| Not Yet Recruiting | Registry of ENROUTE NPS in Conjunction With Carotid WALLSTENT NCT07458243 | Boston Scientific Corporation | — |
| Recruiting | CAS for Stenosis With High-risk Features for CEA NCT07370246 | Beijing Tiantan Hospital | N/A |
| Not Yet Recruiting | CGUARDIANS III IDE Pivotal Trial NCT07277296 | InspireMD | N/A |
| Recruiting | Balloon Guide Catheter Combined With Filter Protection for Carotid Artery Stenting NCT07247864 | Beijing Anzhen Hospital | N/A |
| Completed | PMCF Study of Precise Pro Rx for Carotid Artery Disease NCT07204678 | Cordis US Corp. | — |
| Not Yet Recruiting | Clinical Trial of PCSK9 Inhibitor and Statin Treatment for Carotid Artery Stenosis NCT07036991 | Changhai Hospital | Phase 4 |
| Recruiting | Study on the Trans-Carotid Artery Occlusion Shunt System NCT06924593 | Shenzhen Wecan Medical Technology Co.,Ltd | N/A |
| Recruiting | A Real-World Study on Ultrasound-Based Screening and Integrated Therapeutic Strategies for Patients With Conco NCT07034157 | Beijing Anzhen Hospital | — |
| Recruiting | Prospective Trial of IVL for Calcified Carotid Lesions(CREATE Trial) NCT06936176 | Shanghai Bluesail Boyuan Medical Technology Co., Ltd. | N/A |
| Recruiting | Prospective Trial of IVL for Calcified Carotid Lesions(CREATE Trial)(Extended Follow-Up) NCT06936189 | Shanghai Bluesail Boyuan Medical Technology Co., Ltd. | — |
| Not Yet Recruiting | Study on PAD and CAS Based on Omics and Imaging NCT06917547 | Yijie Ning | — |
| Recruiting | Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets NCT06959628 | Shenzhen Wecan Medical Technology Co.,Ltd | N/A |
| Completed | Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets NCT06864299 | Shenzhen Wecan Medical Technology Co.,Ltd | N/A |
| Active Not Recruiting | Evaluation of the Ton-bridge Carotid Stent for Carotid Artery Stenosis NCT06365697 | Ton-Bridge Medical Tech. Co., Ltd | N/A |
| Recruiting | Ocular Perfusion in Patients With Unilateral Carotid Artery Stenosis NCT06398223 | Medical University of Vienna | — |
| Not Yet Recruiting | Innovative Application of Pressure Gradient Measurement in Internal Carotid Stenosis in Patients Undergoing CA NCT06123767 | 4th Military Clinical Hospital with Polyclinic, Poland | N/A |
| Recruiting | Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Athero NCT06541691 | Rajaie Cardiovascular Medical and Research Center | N/A |
| Completed | Bacteria in Atherosclerotic Plaques and Adverse Events NCT06935279 | Tang-Du Hospital | — |
| Completed | Safety and Efficacy of Remote Ischemic Conditioning in Patients With Carotid Artery Stenosis Undergoing Caroti NCT06033963 | Yi Yang | N/A |
| Completed | Improved Image Quality for Assessment of Carotid Artery Stenosis by Ultrafast Ultrasound FLOW Imaging NCT06170580 | Radboud University Medical Center | — |
| Recruiting | Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi) NCT05968053 | Beijing Tiantan Hospital | — |
| Recruiting | Revascularization Effect on CSVD Burden in Carotid Artery Stenosis NCT06031610 | Zhejiang Provincial People's Hospital | — |
| Recruiting | Prediction of Cerebral Hyperperfusion Syndrome After Carotid Revascularization Using Deep Learning NCT05800821 | State Institution "Republican Scientific and Practical Center" Cardiology, Belarus | — |
| Unknown | Evaluation of Brain Health and Surgical Efficacy in Patients With Carotid Artery Stenosis NCT05848921 | Nanjing University of Traditional Chinese Medicine | — |
| Unknown | The VANGAS-Trial. The Value of Neurofilament Light Chain and Glial Fibrillary Acid Protein in the Blood of Pat NCT06211725 | Heinrich-Heine University, Duesseldorf | — |
| Completed | Carotid Ultrasound to Identify Head and Neck Cancer Survivors With High Cardiovascular Risk After Radiation Th NCT05490875 | Wake Forest University Health Sciences | — |
| Completed | VFI in Healthy Vessels NCT05451485 | Rijnstate Hospital | — |
| Unknown | Timing Carotid Stent Clinical Study for the Treatment of Carotid Artery Stenosis（Timing Trial） NCT05574972 | Suzhou Zenith Vascular Scitech Co., Ltd. | N/A |
| Active Not Recruiting | Troponin in Carotid Revascularization NCT05293067 | University of Belgrade | — |
| Completed | Effect of Remote Ischemic Preconditioning on Cerebral Circulation Time in Patients With Severe Carotid Artery NCT05451030 | General Hospital of Shenyang Military Region | N/A |
| Completed | Retrospective Study of the Uni-Graft® K DV Patch in the Clinical Routine NCT05117515 | Aesculap AG | — |
| Active Not Recruiting | Progression Assessment of Carotid Artery Stenosis by Ultrafast Ultrasound Flow Imaging NCT05270005 | Rijnstate Hospital | — |
| Recruiting | Acute Stroke of CArotid Artery Bifurcation Origin Treated With Use oF the MicronEt-covered CGUARD (SAFEGUARD-S NCT05195658 | John Paul II Hospital, Krakow | — |
| Completed | Carotid Artery Stenosis and Ischemic Cerebrovascular Events After Radiotherapy in Patients With Head and Neck NCT06556979 | Chulabhorn Royal Academy | — |
| Unknown | Cognitive Function and Brain Connectivity in CAS Patients:a Rs-fMRI Study NCT05292729 | First Affiliated Hospital of Zhejiang University | — |
| Terminated | A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction NCT05126238 | Negovsky Reanimatology Research Institute | Phase 3 |
| Recruiting | Gao's Triple Eversion Carotid Endarterectomy NCT06722222 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Active Not Recruiting | Safety and Efficacy of the CGuard™ Carotid Stent System in Carotid Artery Stenting NCT04900844 | InspireMD | N/A |
| Unknown | Effect of Carotid Artery Stent on Evoked Cerebral Blood Oxygenation and Neurocognitive Functioning NCT04651998 | Shanghai Jiao Tong University Affiliated Sixth People's Hospital | — |
| Unknown | A Study of Evolocumab on Carotid Artery Atherosclerotic Plaque Morphology Prior to Carotid EndArterectomy NCT04539223 | Canadian Medical and Surgical Knowledge Translation Research Group | Phase 4 |
| Active Not Recruiting | Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System NCT04201132 | Contego Medical, Inc. | N/A |
| Recruiting | Change of Hemodynamics and Cerebral Functions After Carotid Artery Revascularization NCT05539781 | Beijing Friendship Hospital | — |
| Completed | Prevalence of Carotid Artery Stenosis and Abdominal Aortic Aneurysms in Brussels: a Population-based Screening NCT04098523 | Erik Debing | N/A |
| Unknown | Effect of Evolocumab on Carotid Plaque Composition in Asymptomatic Carotid Artery Stenosis (EVOCAR-1) NCT03931161 | Imperial College Healthcare NHS Trust | Phase 4 |
| Completed | Sundt™ Carotid Shunt Retrospective Post Market Clinical Follow-up Study (PMCF) NCT03816202 | Integra LifeSciences Corporation | — |
| Unknown | Imaging of Unstable Carotid Plaque in Patient Referred to Endarterectomy NCT03353103 | University Hospital, Caen | Phase 2 |
| Completed | Stratification of Patient With Carotid Disease NCT03495830 | University of Belgrade | — |
| Terminated | Evaluation of a Novel Technique to Diagnose Carotid Artery Stenosis NCT03464851 | The Cleveland Clinic | — |
| Unknown | Safety and Efficacy of Low Dosage of Terazosin in Subjects Undergoing Carotid Artery Stenting NCT03195673 | Capital Medical University | Phase 2 |
| Completed | Evaluation of the 3-in-1 Neuroguard IEP System for Carotid Artery Stenosis NCT04142541 | Contego Medical, Inc. | N/A |
| Completed | Prospective Single Arm CAS - ROADSAVER Study NCT03504228 | Terumo Europe N.V. | — |
| Completed | Time to Post-Anesthesia Neurological Evaluation With Three Different Anesthetic Techniques NCT03996148 | The Cooper Health System | Phase 4 |
| Unknown | High Dose Atorvastatin for Preventing Periprocedural Ischemic Brain Damage During Carotid Artery Stenting NCT03079115 | Beijing Hospital | Phase 4 |
| Completed | Statin Neuroprotection and Carotid Endarterectomy: Safety, Feasibility and Outcomes NCT02850081 | Columbia University | Phase 3 |
| Completed | Hypoxic Preconditioning on Patients NCT02966418 | Hua Yan | N/A |
| Completed | Ticagrelor Versus Clopidogrel in Carotid Artery Stenting NCT02677545 | University Hospital, Basel, Switzerland | Phase 2 |
| Completed | Clinical Study to Evaluate the Safety and Effectiveness of MER® Stents in Carotid Revascularisation. NCT03133429 | Balton Sp.zo.o. | N/A |
| Unknown | Evaluation of the Roadsaver Stent Used in Conjunction With the Nanoparasol Embolic Protection System for Carot NCT02657707 | Microvention-Terumo, Inc. | N/A |
| Completed | A Study of Remote Ischaemic Preconditioning in Patients With Atherosclerosis Undergoing Vascular Surgery NCT02689414 | Tartu University Hospital | N/A |
| Completed | Structural Stability of Carotid Plaque and Symptomatology NCT02476396 | University of Wisconsin, Madison | — |
| Terminated | New Ischemic Cerebral Lesions After Endarterectomy vs. Stenting for the Treatment of Symptomatic Carotid Steno NCT03764306 | Jagiellonian University | N/A |
| Recruiting | Optimization Strategy of Carotid Artery Stenosis NCT05629000 | Peking Union Medical College Hospital | — |
| Unknown | Comparison of Staged Angioplasty and Routine Single-stage Stenting (CAS) in the Treatment of Carotid Artery St NCT02224209 | Beijing Tiantan Hospital | Phase 4 |
| Completed | Body Cooling During Carotid Endarterectomy: No-profit, Open, Mono-centric, Feasibility Study NCT02629653 | S. Andrea Hospital | N/A |
| Completed | The Gore SCAFFOLD Clinical Study NCT01901874 | W.L.Gore & Associates | N/A |
| Withdrawn | Neuropsychological Functioning and Cerebral Perfusion Post Carotid Endarterectomy NCT04759859 | CAMC Health System | — |
| Completed | Enterprise Stent Implantation in the Treatment of Carotid Artery Stenosis With Ischemic Stroke NCT02802072 | Beijing Chao Yang Hospital | N/A |
| Completed | Neuroimaging Correlates of Memory Decline Following Carotid Interventions NCT02006095 | Stanford University | — |
| Completed | Protective Effects of Long-term Remote Limb Ischemic Preconditioning For Carotid Artery Stenting NCT01654666 | Ji Xunming | Phase 2 |
| Unknown | Platelet Reactivity and MES During CEA NCT01547039 | UMC Utrecht | — |
| Unknown | Aortic Calcification - is it a Marker for Carotid Artery Stenosis? NCT01458860 | Ziv Hospital | — |
| Unknown | Impact of Aspiration Thrombectomy During Carotid Stenting NCT01550835 | Fogarty Clinical Research Inc. | N/A |
| Unknown | The Correlation Between the Enzyme Paraoxigenase 1 (PON1) to Carotid Artery Atheromatous Plaque NCT01440036 | Ziv Hospital | — |
| Completed | Long-term Neurocognitive Sequelae of Subclinical Microembolization During Carotid Interventions NCT01718600 | Stanford University | — |
| Unknown | PROximal Protection VErsus NON-Protection in Carotid Artery Stenting NCT01331473 | Universität des Saarlandes | Phase 3 |
| Completed | Ultrasound-guided Intermediate Cervical Plexus Block for Carotid Surgery NCT02450734 | Institut Mutualiste Montsouris | — |
| Terminated | Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease NCT01236508 | Ottawa Heart Institute Research Corporation | Phase 4 |
| Completed | Contrast-enhanced Ultrasound (CE-US) and Magnetic Resonance Imaging (MRI): Evaluating Plaque Neovascularisatio NCT00677963 | Maastricht University Medical Center | N/A |
| Terminated | Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis NCT00805311 | Russian Cardiology Research and Production Center | Phase 4 |
| Completed | GORE® Embolic Filter in Carotid Stenting for High Risk Surgical Subjects (EMBOLDEN) NCT00766493 | W.L.Gore & Associates | Phase 3 |
| Unknown | Predictive Value for Stroke NCT00451529 | Dutch Heart Foundation | — |
| Terminated | Effect of Raised CBF During CEA on Cognition in DM Patients NCT00597545 | Columbia University | N/A |
| Completed | GORE Embolic Protection With Reverse Flow NCT00594100 | W.L.Gore & Associates | Phase 3 |
| Completed | EPIC US Feasibility Study: Use of the FiberNet® Emboli Protection Device in Carotid Artery Stenting NCT00346515 | Lumen Biomedical | N/A |
| Terminated | The Effects of Dexmedetomidine and Remifentanil on Carotid Patients NCT00335972 | The Cleveland Clinic | Phase 4 |
| Completed | Smart Nitinol Stent System for the Treatment of Severe Atherosclerotic Carotid Stenosis NCT02800174 | Beijing Jishuitan Hospital | N/A |
| Completed | EPIC European Study: Use of the FiberNet® Emboli Protection Device in Carotid Artery Stenting NCT00309803 | Lumen Biomedical | N/A |
| Completed | ViVEXX Carotid Revascularization Trial (VIVA) NCT00417963 | C. R. Bard | Phase 3 |
| Completed | A Randomized Trial of Carotid Artery Stenting With and Without Cerebral Protection NCT00177346 | University of Pittsburgh | N/A |
| Completed | Neurological Outcome With Carotid Artery Stenting NCT00597974 | Columbia University | — |
| Completed | Carotid Artery Stenting With Protection Registry NCT00318851 | Providence Health & Services | Phase 3 |
| Completed | Neuropsychometric Outcome After Carotid Endarterectomy NCT00597883 | Columbia University | — |
| Completed | Progression of Carotid Artery Atheroma in Moderately Hypercholesterolemic Subjects NCT00654394 | AstraZeneca | Phase 3 |
| Completed | Randomized Clinical Trial of Polyester vs. Polyurethane Patch for Carotid Endarterectomy NCT02341196 | University of Poitiers | N/A |