Clinical Trials Directory

Trials / Completed

CompletedNCT00644293

A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin Sustained Release Versus 3-Day Azithromycin for the Treatment of Strep Throat in Adolescents and Adults

A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin SR Versus Three-Day Azithromycin for the Treatment of Group A β-Hemolytic Streptococcal Pharyngitis/Tonsillitis in Adolescents and Adults

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
598 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
13 Years
Healthy volunteers
Not accepted

Summary

To determine if a single 2.0-g dose of azithromycin SR is at least as effective as a 3-day course of azithromycin (500 mg once daily for 3 days) when used to treat adolescents and adults with strep throat, and to assess efficacy and safety for both treatment regimens.

Conditions

Interventions

TypeNameDescription
DRUGazithromycin (Zithromax)azithromycin 500 mg tablet by mouth once daily for 3 days
DRUGplaceboplacebo
DRUGazithromycin SRazithromycin SR 2.0 g by mouth as an oral slurry for 1 dose
DRUGplaceboplacebo

Timeline

Start date
2003-01-01
Completion
2004-04-01
First posted
2008-03-26
Last updated
2011-06-08

Locations

59 sites across 10 countries: United States, Belgium, Finland, France, Germany, India, Italy, Netherlands, Norway, United Kingdom

Source: ClinicalTrials.gov record NCT00644293. Inclusion in this directory is not an endorsement.