Clinical Trials Directory

Trials / Completed

CompletedNCT00475514

A Controlled Trial to Investigate the Efficacy and Safety of Frovatriptan to Prevent Menstrual Migraine

A Double-blind, Placebo-controlled, Parallel Group Study to Assess the Efficacy, and Safety of Oral Frovatriptan in the Prevention on Menstrually-related Migraine (MRM) Headaches in a 'Difficult to Treat' Population

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
500 (actual)
Sponsor
Endo Pharmaceuticals · Industry
Sex
Female
Age
15 Years
Healthy volunteers
Not accepted

Summary

Although the predictability of an MRM headache attack lends itself to preventative treatment, there are currently no drugs specifically indicated for the prevention of MM. Such preventative therapies might be administered either short term (during the time around the period otherwise known as the peri-menstrual period or PMP) or continuously throughout the menstrual cycle. Frovatriptan has been developed for the management of migraine and is already licensed for use as an acute treatment for this condition. Previous well controlled clinical trials have highlighted the potential of frovatriptan as a short-term preventative medication for MM. This clinical trial was meant to further explore this indication for frovatriptan in an expanded population.

Detailed description

See above

Conditions

Interventions

TypeNameDescription
DRUGFrovatriptan 2.5mg QD
DRUGFrovatriptan 2.5 mg BID
DRUGplacebo

Timeline

Start date
2004-10-01
Primary completion
2006-03-01
Completion
2006-03-01
First posted
2007-05-21
Last updated
2024-01-02

Source: ClinicalTrials.gov record NCT00475514. Inclusion in this directory is not an endorsement.