NCT05629000

Optimization Strategy of Carotid Artery Stenosis

Cohort of Optimized Assessment Strategy of Carotid Artery Stenosis

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Peking Union Medical College Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this observational study is to learn about how to utilize multiple evaluation techniques in carotid artery stenosis patients for optimizing assessment of diagnosis and treatment strategy. The main questions it aims to answer are: * Identify best strategy that use multi-modal MRI and CT to assess patients' cerebral lesions and perfusion. * Identify best strategy that use multi-modal MRI, PET-MRI ultrasound and CT to assess components and characters of patients' carotid plaques. Participants will accept imaging examination before and after surgery. And doctors will collect basic characteristics, imaging results and biological samples of patients for analysis.

Conditions

• Carotid Artery Stenosis

Interventions

Type	Name	Description
PROCEDURE	Carotid revascularization	All patients received carotid revascularization surgery at Peking Union Medical College Hospital.
DIAGNOSTIC_TEST	MRI-PWI	Multi-modal MRI before and after surgery.
DIAGNOSTIC_TEST	CTA	CTA before and after surgery.
DIAGNOSTIC_TEST	PET/MRI	PET/MRI before surgery.
DIAGNOSTIC_TEST	Ultrasound	Ultrasound before and after surgery.

Timeline

• Start date: 2015-01-01
• Primary completion: 2025-12-31
• Completion: 2026-12-31
• First posted: 2022-11-29
• Last updated: 2022-11-29

Locations

1 site across 1 country: China