Clinical Trials Directory

Trials / Sponsors / Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Industry · 15 registered clinical trials.

StatusTrialPhaseStarted
CompletedA Multiple-Dose Pharmacokinetics Study of Three Gefapixant (AF-219/MK-7264) Formulations
Healthy
Phase 12016-05-16
CompletedAn 8-Week Refractory Chronic Cough Study (MK-7264-021)
Refractory Chronic Cough
Phase 22015-12-17
CompletedA 12-Week Study in Participants With Refractory Chronic Cough (MK-7264-012)
Refractory Chronic Cough
Phase 22015-12-15
CompletedEffect of Gefapixant (MK-7264/AF-219) on Cough Reflex Sensitivity in Healthy and Chronic Cough Participants (M
Refractory Chronic Cough
Phase 22015-10-28
CompletedA Pharmacokinetics Study of AF-130 in Healthy Subjects
Healthy Volunteers
Phase 12015-10-01
CompletedA Study of Gefapixant (AF-219/MK-7264) in Participants With Idiopathic Pulmonary Fibrosis (IPF) With Persisten
Idiopathic Pulmonary Fibrosis, Cough
Phase 22015-08-26
CompletedA Study to Assess the Tolerability of a Single Dose of Gefapixant (AF-219/MK-7264) in Subjects With Idiopathic
Idiopathic Pulmonary Fibrosis
Phase 22015-07-20
CompletedA Multiple-Dose Pharmacokinetics Study of Two Gefapixant (AF-219/MK-7264) Formulations
Healthy
Phase 12015-07-07
CompletedEffect of Gefapixant (AF-219/MK-7264) on Cough Reflex Sensitivity (MK-7264-015)
Refractory Chronic Cough
Phase 22015-04-29
CompletedA Dose Escalation Study of Gefapixant (AF-219/MK-7264) in Refractory Chronic Cough (MK-7264-010)
Refractory Chronic Cough
Phase 22015-03-09
CompletedA Study to Assess the Effect of Intragastric pH and Fasting on the Pharmacokinetics of Gefapixant (AF-219/MK-7
Healthy Volunteers
Phase 12014-10-06
CompletedA Study to Evaluate the Effect of Gefapixant (AF-219/MK-7264) on Methacholine Hyper-reactivity in Participants
Asthma
Phase 22013-12-16
TerminatedThe Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Female Participants With Interstitial Cystitis /Blad
Bladder Pain Syndrome
Phase 22012-04-13
CompletedA Four-Week Multicenter Study Evaluating the Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Subjects Wi
Osteoarthritis of the Knee
Phase 22012-03-29
CompletedA Study to Assess the Efficacy of Gefapixant (MK-7264/AF-219), in Participants With Chronic Cough (MK-7264-006
Chronic Cough
Phase 22011-09-22