| Suspended | Observational Study to Assess Migraine Prediction Tool NCT05523310 | Theranica | — |
| Suspended | Vibratory Stimulation for the Treatment of Chronic Pain NCT04069572 | Stanford University | N/A |
| Not Yet Recruiting | Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding Pain NCT07513662 | University of Colorado, Denver | N/A |
| Not Yet Recruiting | Migraine and Endometriosis: The FEMININE Study NCT07519343 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Not Yet Recruiting | Bilateral Embolization of the Middle Meningeal Arteries for Refractory Chronic Migraine NCT07223008 | Johns Hopkins University | N/A |
| Not Yet Recruiting | A Feasibility Trial of Virtual Reality Neurofeedback for Adolescents With Migraine NCT07454798 | Children's Mercy Hospital Kansas City | N/A |
| Not Yet Recruiting | Headache Prevalence and Phenotype in Myelin Oligodendrocyte Glycoprotein Antibody -Associated Disease (MOGAD) NCT07479212 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Enrolling By Invitation | Pericranial and General Sensitivity in Patients With Primary Headache NCT07514208 | Universitat Internacional de Catalunya | — |
| Not Yet Recruiting | Effectiveness of Manual Lymphatic Drainage in the Physiotherapeutic Treatment of Migraine NCT07425041 | Camilo Jose Cela University | N/A |
| Not Yet Recruiting | Selective Activation of the Adrenomedullin Receptors in Migraine NCT07451769 | Danish Headache Center | N/A |
| Recruiting | Tryptophan as a Modulating Factor in the Antimigraine Efficacy of Triptans NCT07177885 | University Hospital, Clermont-Ferrand | — |
| Recruiting | Aerobic Exercise and Its Impact on Sensory, Musculoskeletal, and Psychosocial Aspects in Migraine NCT06716489 | University of Sao Paulo | N/A |
| Not Yet Recruiting | Filter Lenses for the Prevention of Migraine Attacks NCT06161129 | Rune Skovgaard Rasmussen | N/A |
| Not Yet Recruiting | Effect of Transcutaneous Auricular Trigeminal Nerve Stimulation on Migraine NCT07457268 | Ordu University | N/A |
| Recruiting | MIGRAFIT: Evaluating a Group Therapy Program Combining Physical Activity, Progressive Muscle Relaxation and Ps NCT07419607 | Medical University Innsbruck | N/A |
| Active Not Recruiting | Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence Study NCT07487701 | Theranica | N/A |
| Not Yet Recruiting | App-Based Migraine Treatment: The Health enSuite Study NCT06797076 | IWK Health Centre | N/A |
| Not Yet Recruiting | Impact of GON PRF on Central Sensitization in Migraine Patients NCT07343427 | Ankara City Hospital Bilkent | N/A |
| Withdrawn | Middle Meningeal Artery Embolization for Chronic Migraine NCT07044648 | Wake Forest University Health Sciences | N/A |
| Not Yet Recruiting | Multimodal Brain Function in Migraine Patients With Patent Foramen Ovale NCT07343154 | Second Xiangya Hospital of Central South University | — |
| Recruiting | Study to Assess the Real-World Effectiveness of Ubrogepant in Adult Participants When Treating During the Prod NCT07310290 | AbbVie | — |
| Withdrawn | The Sequestration of Holistic Stress Management Techniques for Adults NCT06098755 | Goddess Zena I. Jones | N/A |
| Recruiting | Phase II Trial of PRT-064040 Nasal Spray for the Treatment of Migraine in Adults NCT07304518 | Sichuan Purity Pharmaceutical Technology Co., Ltd. | Phase 2 |
| Recruiting | Stimulation of External Carotid Artery Circulation NCT07402954 | The University of Texas Medical Branch, Galveston | N/A |
| Completed | Treatment Patterns Among US Veterans Using Remote Electrical Neuromodulation (REN) for Migraine Treatment NCT07336420 | Theranica | Phase 4 |
| Active Not Recruiting | Nerivio Efficacy Under High-Frequency Use NCT07336056 | Theranica | Phase 4 |
| Not Yet Recruiting | Basic Body Awareness Therapy in Individuals With Migraine NCT07328685 | Mustafa Kemal University | N/A |
| Active Not Recruiting | Desvenlafaxine for Preventive Treatment of Frequent Migraines NCT07385755 | Tongji Hospital | N/A |
| Not Yet Recruiting | Dietary Intervention for Migraine Relief NCT07360405 | American University | N/A |
| Enrolling By Invitation | Assessment of the Impact of Headache on the Employee Population of Libbs Pharmaceutical Ltd NCT07295587 | Libbs Farmacêutica LTDA | — |
| Recruiting | Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines NCT06904287 | Wake Forest University Health Sciences | Phase 3 |
| Enrolling By Invitation | App-based Breathing Program for Migraine Relief NCT07297901 | Arizona State University | N/A |
| Not Yet Recruiting | Motor Evoked Potential and Cortical Silent Period in Migraine NCT07250464 | Istanbul Gelisim University | N/A |
| Recruiting | Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Knee Osteoarthritis(OA) NCT07347028 | Beijing Tiantan Hospital | N/A |
| Not Yet Recruiting | "Personalized Physiotherapy for Migraine: Effects on Pain, Fatigue, and Physical Function" NCT07261384 | Hacettepe University | N/A |
| Not Yet Recruiting | A Dual Intervention in Migraine Treatment: Tens and Exercise NCT07125820 | Suleyman Demirel University | N/A |
| Active Not Recruiting | Consistency of Response With Rimegepant in Acute Treatment of Migraine NCT06898047 | Pfizer | — |
| Active Not Recruiting | Multicenter, Double-blind, and Randomized Controlled Trial of Ultra-Distal TENS Device for Migraine Treatment NCT07451158 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | Cabergoline for Episodic Migraine NCT07072910 | Aarhus University Hospital | Phase 2 |
| Active Not Recruiting | The Impact of Acupuncture on Biomarkers of Brain Injury and Inflammatory Response in Migraine NCT07292506 | University Medical Centre Ljubljana | N/A |
| Recruiting | Intra-Nasal Mechanical Stimulation (INMEST) as a Potential Preventative Treatment for Migraine NCT07279623 | Abilion Medical Systems AB | N/A |
| Not Yet Recruiting | Evaluation of a Mind-Body Based Approach for Chronic Pain Treatment NCT07143396 | University of the Fraser Valley | N/A |
| Enrolling By Invitation | Coping Skills for Migraine: A 6-Month Program NCT07163559 | Hacettepe University | N/A |
| Withdrawn | A Study to Learn About Zavegepant as a Treatment for Multiple Migraine Attacks in Adult Participants NCT06103734 | Pfizer | Phase 3 |
| Active Not Recruiting | Evaluation of MIG-SPRAY Treatment on Migraine NCT07100496 | University Hospital, Clermont-Ferrand | Phase 4 |
| Not Yet Recruiting | Predictors of GON Blockade Success in Migraine NCT07170111 | Başakşehir Çam & Sakura City Hospital | N/A |
| Recruiting | Rimegepant as Preemptive Treatment for Predictable Trigger-Induced Migraine in Adult Patients in the US NCT07301008 | Medstar Health Research Institute | Phase 4 |
| Recruiting | Comparative Efficacy of Flunarizine and Propanolol in Pediatric Migraine NCT07354126 | Muhammad Aamir Latif | N/A |
| Completed | Effectivity and Safety of GB20 Acupoint Pharmacopuncture With Lidocaine 2% on Migraine Patients NCT07067853 | Indonesia University | N/A |
| Recruiting | Neuropsychological Profile Characterization in Patients With Migraine: Cognitive Functioning and Psychological NCT07233941 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | — |
| Completed | Facilitators and Barriers to Eptinezumab Administration in Thailand NCT07035197 | Chulalongkorn University | — |
| Not Yet Recruiting | Comparative Study of Nutraceuticals vs. Conventional Prophylactic Therapy in the Management of Migraine NCT07147972 | Fayoum University | Phase 3 |
| Not Yet Recruiting | Effect of Manual Therapy on Migraine in Postmenopausal Women NCT07127107 | Cairo University | N/A |
| Recruiting | Efficacy of Xeomin for Migraines in Patients With Traumatic Brain Injuries vs. Anomalous Health Incidents NCT07267819 | Uniformed Services University of the Health Sciences | — |
| Not Yet Recruiting | Efficacy of Non-Invasive Neuromodulation on Pain in Migraine NCT07081685 | University Hospital, Clermont-Ferrand | N/A |
| Not Yet Recruiting | Individualized Location-based rTMS for Migraine Treatment: A Multicenter Clinical Study NCT07086274 | First Affiliated Hospital of Zhejiang University | N/A |
| Not Yet Recruiting | Turkish Version of the Headache Screening Questionnaire NCT07048132 | Başakşehir Çam & Sakura City Hospital | — |
| Recruiting | Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study NCT06972056 | Mayo Clinic | Phase 4 |
| Completed | AI Chatbot for Migraine Management in Hong Kong Women NCT06920602 | The Hong Kong Polytechnic University | N/A |
| Not Yet Recruiting | Effectiveness of Auricular Acupuncture for Migraine NCT07024511 | Universiti Tunku Abdul Rahman | N/A |
| Recruiting | Cocoa Extract for Migraine Trial NCT06808230 | Brigham and Women's Hospital | N/A |
| Not Yet Recruiting | Effects of Progressive Muscle Relaxation Training Applied in Addition to Aerobic Exercise Training in Individu NCT07003711 | Mardin Artuklu University | N/A |
| Completed | Evaluation of a Wearable Device for Acute Treatment of Migraines NCT07015125 | Hinge Health, Inc | N/A |
| Completed | A Study to Learn About PRT-064040 Nasal Spray in Healthy Adult Subjects NCT07016516 | Sichuan Purity Pharmaceutical Technology Co., Ltd. | Phase 1 |
| Recruiting | The Nordic Chronic Migraine Trial of CGRP Monoclonal Antibody and Onabotulinumtoxin A Dual Therapy Compared to NCT07040813 | Oslo University Hospital | Phase 3 |
| Withdrawn | Healthy Living Partnerships for Veterans With Migraine NCT04373330 | Wake Forest University Health Sciences | N/A |
| Not Yet Recruiting | Effectiveness of Tai Chi and Acupuncture on Migraine Attack Prevention and Brain White Matter Changes: A Non-I NCT06967909 | The Hong Kong Polytechnic University | N/A |
| Completed | Cervical Stability and Body Awareness in Migraine NCT07116590 | Hacettepe University | — |
| Recruiting | Mechanistic Studies of Psilocybin in Headache Disorders NCT06464367 | Yale University | EARLY_Phase 1 |
| Recruiting | Neuro-Complex & Multi Supplements for Migraine Prevention NCT07015411 | Benfida, a department of Handi-Move | N/A |
| Recruiting | Substance P-Induced Migraine Attacks Without Aura NCT06959004 | Danish Headache Center | N/A |
| Completed | Nerivio Efficacy by Time of Treatment Onset NCT06976723 | Theranica | Phase 4 |
| Withdrawn | Study of Wireless Nerve Stimulation in the Treatment of Chronic Migraine NCT02725554 | Curonix LLC | Phase 3 |
| Not Yet Recruiting | Efficacy and Safety of Oral NBP Soft Capsules for the Prevention of Episode Migraine Attacks in Adult Migraine NCT06968429 | Chinese PLA General Hospital | N/A |
| Not Yet Recruiting | 0.5% Bupivacaine Lower Cervical Intramuscular Injection vs IV Medications for Headache Treatment NCT06937385 | HCA Florida North Florida Hospital | Phase 3 |
| Recruiting | Combined Effects of Green Light and Transcranial Direct Current Stimulation in Migraine Patients. NCT06943625 | Riphah International University | N/A |
| Recruiting | MMA Embolization for Refractory Chronic Migraine NCT06735833 | Cerenovus, Part of DePuy Synthes Products, Inc. | N/A |
| Active Not Recruiting | Omega-3 Supplementation for Pediatric Migraine NCT06899074 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimul NCT06961864 | University of Minnesota | N/A |
| Not Yet Recruiting | Use of the Combination of Sumatriptan and Naproxen in the Acute Treatment of Migraine: Real World Evidence Stu NCT06868953 | IRCCS San Raffaele Roma | — |
| Completed | Cooling to Alleviate Migraine #3 NCT06874361 | Mi-Helper, Inc. | N/A |
| Active Not Recruiting | Compare the Effectiveness of nVNS and TENS on Pain and Quality of Life in Patients of Migraine NCT07055776 | Superior University | N/A |
| Enrolling By Invitation | Evaluation of Pain Thresholds in Migraine Patients After Inhalation of Essential Oils: a Randomized Clinical T NCT07493434 | University of Sao Paulo | N/A |
| Recruiting | Bilateral Middle Meningeal Artery Lidocaine Infusion for Chronic Debilitating Migraines NCT07061847 | Northwell Health | Phase 2 |
| Recruiting | New Methods for Evaluating Preventive Migraine Treatment NCT07071506 | University of Aarhus | N/A |
| Recruiting | High-field MR Imaging in Migraine, Visual Snow and Epilepsy NCT05524493 | University of Zurich | — |
| Enrolling By Invitation | Muscle Function and Tenderness Differences in Headache Patients NCT06859463 | Danish Headache Center | — |
| Completed | Safety and Efficacy Trial of MTX101 2mg for the Acute Treatment of Migraine in Adults NCT06728553 | Manistee Therapeutics | Phase 2 |
| Enrolling By Invitation | The Effect of a Video-Based Exercise Program on Migraine Symptoms NCT06871852 | Bandırma Onyedi Eylül University | N/A |
| Active Not Recruiting | Study to Assess Function and Satisfaction of Oral Ubrogepant in Adult Participants After Multiple Migraine Att NCT06692881 | AbbVie | — |
| Recruiting | Endometriosis and Migraine NCT06785129 | Washington University School of Medicine | — |
| Completed | Machine Learning Assessment of Next-Day Migraine Likelihood NCT07227194 | Theranica | — |
| Completed | The Effect of Cervical Stabilization Training in Individuals With Migraine NCT06991504 | Zonguldak Bulent Ecevit University | N/A |
| Recruiting | A Pragmatic Trial of Machine Prescription for Migraine NCT06893874 | Norwegian University of Science and Technology | — |
| Withdrawn | Single-Site Study of Naltrexone/Acetaminophen for the Acute Treatment of Migraine: A Phase 2 Randomized Trial NCT05685225 | Allodynic Therapeutics, Inc | Phase 2 |
| Completed | Synergistic Impact of Postural Correction Interventions and Sustained Natural Apophyseal Glides in Migraine NCT07403175 | Riphah International University | N/A |
| Completed | Head Awareness in Chronic Migraine Patients NCT06857383 | Bozok University | — |
| Completed | Tampa Kinesiophobia Scale Modified for Headache NCT06857357 | Bozok University | — |
| Not Yet Recruiting | Integrative and Complementary Therapy for Episodic Migraine and Tension-type Headache NCT06764914 | Kliniken Essen-Mitte | — |
| Not Yet Recruiting | Exploring Clinical Trial Experiences of Patients With Migraine NCT05675189 | Power Life Sciences Inc. | — |
| Recruiting | Carotid Sinus Massage in Trendelenburg Position for Headache Relief NCT06745648 | Hospital Municipal Pedro T. Orellana | N/A |
| Active Not Recruiting | A Trial of Eptinezumab in Participants With Migraine and Insufficient Response to Anti-CGRP Medications NCT06701526 | H. Lundbeck A/S | Phase 4 |
| Recruiting | Assessment of the Effectiveness of Virtual Reality as a Learning Tool for Relaxation Techniques in Reducing Pe NCT06921109 | University of Liege | N/A |
| Recruiting | Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics NCT06624137 | Yale University | — |
| Not Yet Recruiting | The Real-world Study of Rimegepant Treatment in Female Migraine Patients of China NCT06728345 | The First Affiliated Hospital of Soochow University | — |
| Completed | Nerivio Long-term Usage in Patients With Migraine NCT06738056 | Theranica | — |
| Recruiting | Observational Study of Oral Atogepant to Evaluate Real-World Effectiveness in Adult Participants With Migraine NCT06543914 | AbbVie | — |
| Recruiting | External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy NCT06788977 | Cefaly Technology | — |
| Withdrawn | Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for Preventive Treatment of Migraine NCT05804396 | Neurolief Ltd. | N/A |
| Recruiting | A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine NCT06616194 | Pfizer | Phase 3 |
| Not Yet Recruiting | The Impact of Greater Occipital Nerve and Stellate Ganglion Block Treatments on Sleep in Chronic Headache Mana NCT06646081 | Ankara Etlik City Hospital | N/A |
| Recruiting | The Effectiveness of Eptinezumab During a Migraine Attack (the BE-FREE Study) NCT06628921 | University of Florence | — |
| Completed | Comparison of Patient-reported Outcomes for Rimegepant and Triptans in the 2023 US National Health and Wellnes NCT06680206 | Pfizer | — |
| Completed | Efficacy and Safety Trial of BHV-2100 for the Acute Treatment of Migraine NCT06603623 | Biohaven Therapeutics Ltd. | Phase 2 |
| Completed | the Effect of Reflexology in Migraine Patients NCT06828315 | Muş Alparslan University | N/A |
| Recruiting | A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Epis NCT06602479 | AbbVie | Phase 2 |
| Recruiting | Improving the Perception of Stress and Mutuality in Caregivers (MI-DEAR Study) of Migraine Patients With Depre NCT07029126 | Fondazione Policlinico Universitario Campus Bio-Medico | — |
| Not Yet Recruiting | Migraine Among Sohag University Students NCT06536920 | Sohag University | — |
| Not Yet Recruiting | Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care NCT06499116 | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | Phase 4 |
| Not Yet Recruiting | Eptinezumab as an Adjunct to Standard of Care for Migraine in an Acute Emergency Context NCT06428838 | Dr George Medvedev | Phase 3 |
| Recruiting | Post-Marketing Study to Assess the Safety and Effectiveness of Oral Atogepant in Korean Adult Participants for NCT06603558 | AbbVie | — |
| Enrolling By Invitation | Self-acupuncture for Migraines Feasibility Study NCT06716944 | University of West London | Phase 1 / Phase 2 |
| Completed | A Trial Investigating Lu AG09222 With Ubrogepant in Participants With Migraine NCT06578585 | H. Lundbeck A/S | Phase 1 |
| Recruiting | Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Me NCT06417775 | AbbVie | Phase 3 |
| Recruiting | AI-assisted Migraine Education: Efficacy, Safety and Patients' Acceptance NCT06507150 | Ente Ospedaliero Cantonale, Bellinzona | N/A |
| Recruiting | A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache NCT06473597 | Antonios Likourezos | Phase 4 |
| Active Not Recruiting | Exploring the Effect of the Transcendental Meditation® Technique on Migraine Frequency and Functionality: A Si NCT06695156 | Maharishi International University | N/A |
| Active Not Recruiting | ARISE-A Chinese Real-world Study of Rimegepant for the Acute Treatment of Migraine NCT06439628 | Chinese PLA General Hospital | — |
| Recruiting | BE WELL With Migraine: Brain Education and WELLness With Migraine NCT05987592 | Wake Forest University Health Sciences | N/A |
| Recruiting | Impact of Combined Oral Contraceptive Pills on Migraine NCT06509503 | Kafrelsheikh University | Phase 4 |
| Completed | A Real-world, Prospective Observational Study of Rimegepant ODT for the Acute Treatment of Migraine Attacks in NCT06467370 | Pfizer | — |
| Completed | Short-Term Effects of Acupuncture on Balance, and Quality of Life in Women With Migraine: A Pilot Study NCT07145242 | Laura Zaliene | N/A |
| Not Yet Recruiting | Music and Imagery for Veterans With Migraine Headache NCT06440876 | Richard L. Roudebush VA Medical Center | N/A |
| Completed | A Study to Learn About the Benefit of Rimegepant Versus Triptans in Migraine Buddy App Users. NCT06532357 | Pfizer | — |
| Terminated | Migraine Survey in Gulf Region NCT06237062 | Novartis Pharmaceuticals | — |
| Completed | Mindfulness-Based Intervention for Adolescents With Chronic Migraine NCT06414109 | University of Colorado, Denver | N/A |
| Completed | Follow-up of Migraine Patients on Eptinezumab NCT06446804 | Centre Hospitalier Universitaire de Nīmes | — |
| Active Not Recruiting | Migraine Research with Smartwatch Application NCT06862544 | Heinrich-Heine University, Duesseldorf | — |
| Active Not Recruiting | Comparision of the Analgesic Effects of Intravenous Ibuprofen and Tenoxicam in Acute Migraine Attack NCT06786650 | Haydarpasa Numune Training and Research Hospital | Phase 4 |
| Active Not Recruiting | Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine P NCT06414044 | University of Florence | — |
| Unknown | The Link Between Human Cytomegalovirus Gene Expression and Glutamate Level in Migraine;Relation to Vitamin D D NCT06304948 | Assiut University | — |
| Recruiting | High-Density EEG-MEG-wearable EEG: Comparison of Quantitative Electroencephalographic Indicators as Neurophysi NCT06938178 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | — |
| Recruiting | Psychosomatic Factors Influencing the Efficacy of Holistic Care for Migraine NCT06334237 | Changhua Christian Hospital | — |
| Recruiting | Investigation of Functional Brain Features in Women with Migraine NCT06470958 | Danish Headache Center | — |
| Enrolling By Invitation | Migraine Medication Effects on Urinary Symptoms NCT06212661 | The Cleveland Clinic | — |
| Recruiting | A Proteomic Analysis for Understanding the Link Between Migraine and Cardiovascular Disease NCT06372509 | Centro Cardiologico Monzino | — |
| Active Not Recruiting | A Dose-finding Trial With Lu-AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Trea NCT06323928 | H. Lundbeck A/S | Phase 2 |
| Recruiting | Zonisamide Versus Topiramate in Migraine NCT06347497 | Kafrelsheikh University | Phase 3 |
| Recruiting | Zonisamide Versus Propranolol in Migraine NCT06361446 | Kafrelsheikh University | Phase 3 |
| Recruiting | Migraine and Neuropathic Pain in Osteoarthritis NCT06224959 | University Hospital, Clermont-Ferrand | — |
| Recruiting | RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment NCT06409832 | University of Florence | — |
| Recruiting | Effectiveness and Tolerability of Eptinezumab NCT06409845 | University of Florence | — |
| Recruiting | Study of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With Migraine NCT06241313 | AbbVie | Phase 3 |
| Recruiting | Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Pre NCT06401642 | Mayo Clinic | Phase 4 |
| Unknown | Impementation of the Exercise Recommendations for the Treatment of Primary Headaches: A Qualitative Approach t NCT06127888 | Fundació Universitària del Bages | — |
| Active Not Recruiting | Treatment for Migraine and Mood NCT05576467 | Amanda Shallcross | N/A |
| Active Not Recruiting | Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45 NCT06173661 | Brigham and Women's Hospital | Phase 4 |
| Recruiting | A Comparison of Biodegradable and Metal Occluders in Patients With PFO and Migraine NCT06203873 | Chinese Academy of Medical Sciences, Fuwai Hospital | N/A |
| Active Not Recruiting | Clinical and Neurophysiological Effects of tDCS to Visual and Motor Cortex in Migraine NCT06468189 | Istanbul Medipol University Hospital | N/A |
| Completed | Psychometric Properties of the Turkish Version of the HANA in Migraine NCT06675279 | Tokat Gaziosmanpasa University | — |
| Recruiting | Emgality for Migraine in Breastmilk NCT06085144 | University of California, San Francisco | — |
| Recruiting | Ultrasound Guided Block of Stellate Ganglion Versus Greater Occipital Nerve in Resistant Migraine and Correlat NCT06662461 | Ain Shams University | N/A |
| Recruiting | A Registry Study on Rimegepant for the Treatment of Migraine Participants in Guangdong-Hong Kong-Macao Greater NCT06221267 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | — |
| Unknown | Green Light and Transcranial Direct Current Stimulation in Migraine Patients NCT06212869 | Riphah International University | N/A |
| Completed | The Prevalence of Osmophobia in Migraine and Tension-Type Headache Patients and Its Association With Migraine NCT07329127 | National and Kapodistrian University of Athens | — |
| Unknown | Unwinding Anxiety for Migraine: Pilot NCT06150612 | Yeshiva University | N/A |
| Recruiting | Real-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine NCT07159750 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Unknown | The Effectiveness of Cervical Kinesio Taping in Migraine NCT06203678 | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | N/A |
| Unknown | Efficacy of Flunarizine Vs Amitriptyline in Prophylaxis of Migraine Prophylaxis NCT06162819 | Shalamar Institute of Health Sciences | N/A |
| Recruiting | Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale NCT06953622 | Peking University Third Hospital | — |
| Recruiting | Comparative Effects of Theragun Percussion Therapy and Compression Therapy in The Patients With Migraine NCT06504537 | Riphah International University | N/A |
| Recruiting | OnaBotulinumtoxin-A in Chronic Migraine Patients With Short or Long Disease History (the BACH Study) NCT06537700 | Fondazione Policlinico Universitario Campus Bio-Medico | — |
| Unknown | Vagal Nerve Stimulation and Pain Frequency, Intensity in Chronic Migraine NCT06191016 | Riphah International University | N/A |
| Unknown | Sequential, Multiple Assignment, Double Randomized Preference, Migraine Behavioral Trial NCT06170281 | Stanford University | N/A |
| Unknown | Migraine Headache Mitigation Utilizing Avulux NCT06149000 | Kaiser Permanente | N/A |
| Unknown | Real-world Effectiveness and Tolerability of Triptans-Ditans-Gepants (TRIDIGEP) NCT06267664 | Hospital Clínico Universitario de Valladolid | — |
| Completed | A Study to Learn About Zavegepant as the Acute Treatment of Migraine in Asian Adults NCT05989048 | Pfizer | Phase 3 |
| Completed | NYU Langone Health Headache Center Learning Migraine Self-Management Techniques Study NCT06077812 | NYU Langone Health | N/A |
| Completed | Feasibility and Effectiveness of a Specific App to Delivery Mindfulness Sessions NCT05101837 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | Phase 4 |
| Completed | Mi-Helper Transnasal Cooling for Acute Treatment of Migraine NCT06051604 | CoolTech LLC | N/A |
| Recruiting | RELAXaHEAD for Headache Patients (Phase III) NCT06077838 | NYU Langone Health | N/A |
| Completed | German Translation and Cross-cultural Adaptation of the Headache Screening Questionnaire (HSQ) Followed by a T NCT05893004 | Markus J. Ernst | N/A |
| Recruiting | NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar NCT05669703 | National Institute of Mental Health (NIMH) | — |
| Unknown | Post-marketing Clinical Trial of Elexir(Trigeminal Nerve Electrical Stimulator) for the Acute Treatment of Mig NCT06170411 | Nu Eyne Co., Ltd. | N/A |
| Unknown | Volumetric MRI Brain in Patients With Migraine NCT06077448 | Assiut University | — |
| Recruiting | Migraine Attack Pain Phase Prediction Study NCT06459635 | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | — |
| Active Not Recruiting | Comparative Study of Oral Atogepant Versus Oral Topiramate to Assess Adverse Events in Adult Participants With NCT05748483 | AbbVie | Phase 3 |
| Unknown | Muscle Function and Strength Training of the Neck and Shoulder in Migraine and Tension-type Headache Patients. NCT06112587 | Danish Headache Center | N/A |
| Completed | Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology NCT06334796 | Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia | EARLY_Phase 1 |
| Recruiting | Migraine and High Flow Oxygenotherapy at the Emergency Department (MiOx) NCT04925414 | Centre Hospitalier Universitaire de Nice | Phase 4 |
| Completed | Acute Treatment of Migraine in Pre-Adolescents: Real-World Analysis of Remote Electrical Neuromodulation (REN) NCT06138756 | Theranica | — |
| Completed | Manageable Environmental Factors in Migraine NCT06304675 | Samsun University | — |
| Completed | The Effects of Prayer on Pain Thresholds and Scores of Anxiety and Depression in Patients With Migraine and Co NCT07143461 | University of Sao Paulo | N/A |
| Recruiting | Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs? NCT06016465 | Texas Tech University Health Sciences Center, El Paso | EARLY_Phase 1 |
| Completed | Comparison of Occipital Nerve and Sphenopalatine Ganglion Blockade NCT06243874 | Ankara University | N/A |
| Completed | Bioequivalence Study to Compare Ibuprofen/ Paracetamol Tablets (200mg Ibuprofen/ 500mg Paracetamol) Versus Nur NCT06180070 | Humanis Saglık Anonim Sirketi | Phase 1 |
| Recruiting | Responding With Evidence and Access for Childhood Headaches NCT05889624 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C) NCT06004388 | Click Therapeutics, Inc. | Phase 3 |
| Completed | Study of Oral Atogepant Tablets to Assess Change in Disease Activity in Adult Japanese Participants With Episo NCT05861427 | AbbVie | Phase 3 |
| Completed | A Prospective Post-marketing Observational Study Assessing the Safety and Efficacy of Nerivio for Migraine Pre NCT05940870 | Theranica | — |
| Completed | Cervical Repositioning Error in Chronic Migraine NCT05933590 | Ahram Canadian University | — |
| Unknown | The Living With a Long-Term Condition Study NCT06072287 | King's College London | — |
| Unknown | Intravenous Fluids in Pediatric Migraine NCT06182098 | Dayton Children's Hospital | N/A |
| Completed | An Observational Study to Assess Ubrogepant Tablets and Atogepant Tablets to Treat Migraine in Adult Participa NCT05827887 | AbbVie | — |
| Recruiting | Gepant treAtments: EffectIveNess and tolERability (GAINER) NCT05903027 | University of Florence | — |
| Completed | Efficacy and Safety of Middle Meningeal Artery Embolization for Treatment of Intractable Migraine NCT06029153 | The Affiliated Hospital Of Guizhou Medical University | N/A |
| Completed | Ditan Acute tReatments: Effectiveness and Tolerability (DART) NCT05903040 | University of Florence | — |
| Completed | Effectiveness of a Dialogue-based Online Intervention Against Migraine NCT04276142 | Gaia AG | N/A |
| Completed | Real-life Study of the Efficacy of Management of Migraine Patients After Failure of 2 Prophylactic Treatments NCT05947123 | Centre Hospitalier Régional Metz-Thionville | — |
| Recruiting | Migraine in Adolescents NCT05654012 | Washington University School of Medicine | N/A |
| Completed | Comparison of Ketorolac at Three Doses in Children With Acute Pain NCT05641363 | Hamilton Health Sciences Corporation | Phase 3 |
| Completed | A Study to Learn About the Safety and Effects of Rimegepant to Prevent Migraine in Chinese Subjects. NCT05810038 | Pfizer | Phase 3 |
| Unknown | A Clinical Trial Evaluated the Safety and Tolerability, Pharmacokinetic and Pharmacodynamics Profile, and Immu NCT06158737 | Shanghai Junshi Bioscience Co., Ltd. | Phase 1 |
| Completed | Headache in Undergraduate Students and Biopsychosocial Status NCT05843760 | şeyda öztürk | — |
| Unknown | Coping Skills Training in Individuals With Migraine NCT05809375 | Hacettepe University | N/A |
| Recruiting | Study of the Glymphatic System in Migraine NCT05907655 | IRCCS San Raffaele | — |
| Recruiting | Study for Prevent Chronification Migraine Through Prediction of Response to Treatment With Anti-CGRP Antibodie NCT06459648 | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | — |
| Recruiting | Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Pat NCT07022496 | Ain Shams University | Phase 4 |
| Terminated | Nurse Intervention Trial NCT06200480 | Norwegian University of Science and Technology | N/A |
| Completed | The Effect of Laughter Therapy in Women NCT05804812 | Sinop University | N/A |
| Enrolling By Invitation | Comparison of Neuromodulatory Treatment of Migraine Headache with Acupuncture and Transcranial Direct Current NCT06834022 | University Medical Centre Ljubljana | N/A |
| Completed | Effects of Adding an Oculomotor Therapy Treatment in Patients With Migraine NCT05842642 | University of Jaén | N/A |
| Completed | Real World Data Analysis: Impact of High-Frequency REN Treatments As Migraine Preventive Therapy in Adolescenc NCT05769322 | Theranica | — |
| Completed | Study of Two Digital Therapeutics for the Prevention of Episodic Migraine NCT05853900 | Click Therapeutics, Inc. | N/A |
| Unknown | Comparison of Efficacy Between Combination of Amitriptyline-propranolol and Pizotifen for Migraine Prophylaxis NCT06158230 | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Phase 2 |
| Recruiting | Overlapping Pain Trajectory Study NCT05752396 | Children's Hospital Medical Center, Cincinnati | — |
| Completed | Real-World Evidence (RWE) Data Analysis of 1-year Consecutive Use of Remote Electrical Neuromodulation (REN) NCT05760638 | Theranica | — |
| Completed | Migraine Induction Properties of PACAP-38 After Eptinezumab in Migraine Without Aura Patients. NCT05635604 | Danish Headache Center | N/A |
| Enrolling By Invitation | A Study of Wearable Devices to Predict Migraines NCT05755945 | Mayo Clinic | N/A |
| Unknown | Stimulation-evoked Calcitonin Gene-Related Peptide (CGRP) as Biomarker of Migraine NCT05768828 | University Medicine Greifswald | — |
| Suspended | Dose-Ranging Trial of Inhaled Cannabis for Acute Migraine Treatment NCT05427630 | University of California, San Diego | Phase 2 |
| Recruiting | Clinical Trial of Endoscopically Guided Injection of Exparel (Bupivacaine) for the Treatment of Craniofacial P NCT04930887 | Stanford University | Phase 2 |
| Unknown | Greater Occipital Nerve Block Versus Pulse Radiofrequency in Migraine NCT06345326 | Adiyaman University Research Hospital | N/A |
| Completed | A Prospective Real World Study of Rimegepant in the Treatment of Migraine NCT05709106 | Ruijin-Hainan Hospital Shanghai Jiao Tong University School Of Medicine | — |
| Active Not Recruiting | Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine NCT05738213 | Washington University School of Medicine | N/A |
| Recruiting | Observational Study to Assess Adverse Events When Adult Female Participants Are Treated With Ubrelvy (Ubrogepa NCT05158894 | AbbVie | — |
| Unknown | Zolmitriptane as Prophylaxis for Chilhood Migraine NCT06089356 | Tanta University | Phase 4 |
| Completed | Diaphragm Relaxation Techniques, Diaphragmatic Breathing Exercises for Migraine Patients NCT07145372 | Seda Saka | N/A |
| Completed | Home-based Biofeedback for the Prevention of Migraine NCT05616741 | Nordic Brain Tech AS | N/A |
| Completed | Efficacy and Safety of Rizatriptan-Naproxen (10/550 Mg) in the Acute Treatment of Migraine NCT04384367 | Eurofarma Laboratorios S.A. | Phase 3 |
| Unknown | InfluenCEF Study: Study on the Headache Associated With Influenza Infection NCT05704335 | Hospital Clínico Universitario de Valladolid | — |
| Completed | An Observational Study to Assess Change in Disease Activity When Ubrogepant Tablets Are Combined With Atogepan NCT05653986 | AbbVie | — |
| Recruiting | Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification NCT06674772 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Completed | The Effect of Different Exercise Types on Migraine Frequency in Individuals With Migraine NCT05568004 | Ege University | N/A |
| Completed | Efficacy and Tolerability of Rimegepant for the Prevention of Migraine in Adults With History of Inadequate Re NCT05518123 | Pfizer | Phase 4 |
| Unknown | Habituation of the Nociceptive Blink Reflex in Experimentally Induced Migraine Attack NCT05718310 | IRCCS National Neurological Institute "C. Mondino" Foundation | N/A |
| Completed | The Impact of Migraine on Canadians' Productivity: A Real-World Pharmacy-Based Study NCT05556564 | PeriPharm | — |
| Completed | Efficacy and Tolerability of Rimegepant for the Acute Treatment of Migraine in Adults Unsuitable for Triptan U NCT05509400 | Pfizer | Phase 4 |
| Unknown | Comparison of the Effect of Medication Therapy in Alleviating Migraine With Patent Foramen Ovale NCT05546320 | Chinese Academy of Medical Sciences, Fuwai Hospital | Phase 4 |
| Completed | Efficacy of Fascia Exercises in Migraine Patients NCT06231615 | Ankara Yildirim Beyazıt University | N/A |
| Terminated | Tandem OnabotulinumtoxinA Galcanezumab Emerging Therapeutic Headache Elimination Research Study NCT05492695 | Diamond Headache Clinic | Phase 4 |
| Unknown | COMParison of the EffecT of dEvice Closure in Alleviating Migraine With PFO (COMPETE-2) NCT05561660 | Chinese Academy of Medical Sciences, Fuwai Hospital | Phase 4 |
| Unknown | Monoclonal CGRP Antibodies for Migraine Prevention - a Nationwide Real Life Study NCT05281770 | Austrian Migraine Registry Collaboration | — |
| Unknown | Probiotics as Adjunctive Migraine Prophylaxis NCT05042037 | Universiti Putra Malaysia | N/A |
| Completed | A Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label Period on Efficacy and Safety of Frema NCT05458011 | Teva Branded Pharmaceutical Products R&D, Inc. | Phase 3 |
| Recruiting | Physiotherapy Intervention for Migraine Symptoms NCT05741775 | Universiti Tunku Abdul Rahman | Phase 3 |
| Completed | Patent Foramen Ovale Closure in Migraine NCT06192173 | Haiyan Wang | — |
| Completed | Cabergoline as a Preventive Treatment for Chronic Migraine NCT05525611 | University of Aarhus | N/A |
| Unknown | Pilot Study for a Machine Learning Test for Migraine NCT05517200 | Headache Sciences Incorporated | — |
| Completed | Open-Label Study of AXS-07 for the Acute Treatment of Migraine in Adults With a Prior Inadequate Response to a NCT05550207 | Axsome Therapeutics, Inc. | Phase 3 |
| Recruiting | China HeadAche DIsorders RegiStry NCT05334927 | Beijing Tiantan Hospital | — |
| Unknown | Topiramate, Amitriptyline Monotherapy and Combination Therapy in Migraine Prophylaxis NCT05759845 | Dr. Reaz Mahmud | Phase 4 |
| Completed | Efficacy and Safety Study of Rimegepant for the Acute Treatment of Migraine in Japanese Subjects (Japan Only) NCT05399459 | Pfizer | Phase 3 |
| Completed | Efficacy and Safety Study of Rimegepant for Migraine Prevention in Japanese Subjects (Japan Only) NCT05399485 | Pfizer | Phase 3 |
| Completed | Investigation of the Effect of Cold Application in Migraine NCT05454826 | Eylül Pınar KISA | N/A |
| Completed | Safety of Nerivio in Pregnant Women With Migraine NCT05464069 | Theranica | — |
| Unknown | Botox Vs Spinal Cord Stimulation in the Treatment of Refractory Migraine Clinical Trial NCT05382832 | EPC Education s.r.o. | N/A |
| Completed | A Phase 1 Study to Evaluate the Safety, Tolerability, and Immunogenicity of UB-313 in Healthy Participants NCT05477095 | Vaxxinity, Inc. | Phase 1 |
| Completed | Treatments of Migraine with Triptans in Individuals with Elevated Cardiovascular Risk and in Pregnant Women NCT05854992 | Mayo Clinic | — |
| Completed | A Study of Eptinezumab in Participants With Migraine and Medication Overuse Headache NCT05452239 | H. Lundbeck A/S | Phase 4 |
| Unknown | AVPI Migraine Study NCT05537818 | Nocira, LLC | N/A |
| Recruiting | Determining the Utility of a Behavioral Intervention in Chronic Migraine NCT05415020 | Mayo Clinic | N/A |
| Completed | Effect of a Home-based Versus Supervised Exercise Program in Patients With Migraine NCT05292599 | University of Gran Rosario | N/A |
| Completed | RELAXaHEAD for Headache Patients (Phase II) NCT05466682 | NYU Langone Health | N/A |
| Terminated | Non-pharmacological Treatments in Migraine. NCT05596058 | University of Trieste | N/A |
| Enrolling By Invitation | Studio TIARA: Alessitimia ed Emicrania Cronica NCT06891053 | Azienda Sanitaria Locale di Alessandria | — |
| Completed | Transcranial Direct Current Stimulation Plus Monoclonal Antibodies Acting on the CGRP Pathway for Migraine NCT05161871 | University of L'Aquila | N/A |
| Unknown | Safety and Efficacy of Oral Idebenone for Preventive Treatment of Migraine in Adult Migraine Patients NCT05411978 | Beijing Tiantan Hospital | Phase 4 |
| Completed | A Study Investigating the Movement of Lu AG09222 Into, Through, and Out of the Body of Healthy Caucasian, Chin NCT05304910 | H. Lundbeck A/S | Phase 1 |
| Completed | Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Prevention NCT05207865 | Pfizer | Phase 4 |
| Completed | Influence of Ubrogepant and Sumatriptan on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Cap NCT05654298 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Terminated | Real World Effectiveness of Eptinezumab in Participants With Migraine NCT05284019 | H. Lundbeck A/S | Phase 4 |
| Completed | Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Multiple Dosing Regimens NCT05217927 | Pfizer | Phase 4 |
| Recruiting | Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects NCT05156398 | Pfizer | Phase 3 |
| Unknown | Effectiveness of Multimodal Physical Therapy in Migraine NCT05226559 | Neuromed IRCCS | N/A |
| Recruiting | Monoclonal Antibody Duration of REsponse in MIgraine After Treatment Interruption NCT05232942 | Hospital Clínico Universitario de Valladolid | — |
| Completed | Comparison of Two Different Migraine Acupuncture Treatment NCT05351918 | University Medical Centre Ljubljana | — |
| Unknown | The Effects of Cervical Stabilization Exercise Training With Telerehabilitation in Individuals With Migraine NCT05202171 | Ankara Yildirim Beyazıt University | N/A |
| Enrolling By Invitation | Long-term Extension Study to Assess Safety and Tolerability of Oral Ubrogepant Tablets for the Acute Treatment NCT05127954 | AbbVie | Phase 3 |
| Recruiting | Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migr NCT05125302 | AbbVie | Phase 3 |
| Unknown | Digital-technology Based Interventions on Treatment of Migraine. NCT05458817 | Tartu University Hospital | N/A |
| Completed | New-onset Severe Headache After Covid-19 Vaccine NCT05235776 | Oslo University Hospital | — |
| Completed | Comparison of Wet Cupping and Acupuncture in Migraine NCT05282134 | Karabuk University | N/A |
| Unknown | COMPETE Cohort Study NCT06033937 | Chinese Academy of Medical Sciences, Fuwai Hospital | — |
| Completed | Expectancies in Migraine Patients NCT06633991 | University of Florence | N/A |
| Active Not Recruiting | Study of Pregnancy Outcomes in Women Exposed to Rimegepant During Pregnancy NCT05198245 | Pfizer | — |
| Completed | A Study of Galcanezumab (LY2951742) in Adult Participants With Episodic Migraine NCT05127486 | Eli Lilly and Company | Phase 4 |
| Enrolling By Invitation | Quest to Analyze One Thousand Humans Meditating NCT06583395 | Tobias Moeller-Bertram | — |
| Recruiting | A Study With Eptinezumab in Children and Adolescents (6 to 17 Years) With Chronic or Episodic Migraine NCT05164172 | H. Lundbeck A/S | Phase 3 |
| Withdrawn | Safety and Efficacy of Fremanezumab for Migraine in Adult CADASIL NCT04334408 | Mayo Clinic | Phase 2 |