NCT03639727

Cough in Eastern and Central Finland

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 61 (actual)
• Sponsor: Kuopio University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Comparison of citric acid and mannitol cough provocation tests among subjects with chronic cough and healthy volunteers.

Detailed description

35 subjects with chronic cough plus 25 subjects without any cough will be asked to participate. The study consists of two visits in the outpatient clinic of Kuopio University Hospital, department of respiratory medicine, 2 - 7 days apart. They will fill in the Leicester Cough Questionnaire and undergo two different cough provocation tests, in random order: Mannitol test and citric acid test. If a chest x-ray has not been taken within 6 months, it will be taken.

Conditions

• Chronic Cough

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Citric acid aerosol bronchial challenge	Inhalation challenge by citric acid aerosol to investigate the subject's cough sensitivity
DIAGNOSTIC_TEST	Mannitol aerosol bronchial challenge	Inhalation challenge by mannitol aerosol to investigate the subject's cough sensitivity

Timeline

• Start date: 2018-09-01
• Primary completion: 2018-12-31
• Completion: 2019-01-31
• First posted: 2018-08-21
• Last updated: 2019-02-12

Locations

1 site across 1 country: Finland