerability of Oxymorphone Immediate Release (IR) O Post-Operative Pain, Acute Pain | Phase 3 | 2016-04-01 |
| Completed | EN3835 for the Treatment of Edematous Fibrosclerotic Panniculopathy (Commonly Known as Cellulite) Edematous Fibrosclerotic Panniculopathy, Cellulite | Phase 2 | 2016-02-01 |
| Completed | Long-term Safety, Curvature Deformity Characterization, and Immunogenicity Over Time in Subjects Previously Tr Peyronie's Disease | — | 2014-11-01 |
| Completed | An Open-label Study to Assess the Safety and Effectiveness of AA4500 in Combination With the ErecAid® Esteem® Peyronie's Disease | Phase 3 | 2014-10-01 |
| Completed | Phase 2a Dose-Ranging Study to Evaluate Safety and Effectiveness of AA4500 in Treatment of Dupuytren's Disease Dupuytren's Disease | Phase 2 | 2014-07-01 |
| Completed | Clinical Study for the Treatment of Adhesive Capsulitis of the Shoulder Adhesive Capsulitis, Frozen Shoulder | Phase 2 | 2013-11-01 |
| Completed | A Phase 2, Randomized, Double-blind, Placebo Controlled Dose Ranging Study of Repeat Doses of AA4500 for the T Edematous Fibrosclerotic Panniculopathy (EFP) | Phase 2 | 2013-10-01 |
| Suspended | Safety, Tolerability, Effectiveness, and Pharmacokinetic Data in Opioid-experienced Children Chronic Pain, Postsurgical Pain | Phase 3 | 2013-03-11 |
| Completed | Study in Stabilized Schizophrenic Patients to Evaluate the Pharmacokinetics of Risperidone and 9-Hydroxy (OH)- Schizophrenia | Phase 1 | 2012-10-01 |
| Completed | A Phase 3, Open-label Study of the Safety and Effectiveness of AA4500 Administered Twice Per Treatment Cycle f Peyronie's Disease | Phase 3 | 2012-09-01 |
| Completed | CORRECT: COmmunity RegistRy Study Evaluating Dupuytren's Contracture Treatment Dupuytren's Contracture | — | 2012-09-01 |
| Completed | Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's Contrac Dupuytren's Contracture | Phase 3 | 2012-09-01 |
| Completed | Retreatment of Recurrent Dupuytren's Contractures Dupuytren's Disease | Phase 4 | 2012-03-01 |
| Completed | Post Approval Commitment Study Dupuytren's Contracture | — | 2012-03-01 |
| Completed | The Safety, Effectiveness, and Pharmacokinetics of AA4500 for the Treatment of Edematous Fibrosclerotic Pannic Edematous Fibrosclerotic Panniculopathy, Cellulite | Phase 1 | 2012-01-01 |
| Completed | AA4500 for the Treatment of Adhesive Capsulitis of the Shoulder Adhesive Capsulitis, Frozen Shoulder | Phase 2 | 2011-11-01 |
| Completed | Pharmacokinetics of a Single Treatment Cycle of AA4500 0.58 mg in Men With Peyronie's Disease Peyronie's Disease | Phase 2 | 2011-09-01 |
| Completed | Administration of Two Injections for Multiple Dupuytren's Contractures Dupuytren's Contracture | Phase 3 | 2011-09-01 |
| Terminated | A Prospective Registry to Assess the Effectiveness and Local Tolerability of Intravesical Valrubicin in Subjec Bladder Cancer, CIS | — | 2011-05-01 |
| Terminated | Multi-center Study to Evaluate the Efficacy and Safety of Maintenance Therapy With Valrubicin Versus no Mainte Carcinoma in Situ, Transitional Cell Carcinoma, Non-muscle Invasive Bladder Cancer | Phase 3 | 2011-05-01 |
| Completed | Retrospective Chart Review of Valstar Carcinoma in Situ of Bladder | — | 2011-03-01 |
| Terminated | Long-term Safety and Efficacy Study of Octreotide Implant in Patients With Acromegaly Acromegaly | Phase 3 | 2011-02-01 |
| Completed | Effectiveness, Safety, and Tolerability Study of Oxymorphone Immediate Release (IR) Oral Liquid in Post Surgic Post Operative Pain | Phase 3 | 2010-12-13 |
| Completed | Time to Eugonadal Range, Time to Steady State and Drying Time Male Hypogonadism | Phase 3 | 2010-11-01 |
| Completed | A Study of AA4500 in Men With Peyronie's Disease Peyronie's Disease | Phase 3 | 2010-11-01 |
| Withdrawn | Effectiveness, Safety, and Tolerability Study of Oxymorphone Immediate Release (IR) Oral Liquid in Opioid Tole Chronic Pain | Phase 3 | 2010-10-01 |
| Completed | Study of AA4500 in the Treatment of Peyronie's Disease Peyronie's Disease | Phase 3 | 2010-10-01 |
| Completed | Study of AA4500 in the Treatment of Peyronie's Disease Peyronie's Disease | Phase 3 | 2010-09-01 |
| Completed | Longterm Observational Study in Subjects Treated With AA4500 in AUX-CC-854, 856, 857, 858 & 859 Dupuytren's Disease | — | 2009-07-01 |
| Terminated | Pharmacokinetics, Efficacy and Safety of an Octreotide Implant in Patients With Carcinoid Syndrome Carcinoid Syndrome | Phase 1 / Phase 2 | 2009-07-01 |
| Completed | Study to Compare Oxymorphone Extended-Release (Opana ER) Versus Oxycodone Controlled-Release (Oxycontin) Healthy | Phase 4 | 2009-06-01 |
| Completed | Open-Label Safety and Tolerability Study of Oxymorphone for Acute Postoperative Pain in Pediatric Subjects. Postoperative Pain | Phase 3 | 2009-02-17 |
| Completed | A Study to Assess the Efficacy and Safety of Pagoclone for Adults With Stuttering Stuttering | Phase 2 / Phase 3 | 2009-02-01 |
| Terminated | Open-Label Safety and Tolerability of Oxymorphone IR and ER in Opioid Tolerant Pediatric Subjects Chronic Pain | Phase 3 | 2008-11-17 |
| Terminated | Efficacy and Safety Study of Octreotide Implant in Patients With Acromegaly Acromegaly | Phase 3 | 2008-09-01 |
| Completed | The Safety and Effectiveness of AA4500 in Subjects With Peyronie's Disease Peyronie's Disease | Phase 2 | 2008-08-01 |
| Terminated | EN3285 for the Prevention or Delay of Oral Mucositis in Patients With Head and Neck Cancer Oral Mucositis, Head and Neck Cancer | Phase 3 | 2007-12-01 |
| Completed | AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease Advanced Dupuytren's Disease | Phase 3 | 2007-12-01 |
| Completed | Safety and Efficacy Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease Advanced Dupuytren's Disease | Phase 3 | 2007-10-01 |
| Completed | A Pharmacokinetic Study of AA4500 (XIAFLEX™, Proposed Name) in Subjects With Dupuytren's Contracture Dupuytren's Contracture | Phase 1 | 2007-09-01 |
| Completed | AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Dupuytren's Contracture Dupuytren's Contracture | Phase 3 | 2007-08-01 |
| Completed | A Study of Fortigel Testosterone Gel 2% in Males With Low Testosterone Hypogonadism | Phase 3 | 2007-08-01 |
| Completed | Non-US Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease Advanced Dupuytren's Disease | Phase 3 | 2007-08-01 |
| Completed | Study of Trospium Chloride Inhalation Powder (TrIP) in Patients With Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease | Phase 1 / Phase 2 | 2007-04-01 |
| Completed | Efficacy and Safety of the Lidoderm Patch Applied to Patients With Osteoarthritis of the Knee Osteoarthritis of the Knee | Phase 2 | 2007-03-01 |
| Completed | Open Label Study of Octreotide Implant in Patients With Acromegaly Acromegaly | Phase 2 | 2007-02-01 |
| Terminated | Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow o Tendonitis, Bursitis | Phase 3 | 2007-01-01 |
| Completed | Vantas Implant Retrieval Study Prostate Cancer | — | 2006-07-01 |
| Completed | Exploratory Study of Pagoclone in Men With Premature Ejaculation. Premature Ejaculation | Phase 2 | 2006-07-01 |
| Completed | Evaluating the Effect of Food on Absorption of Megace ES Pharmacokinetics, Bioavailability, Absorption | Phase 1 | 2006-06-01 |
| Completed | Long-term Safety Study of Intramuscular Injections of 750 mg and 1000 mg Testosterone Undecanoate in Hypogonad Hypogonadism, Primary Hypogonadism, Secondary Hypogonadism | Phase 3 | 2006-03-01 |
| Terminated | Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpa Carpal Tunnel Syndrome | Phase 3 | 2005-11-01 |
| Completed | Trial to Evaluate PRO 2000/5 Gels for the Prevention of Vaginally Acquired HIV Infection HIV Infections, Gonorrhea, Chlamydial Infections | Phase 3 | 2005-10-01 |
| Completed | Effectiveness And Safety Of Frovatriptan For The Management (Acute Treatment) Of Menstrual Migraine Menstrual Migraine (MM) Headaches | Phase 4 | 2005-09-01 |
| Completed | EXPRESS: Examining Pagoclone for Persistent Developmental Stuttering Study Persistent Developmental Stuttering | Phase 2 | 2005-04-01 |
| Completed | Evaluate Weight Gain Using 2 Different Formulations of Megestrol Acetate Oral Suspension for AIDS-related Weig HIV Infections, Cachexia, Anorexia | Phase 2 | 2004-12-01 |
| Completed | Efficacy and Safety of Oxmorphone Extended Release in Chronic Non-malignant Pain Chronic Pain | Phase 3 | 2004-11-01 |
| Completed | Efficacy and Safety of Oxymorphone Extended Release in Opioid-Experienced Patients With Chronic Non-Malignant Chronic Pain | Phase 3 | 2004-10-01 |
| Completed | A Controlled Trial to Investigate the Efficacy and Safety of Frovatriptan to Prevent Menstrual Migraine Migraine | Phase 3 | 2004-10-01 |
| Completed | Efficacy and Safety of Oxymorphone Immediate Release in Post-surgical Acute Pain Acute Pain | Phase 3 | 2004-09-01 |
| Completed | Histrelin Subcutaneous Implant in Children With Central Precocious Puberty Central Precocious Puberty | Phase 3 | 2004-09-01 |
| Completed | Pilot Study of Lidocaine 5% Patch Versus Placebo in Patients With Osteoarthritis Pain of the Knee Osteoarthritis, Knee | Phase 2 | 2004-08-01 |
| Completed | A Study Comparing The Efficacy And Safety Of Lidocaine 5% Patch With Placebo In Patients With Chronic Axial Lo Chronic Low Back Pain | Phase 2 | 2004-08-01 |
| Terminated | Lidocaine Patch 5% Versus Celecoxib 200 mg in Chronic Axial Low Back Pain Chronic Low Back Pain | Phase 4 | 2004-07-01 |
| Terminated | Lidocaine Patch Versus Celecoxib in Pain From Osteoarthritis of the Knee Osteoarthritis of the Knee | Phase 4 | 2004-06-01 |
| Completed | Safety and Tolerability of Frovatriptan to Prevention of Menstrually Associated Migraine (MAM) Headaches Migraine | Phase 3 | 2003-12-01 |
| Completed | Oxymorphone Extended Release in Patients With Cancer or Neuropathic Pain Chronic Pain, Neuropathic Pain, Cancer | Phase 3 | 2003-08-01 |
| Completed | Oxymorphone Extended Release (ER) in Opioid-Naive Patients With Chronic Pain Pain, Chronic Disease | Phase 3 | 2003-06-01 |
| Completed | Pilot Study of the Efficacy and Safety of Lidoderm Patch in the Treatment of Low Back Pain Chronic Low Back Pain | Phase 4 | 2003-04-01 |
| Completed | Post-operative Efficacy and Safety Study Post-operative Pain | Phase 3 | 2003-04-01 |
| Completed | A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination Fo Postherpetic Neuralgia, Diabetic Neuropathy, Complex Regional Pain Syndrome | Phase 4 | 2003-01-01 |
| Completed | A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic Neuralg Postherpetic Neuralgia, Diabetic Neuropathy, Low Back Pain | Phase 4 | 2002-06-01 |
| Completed | Lidoderm® (Lidocaine Patch 5%) in Diabetic and Idiopathic Neuropathy Diabetes | Phase 4 | 2002-04-01 |
| Completed | Topical Lidocaine Patch in Low Back Pain Acute and Chronic Non-radicular LBP | Phase 4 | 2002-03-01 |
| Completed | A Randomized Trial of Frovatriptan for the Intermittent Prevention of Menstrual Migraine Menstrually Associated Migraine | Phase 3 | 2001-06-01 |
| Completed | Open Label Assessment of Long-Term Safety and Utility Pain | Phase 3 | 2001-04-01 |
| Completed | Open-Label Extension to Evaluate the Long-Term Safety, Tolerability and Analgesic Efficacy Cancers, Pain, Lower Back Pain | Phase 3 | 2001-03-01 |
| Completed | Study of Histrelin Subdermal Implant in Patients With Prostate Cancer Prostate Cancer, Adenocarcinoma of the Prostate | Phase 3 | 2000-05-01 |
| Completed | Study to Evaluate Efficacy and Safety of Histrelin Subdermal Implant in Men With Advanced Prostate Cancer Prostate Cancer, Adenocarcinoma of the Prostate | Phase 3 | 2000-04-01 |
| Completed | Intravesical AD 32 (Valrubicin) in Patients With Carcinoma in Situ (CIS) of the Bladder Who Have Failed or Hav Carcinoma in Situ, Bladder Cancer | Phase 2 / Phase 3 | 1993-11-01 |