| Completed | Single Dose Crossover Study to Compare the Respiratory Drive After Administration of Belbuca, Oxycodone and Pl Respiratory Depression | Phase 1 | 2019-07-23 |
| Recruiting | Risk of Major Adverse Cardiovascular Events for Naldemedine & Other Medications for Opioid Induced Constipatio Opioid-induced Constipation | — | 2019-01-04 |
| Completed | Efficacy, Tolerability, and Safety Study of DFN-15 Migraine Headache | Phase 3 | 2016-12-01 |
| Completed | Efficacy, Tolerability, and Safety of DFN-15 Migraine Headache | Phase 3 | 2016-12-01 |
| Completed | The Efficacy and Safety of Clonidine Hydrochloride Topical Gel, vs Clonidine Hydrochloride Gel Comparator to T Painful Diabetic Neuropathy, Diabetic Neuropathy, Neuropathy | Phase 2 | 2015-12-01 |
| Completed | A Safety Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Painful Diabetic Neuropathy Painful Diabetic Neuropathy, Diabetes | Phase 2 | 2014-06-01 |
| Completed | Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Pain Associated With Diabetic Neuropath Painful Diabetic Neuropathy, Diabetic Neuropathy, Neuropathy | Phase 2 | 2014-03-01 |
| Completed | Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Pain | Phase 2 | 2013-06-01 |
| Completed | Long-term Open-Label Safety Study to Evaluate EN3409 Low Back Pain, Osteoarthritis, Neuropathic Pain | Phase 3 | 2012-12-01 |
| Completed | Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Experienced Subjects Low Back Pain | Phase 3 | 2012-09-01 |
| Completed | An Open Label Study To Assess The Safety And Tolerability Of BEMA® Buprenorphine NX In Opioid Dependent Subjec Opioid Dependence | Phase 2 | 2012-08-01 |
| Completed | Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Naive Subjects Low Back Pain | Phase 3 | 2012-08-01 |
| Withdrawn | Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Low Back Pain Pain, Low Back Pain | Phase 3 | 2012-07-01 |
| Completed | Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Pain Pain, Low Back Pain, Osteoarthritis | Phase 3 | 2011-03-01 |
| Completed | Efficacy and Safety Study of Buprenorphine HCl Buccal Film in Subjects With Low Back Pain Pain, Low Back Pain | Phase 3 | 2010-11-01 |
| Completed | Study of Buprenorphine HCl Buccal Film in the Treatment of Dental Pain Dental Pain | Phase 2 | 2009-08-01 |
| Completed | Long-term Extension Study of BEMA™ Fentanyl Respiratory Depression | Phase 3 | 2008-06-01 |
| Completed | Study of BEMA™ Fentanyl in the Treatment of Breakthrough Pain in Cancer Subjects Pain, Cancer | Phase 3 | 2006-02-01 |
| Completed | Study of the Safety of BEMA™ Fentanyl Use for Breakthrough Pain in Cancer Subjects on Chronic Opioid Therapy Pain, Cancer | Phase 3 | 2006-02-01 |
| Withdrawn | The Safety of Using Buprenorphine With Naloxone in a Buccal Film to Initiate Treatment of Opioid Dependent Sub Opioid Dependence | Phase 3 | — |
| Withdrawn | Evaluation of BEMA® Buprenorphine NX for Buprenorphine Induction of Opioid Dependent Subjects Opioid Dependence | Phase 3 | — |