| Completed | Study to Assess the Bioavailability, Pharmacokinetics, Safety, and Tolerability of AVP-923 in Healthy Adult Pa Healthy Adult Male and Female Volunteers | Phase 1 | 2017-11-28 |
| Terminated | Safety, Tolerability and Efficacy of AVP-786 for the Treatment of Disinhibition Disinhibition Syndrome | Phase 2 | 2015-12-01 |
| Terminated | Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Aff Pseudobulbar Affect (Involuntary Laughing and/or Crying) | Phase 4 | 2015-09-01 |
| Completed | Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Residual Schizophrenia Schizophrenia | Phase 2 | 2015-09-01 |
| Completed | Drug Interaction Study Between AVP-923 and Itraconazole and Between AVP-786 and Itraconazole in Healthy Adult Healthy | Phase 1 | 2015-03-01 |
| Completed | Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Depressive Disorder, Treatment-Resistant | Phase 2 | 2014-07-01 |
| Completed | A Phase 1 Study Comparing AVP-786 With AVP-923 Healthy Volunteer | Phase 1 | 2014-05-01 |
| Completed | Safety and Efficacy of AVP-923 in the Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease Patients Dyskinesia, Parkinson's Disease | Phase 2 | 2013-10-16 |
| Completed | A Phase-1 Study to Assess the Pharmacokinetics, Safety and Tolerability of AVP-786 in Healthy Volunteers Healthy | Phase 1 | 2013-09-01 |
| Completed | Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA) Pseudobulbar Affect (PBA), Stroke, Dementia | Phase 4 | 2013-02-01 |
| Completed | Pharmacokinetics (PK) and Tolerability of AVP-786 in Healthy Volunteers Healthy | Phase 1 | 2012-10-01 |
| Completed | Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of A Agitation, Alzheimer's Disease | Phase 2 | 2012-08-13 |
| Completed | Efficacy and Safety of 20 mg Sumatriptan Powder Delivered Intranasally With the Bi-directional Device Compared Migraine, Headaches | Phase 3 | 2012-08-01 |
| Completed | Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis Central Neuropathic Pain, Multiple Sclerosis | Phase 2 | 2011-09-08 |
| Completed | PRISM Registry: Pseudobulbar Affect Registry Series Alzheimer's Disease, Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS) | — | 2011-05-01 |
| Completed | Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS Pseudobulbar Affect (PBA) | Phase 3 | 2007-12-01 |
| Completed | Safety and Efficacy of Dextromethorphan and Quinidine in the Treatment of the Pain of Diabetic Neuropathy Pain, Diabetic Neuropathy | Phase 3 | 2005-07-01 |
| Completed | Safety Study of AVP-923 in the Treatment of IEED (Involuntary Emotional Expression Disorder) Also Known as Pse Alzheimer's Disease, Stroke, Parkinson's Disease | Phase 3 | 2003-02-01 |
| Completed | Safety and Efficacy of AVP-923 for Pseudobulbar Affect in Multiple Sclerosis Patients Multiple Sclerosis | Phase 3 | 2002-12-01 |
| Completed | Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients Amyotrophic Lateral Sclerosis | Phase 3 | 2001-01-01 |