Clinical Trials Directory

Trials / Completed

CompletedNCT01675167

Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Experienced Subjects

Phase 3, Double-Blind, Placebo-Controlled Study to Evaluate the Analgesic Efficacy, Safety, and Tolerability of Buprenorphine HCl Buccal Film in Opioid-Experienced Subjects With Chronic Lower Back Pain Requiring Opioid Analgesia

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
815 (actual)
Sponsor
BioDelivery Sciences International · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to determine if buprenorphine hydrochloride (HCl) buccal film is effective in treating opioid-experienced subjects, with moderate to severe chronic low back pain (CLBP), who require continuous around-the-clock (ATC) pain relief for an extended period of time.

Conditions

Interventions

TypeNameDescription
DRUGBuprenorphineBuprenorphine HCl Buccal Film at doses ranging from 150-900 mcg twice daily
DRUGPlaceboMatching Placebo Buccal Film twice daily

Timeline

Start date
2012-09-01
Primary completion
2014-06-01
Completion
2014-06-01
First posted
2012-08-29
Last updated
2017-02-27
Results posted
2016-02-03

Locations

66 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01675167. Inclusion in this directory is not an endorsement.