| Not Yet Recruiting | Chronic COUGH Management in Interstitial Lung DisEase NCT06782893 | Aveiro University | N/A |
| Not Yet Recruiting | A 2x2 Factorial, Randomized, Open-label Trial to Evaluate Neuromodulators and Cough Control Therapy in Patient NCT07288528 | McMaster University | Phase 4 |
| Recruiting | Efficacy of Behavioral Therapy for Chronic Refractory Cough NCT07488598 | Assiut University | N/A |
| Not Yet Recruiting | Comprehensive Analysis of the Swallowing Mechanism Using High-resolution Manometry With Impedance NCT07365046 | University Hospital Ostrava | N/A |
| Not Yet Recruiting | Biomarkers and Respiratory Omics as New CHildren Opportunities - Study of Clinical Outcomes and Predictivity E NCT07232550 | Medical University of Warsaw | — |
| Not Yet Recruiting | A Prospective, Randomized, Double-blind Study on the Effects of Different Anesthesia Strategies on Postoperati NCT07190664 | Fujian Medical University Union Hospital | N/A |
| Completed | Study to Investigate the Efficacy and Safety of SC0023, in Adults With Refractory or Unexplained Chronic Cough NCT07003347 | Kholood Altassan | N/A |
| Recruiting | The Real-world Treatment Satisfaction by Gefapixiant in RCC NCT06542484 | Nagoya City University | N/A |
| Active Not Recruiting | Efficacy and Safety of ME-015 (Suplatast Tosilate) in Cough Related to Idiopathic Pulmonary Fibrosis (COSMIC-I NCT05983471 | Melius Pharma AB | Phase 2 |
| Recruiting | Single-center Clinical Study on the Safety and Effect of Bronchoscopic Cryotherapy in Patients With Chronic Co NCT06378671 | Guangzhou Medical University | N/A |
| Recruiting | Effect of Gefapixant on Cough-related Brain Activity in Patients With Chronic Cough NCT05813223 | Stuart Mazzone | EARLY_Phase 1 |
| Recruiting | Neuroinflammatory Interactions of ATP and P2X3 Receptor in the Airways of Chronic Cough Patients NCT06286163 | Imperial College London | — |
| Enrolling By Invitation | Etiology Analysis of Chronic Cough After COVID-19 Infection and Research on the Efficacy of ICS or ICS/LABA NCT06503939 | Xiangya Hospital of Central South University | — |
| Recruiting | Analysis of the Reliability and Validity of the Chinese Version of CC-QoL NCT05362097 | Guangzhou Institute of Respiratory Disease | — |
| Completed | Validation Study With a Non-CE Marked Medical Device (MD) NCT05689307 | Siva Health AG | N/A |
| Completed | Study for the Development and Validation of Chronic Cough Patient Perspective Questionnaire NCT05642559 | Ospedale Policlinico San Martino | — |
| Unknown | Cough Suppressive Therapy in Patients With Chronic Cough NCT05522699 | Uppsala University | N/A |
| Recruiting | An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic Cou NCT06376448 | Hull University Teaching Hospitals NHS Trust | — |
| Terminated | Chronic Cough and Small Fiber Neuropathy NCT03787511 | University Hospital, Toulouse | N/A |
| Completed | A Clinical Trial to Evaluate the Safety and Efficacy in Subjects With Chronic Cough NCT05392192 | Aldeyra Therapeutics, Inc. | Phase 2 |
| Completed | A Trial of HRS-2261 in Healthy Subjects After Single and Multiple Oral Administration NCT05274516 | Guangdong Hengrui Pharmaceutical Co., Ltd | Phase 1 |
| Completed | Prospective Study on the Evaluation, Patient Reported Outcomes and Effectiveness of Treatment for Chronic Coug NCT04758351 | McMaster University | — |
| Completed | Mepolizumab for the Treatment of Chronic Cough With Eosinophilic Airways Diseases NCT04765722 | McMaster University | Phase 4 |
| Completed | A Study of Efficacy and Safety of AX-8 in Chronic Cough NCT04866563 | Axalbion SA | Phase 2 |
| Terminated | Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic NCT04654481 | Icahn School of Medicine at Mount Sinai | N/A |
| Unknown | Individualized Diagnosis and Treatment of Extraesophageal Reflux in Patients With Chronic Cough NCT04984304 | University Hospital Ostrava | N/A |
| Completed | Validation and Evaluation of a Novel Cough Detection Device NCT04861155 | Evoleen AG | N/A |
| Unknown | A Multi-center Study to Determine the Prevalence and Influence of Pertussis on Subacute Cough in Shenzhen NCT04694963 | Shenzhen People's Hospital | — |
| Completed | Efficacy and Safety of Gefapixant (MK-7264) in Adult Participants With Recent Onset Chronic Cough (MK-7264-043 NCT04193202 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Efficacy and Safety of Gefapixant (MK-7264) in Women With Chronic Cough and Stress Urinary Incontinence (MK-72 NCT04193176 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Evaluation of S-600918 in Adults With Refractory Chronic Cough NCT04110054 | Shionogi | Phase 2 |
| Completed | A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-030)-China Extension NCT04525885 | Merck Sharp & Dohme LLC | Phase 3 |
| Terminated | A Phase 2b Study of Inhaled RVT-1601 for the Treatment of Persistent Cough in IPF NCT03864328 | Respivant Sciences GmbH | Phase 2 |
| Completed | A Dose Escalation Study of Bradanicline in Refractory Chronic Cough NCT03622216 | Attenua, Inc. | Phase 2 |
| Completed | A Study of Gefapixant (MK-7264) in Japanese Adult Participants With Refractory or Unexplained Chronic Cough (M NCT03696108 | Merck Sharp & Dohme LLC | Phase 3 |
| Unknown | ATP and Capsaicin Cough Provocation Test in Chronic Cough and Bronchiectasis NCT03638063 | Guangzhou Institute of Respiratory Disease | — |
| Completed | Cough in Eastern and Central Finland NCT03639727 | Kuopio University Hospital | N/A |
| Completed | Study of Gefapixant (MK-7264) in Adult Japanese Participants With Unexplained or Refractory Chronic Cough (MK- NCT03482713 | Merck Sharp & Dohme LLC | Phase 2 |
| Completed | A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-030) NCT03449147 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-027) NCT03449134 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Sham CPAP vs. Straight CPAP for Chronic Cough NCT03172130 | Krishna M. Sundar | N/A |
| Unknown | An Open Label Trial of Azithromycin in Chronic Productive Cough NCT02196493 | University of Nottingham | Phase 3 |
| Completed | French Linguistic and Metric Validations of Parent-proxy QOL Chronic Cough Specific Questionnaire (PC-QOL) NCT01865422 | Assistance Publique Hopitaux De Marseille | N/A |
| Unknown | The Use of Capsaicin Challenge for Diagnosis, Monitoring and Follow-up of Chronic Cough. NCT01807832 | Tel-Aviv Sourasky Medical Center | N/A |
| Unknown | Prospective, Comparative, Randomized, Controlled Trial on the Efficacy of the Treatment of Gastroesophageal Re NCT01858584 | Federico II University | N/A |
| Completed | Cough Reflex Sensitivity and Bronchial Hyper-responsiveness NCT01777867 | Mayo Clinic | — |
| Completed | A Study to Assess the Efficacy of Gefapixant (MK-7264/AF-219), in Participants With Chronic Cough (MK-7264-006 NCT01432730 | Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | Phase 2 |
| Unknown | Cough Count Validation NCT01413698 | KarmelSonix Ltd. | — |
| Completed | Lidocaine: Effect of Lidocaine in Chronic Cough NCT01252225 | Manchester University NHS Foundation Trust | Phase 4 |
| Completed | Novel Endpoints in Cough Challenge Testing NCT01566968 | Manchester University NHS Foundation Trust | — |
| Completed | Cough Responses to Tussive Agents in Health and Disease NCT01297790 | Manchester University NHS Foundation Trust | — |
| Completed | Neurophysiology and Pharmacology of Cough Reflex Hypersensitivity NCT00858624 | Jacky Smith | N/A |