| Not Yet Recruiting | Suprazygomatic Maxillary Nerve Block in Pediatric Tonsillectomy NCT07176533 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Completed | Coblation Tonsillectomy Versus Cold Dissection Tonsillectomy NCT07457619 | Shahida Islam Medical Complex | N/A |
| Recruiting | Perspectives on Antibiotics and Tracking Symptoms in Children NCT07093749 | Murdoch Childrens Research Institute | N/A |
| Recruiting | ST250 as a Therapeutic Option for Head & Neck Reconstruction NCT06543823 | Alaa Emara | Phase 1 / Phase 2 |
| Not Yet Recruiting | Study on the Efficacy and Safety of a Device for Post-op Recovery in Pediatric Adenectomy/Adenotonsillectomy. NCT06478433 | Pharmaluce srl | N/A |
| Recruiting | Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia NCT06576830 | Duke University | Phase 4 |
| Recruiting | Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery NCT06326983 | Boston Children's Hospital | N/A |
| Completed | Outcomes of Bipolar Electrocautery Tonsillectomy Versus Cold Steel Dissection Pediatric Tonsillectomy NCT06494839 | RESnTEC, Institute of Research | N/A |
| Recruiting | Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adeni NCT05656365 | National Institute of Allergy and Infectious Diseases (NIAID) | — |
| Recruiting | Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy NCT05575401 | Loma Linda University | N/A |
| Completed | Pediatric Pain Optimization After Tonsillectomy NCT05244226 | Duke University | Phase 2 |
| Terminated | Efficacy and Safety of L. Plantarum and P. Acidilactici in Children With Upper Respiratory Tract Infections NCT05279534 | AB Biotics, SA | N/A |
| Unknown | The Relationship Between Covid-19 Infection in Pediatric Patients and Secondary Lymphoid Organs NCT04646525 | Selcuk University | — |
| Completed | Management of Post-Tonsillectomy Pain in Pediatric Patients NCT04551196 | Washington University School of Medicine | Phase 3 |
| Completed | Evaluation of the Functional Impact of Adenotonsilectomy NCT05532228 | Instituto de Ciências Biomédicas Abel Salazar | — |
| Completed | Intelligent Customer-driven Solution for Children and Their Parents Undergoing Day Surgery NCT04277299 | University of Oulu | N/A |
| Terminated | Opioid-Free Anesthetic for Tonsillectomy NCT04528173 | Children's Hospital of Philadelphia | Phase 4 |
| Unknown | The BLIS Study: a Feasibility Study Assessing Compliance, Acceptability and Colonisation With Different Dosing NCT04297878 | University of Southampton | N/A |
| Completed | Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery NCT04230681 | Washington University School of Medicine | EARLY_Phase 1 |
| Unknown | Does Ice Cream Help With Post-tonsillectomy Pain NCT04164511 | University Hospital Sestre Milosrdnice | — |
| Active Not Recruiting | Intracapsular Tonsillectomy in Adults NCT03654742 | Turku University Hospital | N/A |
| Recruiting | Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and No Antibiotic Treatment NCT04083417 | Katarina Hedin | Phase 4 |
| Unknown | Children Recovering From Tonsil Surgery NCT03292068 | Lund University | N/A |
| Completed | Steroids and Pain Control After Tonsillectomy NCT03995628 | Medical University of South Carolina | Phase 2 |
| Completed | Relationship of Endoplasmic Reticulum Stress and Tonsillar Tissue Diseases NCT04653376 | Selcuk University | — |
| Recruiting | Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy NCT03625011 | Children's Healthcare of Atlanta | Phase 4 |
| Completed | Opioid Use, Storage, and Disposal Among Pediatric Patients After Surgery NCT03575377 | Nationwide Children's Hospital | N/A |
| Unknown | Perioperative Tonsillectomy Protocol Development NCT03323047 | London Health Sciences Centre | Phase 4 |
| Completed | Antimicrobial Stewardship Program (ASP) in Patients With a Sore Throat NCT03408704 | Vastra Gotaland Region | N/A |
| Completed | L. Reuteri ATCC PTA 5289 & L. Reuteri DSM 17938 for the Treatment of Children With Pharyngitis and/or Tonsilli NCT03377374 | Innovacion y Desarrollo de Estrategias en Salud | N/A |
| Completed | Comparison of Dexmedetomidine and Midazolam for Prevention of Emergence Delirium in Children NCT03337672 | Eunah Cho, MD | N/A |
| Unknown | Diagnosis of GABHS Tonsillitis - Comparison Between Culture From Tonsills and Culture From the Bucal Surface NCT03137823 | Bait Balev Hospital | N/A |
| Unknown | Detection of Group A Streptococcus (GAS) in Oral Cavity NCT02972437 | Hadassah Medical Organization | — |
| Unknown | Influence of 0.75% Ropivacaine Topicalization on Emergence Agitation in Children NCT02848287 | Ajou University School of Medicine | N/A |
| Unknown | Effectiveness of Tonsil Fossa Closure in Pain Relief After Tonsillectomy in Children NCT02676583 | Marco Aurelio Fornazieri | N/A |
| Completed | Study of 5 and 10 Days Treatment With Penicillin Against Sore Throat Caused by Streptococci NCT02712307 | Ass. Prof. Katarina Hedin | Phase 4 |
| Completed | EXPAREL® for Pain After Tonsillectomy NCT02444533 | Mayo Clinic | Phase 4 |
| Terminated | The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation NCT02162433 | Massachusetts Eye and Ear Infirmary | Phase 4 |
| Unknown | Continuous Intravenous Sufentanil Infusion for Postoperative Pain Management Following Tonsillectomy or Adeno- NCT02205580 | Jin Ni | Phase 4 |
| Terminated | PASS Study To Evaluate The Potential Of Zithromax To Cause Ocular Problems In Pediatric Patients NCT01919996 | Pfizer | Phase 2 |
| Completed | Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea NCT02571075 | Defense and Veterans Center for Integrative Pain Management | N/A |
| Completed | Improving the Diagnosis of Tonsillitis in Emergency Rooms NCT02858687 | Assistance Publique Hopitaux De Marseille | N/A |
| Completed | Analgesic Effect of IV Acetaminophen in Tonsillectomies NCT01691690 | Nationwide Children's Hospital | Phase 2 |
| Completed | Acetaminophen's Efficacy For Post-operative Pain NCT01721486 | Kaveh Aslani, MD | Phase 4 |
| Completed | Laryngeal Mask Airway in Pediatric Adenotonsillectomy NCT01695980 | Eastern Virginia Medical School | N/A |
| Unknown | Evaluation of Coblation Channeling in Treating Chronic Tonsillitis NCT01193790 | Hillel Yaffe Medical Center | Phase 2 |
| Completed | A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy NCT01267136 | Children's Hospitals and Clinics of Minnesota | Phase 4 |
| Terminated | PEAK PlasmaBlade TnA Versus Traditional Electrosurgery in Subcapsular Tonsillectomy NCT01193556 | Medtronic Surgical Technologies | N/A |
| Withdrawn | Comparison of Floseal Hemostasis Tonsillectomy With Coblation Tonsillectomy and Cautery Hemostasis Tonsillecto NCT00459927 | Kaiser Permanente | Phase 2 / Phase 3 |
| Completed | Investigation of Clinical Spectrum, Bacterial Pathogens and Immune Response in Acute Pharyngotonsillitis NCT00926198 | Johann Wolfgang Goethe University Hospital | — |
| Completed | Vitamin D Levels in Children Undergoing Adenotonsillectomies and Controls NCT00829972 | University of Chicago | — |
| Unknown | Study of Efficacy and Adverse Effects: Vessel Sealing System Tonsillectomy Versus Cold Knife Tonsillectomy NCT00636402 | Chulalongkorn University | N/A |
| Completed | Recurrent Throat Infections and Tonsillectomy NCT00547391 | Oulu University Hospital | Phase 4 |
| Completed | Celecoxib as a Post-tonsillectomy Pain Medication NCT00583453 | University of Iowa | Phase 2 |
| Unknown | Randomized Controlled Study of Plasmaknife Tonsillectomy Versus Monopolar Tonsillectomy NCT00466544 | Children's Hospital of Michigan | Phase 4 |
| Completed | Airway Management in Children Undergoing Adenotonsillectomies NCT00570414 | Sykehuset Telemark | N/A |
| Completed | Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children NCT00393744 | Sanofi | Phase 3 |
| Terminated | TELI TON - Telithromycin in Tonsillitis NCT00315042 | Sanofi | Phase 3 |
| Terminated | TELI TAD - Telithromycin in Tonsillitis in Adolescents and Adults NCT00315549 | Sanofi | Phase 3 |
| Completed | APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat NCT00242281 | Advancis Pharmaceutical Corporation | Phase 3 |
| Completed | Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing Tonsillectomy NCT00654511 | Children's National Research Institute | Phase 4 |
| Completed | Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Sym NCT01361399 | Bayer | Phase 3 |
| Completed | APC-111 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) for 10 Days in Patients With St NCT00095368 | Advancis Pharmaceutical Corporation | Phase 3 |
| Completed | Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections NCT04016051 | Grünenthal GmbH | Phase 3 |
| Completed | Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Th NCT01465009 | Bayer | Phase 4 |
| Completed | A Multicenter, Randomized, Double-Blind, Double-Dummy Study Of Azithromycin SR Versus Amoxicillin For The Trea NCT00643149 | Pfizer | Phase 3 |
| Completed | A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin Sustained Release Vers NCT00644293 | Pfizer | Phase 3 |
| Completed | Multicenter, Open, Randomized Comparative Trial To Compare The Efficacy Of Azithromycin Versus Amoxicillin In NCT00643539 | Pfizer | Phase 4 |
| Unknown | Tonsillectomy in Recurrent Tonsillitis NCT00136877 | Oulu University Hospital | N/A |